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Dietary supplement

Noxylane4 Ingredients & Drug Interactions

by LaneInnovative

Noxylane4 label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Noxylane4 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Noxylane4 is a dietary supplement by LaneInnovative with 2 active ingredients. Its ingredients are commonly taken for blood sugar support, digestive and gut health (prebiotic), cholesterol and triglyceride support.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Arabinoxylane Compound Proprietary Blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Noxylane4 by LaneInnovative

Ask about any prescription or over-the-counter medication and we check it for interactions with Noxylane4 by LaneInnovative — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Noxylane4 by LaneInnovative

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 3 active ingredients.
  • “Arabinoxylane Compound Proprietary Blend” is a proprietary blend — the label gives one combined amount (1,000 mg) without saying how much of each component you get.

Noxylane4 has three active ingredients: rice bran, HAI Amino Acid Extract, an Arabinoxylane Compound Proprietary Blend, and Hyphomycetes mycelia enzyme. Rice bran is a grain byproduct that may help with cholesterol levels.

The other two active ingredients are part of a proprietary formula, so their specific roles aren't detailed in the product facts. The capsule also contains inactive ingredients — microcrystalline cellulose, croscarmellose sodium, stearic acid, silica, magnesium stearate, and gelatin — which serve as fillers and binders to hold the capsule together.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: immune defense.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

Rice bran in this product is possibly effective for dyslipidemia (abnormal cholesterol and triglyceride levels). It's considered possibly ineffective for colorectal cancer prevention, and there isn't enough reliable evidence to say whether it works for alopecia areata (patchy hair loss).

We don't have effectiveness data on file for HAI Amino Acid Extract, the Arabinoxylane Compound Proprietary Blend, or Hyphomycetes mycelia enzyme, so we can't say what those components are meant to do or whether they work.

The evidence, ingredient by ingredient Arabinoxylan Rice Bran

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Rice bran is likely safe during pregnancy and lactation. When taken by mouth, it's generally well tolerated, though increasing your bran intake can cause abdominal discomfort, bloating, and changes in bowel habits, especially in the first few weeks.

Allergic reactions are rare but can happen — they range from itching and hives to swelling and, in very rare cases, anaphylaxis (a severe, life-threatening reaction). Because concentrated rice bran supplements haven't been studied as thoroughly as food amounts, use caution and talk with your doctor if you have concerns.

We don't have safety data on file for HAI Amino Acid Extract or Hyphomycetes mycelia enzyme.

Side effects, ingredient by ingredient Arabinoxylan Rice Bran

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. However, we don't hold data for HAI Amino Acid Extract or Hyphomycetes mycelia enzyme, so ask your doctor or pharmacist to review those two ingredients against your current medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Noxylane4 may be worth considering if you're interested in cholesterol support and tolerate bran well — but start low and go slow to let your digestive system adjust. Skip it if you have a known rice allergy.

Since we can't check two of the four active ingredients for interactions, talk with your pharmacist before taking it alongside any medications you're on.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Noxylane4, straight from the product label.

Brand LaneInnovative
Barcode (UPC) 002110600200
Net contents 50 Capsule(s)
Market status On market
Date entered into DSLD Jul 23, 2020
DSLD ID 230671
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Noxylane4 by LaneInnovative, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
4 Capsule(s)
Servings per container
12
UPC/BARCODE
002110600200
IngredientAmount% DV
Calories5 Calorie(s)--
Total Carbohydrates1 Gram(s)1%
Rice Bran0 NP--
HAI Amino Acid Extract1 mg--
Arabinoxylane Compound Proprietary Blend1000 mg--
Hyphomycetes mycelia enzyme0 NP--

Other ingredients: Microcrystalline Cellulose, Croscarmellose Sodium, Stearic Acid, Silica, Magnesium Stearate, Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Noxylane4 is the next generation in immune defense from LaneInnovative.

This product contains no animal by-products.

HAI Potentiated Clinically shown to support NK Cell Activity

Formula

It contains Arabinoxylane - a rice bran hemicellulose modified by Shitake mushroom enzymes - and HAI. Heated Algal Ingredient (HAI) is an amino acid complex from Japanese seaweed that appears to enhance absorption.

