Major interaction on record — check this product against your medications before combining. Based on 2 of 5 ingredients. Check your meds →
Dietary supplement

Peak BCAA Watermelon Ingredients & Drug Interactions

by Inner Armour Sports Nutrition

Peak BCAA Watermelon label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Peak BCAA Watermelon against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Peak BCAA Watermelon is a dietary supplement by Inner Armour Sports Nutrition with 5 active ingredients. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 218 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Calcium, L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Peak BCAA Watermelon by Inner Armour Sports Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Peak BCAA Watermelon by Inner Armour Sports Nutrition — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Peak BCAA Watermelon by Inner Armour Sports Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • “BCAA Peak” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

Peak BCAA Watermelon contains 5 active ingredients: three branched-chain amino acids (L-leucine, L-isoleucine, and L-valine, collectively called BCAAs), plus L-glutamine and calcium. The product also includes inactive ingredients — citric acid, natural and artificial flavors, sucralose, and acesulfame potassium — that give it taste and texture but don't provide nutritional benefit.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle building and sports performance.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Postoperative recovery, Muscle recovery, Sports nutrition, Strength training.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for Postoperative recovery (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance.
  • Also on file: Calcium is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle damage.

The data we hold covers only L-glutamine from this product. Glutamine is rated Effective for sickle cell disease and Possibly Effective for HIV/AIDS-related wasting, postoperative recovery, and critical illness following trauma.

We have no effectiveness information on file for the three BCAAs (L-leucine, L-isoleucine, L-valine) or calcium's role when combined with them in this particular formulation.

The evidence, ingredient by ingredient Glutamine Calcium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-glutamine is generally well tolerated by healthy adults. Common side effects from oral glutamine are belching, bloating, constipation, diarrhea, flatulence, nausea, vomiting, headache, and stomach pain — especially at higher doses (10–30 grams daily).

Rare cases of dizziness and, in people with bipolar disorder, mania or hypomania have been reported. People with kidney or liver disease should use glutamine only under medical supervision.

Calcium is also well tolerated at recommended doses; the most common side effects are belching, constipation, diarrhea, flatulence, and stomach upset. Very high doses raise theoretical concerns about kidney stones and may be linked to cardiovascular or prostate health risks in some populations.

For L-glutamine in pregnancy and lactation, safety data are limited — talk with your doctor or pharmacist for personalized advice. Calcium is rated Likely Safe in pregnancy at recommended amounts, though one entry notes possibly unsafe; Likely Safe during breastfeeding at recommended amounts.

Side effects, ingredient by ingredient Glutamine Calcium

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Calcium, Glutamine.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: seizure medications; heart-rhythm medications; lithium.
  • For scale: 218 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Peak BCAA Watermelon, check with your own doctor or pharmacist if you take HIV integrase inhibitors (dolutegravir or elvitegravir), ceftriaxone antibiotics, the HIV drug raltegravir, levothyroxine (thyroid medication), sotalol, calcipotriene, diltiazem, or anticonvulsants — these all have documented interactions with ingredients in this product, ranging from Major to Moderate severity.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Peak BCAA Watermelon is a branched-chain amino acid supplement with added glutamine and calcium. If you take HIV medications, thyroid drugs, anticonvulsants, heart or blood pressure medications, or antibiotics — especially ceftriaxone — you'll need to check with your doctor or pharmacist before starting this product, because calcium and glutamine have documented interactions with these drug types.

Otherwise, it's generally well tolerated, though digestive side effects are common at higher doses.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Peak BCAA Watermelon, straight from the product label.

