Major interaction on record — check this product against your medications before combining. Based on 5 of 10 ingredients. Check your meds →
Dietary supplement

Natural Protein Vanilla Bean Ingredients & Drug Interactions

by NS Natural Stacks

Natural Protein Vanilla Bean label
See full label image
Powder Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Natural Protein Vanilla Bean against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Natural Protein Vanilla Bean is a dietary supplement by NS Natural Stacks with 10 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 273 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Sodium, Potassium, Proserum Whey Protein concentrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Natural Protein Vanilla Bean by NS Natural Stacks

Ask about any prescription or over-the-counter medication and we check it for interactions with Natural Protein Vanilla Bean by NS Natural Stacks — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Natural Protein Vanilla Bean by NS Natural Stacks

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 8 of its 8 active ingredients.
  • “2:1 Whey/Collagen Complex” is a proprietary blend — the label gives one combined amount (18 Gram(s)) without saying how much of each component you get.

Natural Protein Vanilla Bean contains 8 ingredients, including the active proteins sodium, potassium, lactoferrin, bovine colostrum, and whey protein concentrate, along with a 2:1 whey-to-collagen complex. The whey protein is designed to provide amino acids for muscle and general protein nutrition; lactoferrin and colostrum are included for immune and digestive support based on traditional use and some clinical research.

Sodium and potassium are electrolytes that help maintain fluid balance and nerve function. The powder also contains ground Madagascar vanilla for flavor and several other ingredients (immunoglobulins, hydrolyzed bovine collagen, and serum albumin) that contribute to the protein profile.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle building recovery and physical performance.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Physical performance, Muscle strength, Sarcopenia, Wound healing — and 2 related terms.
  • The strongest evidence on file: Whey Protein is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Bovine Colostrum is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Muscle strength, Wound healing, Physical performance.
  • Also on file: Whey Protein is rated "Insufficient Reliable Evidence To Rate" for Sarcopenia, Exercise-induced muscle damage.

Evidence for this product's active ingredients is mixed and limited. Whey protein is possibly effective for athletic performance but shows no clear benefit for bone health or lung function in existing studies.

Lactoferrin is possibly effective for sepsis and pregnancy-related iron deficiency but likely ineffective for reducing infant mortality. Bovine colostrum is possibly effective for exercise-induced respiratory infections and certain types of diarrhea in HIV patients but likely ineffective for preventing necrotizing enterocolitis (a serious bowel condition in newborns).

The effectiveness ratings for sodium and potassium are tied to specific medical conditions (cystic fibrosis, lithium dosing, congestive heart failure) and don't apply to general protein supplementation. Overall, evidence for this product as a general-purpose protein powder is not established in the data we hold.

The evidence, ingredient by ingredient Sodium Potassium Lactoferrin Bovine Colostrum Whey Protein

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Whey protein is generally well tolerated by most healthy adults at typical doses and causes only mild, dose-related side effects like bloating, nausea, diarrhea, headache, and cramps in some people. Acne has been reported by a small number of users, especially teenagers, and resolved after stopping the product.

Lactoferrin is well tolerated at usual doses but tolerability decreases at higher intakes of 7.2 grams daily; gastrointestinal upset and fatigue are the most common complaints. Bovine colostrum is generally well tolerated and causes only mild bloating and nausea in a few trial participants, though it should be avoided if you have a milk or dairy allergy.

Sodium in normal food amounts is fine, but high intake is linked to high blood pressure, heart strain, and kidney disease — and this powder adds sodium beyond your diet. Potassium from food is safe, but supplements can cause dangerously high blood potassium levels, especially in people with kidney disease.

Safety during pregnancy and breastfeeding is not fully established for most ingredients; check with your doctor or pharmacist before use if you are pregnant or nursing.

Side effects, ingredient by ingredient Sodium Potassium Lactoferrin Bovine Colostrum Whey Protein

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 3 of the 5 matched ingredients can interact with medications — Whey Protein, Potassium, Sodium.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: lithium; Parkinson's medications.
  • For scale: 273 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take levodopa (for Parkinson's disease), do not use this product without checking with your doctor or pharmacist first — whey protein is Major severity for this interaction. Also check before use if you take blood pressure medications (antihypertensives), potassium-sparing diuretics, ACE inhibitors, ARBs, quinolone or tetracycline antibiotics, bisphosphonates, lithium, corticosteroids, or any sodium-containing or potassium-containing drugs — these are all Moderate severity interactions with sodium, potassium, or whey protein in this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This protein powder is a multi-ingredient formula best suited for adults looking for whey protein with added colostrum and lactoferrin. If you take blood pressure medications, diuretics, ACE inhibitors, ARBs, levodopa, lithium, or any antibiotic, or if you have kidney disease or high blood pressure, talk with your doctor or pharmacist before starting — the sodium and potassium content, plus the whey protein interactions, need to be checked against your specific situation.

