Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Noxylane4 Double Strength Ingredients & Drug Interactions

by LaneInnovative

Noxylane4 Double Strength label
See full label image
Other (e.g. Tea Bag) Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Noxylane4 Double Strength against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Noxylane4 Double Strength is a dietary supplement by LaneInnovative with 2 active ingredients. Its ingredients are commonly taken for blood sugar support, digestive and gut health (prebiotic), cholesterol and triglyceride support.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Arabinoxylane Compound Proprietary Blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Noxylane4 Double Strength by LaneInnovative

Ask about any prescription or over-the-counter medication and we check it for interactions with Noxylane4 Double Strength by LaneInnovative — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Noxylane4 Double Strength by LaneInnovative

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 3 active ingredients.
  • “Arabinoxylane Compound Proprietary Blend” is a proprietary blend — the label gives one combined amount (1,000 mg) without saying how much of each component you get.

Noxylane4 Double Strength has 3 active ingredients: rice bran, HAI Amino Acid Extract, an arabinoxylane proprietary blend, and a hyphomycetes mycelia enzyme. The product also contains inactive ingredients — microcrystalline cellulose, croscarmellose sodium, stearic acid, silica, magnesium stearate, hydroxypropyl methyl cellulose, and polyethylene glycol — which are fillers and binders.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: immune defense.
  • We looked for evidence on: immune function, infection prevention, immune response.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

Rice bran is possibly effective for dyslipidemia (abnormal blood fat levels). The evidence is less clear for other uses: it is rated possibly ineffective for colorectal cancer prevention, and there is insufficient evidence to rate it for alopecia areata (patchy hair loss).

We hold no effectiveness data for the other ingredients in this product.

The evidence, ingredient by ingredient Arabinoxylan Rice Bran

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, rice bran is generally well tolerated. The main concern is digestive: increasing dietary bran can cause temporary abdominal discomfort, bloating, and irregular bowel habits, especially in the first few weeks.

Allergic reactions are rare but can occur — urticaria (hives), itching, swelling, wheezing, and cough have been reported; in very rare cases, anaphylaxis (a severe allergic reaction) has happened after consuming large amounts. Rice bran is rated likely safe in pregnancy and lactation.

We hold no safety data for HAI Amino Acid Extract, the arabinoxylane blend components, or Hyphomycetes mycelia enzyme, and safety information on concentrated supplement doses of rice bran is limited, so talk with your doctor before starting if you are pregnant, breastfeeding, or have a history of food allergies.

Side effects, ingredient by ingredient Arabinoxylan Rice Bran

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. However, we hold no interaction information for HAI Amino Acid Extract, the arabinoxylane blend, or Hyphomycetes mycelia enzyme, so double-check your exact medications with your pharmacist or doctor before starting.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Noxylane4 Double Strength may be worth considering if you're looking to support healthy blood fat levels — rice bran has some evidence for that. Watch out for digestive upset and rare allergic reactions, especially if you have a known rice allergy.

Because we couldn't check all the ingredients and supplement-dose safety data is sparse, talk it over with your doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Noxylane4 Double Strength, straight from the product label.

Brand LaneInnovative
Barcode (UPC) 002110600224
Net contents 50 Caplet(s)
Market status On market
Date entered into DSLD Jul 23, 2020
DSLD ID 230672
Product type Other Combinations
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Noxylane4 Double Strength by LaneInnovative, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Caplet(s)
Maximum serving Sizes:
2 Caplet(s)
Servings per container
25
UPC/BARCODE
002110600224
IngredientAmount% DV
Calories4 Calorie(s)--
Total Carbohydrates1 Gram(s)1%
Total Fat1 Gram(s)1%
Rice Bran0 NP--
HAI Amino Acid Extract1 mg--
Arabinoxylane Compound Proprietary Blend1000 mg--
Hyphomycetes mycelia enzyme0 NP--

Other ingredients: Microcrystalline Cellulose, Croscarmellose Sodium, Stearic Acid, Silica, Magnesium Stearate, Hydroxy Propyl Methyl Cellulose, Polyethylene Glycol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Noxylane4 is the next generation in immune defense from LaneInnovative.

This product contains no animal by-products.