Brand Inner Armour Sports Nutrition
Barcode (UPC) 183859201856
Net contents 354 Gram(s); 12.5 oz.
Market status On market
Date entered into DSLD Feb 23, 2016
DSLD ID 54077
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Peak BCAA Watermelon by Inner Armour Sports Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
11.8 Gram(s)
Maximum serving Sizes:
11.8 Gram(s)
Servings per container
15
UPC/BARCODE
183859201856
IngredientAmount% DV
L-Glutamine5 Gram(s), 2.5 Gram(s)--
L-Leucine12.4 Gram(s), 6.2 Gram(s)--
L-Isoleucine1000 mg, 500 mg--
L-Valine1000 mg, 500 mg--
Calcium72 mg, 36 mg7%, 4%
BCAA Peak0 NP, 0 NP--

Other ingredients: Citric Acid, Natural & Artificial flavors, Sucralose, Acesulfame Potassium

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

{Chart} {Red}Leucine 12:1:1 The Most Poweful Muscle Building BCAA Ratio in The World. 6.2 g of Leucine: The clinically studied dose in every scoop! {Grey} isoleucine {White} Valine The 3 BCAAs (Branched-Chain Amino Acids) {Red} LEUCINE The Muscle Building Phenom Leucine is by far the most powerful of the 3 BCAAs as it cannot convert to energy. This muscle building superstar is strictly ketogenic, so it is used to trigger muscle protein synthesis (growth).* {Grey} ISOLEUCINE Essential Amino Acid Isoleucine while essential, is both glucogenic and ketogenic, and can be converted to glucose for energy during your workout.* {White} VALINE Essential Amino Acid Valine while essential, is strictly glucogenic and can also be converted to glucose for energy during your workout.* GLUTAMINE Clinical Dose 2.5g to 5g Glutamine makes up approximately 60% of muscle tissue. It has been shown to act as a powerful muscle cell volumizer, stimulate protein synthesis and decrease muscle protein loss.*

***Informed-Choice is a quality assurance program for sports nutrition products. The program certifies that all nutritional supplements that bear the Informed-Choice logo have been tested for banned substances by the world class sports anti-doping lab, LGC.

New Instantized Formula 30 servings

BANNED SUBSTANCE FREE

Leucine Loaded 12:1:1

Naturally & Artificially Flavored

Manufactured in a GMP certified facility.

12:1:1 Ratio Leucine Loaded

General

IA BLK BCAA PL 30 2/15 MJ V2.7

Formula

6.2 G Leucine 2.5 G Glutamine

Formulation

No fillers No dyes Gluten free

Seals/Symbols

INFORMED-CHOICE .ORG Trusted by sport

FDA Statement of Identity

Dietary Supplement

Precautions

Allergen Information: Produced in a facility that also processes milk, tree nuts, peanuts, eggs, soy, shellfish, fish, and wheat.

Do not purchase if seal is broken.

Keep out of reach of children.

Consult your healthcare professional prior to use if you have or suspect a medical condition, are taking prescription drugs, or are pregnant, or lactating.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, mix 1 scoop with 16 oz of water and consume before, during and/or after training. BCAA Peak is best taken in one of two ways: 1. As a pre/intra workout drink mix. 2. Immediately after exercise and before your post workout shake (Nitro-Peak or Mass-Peak). Additional servings may be used to meet your daily amino acid requirements.

Storage

Protect from heat, light and moisture.

Store at 15-30(0)C (59-86(0)F).

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Peak BCAA Watermelon by Inner Armour Sports Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Peak BCAA Watermelon label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Peak BCAA Watermelon by Inner Armour Sports Nutrition

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size11.8 Gram(s) Dosage formPowder Servings per container15 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Glutamine

Interacts with
50 drugs
5 Gram(s) per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions

Calcium

Interacts with
168 drugs
72 mg per serving Form: Calcium Silicate

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet f...

Calcium monograph & interactions

BCAA Peak

0 NP per serving
  • › L-Leucine
  • › L-Isoleucine
  • › L-Valine

Other (inactive) ingredients: Citric Acid, Natural & Artificial flavors, Sucralose, Acesulfame Potassium. These complete the product’s ingredient list but are not active constituents.

Interaction report

Peak BCAA Watermelon by Inner Armour Sports Nutrition Drug Interactions

Want to check YOUR meds against Peak BCAA Watermelon?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
218Drugs
7 Major 193 Moderate 18 Minor

Ingredients driving the most interactions

Calcium 168
L-Glutamine 50

Individual Drug Interactions

The ingredients in Peak BCAA Watermelon interact with 218 drugs. Click any drug to see the details.