(250 mg Arabinoxylane with HAI)

Suggested/Recommended/Usage/Directions

Suggested use for adult: Daily wellness: Take 2 to 4 capsules daily.

Storage

Store in a cool dry place.

Precautions

Keep out of reach of children.

Do not use if bottle seal is broken or missing.

Consult a health care professional first if you are pregnant or nursing.

General Statements

LaneInnovative Since 1994

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

GMP Good Manufacturing Practice Quality Product

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Noxylane4 by LaneInnovative label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Noxylane4 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Noxylane4 by LaneInnovative

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container12 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

HAI Amino Acid Extract

1 mg per serving Form: Sea Algae

Arabinoxylane Compound Proprietary Blend

Interacts with
86 drugs
1000 mg per serving

Arabinoxylan is a type of dietary fiber found in cereal grains that acts as a prebiotic and may modestly affect blood sugar and blood fats. The eviden...

Arabinoxylane Compound Proprietary Blend monograph & interactions
  • › Rice Bran
  • › Hyphomycetes mycelia enzyme

Other (inactive) ingredients: Microcrystalline Cellulose, Croscarmellose Sodium, Stearic Acid, Silica, Magnesium Stearate, Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Noxylane4 by LaneInnovative Drug Interactions

Want to check YOUR meds against Noxylane4?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Arabinoxylane Compound Proprietary Blend 86

Individual Drug Interactions

The ingredients in Noxylane4 interact with 86 drugs. Click any drug to see the details.

1 of the 2 ingredients in Noxylane4 interact with drugs. Each result below shows which ingredient is responsible. Arabinoxylane Compound Proprietary Blend

Each ingredient & the kinds of drugs it affects

For each ingredient in Noxylane4 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Arabinoxylane Compound Proprietary Blend1 drug type · 86 drugs

Antidiabetes Drugs

Evidence from human research suggests that an arabinoxylan-rich fiber can reduce postprandial glucose levels. Theoretically, arabinoxylan might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia. Monitor blood glucose levels closely. Dose adjustments might be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence B
Arabinoxylane Compound Proprietary Blend full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Noxylane4, from the product label.

LaneInnovative

See all LaneInnovative products
Name
LaneInnovative, Inc.
City
Vero Beach
State
FL
ZipCode
32964
Phone Number
1-800-526-3005
Web Address
www.laneinnovative.com
Pharmacist Counseling Corner

Noxylane4 by LaneInnovative: Common Questions

Does Noxylane4 by LaneInnovative interact with any medications?
Yes. Based on its ingredients, Noxylane4 has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Noxylane4 contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Noxylane4 if I'm pregnant or breastfeeding?
Rice bran, the main ingredient we have data on, is likely safe during pregnancy and lactation. We don't have pregnancy or breastfeeding information on file for the other active ingredients, so talk with your doctor or pharmacist to make sure it's right for your situation.
What are the most common side effects?
Rice bran can cause abdominal discomfort, bloating, and changes in bowel habits, especially when you first start taking it or increase the dose. These effects are usually mild and tend to settle down after a few weeks as your body adjusts.
Could I have an allergic reaction to this product?
Allergic reactions to rice bran are rare but can happen — symptoms range from itching and hives to swelling and, very rarely, a severe reaction. If you have a known rice allergy or have had allergic reactions to bran products before, avoid this supplement.
Does rice bran really help with cholesterol?
Rice bran is possibly effective for dyslipidemia — that means the evidence suggests it may help with cholesterol and triglyceride levels, but the research isn't definitive yet. Results may vary from person to person.
What is the Arabinoxylane Compound Proprietary Blend?
The product facts tell us it's part of the formula, but they don't break down what's in it or what it's supposed to do, since it's listed as a proprietary blend. Your best bet is to contact the manufacturer or check the label if you want more detail.
Are there any fillers or other ingredients I should know about?
Yes — the capsule contains microcrystalline cellulose, croscarmellose sodium, stearic acid, silica, magnesium stearate, and gelatin as inactive ingredients. These help hold the capsule together and aren't active components.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Noxylane4 label
Go deeper

The Full Monographs Behind Noxylane4’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Arabinoxylan

Interacts with 86 drugs

Arabinoxylan is a type of dietary fiber found in cereal grains that acts as a prebiotic and may modestly affect blood sugar and blood fats. The evidence for most uses is early and limited, s...

