Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

OmegaAstin Ingredients & Drug Interactions

by BioAstin

OmegaAstin label
See full label image
Softgel Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking OmegaAstin against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

OmegaAstin is a dietary supplement by BioAstin with 4 active ingredients. Its ingredients are commonly taken for vegan/vegetarian source of omega-3s (dha and epa), heart and triglyceride health, brain and eye support.Based on those ingredients, 978 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are natural Astaxanthin, Algal Oil, Flaxseed Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against OmegaAstin by BioAstin

Ask about any prescription or over-the-counter medication and we check it for interactions with OmegaAstin by BioAstin — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of OmegaAstin by BioAstin

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

BioAstin OmegaAstin is a softgel with 4 active ingredients. Algal oil supplies the omega-3 fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), which support heart and brain health.

Natural astaxanthin is a carotenoid (a plant pigment) from algae believed to have antioxidant properties. Flaxseed oil contributes alpha-linolenic acid (ALA), another omega-3 that may support inflammation and cholesterol.

Gamma-linolenic acid (GLA) is an omega-6 fatty acid. The softgel also contains inactive ingredients like modified cornstarch, carrageenan, glycerin, sorbitol, high oleic sunflower oil, soy lecithin, rosemary, tocopherols, ascorbyl palmitate, and purified water.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: support healthy cardiovascular system and brain function.
  • We looked for evidence on: Cardiovascular disease (CVD), Coronary heart disease (CHD), Heart failure, Hyperlipidemia, Hypertension, Atherosclerosis — and 4 related terms.
  • The closest evidence on file: Flaxseed Oil is rated "Possibly Ineffective" for Hyperlipidemia (Natural Medicines).
  • Also on file: Algal Oil is rated "Possibly Ineffective" for Cognitive function.
  • Also on file: Flaxseed Oil is rated "Insufficient Reliable Evidence To Rate" for Atherosclerosis, Cardiovascular disease (CVD), Cognitive function, Hypertension.

The evidence we hold on BioAstin's active ingredients is mixed and often limited. Algal oil shows possibly effective evidence for preterm labor prevention, but the data rates it possibly ineffective for fractures, cystic fibrosis, physical performance, and cognitive function — and there isn't enough reliable evidence to rate it for nonalcoholic fatty liver disease.

Astaxanthin's effectiveness for age-related cognitive decline, age-related macular degeneration, aging skin, Alzheimer disease, athletic performance, and carpal tunnel syndrome all lack sufficient reliable evidence. Flaxseed oil is rated possibly ineffective for obesity, rheumatoid arthritis, bipolar disorder, and high cholesterol (hyperlipidemia).

We hold no established effectiveness data for gamma-linolenic acid.

The evidence, ingredient by ingredient Algal Oil Astaxanthin Flaxseed Oil

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Algal oil is generally well tolerated by most healthy adults at typical supplement doses. One case of increased hair loss was reported in a child after completing DHA supplementation, though a direct link isn't clear, and theoretical concerns exist about itching, rash, or hand warmth — though these remain unconfirmed.

DHA may modestly raise LDL cholesterol (the "bad" kind) by about 8% in some people without heart disease, and observational research suggests a possible link between higher DHA intake and prostate cancer risk, though evidence remains unclear. For pregnancy, DHA is often recommended but use only under your doctor's guidance; during breastfeeding, talk to your provider first.

Astaxanthin is generally well tolerated in studies, but long-term safety data are limited — avoid it during pregnancy and breastfeeding due to insufficient safety information. Common side effects include abdominal pain, diarrhea, and red-colored stools; higher doses have caused severe stomach pain in rare cases.

Flaxseed oil is generally well tolerated, though a small number of people report changes in bowel habits, dry mouth, and upset stomach at 5 grams daily; high doses (30+ grams daily) may cause loose stools and diarrhea. Rare severe allergic reactions are possible.

Pregnancy data suggest it's possibly safe, but check with your doctor; breastfeeding safety information is limited.

Side effects, ingredient by ingredient Algal Oil Astaxanthin Flaxseed Oil

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Flaxseed Oil, Astaxanthin, Algal Oil.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 979 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking BioAstin OmegaAstin, check with your doctor or pharmacist if you take blood pressure medications (antihypertensive drugs) — both algal oil and flaxseed oil may lower pressure further. If you take blood thinners (anticoagulant or antiplatelet drugs), ezetimibe (Zetia), or antidiabetes drugs, those also interact and need verification.