HAI Potentiated Clinically shown to support NK Cell Activity

Formula

It contains Arabinoxylane - a rice bran hemicellulose modified by Shitake mushroom enzymes - and HAI. Heated Algal Ingredient (HAI) is an amino acid complex from Japanese seaweed that appears to enhance absorption.

(500 mg Arabinoxylane with HAI)

Suggested/Recommended/Usage/Directions

Suggested use for adult: Daily wellness: Take 1 to 2 caplets daily.

Storage

Store in a cool dry place.

Precautions

Keep out of reach of children.

Do not use if bottle seal is broken or missing.

Consult a health care professional first if you are pregnant or nursing.

General Statements

LaneInnovative Since 1994

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

GMP Good Manufacturing Practice Quality Product

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Noxylane4 Double Strength by LaneInnovative label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Noxylane4 Double Strength label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Noxylane4 Double Strength by LaneInnovative

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Caplet(s) Dosage formOther (e.g. Tea Bag) Servings per container25 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

HAI Amino Acid Extract

1 mg per serving Form: Sea Algae

Arabinoxylane Compound Proprietary Blend

Interacts with
86 drugs
1000 mg per serving

Arabinoxylan is a type of dietary fiber found in cereal grains that acts as a prebiotic and may modestly affect blood sugar and blood fats. The eviden...

Arabinoxylane Compound Proprietary Blend monograph & interactions
  • › Rice Bran
  • › Hyphomycetes mycelia enzyme

Other (inactive) ingredients: Microcrystalline Cellulose, Croscarmellose Sodium, Stearic Acid, Silica, Magnesium Stearate, Hydroxy Propyl Methyl Cellulose, Polyethylene Glycol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Noxylane4 Double Strength by LaneInnovative Drug Interactions

Want to check YOUR meds against Noxylane4 Double Strength?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Arabinoxylane Compound Proprietary Blend 86

Individual Drug Interactions

The ingredients in Noxylane4 Double Strength interact with 86 drugs. Click any drug to see the details.

1 of the 2 ingredients in Noxylane4 Double Strength interact with drugs. Each result below shows which ingredient is responsible. Arabinoxylane Compound Proprietary Blend

Each ingredient & the kinds of drugs it affects

For each ingredient in Noxylane4 Double Strength with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Arabinoxylane Compound Proprietary Blend1 drug type · 86 drugs

Antidiabetes Drugs

Evidence from human research suggests that an arabinoxylan-rich fiber can reduce postprandial glucose levels. Theoretically, arabinoxylan might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia. Monitor blood glucose levels closely. Dose adjustments might be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence B
Arabinoxylane Compound Proprietary Blend full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Noxylane4 Double Strength, from the product label.

LaneInnovative

See all LaneInnovative products
Name
LaneInnovative, Inc.
City
Vero Beach
State
FL
ZipCode
32964
Phone Number
1-800-526-3005
Web Address
www.laneinnovative.com
Pharmacist Counseling Corner

Noxylane4 Double Strength by LaneInnovative: Common Questions

Does Noxylane4 Double Strength by LaneInnovative interact with any medications?
Yes. Based on its ingredients, Noxylane4 Double Strength has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Noxylane4 Double Strength contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this cause digestive problems?
Rice bran can cause temporary abdominal discomfort, bloating, and irregular bowel habits when you first start, especially if you're adding a lot at once. These effects usually settle down after a few weeks as your body adjusts.
Is it safe if I have a rice allergy?
Rice bran can trigger allergic reactions in sensitive people — hives, itching, swelling, or wheezing have been reported. Severe reactions like anaphylaxis are very rare, but if you have a known rice allergy, skip this product and talk with your doctor first.
Can I take this while pregnant or breastfeeding?
Rice bran is rated likely safe in pregnancy and lactation at normal food amounts. However, safety data on concentrated supplement doses is limited, so talk with your doctor or pharmacist before you start to make sure it's right for your situation.
Does it actually work for high cholesterol?
Rice bran is rated possibly effective for abnormal blood fat levels (dyslipidemia). That means some evidence supports it, but more research would help confirm how well it works in practice.
What's in this besides the active ingredients?
The inactive ingredients are microcrystalline cellulose, croscarmellose sodium, stearic acid, silica, magnesium stearate, hydroxypropyl methyl cellulose, and polyethylene glycol — these are fillers and binders that help hold the supplement together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Noxylane4 Double Strength is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Noxylane4 Double Strength label
Go deeper

The Full Monographs Behind Noxylane4 Double Strength’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Arabinoxylan

Interacts with 86 drugs

Arabinoxylan is a type of dietary fiber found in cereal grains that acts as a prebiotic and may modestly affect blood sugar and blood fats. The evidence for most uses is early and limited, s...