Read the full Arabinoxylan monograph → Herb & supplement monograph

Rice Bran

Rice bran is the nutrient-rich outer layer of the rice grain and is a good source of fiber, healthy fats, and plant compounds. It is most studied for helping lower cholesterol, but for most...

Read the full Rice Bran monograph →
Sources

Sources & How We Checked

Noxylane4's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Rice Bran 7 references
  1. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  2. Fujiwaki T, Furusho K. The effects of rice bran broth bathing in patients with atopic dermatitis. Acta Paediatr Jpn 1992;34:505-10.
  3. Uenotsuchi T, Satoh E, Kiryu H, Yano Y. Pyemotes dermatitis caused by indirect contact with husk rice. Br J Dermatol 2000;143:680-2. DOI
  4. Satoh R, Tsuge I, Tokuda R, Teshima R. Analysis of the distribution of rice allergens in brown rice grains and of the allergenicity of products containing rice bran. Food Chem. 2019;276:761-767. PubMed
  5. Togashi Y, Inomata N, Suzuki A, Hakuta A, Aihara M. Pediatric case with rice bran allergy induced by epicutaneous sensitization in a family rice shop. Allergol Int. 2019;68(1):117-118. PubMed
  6. So WKW, Chan JYW, Law BMH, et al. Effects of a Rice Bran Dietary Intervention on the Composition of the Intestinal Microbiota of Adults with a High Risk of Colorectal Cancer: A Pilot Randomised-Controlled Trial. Nutrients 2021;13(2):526. PubMed
  7. Haneda Y, Kadowaki S, Furui M, Taketani T. A pediatric case of food-dependent exercise-induced anaphylaxis due to rice bran. Asia Pac Allergy 2021;11(1):e4. PubMed

See these in context on the Rice Bran monograph →

Arabinoxylan 8 references
  1. Grasten S, Liukkonen K-H, Chrevatidis A, et al. Effects of wheat pentosan and inulin on the metabolic activity of fecal microbiota and on bowel function in healthy humans. Nutrition Res 2003;23:1503-14. DOI
  2. Lu ZX, Walker KZ, Muir JG, Mascara T, O'Dea K. Arabinoxylan fiber, a byproduct of wheat flour processing, reduces the postprandial glucose response in normoglycemic subjects. Am J Clin Nutr 2000;71(5):1123-1128.
  3. Lu ZX, Walker KZ, Muir JG, O'Dea K. Arabinoxylan fibre improves metabolic control in people with Type II diabetes. Eur J Clin Nutr 2004;58(4):621-8. PubMed
  4. Garcia AL, Otto B, Reich SC, et al. Arabinoxylan consumption decreases postprandial serum glucose, serum insulin and plasma total ghrelin response in subjects with impaired glucose tolerance. Eur J Clin Nutr 2007;61(3):334-41. PubMed
  5. Garcia AL, Steiniger J, Reich SC, et al. Arabinoxylan fibre consumption improved glucose metabolism, but did not affect serum adipokines in subjects with impaired glucose tolerance. Horm Metab Res 2006;38(11):761-766. PubMed
  6. François IE, Lescroart O, Veraverbeke WS, et al. Effects of a wheat bran extract containing arabinoxylan oligosaccharides on gastrointestinal health parameters in healthy adult human volunteers: a double-blind, randomised, placebo-controlled, cross-over t
  7. Schioldan AG, Gregersen S, Hald S, et al. Effects of a diet rich in arabinoxylan and resistant starch compared with a diet rich in refined carbohydrates on postprandial metabolism and features of the metabolic syndrome. Eur J Nutr. 2018 Mar;57(2):795-807. PubMed
  8. Scarpellini E, Deloose E, Vos R, et al, The effect of arabinoxylooligosaccharides on gastric sensory-motor function and nutrient tolerance in man. Neurogastroenterol Motil. 2016 Aug;28(8):1194-203. PubMed

See these in context on the Arabinoxylan monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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