2 of the 5 ingredients in Peak BCAA Watermelon interact with drugs. Each result below shows which ingredient is responsible. Calcium L-Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in Peak BCAA Watermelon with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Calcium18 drug types · 168 drugs

Ceftriaxone (Rocephin)

Co-administration of intravenous calcium and ceftriaxone can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys.
Avoid administering intravenous calcium in any form, such as parenteral nutrition or Lactated Ringers, within 48 hours of intravenous ceftriaxone. Case reports in neonates show that administering intravenous ceftriaxone and calcium can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys. In several cases, neonates have died as a result of this interaction. So far there are no reports in adults; however, there is still concern that this interaction might occur in adults.

Likelihood Probable Evidence D
Dolutegravir (Tivicay)

Calcium seems to reduce levels of dolutegravir.
Advise patients to take dolutegravir either 2 hours before or 6 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium carbonate 1200 mg concomitantly with dolutegravir 50 mg reduces plasma levels of dolutegravir by almost 40%. Calcium appears to decrease levels of dolutegravir through chelation.

Likelihood Probable Evidence B
Elvitegravir (Vitekta)

Calcium seems to reduce levels of elvitegravir.
Advise patients to take elvitegravir either 2 hours before or 2 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium along with elvitegravir can reduce blood levels of elvitegravir through chelation.

Likelihood Probable Evidence B
Aluminum

Calcium citrate might increase aluminum absorption and toxicity. Other types of calcium do not increase aluminum absorption.
Calcium citrate can increase the absorption of aluminum when taken with aluminum hydroxide. The increase in aluminum levels may become toxic, particularly in individuals with kidney disease. However, the effect of calcium citrate on aluminum absorption is due to the citrate anion rather than calcium cation. Calcium acetate does not appear to increase aluminum absorption.

Likelihood Possible Evidence B
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Calcium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide and calcium can be taken together if taken with food. However, if taken on an empty stomach, bictegravir/emtricitabine/tenofovir alafenamide should not be taken with, or 2 hours after, calcium containing products.

Likelihood Probable Evidence D
Bisphosphonates

Calcium reduces the absorption of bisphosphonates.
Advise patients to take bisphosphonates at least 30 minutes before calcium, but preferably at a different time of day. Calcium supplements decrease absorption of bisphosphonates.

Likelihood Probable Evidence C
Calcipotriene (Dovonex)

Taking calcipotriene with calcium might increase the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with calcium supplements might increase the risk of hypercalcemia.

Likelihood Possible Evidence B
Digoxin (Lanoxin)

Using intravenous calcium with digoxin might increase the risk of fatal cardiac arrhythmias.
Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. However, one retrospective analysis of clinical data suggests that intravenous calcium does not increase the risk of dysrhythmias or mortality in patients receiving digoxin.

Likelihood Possible Evidence B
Diltiazem (Cardizem, Others)

Theoretically, calcium may reduce the therapeutic effects of diltiazem.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, calcium might increase this risk of hypercalcemia and reduce the effectiveness of diltiazem.

Likelihood Probable Evidence D
Levothyroxine (Synthroid, Others)

Calcium seems to reduce the absorption and effectiveness of levothyroxine.
Advise patients to take levothyroxine and calcium supplements at least 4 hours apart. Calcium reduces levothyroxine absorption, probably by forming insoluble complexes. Calcium carbonate supplements reduce effectiveness of levothyroxine in patients with hypothyroidism.

Likelihood Probable Evidence B
Lithium

Theoretically, concomitant use of calcium and lithium may increase this risk of hypercalcemia.
Clinical research suggests that long-term use of lithium may cause hypercalcemia in 10% to 60% of patients. Theoretically, concomitant use of lithium and calcium supplements may further increase this risk.

