Organic Aloe Vera Powder Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Organic Aloe Vera Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Organic Aloe Vera Powder is a dietary supplement by Nova Nutritions with 1 active ingredient. Its ingredients are commonly taken for minor burns and skin irritation, wound healing, constipation.Based on those ingredients, 461 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are certified organic Aloe vera powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Organic Aloe Vera Powder by Nova Nutritions
Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Aloe Vera Powder by Nova Nutritions — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Organic Aloe Vera Powder by Nova Nutritions
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: certified organic aloe vera powder. Aloe vera is a succulent plant gel that's been used traditionally for skin health, digestive support, and general wellness.
The powder form allows you to mix it into drinks or food. There are no other inactive ingredients listed.
Does it work?
Moderate evidence
The evidence we hold shows aloe vera powder is possibly effective for several uses: acne, obesity, diabetes, psoriasis, burns, and constipation. That means there's some clinical research suggesting benefit, but the evidence isn't yet strong or complete enough to call it proven.
If you're considering it for one of these purposes, talk with your doctor about whether it makes sense for you alongside any other treatments you're using.
How safe is it?
Well-documented data
Topical aloe gel is generally well tolerated in typical doses. Oral aloe latex — which is the part in this powder — carries more risk, especially at high doses or over the long term.
The most common side effects from taking it by mouth are belly pain, cramps, and diarrhea. Long-term use or overuse can cause more serious problems like severe potassium loss, muscle weakness, and irregular heartbeat.
The safety data advises against taking oral aloe during pregnancy because the latex can stimulate the uterus and act as a strong laxative. It's also not recommended while breastfeeding due to limited safety data and laxative effects.
If you're pregnant, nursing, or planning either, talk with your doctor or pharmacist before using this product.
Meds to double-check
Major interaction found
Before taking this product, double-check with your doctor or pharmacist if you take digoxin (a heart medication) — the interaction is Major. Also confirm your use if you're on blood thinners like warfarin or aspirin, diabetes medications, water pills (diuretics), other laxatives, or any drugs processed through the liver enzyme CYP1A2.
No interactions are documented with the inactive ingredients.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.
This powder may be worth considering if you're interested in aloe for acne, burns, constipation, or other uses on that list — but only if you don't take heart medications, blood thinners, diabetes drugs, water pills, or certain other prescription medications. Because aloe interacts with so many drugs and some interactions are serious, check your full medication list with your doctor or pharmacist before you start.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Organic Aloe Vera Powder, straight from the product label.
| Brand | Nova Nutritions |
|---|---|
| Barcode (UPC) | 732363273059 |
| Net contents | 16 Ounce(s); 454 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Aug 23, 2021 |
| DSLD ID | 252857 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Organic, Halal |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Organic Aloe Vera Powder by Nova Nutritions, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| certified organic Aloe vera powder | 2 Gram(s) | -- |
Other ingredients: None
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols
GMP Good Manufacturing Practice Product
100% Vegan Vegan USDA Organic
KLBD (Kosher)
Halal India www.Halalindia.com
Formulation
100% Vegan Vegan
USDA Organic
Gluten Free
100% Natural Raw
Product of India
Discontinue use and consult your doctor if any adverse reactions occur.
(AN ISO 9001:2015, GMP Certified Company) Mfg. Lic. Number: GA/713-A
Certified Organic by OneCert, Accreditation Number: NPOP/NAB/008
OneCert Certified Organic
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested Use: Mix 1/2 teaspoon with warm water, once or twice daily or as directed by a healthcare professional. It can be used for cooking and seasoning. Close the container tightly after each use.
Precautions
Keep out of reach of children.
Do not use if safety seal is broken or missing
Caution: For adults only, if you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.
Storage
Keep in cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formula
KLBD (Kosher)
Halal India www.Halalindia.com
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Organic Aloe Vera Powder by Nova Nutritions label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Organic Aloe Vera Powder by Nova Nutritions
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Gram(s) Dosage formPowder Servings per container227 Amounts shown are per serving.
Certified organic Aloe vera powder
Interacts with461 drugs
Aloe vera gel is widely used on the skin for minor burns and irritation, and some research suggests it may help. Aloe latex (the yellow part) is a str...
Certified organic Aloe vera powder monograph & interactionsOther (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.
Organic Aloe Vera Powder by Nova Nutritions Drug Interactions
HelloPharmacist Interaction Report
Nova Nutritions' Organic Aloe Vera Powder does interact with medications, and some of those interactions are serious.