Pregnant or breastfeeding women should clear it with their healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Natural Protein Vanilla Bean, straight from the product label.

Brand NS Natural Stacks
Barcode (UPC) 701698826506
Net contents 1 lb; 454 Gram(s)
Market status On market
Date entered into DSLD Nov 21, 2016
DSLD ID 66735
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Natural Protein Vanilla Bean by NS Natural Stacks, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
19.1 Gram(s)
Maximum serving Sizes:
19.1 Gram(s)
Servings per container
24
UPC/BARCODE
701698826506
IngredientAmount% DV
Calories77.2 Calorie(s)--
Total Carbohydrates1.4 Gram(s)1%
Sugar12 Gram(s)--
Calories from Fat5.4 Calorie(s)--
Protein15.1 Gram(s)30%
Saturated Fat0.4 Gram(s)3%
Sodium48 mg2%
Potassium62 mg2%
Cholesterol14 mg4%
Total Fat0.6 Gram(s)1%
Lactoferrin428 mg--
Immunoglobulins1564 mg--
hydrolyzed Bovine Collagen6 Gram(s)--
Bovine Colostrum500 mg--
Serum Albumin492 mg--
2:1 Whey/Collagen Complex18 Gram(s)--
Proserum Whey Protein concentrate12 Gram(s)--

Other ingredients: ground Madagascar Vanilla

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Natural Protein is a 2 to 1 ratio of whey to collagen protein from grass fed cows that graze year-round on natural pastures.

Natural Protein combines the finest minimally processed sugar nutrients for optimal physical performance: - Whey to boost the immune system & build lean muscle - Collagen to expedite recovery & repair connective tissue - Colostrum for extra regenerative growth factors - Madagascar Vanilla Bean to reduce inflammation

2:1 Whey/Collagen

Formulation

Natural Protein is a 2 to 1 ratio of whey to collagen protein from grass fed cows that graze year-round on natural pastures. It's GMO-free, hormone-treatment-free, and antibiotic-free.

No preservatives No artificial colors No gluten No GMO

Brand IP Statement(s)

The Finest Proserum Native Whey Protein

Proserum is a registered trademark of Wisdom Proteins, Inc. Proserum is minimally processed to best maintain the full range of fragile immune-modulating regenerative components naturally present in fresh raw milk.

Seals/Symbols

U.S.A. manufactured in a cGMP facility.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

From grass-fed cows

Note: Product packed with a nontoxic desiccant.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Mix 1 scoop with 6 oz of cold water or blend into your favorite smoothie. Scoop included.

Precautions

Warning: Consult a healthcare practitioner before taking this or any nutritional supplement if you are pregnant/nursing, have or suspect a medical condition, are taking any medications, or other non-Natural Stacks dietary supplements.

Do not use is safety seal is broken or missing.

Storage

Store in a cool dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Natural Protein Vanilla Bean by NS Natural Stacks label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Natural Protein Vanilla Bean label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Natural Protein Vanilla Bean by NS Natural Stacks

These are the 10 active ingredients this product is made of. Select any to open its full monograph.

Serving size19.1 Gram(s) Dosage formPowder Servings per container24 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

12 Gram(s) per serving

Protein

15.1 Gram(s) per serving

Sodium

Interacts with
205 drugs
48 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Potassium

Interacts with
62 drugs
62 mg per serving

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Lactoferrin

No known
interactions
428 mg per serving

Lactoferrin is an iron-binding protein found naturally in milk and other body fluids, and supplements are usually made from cow's milk or rice. It is...

Lactoferrin monograph & interactions

Immunoglobulins

1564 mg per serving

Bovine Colostrum

No known
interactions
500 mg per serving

Bovine colostrum is the nutrient-rich first milk from cows, packed with antibodies, growth factors, and protein. Early research suggests it may help w...

Bovine Colostrum monograph & interactions

Serum Albumin

492 mg per serving

2:1 Whey/Collagen Complex

18 Gram(s) per serving

Other (inactive) ingredients: Ground Madagascar Vanilla. These complete the product’s ingredient list but are not active constituents.

Interaction report

Natural Protein Vanilla Bean by NS Natural Stacks Drug Interactions

Want to check YOUR meds against Natural Protein Vanilla Bean?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
273Drugs
5 Major 268 Moderate

Ingredients driving the most interactions

Sodium 205
Potassium 62
Proserum Whey Protein concentrate 53

Individual Drug Interactions

The ingredients in Natural Protein Vanilla Bean interact with 273 drugs. Click any drug to see the details.

