Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Micronized GL-3 L-Glutamine Ingredients & Drug Interactions

by AST Sports Science

Micronized GL-3 L-Glutamine label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Micronized GL-3 L-Glutamine against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Micronized GL-3 L-Glutamine is a dietary supplement by AST Sports Science with 1 active ingredient. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Micronized GL-3 L-Glutamine by AST Sports Science

Ask about any prescription or over-the-counter medication and we check it for interactions with Micronized GL-3 L-Glutamine by AST Sports Science — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Micronized GL-3 L-Glutamine by AST Sports Science

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-glutamine (in micronized form, meaning the particles are very small for easier mixing and absorption). L-glutamine is an amino acid — one of the building blocks your body uses to make protein.

Your body makes some on its own, but during illness, injury, or intense training, demand can outpace supply.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: strength, size, and recovery support.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Postoperative recovery, Wound healing, Critical illness (trauma), Burns — and 4 related terms.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for Critical illness (trauma) (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Effective" for Postoperative recovery.
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance, Burns.

The evidence shows L-glutamine is effective for sickle cell disease. It's rated possibly effective for HIV/AIDS-related wasting, postoperative (after surgery) recovery, and critical illness from trauma, though the research here is less complete.

For other uses, the data we hold doesn't establish effectiveness.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-glutamine is generally well tolerated by healthy adults when taken by mouth. The most common side effects are gastrointestinal — belching, bloating, gas, nausea, diarrhea, and stomach pain, especially at higher doses (10–30 grams daily).

Headache and dizziness have also been reported; one person's dizziness improved when the dose was cut in half. In two patients with bipolar disorder, high doses triggered mania or hypomania, so those with a bipolar history should be cautious.

If you have kidney or liver disease, use L-glutamine only under medical supervision. There isn't enough safety data to recommend it during pregnancy or while breastfeeding unless your doctor advises it — talk with them if you're planning either.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Anticonvulsants (seizure medications) — glutamine may theoretically reduce their effectiveness. Check your exact anticonvulsant with your doctor or pharmacist before taking this supplement.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

L-glutamine is a good fit if you're recovering from surgery, dealing with critical illness, or managing HIV/AIDS-related muscle wasting, or if you have sickle cell disease. If you take anticonvulsants (seizure medications), check with your doctor or pharmacist first — the theory is that glutamine could interfere with those drugs.

Stomach upset is common, especially at higher doses.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Micronized GL-3 L-Glutamine, straight from the product label.

Brand AST Sports Science
Barcode (UPC) 705077002789
Net contents 525 Gram(s); 18.52 oz.
Market status On market
Date entered into DSLD May 24, 2017
DSLD ID 73652
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Micronized GL-3 L-Glutamine by AST Sports Science, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 tsp
Maximum serving Sizes:
2 tsp
Servings per container
53
UPC/BARCODE
705077002789
IngredientAmount% DV
L-Glutamine10 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

10g Per serving 53 Total servings 20x Particle micronization technology Strength Size Recovery

Each tiny particle of GL3 is 20 times smaller than regular glutamine powder. This allows for ultra-fast absorption and utilization. Glutamine represents over 63% of the amino acid content in the amino acid pool of muscle tissue. Intense training and exercise put greater demands on your body for glutamine, making it a conditionally essential amino acid. Glutamine is the most common amino acid in the body and is key to the metabolism and maintenance of muscle tissue. Glutamine is also the highest concentrated amino acid in the muscle cell and acts as a primary shuttle for nitrogen from the bloodstream to inside the muscle cell. Glutamine has a multifaceted role in human nutrition and is essential for the support of muscle tissue and immune function.

Contents packaged by weight - not volume. Some settling may occur.

Made in USA

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Micronized GL3 L-Glutamine represents a leap forward in glutamine supplementation. GL3 uses a state-of-the-art particle micronization technology (PMT).

Copyright 2016 AST Sports Science

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Suggested/Recommended/Usage/Directions

Recommended Use: As a dietary supplement, mix 2 teaspoons (10 grams) in 6 to 8 oz. of water or juice. Drink 1 serving 30 minutes before training and 1 serving 30 minutes after training.

General

REV# GL35-516

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Micronized GL-3 L-Glutamine by AST Sports Science label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Micronized GL-3 L-Glutamine label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Micronized GL-3 L-Glutamine by AST Sports Science

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 tsp Dosage formPowder Servings per container53 Amounts shown are per serving.

L-Glutamine

Interacts with
50 drugs
10 Gram(s) per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions
Interaction report

Micronized GL-3 L-Glutamine by AST Sports Science Drug Interactions

Want to check YOUR meds against Micronized GL-3 L-Glutamine?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

L-Glutamine 50

Individual Drug Interactions

The ingredients in Micronized GL-3 L-Glutamine interact with 50 drugs. Click any drug to see the details.

1 of the 1 ingredient in Micronized GL-3 L-Glutamine interact with drugs. Each result below shows which ingredient is responsible. L-Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in Micronized GL-3 L-Glutamine with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Micronized GL-3 L-Glutamine, from the product label.

AST Sports Science

See all AST Sports Science products
Name
AST Sports Science
Street Address
120 Capital Drive
City
Golden
State
CO
ZipCode
80401
Phone Number
1-800-627-2788
Web Address
www.ast-ss.com
Pharmacist Counseling Corner

Micronized GL-3 L-Glutamine by AST Sports Science: Common Questions

Does Micronized GL-3 L-Glutamine by AST Sports Science interact with any medications?
Yes. Based on its ingredients, Micronized GL-3 L-Glutamine has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Micronized GL-3 L-Glutamine contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does L-glutamine do in the body?
L-glutamine is an amino acid your body uses to build protein and fuel cells, especially during stress, illness, or intense exercise. Your body makes some, but supplementing aims to top up the supply when demand is high — like after surgery, during critical illness, or with certain diseases like sickle cell disease and HIV/AIDS-related wasting.
What are the most common side effects?
Gastrointestinal upset is most frequent — gas, bloating, nausea, diarrhea, and stomach pain. Headache and dizziness have also been reported. These effects are usually mild and more likely at higher doses. If you notice side effects, try a lower dose or talk to your pharmacist.
Is it safe during pregnancy or while breastfeeding?
There isn't enough reliable safety data to know for sure. The data we hold rates it likely safe in pregnancy, but there's little information for breastfeeding. If you're pregnant or nursing, talk with your doctor or pharmacist before taking supplemental glutamine doses.
Who shouldn't take this?
Anyone with kidney or liver disease should use it only under medical supervision. If you have bipolar disorder, be cautious — a few cases of mania have been reported. If you take anticonvulsants (seizure medications), check with your doctor or pharmacist first.
Does it come with any fillers or other inactive ingredients?
No inactive ingredients are listed for this product — it's pure L-glutamine powder.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Micronized GL-3 L-Glutamine is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Micronized GL-3 L-Glutamine label
Go deeper

The Full Monographs Behind Micronized GL-3 L-Glutamine’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph →
Sources

Sources & How We Checked

Micronized GL-3 L-Glutamine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team