Astaxanthin may theoretically reduce levels of medications broken down by your liver's CYP3A4 or CYP2B6 enzymes, though this hasn't been reported in humans — still worth confirming with your provider.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

BioAstin OmegaAstin is a multi-ingredient omega-3 supplement that may appeal to people looking for combined algal and flaxseed oils with astaxanthin. If you take blood pressure medications, blood thinners, diabetes drugs, or cholesterol medications — especially ezetimibe — you should check your exact medications with your doctor or pharmacist before starting, because this product carries documented interactions that could affect how your drugs work or your blood pressure.

Pregnant or breastfeeding individuals should discuss it with their provider first given the limited safety data for astaxanthin and the need for medical guidance on DHA use.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about OmegaAstin, straight from the product label.

Brand BioAstin
Barcode (UPC) 732894035140
Net contents 60 Vegan Softgel(s)
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 241925
Product type Other Combinations
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for OmegaAstin by BioAstin, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Vegan Softgel(s)
Maximum serving Sizes:
2 Vegan Softgel(s)
Servings per container
30
UPC/BARCODE
732894035140
IngredientAmount% DV
Calories11 Calorie(s)--
Calories from Fat9 Calorie(s)--
Total Fat1 Gram(s)2%
Algal Oil50 mg--
natural Astaxanthin8 mg--
Flaxseed Oil150 mg--
Gamma-Linolenic Acid70 mg--

Other ingredients: Non-GMO modified cornstarch, Carrageenan, Glycerin, Sorbitol, high Oleic Sunflower Oil, Soy Lecithin, Rosemary, Tocopherols, Ascorbyl Palmitate, purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Two soft gels per day with a meal.

Formula

OmegaAstin combines BioAstin Hawaiian Astaxanthin, one of nature's most powerful antioxidants, with naturally occurring omega-3 fatty acids found in flaxseed oil, DHA found in Algal oil, and GLA omega-6 fatty acids found in Evening primrose oil and borage oil.

Free of herbicides and pesticides, and made with Non-GMO Project Verified BioAstin Natural Astaxanthin.

8 mg heart formula Powered by super antioxidant BioAstin Hawaiian Astaxanthin

Astaxanthin Omegas 3-6

Formulation

Formulated by a team of medical doctors to support a healthy cardiovascular system and healthy brain function.

Free of gluten, lactose, and artificial colors. Free of herbicides and pesticides, and made with Non-GMO Project Verified BioAstin Natural Astaxanthin.

Supports brain and heart health naturally

Certified Vegan vegan.org

Glyphosate Residue Free detoxproject.org

Precautions

Contains soy.

Consult your healthcare practitioner before use if you are pregnant or nursing.

Do not use if outer seal is broken.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Made with Aloha.

Brand IP Statement(s)

2019 Nutrex Hawaii

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Certified Vegan vegan.org Igen Non-GMO Tested GF Certified Gluten-free Glyphosate Residue Free detoxproject.org

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

OmegaAstin by BioAstin label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

OmegaAstin label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in OmegaAstin by BioAstin

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Vegan Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Algal Oil

Interacts with
375 drugs
50 mg per serving Form: Schizochytrium sp.

Algal oil is a plant-based source of the omega-3 fats DHA and (in some products) EPA, making it a popular alternative to fish oil for vegetarians, veg...

Algal Oil monograph & interactions

Natural Astaxanthin

Interacts with
671 drugs
8 mg per serving Form: Haematococcus pluvialis

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

Natural Astaxanthin monograph & interactions

Flaxseed Oil

Interacts with
293 drugs
150 mg per serving Form: Linum usitatissimum

Flaxseed oil is a plant-based source of the omega-3 fatty acid ALA, which the body can partly convert to the omega-3s found in fish oil. It may help s...

Flaxseed Oil monograph & interactions

Gamma-Linolenic Acid

70 mg per serving Form: Borage Oil, Evening Primrose Oil

Other (inactive) ingredients: Non-GMO modified cornstarch, Carrageenan, Glycerin, Sorbitol, High Oleic Sunflower Oil, Soy Lecithin, Rosemary, Tocopherols, Ascorbyl Palmitate, Purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

OmegaAstin by BioAstin Drug Interactions

Want to check YOUR meds against OmegaAstin?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
978Drugs
978 Moderate

Ingredients driving the most interactions

natural Astaxanthin 671
Algal Oil 375
Flaxseed Oil 293

Individual Drug Interactions

The ingredients in OmegaAstin interact with 978 drugs. Click any drug to see the details.