The main concern is through aloe's interaction with digoxin (a heart medication), which carries a Major severity rating — aloe latex can deplete potassium and raise the risk of digoxin toxicity, especially with overuse.
Read the full breakdown — every affected drug type, severity by severity
Aloe also has Moderate interactions with blood thinners (anticoagulants and antiplatelet drugs) like warfarin and aspirin, raising bleeding risk. It may lower blood sugar levels, so it can add to the effects of diabetes medications and increase the risk of low blood sugar (hypoglycemia).
Aloe latex can also compound potassium loss when used with water pills (diuretics), and it may interfere with other stimulant laxatives by worsening fluid and electrolyte loss.
There's also a Minor interaction with a group of medications processed through a liver enzyme called CYP1A2 — aloe may reduce how well those drugs work. Altogether, these interactions span 461 individual medications.
Before you start this product, use the medication checker on this page to confirm your exact prescriptions, and talk with your doctor or pharmacist if you take any of these drug types.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Organic Aloe Vera Powder?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Organic Aloe Vera Powder interact with 461 drugs. Click any drug to see the details.
1 of the 1 ingredient in Organic Aloe Vera Powder interact with drugs. Each result below shows which ingredient is responsible. certified organic Aloe vera powder
DigoxinDigitek, Lanoxicaps, Lanoxin
How Digoxin interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderDigoxin (lanoxin) Major
Interaction Summary
Theoretically, aloe latex might increase the risk of adverse effects when taken with cardiac glycosides.
Read the full Certified Organic Aloe Vera Powder + Digoxin interactionAbciximabReoPro
How Abciximab interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Certified Organic Aloe Vera Powder + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Certified Organic Aloe Vera Powder + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Certified Organic Aloe Vera Powder + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Certified Organic Aloe Vera Powder + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Certified Organic Aloe Vera Powder + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Certified Organic Aloe Vera Powder + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderCytochrome P450 1a2 (cyp1a2) Substrates, Diuretic Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Certified Organic Aloe Vera Powder + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Certified Organic Aloe Vera Powder + Acetaminophen, Ibuprofen interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderCytochrome P450 1a2 (cyp1a2) Substrates, Diuretic Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Certified Organic Aloe Vera Powder + Acetaminophen, Pamabrom, Pyrilamine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Certified Organic Aloe Vera Powder + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Certified Organic Aloe Vera Powder + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Certified Organic Aloe Vera Powder + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Certified Organic Aloe Vera Powder + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Certified Organic Aloe Vera Powder + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Certified Organic Aloe Vera Powder + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Certified Organic Aloe Vera Powder + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Certified Organic Aloe Vera Powder + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Certified Organic Aloe Vera Powder + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Certified Organic Aloe Vera Powder + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Certified Organic Aloe Vera Powder + Amiloride, Hydrochlorothiazide interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Certified Organic Aloe Vera Powder + Ammonium Chloride interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Certified Organic Aloe Vera Powder + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Certified Organic Aloe Vera Powder + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Certified Organic Aloe Vera Powder + Anisindione interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Certified Organic Aloe Vera Powder + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Certified Organic Aloe Vera Powder + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Certified Organic Aloe Vera Powder + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Certified Organic Aloe Vera Powder + Argatroban interactionArmodafinilNuvigil
How Armodafinil interacts with Organic Aloe Vera Powder — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Aloe Vera PowderStimulant Laxatives Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Read the full Certified Organic Aloe Vera Powder + Armodafinil interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Organic Aloe Vera Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
certified organic Aloe vera powder
Digoxin (Lanoxin)
Theoretically, aloe latex might increase the risk of adverse effects when taken with cardiac glycosides.
Overuse of aloe latex can increase the risk of adverse effects from cardiac glycoside drugs, such as digoxin, due to potassium depletion. Overuse of aloe, along with cardiac glycoside drugs, can increase the risk of toxicity.
Anticoagulant/Antiplatelet Drugs
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aloe gel can inhibit platelet aggregation. This inhibition was greater than that seen with celecoxib, but less than that seen with aspirin.
Antidiabetes Drugs
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Preliminary clinical research suggests aloe gel might lower blood glucose levels and have additive effects when used with antidiabetes drugs. Monitor blood glucose levels closely.
Diuretic Drugs
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Overuse of aloe latex might compound diuretic-induced potassium loss, increasing the risk of hypokalemia.
