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Dietary supplement

D-Ribose 700 mg Ingredients & Drug Interactions

by Nova Nutritions

D-Ribose 700 mg label
See full label image
Capsule Category: Fiber And Other Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking D-Ribose 700 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

D-Ribose 700 mg is a dietary supplement by Nova Nutritions with 1 active ingredient. Its ingredients are commonly taken for energy and fatigue, athletic performance and recovery, fibromyalgia symptoms.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are D-Ribose, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against D-Ribose 700 mg by Nova Nutritions

Ask about any prescription or over-the-counter medication and we check it for interactions with D-Ribose 700 mg by Nova Nutritions — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of D-Ribose 700 mg by Nova Nutritions

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: D-Ribose powder, 700 mg per capsule. D-Ribose is a five-carbon sugar (pentose) that your cells use to make energy.

The capsule also contains inactive ingredients — cellulose, silicon dioxide, microcrystalline cellulose, and magnesium stearate — which are standard fillers and binders.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Ribose's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: promotes energy production and cardiovascular function.
  • We looked for evidence on: Athletic performance, Chronic fatigue syndrome (CFS), Congestive heart failure (CHF), Coronary artery bypass graft (CABG) surgery, Coronary heart disease (CHD), Fibromyalgia — and 4 related terms.
  • The closest evidence on file: Ribose is rated "Possibly Ineffective" for Athletic performance (Natural Medicines).
  • Also on file: Ribose is rated "Possibly Ineffective" for McArdle disease.
  • Also on file: Ribose is rated "Insufficient Reliable Evidence To Rate" for Coronary heart disease (CHD), Chronic fatigue syndrome (CFS), Congestive heart failure (CHF), Fibromyalgia, and more.

The evidence on D-Ribose is mixed and limited. For athletic performance and McArdle disease (a genetic muscle disorder), the available evidence suggests it is possibly ineffective.

For restless legs syndrome, muscle soreness, congestive heart failure, and recovery after coronary artery bypass surgery, there isn't enough reliable evidence in our data to rate whether it works or doesn't.

The evidence, ingredient by ingredient Ribose

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Ribose is generally well tolerated in the short term — up to about one month — but long-term safety hasn't been well studied. The most common side effects when taken by mouth are diarrhea, gastrointestinal discomfort, headache, low blood sugar (hypoglycemia), and nausea.

Some people have also reported a hyperanxious feeling, lightheadedness, increased appetite, and mild anxiety; lowering the dose resolved these symptoms in at least one study. There isn't enough safety information to recommend D-Ribose during pregnancy or while breastfeeding — talk with your doctor or pharmacist for personalized advice if you're pregnant, planning to become pregnant, or nursing.

Side effects, ingredient by ingredient Ribose

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Ribose.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take insulin or any antidiabetes drug (like metformin, glyburide, or sulfonylureas), check with your doctor or pharmacist before starting D-Ribose. Both carry a Moderate risk of increased low blood sugar, and you may need to monitor your blood glucose more closely or adjust your doses.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

D-Ribose may be worth considering if you're interested in its potential energy-support role, but the evidence for most claimed uses is either limited or not favorable. The main caution is low blood sugar, especially if you take insulin or antidiabetes medications.

Before you start, check your exact medications with your own doctor or pharmacist, and don't stop or adjust any blood sugar medication on your own.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about D-Ribose 700 mg, straight from the product label.

Brand Nova Nutritions
Barcode (UPC) 732363270331
Net contents 180 Veggie Capsule(s)
Market status On market
Date entered into DSLD Jun 24, 2020
DSLD ID 229299
Product type Fiber And Other Nutrients
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for D-Ribose 700 mg by Nova Nutritions, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Vegetarian Capsule(s)
Maximum serving Sizes:
6 Vegetarian Capsule(s)
Servings per container
90
UPC/BARCODE
732363270331
IngredientAmount% DV
Calories6 Calorie(s)--
Total Carbohydrates1.4 Gram(s)1%
Total Sugars1.4 Gram(s)--
D-Ribose, Powder1.4 Gram(s)--

Other ingredients: Cellulose, Silicon Dioxide, Microcrystalline Cellulose, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

D-ribose is a naturally occurring sugar used by every cell in the body. It's an essential compound in energy metabolism that serves as a building block for adenosine triphosphate (ATP)- the boy's basic energy source. D-ribose is also the backbone of genetic material, DNA and RNA. Studies have shown that ribose supplementation can enhance cardiac energy levels and support cardiovascular metabolism. Further studies suggest that ribose plays a role in supporting energy recovery after exercise. Exercise increases free radical production in muscle tissue. Ribose may strengthen and support the body's crucial antioxidant defenses.

Precautions

Caution: For adults only, if you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of the reach of children.

Do not use if safety seal is broken or missing.

Storage

Keep in cool, dry place.

FDA Disclaimer Statement

These statement have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Promotes energy production & healthy cardiovascular function

Free of: Artificial color, preservatives, sugar, starch, milk, corn, gluten, wheat, yeast, fish.

GMP Good Manufacturing Practice Product

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take two (2) to six (6) Vcaps daily, prior to exercise. Serious athletes may want to double the dosage during training.