3 of the 4 ingredients in OmegaAstin interact with drugs. Each result below shows which ingredient is responsible. natural Astaxanthin Algal Oil Flaxseed Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in OmegaAstin with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

natural Astaxanthin2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
natural Astaxanthin full monograph & interactions

Algal Oil3 drug types · 375 drugs

Antidiabetes Drugs

Theoretically, taking algal oil with antidiabetes drugs might interfere with the effects of antidiabetes drugs and reduce their effects.
Most algal oil contains docosahexaenoic acid (DHA). Clinical research in people with type 2 diabetes, including those taking antidiabetes drugs, shows that taking DHA 4 grams daily for 6 weeks increases fasting blood glucose levels by about 18 mg/dL when compared with taking olive oil.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Algal oil usually contains docosahexaenoic acid (DHA) and/or eicosapentaenoic acid (EPA). There is evidence that fish oil, which also contains DHA and EPA, can modestly lower blood pressure and might have additive effects in patients treated with antihypertensive drugs.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, algal oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
The risk of interaction is highest for algal oil containing high amounts (> 2 grams daily) of eicosapentaenoic acid (EPA), or EPA and docosahexaenoic acid (DHA). High doses of EPA or oils containing EPA and DHA can reduce platelet aggregation in humans. However, most algal oil contains very little EPA and larger amounts of DHA. While some conflicting evidence exist, most research shows that DHA alone does not affect blood clotting.

Likelihood Unlikely Evidence D
Algal Oil full monograph & interactions

Flaxseed Oil3 drug types · 293 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Small clinical studies show that consuming flaxseed oil might decrease platelet aggregation and increase bleeding time.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Some clinical evidence suggests that long-term consumption of flaxseed oil can modestly lower systolic and diastolic blood pressure, while other clinical research shows no effect.

Likelihood Possible Evidence D
Ezetimibe (Zetia)

Concomitant use of flaxseed oil and ezetimibe reduces the absorption of alpha-linolenic acid from flaxseed oil.
In one clinical study, concomitant consumption of ezetimibe 10 mg daily with flaxseed oil 2 grams providing 1 gram of alpha-linolenic acid daily blocked the absorption of alpha-linolenic acid, resulting in an overall reduction in alpha-linolenic plasma levels from baseline.

Likelihood Probable Evidence B
Flaxseed Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for OmegaAstin, from the product label.

BioAstin

See all BioAstin products
Name
Nutrex Hawaii Inc
City
Kailua-Kona
State
HI
ZipCode
96740
Phone Number
1-800-453-1187
Web Address
www.nutrex-hawaii.com
Pharmacist Counseling Corner

OmegaAstin by BioAstin: Common Questions

Does OmegaAstin by BioAstin interact with any medications?
Yes. Based on its ingredients, OmegaAstin has a known interaction with 978 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
OmegaAstin contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is astaxanthin safe during pregnancy?
No — there isn't enough safety data for astaxanthin in pregnancy, so the data advises against it. The algal oil in this product does contain DHA, which is often recommended in pregnancy, but use it only under your doctor's guidance.
Can I take this if I'm breastfeeding?
Astaxanthin should be avoided while breastfeeding because safety data are insufficient. The DHA from algal oil does support infant development, but talk to your provider before using this product while nursing.
What are the most common side effects?
Astaxanthin most commonly causes abdominal pain, diarrhea, and red-colored stools. Flaxseed oil at typical doses is well tolerated, though a small number of people report bowel changes, dry mouth, or upset stomach. Very high doses of flaxseed oil may cause loose stools.
Does this product actually work for anything?
Algal oil shows possibly effective evidence for preventing preterm labor, but the evidence for other claims — cognitive function, fractures, athletic performance — rates it possibly ineffective or insufficient. Flaxseed oil is rated possibly ineffective for obesity, arthritis, bipolar disorder, and high cholesterol. Astaxanthin's effectiveness isn't well established in our data.
Will this raise my cholesterol?
Algal oil's DHA may modestly raise LDL cholesterol (about 8%) in some people without existing heart disease. Flaxseed oil is rated possibly ineffective for high cholesterol in the evidence we hold. If you have cholesterol concerns, discuss this product with your doctor.
Can this interfere with my cholesterol medication ezetimibe (Zetia)?
Yes — ezetimibe blocks the absorption of flaxseed oil's alpha-linolenic acid, reducing the product's effect. Check with your doctor or pharmacist before combining them.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

OmegaAstin label
Go deeper

The Full Monographs Behind OmegaAstin’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Algal Oil

Interacts with 375 drugs

Algal oil is a plant-based source of the omega-3 fats DHA and (in some products) EPA, making it a popular alternative to fish oil for vegetarians, vegans, and people who dislike fish. There...