Stimulant Laxatives
Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Due to cathartic laxative effects of aloe latex, concomitant use with other stimulant laxatives might compound fluid and electrolyte loss.
Warfarin (Coumadin)
Theoretically, aloe latex might increase the risk of bleeding when taken with warfarin.
Aloe latex has stimulant laxative effects. In some people aloe latex can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of aloe vera.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that aloe extract induces CYP1A2 enzymes.
Brand information
Manufacturer and brand details for Organic Aloe Vera Powder, from the product label.
Nova Nutritions
See all Nova Nutritions products- Name
- Nova Nutritions
- City
- Scotch Plains
- State
- New Jersey
- ZipCode
- 07076
- Web Address
- www.novanutritions.com
Organic Aloe Vera Powder by Nova Nutritions: Common Questions
Does Organic Aloe Vera Powder by Nova Nutritions interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does aloe vera powder actually work?
Can I take this if I'm pregnant or breastfeeding?
What are the side effects of taking aloe vera powder by mouth?
Why does aloe interact with so many medications?
Is this powder the same as aloe gel?
Can I take this long-term?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Organic Aloe Vera Powder is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Organic Aloe Vera Powder’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Organic Aloe Vera Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 41 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Aloe 41 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Nusko G, Schneider B, Schneider I, et al. Anthranoid laxative use is not a risk factor for colorectal neoplasia: results of a prospective case control study. Gut 2000;46:651-5. PubMed
- Luyckx VA, Ballantine R, Claeys M, et al. Herbal remedy-associated acute renal failure secondary to Cape aloes. Am J Kidney Dis 2002;39:E13. PubMed
- Rajasekaran S, Sivagnanam K, Ravi K, Subramanian S. Hypoglycemic effect of Aloe vera gel on streptozotocin-induced diabetes in experimental rats. J Med Food 2004;7:61-6.
- Williams MS, Burk M, Loprinzi CL, et al. Phase III double-blind evaluation of an aloe vera gel as a prophylactic agent for radiation-induced skin toxicity. Int J Radiat Oncol Biol Phys 1996;36:345-9. PubMed
- Vogler BK, Ernst E. Aloe vera: a systematic review of its clinical effectiveness. Br J Gen Pract 1999;49:823-8.
- Bottenberg MM, Wall GC, Harvey RL, Habib S. Oral aloe vera-induced hepatitis. Ann Pharmacother 2007;41:1740-3. PubMed
- Rabe C, Musch A, Schirmacher P, et al. Acute hepatitis induced by an Aloe vera preparation: a case report. World J Gastroenterol 2005;11:303-4. PubMed
- Kanat O, Ozet A, Ataergin S. Aloe vera-induced acute toxic hepatitis in a healthy young man. Eur J Int Med 2006;17:589. PubMed
- Mueller SO, Stopper H. Characterization of the genotoxicity of anthraquinones in mammalian cells. Biochim Biophys Acta 1999;1428:406-14. PubMed
- Schorkhuber M, Richter M, Dutter A, et al. Effect of anthraquinone laxatives on the proliferation and urokinase secretion of normal, premalignant and malignant colonic epithelial cells. Eur J Cancer 1998;34:1091-8. PubMed
- Yang HN, Kim DJ, Kim YM, et al. Aloe-induced toxic hepatitis. J Korean Med Sci 2010;25:492-5. PubMed
- Choonhakarn C, Busaracome P, Sripanidkulchai B, et al. A prospective, randomized clinical trial comparing topical aloe vera with 0.1% triamcinolone acetonide in mild to moderate plaque psoriasis. J.Eur.Acad.Dermatol.Venereol. 2010;24:168-72. PubMed
- Ishii Y, Tanizawa H, Takino Y. Studies of aloe. IV. Mechanism of cathartic effect. (3). Biol Pharm Bull. 1994;17:495-7. PubMed
- Ishii Y, Tanizawa H, Takino Y. Studies of aloe. V. Mechanism of cathartic effect. (4). Biol Pharm Bull. 1994;17:651-3. PubMed
- Nelemans FA. Clinical and toxicological aspects of anthraquinone laxatives. Pharmacology. 1976;14 Suppl 1:73-7. PubMed
- Paulsen E, Korsholm L, Brandrup F. A double-blind, placebo-controlled study of a commercial Aloe vera gel in the treatment of slight to moderate psoriasis vulgaris. J Eur Acad Dermatol Venereol. 2005;19:326-31.