3 of the 10 ingredients in Natural Protein Vanilla Bean interact with drugs. Each result below shows which ingredient is responsible. Sodium Potassium Proserum Whey Protein concentrate

Each ingredient & the kinds of drugs it affects

For each ingredient in Natural Protein Vanilla Bean with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium full monograph & interactions

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
Potassium full monograph & interactions

Proserum Whey Protein concentrate4 drug types · 53 drugs

Levodopa

Theoretically, whey protein might decrease levodopa absorption.
Small clinical studies show that concomitant ingestion of protein or high doses of leucine or isoleucine (100 mg/kg) and levodopa can exacerbate tremor, rigidity, and the "on-off" syndrome in patients with Parkinson disease.

Likelihood Probable Evidence D
Bisphosphonates

Theoretically, whey protein might reduce the absorption of bisphosphonates.
Whey protein contains minerals such as calcium that bind bisphosphonates in the gut. Advise patients to take bisphosphonates at least 30 minutes before whey protein, but preferably at a different time of day.

Likelihood Probable Evidence D
Quinolone Antibiotics

Theoretically, whey protein might decrease quinolone absorption.
Whey protein contains minerals, such as calcium, that can bind to quinolones in the gut. To avoid this interaction, advise patients to take oral quinolones at least 2 hours before or 4-6 hours after whey protein.

Likelihood Probable Evidence D
Tetracycline Antibiotics

Theoretically, whey protein might decrease tetracycline absorption.
Whey protein contains minerals, such as calcium, that bind to tetracyclines in the gut. To avoid this interaction, advise patients to take oral tetracyclines at least 2 hours before or 4-6 hours after whey protein.

Likelihood Probable Evidence D
Proserum Whey Protein concentrate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Natural Protein Vanilla Bean, from the product label.

NS Natural Stacks

See all NS Natural Stacks products
Name
Natural Stacks Inc.
Street Address
16192 Coastal Hwy
City
Lewes
State
DE
ZipCode
19958
Phone Number
1-855-678-2257
Web Address
www.naturalstacks.com
Pharmacist Counseling Corner

Natural Protein Vanilla Bean by NS Natural Stacks: Common Questions

Does Natural Protein Vanilla Bean by NS Natural Stacks interact with any medications?
Yes. Based on its ingredients, Natural Protein Vanilla Bean has a known interaction with 273 medications, including 5 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Natural Protein Vanilla Bean contains 10 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this powder have a lot of sodium?
The product facts don't specify the exact sodium amount per serving, so check the nutrition label. What we know is that sodium in this product adds to your dietary intake — high total sodium intake is linked to high blood pressure and heart strain, and this product plus your diet could exceed safe levels. If you take blood pressure meds or have high blood pressure, ask your doctor or pharmacist whether the sodium content is okay for you.
Can I use this while I'm taking antibiotics?
It depends on which antibiotic. Whey protein can interfere with quinolone antibiotics (like ciprofloxacin) and tetracycline antibiotics (like doxycycline) by binding them in your gut and reducing how well they're absorbed. If you're on one of these, take your antibiotic at least 2 hours before or 4–6 hours after the protein powder. Talk with your pharmacist to confirm your specific antibiotic and timing.
Is this safe during pregnancy?
Safety data are not fully established for most of the ingredients in this product during pregnancy. Sodium is possibly unsafe in pregnancy per our data, and bovine colostrum and lactoferrin have limited pregnancy safety information. Talk with your doctor or pharmacist before using this product if you're pregnant — they can weigh the ingredient profile against your individual health.
What does lactoferrin do?
Lactoferrin is a natural protein found in milk, saliva, and tears that plays a role in immune function. In this product it's included for immune support, and research suggests it may be possibly effective for certain infections and pregnancy-related iron deficiency — but evidence is limited and not established for general health use.
Will this help my athletic performance?
Whey protein is possibly effective for athletic performance according to clinical evidence, making it the ingredient most likely to support that goal. Lactoferrin and bovine colostrum are included for other purposes (immune and digestive support), and their benefit for athletic performance is not documented in our data.
Can I take this if I have kidney disease?
Both sodium and potassium in this product need careful management in kidney disease because your kidneys regulate their blood levels. High intake of either can be harmful. Do not use this product without talking to your doctor or pharmacist first — they need to know your kidney function and current medications before you add it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Natural Protein Vanilla Bean is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Natural Protein Vanilla Bean label
Go deeper

The Full Monographs Behind Natural Protein Vanilla Bean’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph → Herb & supplement monograph

Lactoferrin

Lactoferrin is an iron-binding protein found naturally in milk and other body fluids, and supplements are usually made from cow's milk or rice. It is being studied for immune support, iron l...