Seals/Symbols

GMP Good Manufacturing Practice Product Made in USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

D-Ribose 700 mg by Nova Nutritions label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

D-Ribose 700 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in D-Ribose 700 mg by Nova Nutritions

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Vegetarian Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

D-Ribose, Powder

Interacts with
86 drugs
1.4 Gram(s) per serving

Ribose (D-ribose) is a simple sugar your body makes naturally and uses to build energy molecules like ATP. Some people take it for fatigue, fibromyalg...

D-Ribose, Powder monograph & interactions

Other (inactive) ingredients: Cellulose, Silicon Dioxide, Microcrystalline Cellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

D-Ribose 700 mg by Nova Nutritions Drug Interactions

Want to check YOUR meds against D-Ribose 700 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

D-Ribose, Powder 86

Individual Drug Interactions

The ingredients in D-Ribose 700 mg interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in D-Ribose 700 mg interact with drugs. Each result below shows which ingredient is responsible. D-Ribose, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in D-Ribose 700 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

D-Ribose, Powder2 drug types · 86 drugs

Antidiabetes Drugs

Theoretically, taking ribose in combination with antidiabetes drugs might increase the risk of hypoglycemia.
In clinical research, ribose decreases serum glucose levels in a dose-dependent manner.

Likelihood Probable Evidence B
Insulin

Theoretically, taking ribose with insulin could increase the hypoglycemic effect of insulin.
In clinical pharmacokinetic studies, oral administration of ribose modestly increased serum insulin levels.

Likelihood Possible Evidence B
D-Ribose, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for D-Ribose 700 mg, from the product label.

Nova Nutritions

See all Nova Nutritions products
Name
Nova Nutritions
City
Scotch Plains
State
New Jersey
ZipCode
07076
Web Address
www.novanutritions.com
Pharmacist Counseling Corner

D-Ribose 700 mg by Nova Nutritions: Common Questions

Does D-Ribose 700 mg by Nova Nutritions interact with any medications?
Yes. Based on its ingredients, D-Ribose 700 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
D-Ribose 700 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will D-Ribose give me more energy?
There isn't enough reliable evidence in our data to say whether D-Ribose boosts energy or endurance. For athletic performance specifically, the available evidence suggests it is possibly ineffective.
What are the main side effects I should watch for?
The most common side effects are diarrhea, gastrointestinal upset, headache, nausea, and low blood sugar. Some people report anxiety, lightheadedness, or increased appetite, though lowering the dose often helps. If you experience low blood sugar symptoms — shakiness, sweating, confusion — stop and contact your doctor.
Can I take D-Ribose while I'm pregnant or breastfeeding?
There isn't enough safety information to recommend D-Ribose in pregnancy or while breastfeeding. Talk with your doctor or pharmacist about whether it's right for you in these situations.
Can I take D-Ribose with my diabetes medication?
Possibly, but you need to check with your doctor first. Ribose can lower blood sugar on its own, so combined with antidiabetes drugs or insulin, you may be at higher risk for low blood sugar and might need dose adjustments or closer monitoring.
How long is it safe to use D-Ribose?
The evidence shows D-Ribose is generally well tolerated for up to about one month. Long-term safety hasn't been well studied, so talk with your pharmacist about how long you plan to use it.
What's in the capsule besides D-Ribose?
The capsule contains cellulose, silicon dioxide, microcrystalline cellulose, and magnesium stearate — standard inactive ingredients that help hold the supplement together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if D-Ribose 700 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

D-Ribose 700 mg label
Go deeper

The Full Monographs Behind D-Ribose 700 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Ribose

Interacts with 86 drugs

Ribose (D-ribose) is a simple sugar your body makes naturally and uses to build energy molecules like ATP. Some people take it for fatigue, fibromyalgia, exercise recovery, or heart conditio...

Read the full Ribose monograph →
Sources

Sources & How We Checked

D-Ribose 700 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ribose 8 references
  1. Segal S, Foley J. The metabolism of D-ribose in man. J Clin Invest 1958;37:719-35. PubMed
  2. Perlmutter NS, Wilson RA, Angello DA, et al. Ribose facilitates thallium-201 redistribution in patients with coronary artery disease. J Nucl Med 1991;32:193-200.
  3. Hegewald MG, Palac RT, Angello DA, et al. Ribose infusion accelerates thallium redistribution with early imaging compared with late 24-hour imaging without ribose. J Am Coll Cardiol 1991;18:1671-81. PubMed
  4. Pliml W, von Arnim T, Stalein A, et al. Effects of ribose on excercise-induced ischaemia in stable coronary artery disease. Lancet 1992;340:507-10.
  5. Burke ER. D-Ribose What You Need To Know. Garden City Park, NY: Avery Publishing Group 1999;1-43.
  6. Gross M, Reiter S, Zollner N. Metabolism of D-ribose administered continuously to healthy persons and to patients with myoadenylate deaminase deficiency. Klin Wochenschr 1989;67:1205-13. PubMed
  7. Teitelbaum JE, Johnson C, St Cyr J. The use of D-ribose in chronic fatigue syndrome and fibromyalgia: a pilot study. J Altern Complement Med 2006;12:857-62. PubMed
  8. Thompson J, Neutel J, Homer K, Tempero K, Shah A, Khankari R. Evaluation of D-ribose pharmacokinetics, dose proportionality, food effect, and pharmacodynamics after oral solution administration in healthy male and female subjects. J Clin Pharmacol 2014;54 PubMed

See these in context on the Ribose monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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