Read the full Arabinoxylan monograph → Herb & supplement monograph

Rice Bran

Rice bran is the nutrient-rich outer layer of the rice grain and is a good source of fiber, healthy fats, and plant compounds. It is most studied for helping lower cholesterol, but for most...

Read the full Rice Bran monograph →
Sources

Sources & How We Checked

Noxylane4 Double Strength's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Rice Bran 7 references
  1. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  2. Fujiwaki T, Furusho K. The effects of rice bran broth bathing in patients with atopic dermatitis. Acta Paediatr Jpn 1992;34:505-10.
  3. Uenotsuchi T, Satoh E, Kiryu H, Yano Y. Pyemotes dermatitis caused by indirect contact with husk rice. Br J Dermatol 2000;143:680-2. DOI
  4. Satoh R, Tsuge I, Tokuda R, Teshima R. Analysis of the distribution of rice allergens in brown rice grains and of the allergenicity of products containing rice bran. Food Chem. 2019;276:761-767. PubMed
  5. Togashi Y, Inomata N, Suzuki A, Hakuta A, Aihara M. Pediatric case with rice bran allergy induced by epicutaneous sensitization in a family rice shop. Allergol Int. 2019;68(1):117-118. PubMed
  6. So WKW, Chan JYW, Law BMH, et al. Effects of a Rice Bran Dietary Intervention on the Composition of the Intestinal Microbiota of Adults with a High Risk of Colorectal Cancer: A Pilot Randomised-Controlled Trial. Nutrients 2021;13(2):526. PubMed
  7. Haneda Y, Kadowaki S, Furui M, Taketani T. A pediatric case of food-dependent exercise-induced anaphylaxis due to rice bran. Asia Pac Allergy 2021;11(1):e4. PubMed

See these in context on the Rice Bran monograph →

Arabinoxylan 8 references
  1. Grasten S, Liukkonen K-H, Chrevatidis A, et al. Effects of wheat pentosan and inulin on the metabolic activity of fecal microbiota and on bowel function in healthy humans. Nutrition Res 2003;23:1503-14. DOI
  2. Lu ZX, Walker KZ, Muir JG, Mascara T, O'Dea K. Arabinoxylan fiber, a byproduct of wheat flour processing, reduces the postprandial glucose response in normoglycemic subjects. Am J Clin Nutr 2000;71(5):1123-1128.
  3. Lu ZX, Walker KZ, Muir JG, O'Dea K. Arabinoxylan fibre improves metabolic control in people with Type II diabetes. Eur J Clin Nutr 2004;58(4):621-8. PubMed
  4. Garcia AL, Otto B, Reich SC, et al. Arabinoxylan consumption decreases postprandial serum glucose, serum insulin and plasma total ghrelin response in subjects with impaired glucose tolerance. Eur J Clin Nutr 2007;61(3):334-41. PubMed
  5. Garcia AL, Steiniger J, Reich SC, et al. Arabinoxylan fibre consumption improved glucose metabolism, but did not affect serum adipokines in subjects with impaired glucose tolerance. Horm Metab Res 2006;38(11):761-766. PubMed
  6. François IE, Lescroart O, Veraverbeke WS, et al. Effects of a wheat bran extract containing arabinoxylan oligosaccharides on gastrointestinal health parameters in healthy adult human volunteers: a double-blind, randomised, placebo-controlled, cross-over t
  7. Schioldan AG, Gregersen S, Hald S, et al. Effects of a diet rich in arabinoxylan and resistant starch compared with a diet rich in refined carbohydrates on postprandial metabolism and features of the metabolic syndrome. Eur J Nutr. 2018 Mar;57(2):795-807. PubMed
  8. Scarpellini E, Deloose E, Vos R, et al, The effect of arabinoxylooligosaccharides on gastric sensory-motor function and nutrient tolerance in man. Neurogastroenterol Motil. 2016 Aug;28(8):1194-203. PubMed

See these in context on the Arabinoxylan monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team