Read the full Algal Oil monograph → Herb & supplement monograph

Astaxanthin

Interacts with 671 drugs

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...

Read the full Astaxanthin monograph → Herb & supplement monograph

Flaxseed Oil

Interacts with 293 drugs

Flaxseed oil is a plant-based source of the omega-3 fatty acid ALA, which the body can partly convert to the omega-3s found in fish oil. It may help support heart health and provide healthy...

Read the full Flaxseed Oil monograph →
Sources

Sources & How We Checked

OmegaAstin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 67 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Algal Oil 43 references
  1. Prisco D, Paniccia R, Bandinelli B, et al. Effect of medium-term supplementation with a moderate dose of n-3 polyunsaturated fatty acids on blood pressure in mild hypertensive patients. Thromb Res 1998;1:105-12.
  2. Grimsgaard S, Bonaa KH, Hansen JB, Nordoy A. Highly purified eicosapentaenoic acid and docosahexaenoic acid in humans have similar triacylglycerol-lowering effects but divergent effects on serum fatty acids. Am J Clin Nutr 1997;66:649-59.
  3. Toft I, Bonaa KH, Ingebretsen OC, et al. Effects of n-3 polyunsaturated fatty acids on glucose homeostasis and blood pressure in essential hypertension. A randomized, controlled trial. Ann Intern Med 1995;123:911-8.
  4. Sacks FM, Hebert P, Appel LJ, et al. Short report: the effect of fish oil on blood pressure and high-density lipoprotein-cholesterol levels in phase I of the trials of hypertension prevention. J Hypertens 1994;12:209-13.
  5. Vandongen R, Mori TA, Burke V, et al. Effects on blood pressure of omega 3 fats in subjects at increased risk of cardiovascular disease. Hypertension 1993;22:371-9. PubMed
  6. FDA. Center for Food Safety and Applied Nutrition. Letter regarding dietary supplement health claim for omega-3 fatty acids and coronary heart disease. Available at: http://www.fda.gov/ohrms/dockets/dockets/95s0316/95s-0316-Rpt0272-38-Appendix-D-Reference
  7. Leaf A. On the reanalysis of the GISSI-Prevenzione. Circulation 2002;105:1874-5. PubMed
  8. Connor WE. n-3 Fatty acids from fish and fish oil: panacea or nostrum? Am J Clin Nutr 2001;74;415-6. PubMed
  9. Calder PC. N-3 polyunsaturated fatty acids, inflammation and immunity: pouring oil on troubled waters or another fishy tale? Nutr Res 2001;21:309-41. DOI
  10. Pedersen HS, Mulvad G, Seidelin KN, et al. N-3 fatty acids as a risk factor for haemorrhagic stroke. Lancet 1999;353:812-3. PubMed
  11. Terano T, Hirai A, Hamazaki T, et al. Effect of oral administration of highly purified eicosapentaenoic acid on platelet function, blood viscosity and red cell deformability in healthy human subjects. Atherosclerosis 1983;46:321-31.. PubMed
  12. Kris-Ehterton PM, Harris WS, Appel LJ, et al. Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation 2002;106:2747-57. PubMed
  13. Woodman RJ, Mori TA, Burke V, et al. Effects of purified eicosapentaenoic and docosahexaenoic acids on glycemic control, blood pressure, and serum lipids in type 2 diabetic patients with treated hypertension. Am J Clin Nutr 2002;76:1007-15.. PubMed
  14. Marangell LB, Martinez JM, Zboyan HA, et al. A double-blind, placebo-controlled study of the omega-3 fatty acid docosahexaenoic acid in the treatment of major depression. Am J Psychiatry 2003;160:996-8.. PubMed
  15. Leng GC, Smith FB, Fowkes FG, et al. Relationship between plasma essential fatty acids and smoking, serum lipids, blood pressure and haemostatic and rheological factors. Prostaglandins Leukot Essent Fatty Acids 1994;51:101-8. PubMed
  16. Nelson GJ, Schmidt PS, Bartolini GL, et al. The effect of dietary docosahexaenoic acid on platelet function, platelet fatty acid composition, and blood coagulation in humans. Lipids 1997;32:1129-36. PubMed