- Huseini HF, Kianbakht S, Hajiaghaee R, et al. Anti-hyperglycemic and anti-hypercholesterolemic effects of Aloe vera leaf gel in hyperlipidemic type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial. Planta Med. 2012;78:311-6
- Ferreira, M., Teixeira, M., Silva, E., and Selores, M. Allergic contact dermatitis to Aloe vera. Contact Dermatitis 2007;57(4):278-279.
- Choonhakarn, C., Busaracome, P., Sripanidkulchai, B., and Sarakarn, P. The efficacy of aloe vera gel in the treatment of oral lichen planus: a randomized controlled trial. Br J Dermatol 2008;158(3):573-577. PubMed
- Baretta, Z., Ghiotto, C., Marino, D., and Jirillo, A. Aloe-induced hypokalemia in a patient with breast cancer during chemotherapy. Ann.Oncol. 2009;20(8):1445-1446. PubMed
- Hunter, D. and Frumkin, A. Adverse reactions to vitamin E and aloe vera preparations after dermabrasion and chemical peel. Cutis 1991;47(3):193-196.
- Alvarez-Perea, A., Garcia, A. P., Hernandez, A. L., de, Barrio M., and Baeza, M. L. Urticaria due to aloe vera: a new sensitizer? Ann.Allergy Asthma Immunol. 2010;105(5):404-405. PubMed
- Hogan, D. J. Widespread dermatitis after topical treatment of chronic leg ulcers and stasis dermatitis. CMAJ. 2-15-1988;138(4):336-338.
- Savchak VI. Acute bullous allergic dermatitis due to local application of aloe leaves. Vestnik Dermatologii i Venerologii 1977;12:44-45.
- Nakamura, T. and Kotajima, S. Contact dermatitis from aloe arborescens. Contact Dermatitis 1984;11(1):51. PubMed
- Shoji, A. Contact dermatitis to Aloe arborescens. Contact Dermatitis 1982;8(3):164-167. PubMed
- Morrow, D. M., Rapaport, M. J., and Strick, R. A. Hypersensitivity to aloe. Arch Dermatol. 1980;116(9):1064-1065. DOI
- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of AloeAndongensis Extract, Aloe Andongensis Leaf Juice,aloe Arborescens Leaf Extract, Aloe Arborescens Leaf Juice, Aloe Arborescens Leaf Protoplasts, Aloe Barbadensis Flower E
- Bhalang K, Thunyakitpisal P, Rungsirisatean N. Acemannan, a polysaccharide extracted from Aloe vera, is effective in the treatment of oral aphthous ulceration. J Altern Complement Med 2013;19(5):429-34.
- Hajheydari Z, Saeedi M, Morteza-Semnani K, Soltani A. Effect of Aloe vera topical gel combined with tretinoin in treatment of mild and moderate acne vulgaris: a randomized, double-blind, prospective trial. J Dermatolog Treat 2014;25(2):123-9.
- Jiménez-Encarnación E, Ríos G, Muñoz-Mirabal A, Vilá LM. Euforia-induced acute hepatitis in a patient with scleroderma. BMJ Case Rep 2012;2012. PubMed
- Lee J, Lee MS, Nam KW. Acute toxic hepatitis caused by an aloe vera preparation in a young patient: a case report with a literature review. Korean J Gastroenterol 2014;64(1):54-8. PubMed
- Guo X, Mei N. Aloe Vera - A Review of Toxicity and Adverse Clinical Effects. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 2016;34(2):77-96.
- Hoogenboom TCH, Patel N, Cook NA, Williams R, Taylor-Robinson SD, Lim AKP. The effect of Aloe vera juice on liver enzymes and hepatic structure in a healthy population. Integr Med (Encinitas) 2020;19(3):30-4.
- Mushtaq S, Mushtaq Z, Sarfraz J, et al. Comparison of effect of aloe vera gel with aspirin and celecoxib on platelet aggregation. Professional Med J. 2020; 27(5):973-978. DOI
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
- Sabbaghzadegan S, Soltani MH, Kamalinejad M, Bahrami M, Kabir A, Dadmehr M. The effect of a standardized capsule of Aloe vera gel on the quality of life in patients with systolic heart failure: A randomized double-blind placebo-controlled clinical trial.
- Lewis ED, Crowley DC, Guthrie N, Evans M. Healthy adults supplemented with a nutraceutical formulation containing Aloe vera gel, rosemary and Poria cocos enhances the effect of influenza vaccination in a randomized, triple-blind, placebo-controlled trial. PubMed
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