Read the full Lactoferrin monograph → Herb & supplement monograph

Bovine Colostrum

Bovine colostrum is the nutrient-rich first milk from cows, packed with antibodies, growth factors, and protein. Early research suggests it may help with gut health, certain types of diarrhe...

Read the full Bovine Colostrum monograph → Herb & supplement monograph

Whey Protein

Interacts with 53 drugs

Whey protein is a high-quality, complete protein made from cow's milk that can help people meet protein needs and support muscle growth when combined with exercise. It is generally safe for...

Read the full Whey Protein monograph →
Sources

Sources & How We Checked

Natural Protein Vanilla Bean's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 89 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sodium 38 references
  1. Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
  2. Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
  3. Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
  4. Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol 2011;111(2):537-542. PubMed
  5. Frings-Meuthen P, Baecker N, Heer M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 2008;23(4):517-524. PubMed
  6. Alam S, Johnson AG. A meta-analysis of randomised controlled trials (RCT) among healthy normotensive and essential hypertensive elderly patients to determine the effect of high salt (NaCl) diet of blood pressure. J Hum Hypertens 1999;13(6):367-74.
  7. Boudville N, Ward S, Benaroia M, House AA. Increased sodium intake correlates with greater use of antihypertensive agents by subjects with chronic kidney disease. Am J Hypertens 2005;18(10):1300-5. PubMed
  8. Bennett WM. Drug interactions and consequences of sodium restriction. Am J Clin Nutr 1997;65(2 Suppl):678S-681S. PubMed
  9. Okusa MD, Crystal LJ. Clinical manifestations and management of acute lithium intoxication. Am J Med 1994;97(4):383-9. PubMed
  10. Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for water, potassium, sodium, chloride, and sulfate. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/openbook.php?record_id=10925. DOI
  11. D'Elia L, Rossi G, Ippolito R, Cappuccio FP, Strazzullo P. Habitual salt intake and risk of gastric cancer: a meta-analysis of prospective studies. Clin Nutr 2012;31(4):489-98. PubMed
  12. Goldsmith SR. Hyponatremia in heart failure: time for a trial. J Card Fail 2013;19(6):398-400. PubMed
  13. Willocks L, Brettle R, Keen J, Valentine C, Pinching AJ. Formulations of didanosine (ddI) and salt overload. Lancet 1992;339(8786):190.
  14. Chen L, Zhang Z, Chen W, Whelton PK, Appel LJ. Lower Sodium Intake and Risk of Headaches: Results From the Trial of Nonpharmacologic Interventions in the Elderly. Am J Public Health. 2016;106(7):1270-5. PubMed
  15. Cook NR, Appel LJ, Whelton PK. Lower levels of sodium intake and reduced cardiovascular risk. Circulation. 2014;129(9):981-9. PubMed
  16. Cook NR, Appel LJ, Whelton PK. Sodium Intake and All-Cause Mortality Over 20 Years in the Trials of Hypertension Prevention. J Am Coll Cardiol. 2016;68(15):1609-1617. PubMed
  17. Mente A, O'Donnell M, Rangarajan S, et al. Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies. Lancet. 2016;388(10043):465-75. PubMed
  18. Moosavian SP, Haghighatdoost F, Surkan PJ, Azadbakht L. Salt and obesity: a systematic review and meta-analysis of observational studies. Int J Food Sci Nutr. 2017;68(3):265-277. PubMed
  19. O'Donnell M, Mente A, Rangarajan S, et al. Urinary sodium and potassium excretion, mortality, and cardiovascular events. N Engl J Med. 2014;371(7):612-23. DOI
  20. Poggio R, Gutierrez L, Matta MG, Elorriaga N, Irazola V, Rubinstein A. Daily sodium consumption and CVD mortality in the general population: systematic review and meta-analysis of prospective studies. Public Health Nutr. 2015;18(4):695-704. PubMed
  21. Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad
  22. Mahtani KR, Heneghan C, Onakpoya I, et al. Reduced Salt Intake for Heart Failure: A Systematic Review. JAMA Intern Med. 2018 Dec 1;178(12):1693-1700. PubMed
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See these in context on the Sodium monograph →

Potassium 12 references
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See these in context on the Potassium monograph →

Lactoferrin 6 references
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Bovine Colostrum 8 references
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See these in context on the Bovine Colostrum monograph →

Whey Protein 25 references
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  19. Carcillo, J. A., Dean, J. M., Holubkov, R., Berger, J., Meert, K. L., Anand, K. J., Zimmerman, J., Newth, C. J., Harrison, R., Burr, J., Willson, D. F., and Nicholson, C. The randomized comparative pediatric critical illness stress-induced immune suppres
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See these in context on the Whey Protein monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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