  17. Wheaton DH, Hoffman DR, Locke KG, et al. Biological safety assessment of docosahexaenoic acid supplementation in a randomized clinical trial for X-linked retinitis pigmentosa. Arch Ophthalmol 2003;121:1269-78. PubMed
  18. Svaneborg N, Kristensen SD, Hansen LM, et al. The acute and short-time effect of supplementation with the combination of n-3 fatty acids and acetylsalicylic acid on platelet function and plasma lipids. Thromb Res 2002;105:311-6. PubMed
  19. Yokoyama M, Origasa H, Matsuzaki M, et al. Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis. Lancet 2007;369:1090-8. PubMed
  20. von Houwelingen R, Nordøy A, van der Beek E, et al. Effect of a moderate fish intake on blood pressure, bleeding time, hematology, and clinical chemistry in healthy males. Am J Clin Nutr. 1987 Sep;46(3):424-36. PubMed
  21. Goodnight SH Jr, Harris WS, Connor WE. The effects of dietary omega 3 fatty acids on platelet composition and function in man: a prospective, controlled study. Blood. 1981 Nov;58(5):880-5. DOI
  22. Mori, T. A., Bao, D. Q., Burke, V., Puddey, I. B., and Beilin, L. J. Docosahexaenoic acid but not eicosapentaenoic acid lowers ambulatory blood pressure and heart rate in humans. Hypertension 1999;34(2):253-260. PubMed
  23. Nestel, P., Shige, H., Pomeroy, S., Cehun, M., Abbey, M., and Raederstorff, D. The n-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid increase systemic arterial compliance in humans. Am.J.Clin.Nutr. 2002;76(2):326-330. PubMed
  24. Woodman, R. J., Mori, T. A., Burke, V., Puddey, I. B., Barden, A., Watts, G. F., and Beilin, L. J. Effects of purified eicosapentaenoic acid and docosahexaenoic acid on platelet, fibrinolytic and vascular function in hypertensive type 2 diabetic patients PubMed
  25. Theobald, H. E., Goodall, A. H., Sattar, N., Talbot, D. C., Chowienczyk, P. J., and Sanders, T. A. Low-dose docosahexaenoic acid lowers diastolic blood pressure in middle-aged men and women. J Nutr 2007;137(4):973-978.
  26. Mischoulon D, Best-Popescu C, Laposata M, et al. A double-blind dose-finding pilot study of docosahexaenoic acid (DHA) for major depressive disorder. Eur Neuropsychopharmacol. 2008;18(9):639-645. PubMed
  27. Arterburn, L. M., Oken, H. A., Bailey, Hall E., Hamersley, J., Kuratko, C. N., and Hoffman, J. P. Algal-oil capsules and cooked salmon: nutritionally equivalent sources of docosahexaenoic acid. J Am Diet Assoc 2008;108(7):1204-1209. PubMed
  28. Zucker, M. L., Bilyeu, D. S., Helmkamp, G. M., Harris, W. S., and Dujovne, C. A. Effects of dietary fish oil on platelet function and plasma lipids in hyperlipoproteinemic and normal subjects. Atherosclerosis 1988;73(1):13-22. PubMed
  29. Bernstein AM, Ding EL, Willett WC, Rimm EB. A meta-analysis shows that docosahexaenoic acid from algal oil reduces serum triglycerides and increases HDL-cholesterol and LDL-cholesterol in persons without coronary heart disease. J Nutr. 2012;142(1):99-104.
  30. Carlson SE, Colombo J, Gajewski BJ, Gustafson KM, Mundy D, Yeast J, Georgieff MK, Markley LA, Kerling EH, Shaddy DJ. DHA supplementation and pregnancy outcomes. Am J Clin Nutr. 2013 Apr;97(4):808-15. PubMed
  31. Fu YQ, Zheng JS, Yang B, Li D. Effect of individual omega-3 fatty acids on the risk of prostate cancer: a systematic review and dose-response meta-analysis of prospective cohort studies. J Epidemiol. 2015;25(4):261-74. PubMed
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Astaxanthin 3 references
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See these in context on the Astaxanthin monograph →

Flaxseed Oil 21 references
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  21. Mahmudiono T, Jasim SA, Karim YS, et al. The effect of flaxseed oil consumption on blood pressure among patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized clinical trials. Phytother Res 2022;36(10):

See these in context on the Flaxseed Oil monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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