Likelihood Possible Evidence B
Quinolone Antibiotics

Calcium seems to reduce the absorption of quinolone antibiotics.
Advise patients to take oral quinolones at least 2 hours before or 4-6 hours after calcium supplements or calcium-fortified foods. Taking calcium at the same time as oral quinolones can reduce quinolone absorption. Calcium binds to quinolones in the gut.

Likelihood Probable Evidence B
Raltegravir (Isentress)

Calcium may reduce levels of raltegravir.
Pharmacokinetic research shows that taking a single dose of calcium carbonate 3000 mg along with raltegravir 400 mg twice daily modestly decreases the mean area under the curve of raltegravir, but the decrease does not necessitate a dose adjustment of raltegravir. However, a case of elevated HIV-1 RNA levels and documented resistance to raltegravir has been reported for a patient taking calcium carbonate 1 gram three times daily plus vitamin D3 (cholecalciferol) 400 IU three times daily in combination with raltegravir 400 mg twice daily for 11 months. It is thought that calcium reduced raltegravir levels by chelation, leading to treatment failure.

Likelihood Possible Evidence B
Sotalol (Betapace)

Calcium seems to reduce the absorption of sotalol.
Advise patients to separate doses by at least 2 hours before or 4-6 hours after calcium. Calcium appears to reduce the absorption of sotalol, probably by forming insoluble complexes.

Likelihood Possible Evidence B
Tetracycline Antibiotics

Calcium seems to reduce the absorption of tetracycline antibiotics.
Advise patients to take oral tetracyclines at least 2 hours before, or 4-6 hours after calcium supplements. Taking calcium at the same time as oral tetracyclines can reduce tetracycline absorption. Calcium binds to tetracyclines in the gut.

Likelihood Probable Evidence C
Thiazide Diuretics

Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Thiazides reduce calcium excretion by the kidneys. Using thiazides along with moderately large amounts of calcium carbonate increases the risk of milk-alkali syndrome (hypercalcemia, metabolic alkalosis, renal failure). Patients may need to have their serum calcium levels and/or parathyroid function monitored regularly.

Likelihood Probable Evidence C
Verapamil (Calan, Others)

Theoretically, calcium may reduce the therapeutic effects of verapamil.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, use of calcium supplements may increase this risk of hypercalcemia and reduce the effectiveness of verapamil.

Likelihood Probable Evidence D
Calcium Channel Blockers

Intravenous calcium may decrease the effects of calcium channel blockers; oral calcium is unlikely to have this effect.
Intravenous calcium is used to decrease the effects of calcium channel blockers in the management of overdose. Intravenous calcium gluconate has been used before intravenous verapamil (Isoptin) to prevent or reduce the hypotensive effects without affecting the antiarrhythmic effects. But there is no evidence that dietary or supplemental calcium when taken orally interacts with calcium channel blockers.

Likelihood Unlikely Evidence D
Calcium full monograph & interactions

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Peak BCAA Watermelon, from the product label.

Inner Armour Sports Nutrition

See all Inner Armour Sports Nutrition products
Web Address
www.innerarmour.com
Pharmacist Counseling Corner

Peak BCAA Watermelon by Inner Armour Sports Nutrition: Common Questions

Does Peak BCAA Watermelon by Inner Armour Sports Nutrition interact with any medications?
Yes. Based on its ingredients, Peak BCAA Watermelon has a known interaction with 218 medications, including 7 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Peak BCAA Watermelon contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this product affect my levothyroxine (Synthroid)?
Yes — calcium in this product can reduce how much levothyroxine your body absorbs and make it less effective. To avoid this, take your levothyroxine and this supplement at least 4 hours apart. Check with your pharmacist about the best timing for your routine.
What are the most common side effects of taking this product?
Belching, bloating, constipation, diarrhea, flatulence, nausea, vomiting, and stomach pain are the side effects most often reported, especially when taking higher doses. These generally settle with lower amounts or if you take it with food.
Is L-glutamine safe to take while I'm pregnant?
Safety data for supplemental L-glutamine in pregnancy are limited. There isn't enough information to say whether it's safe or not. Talk with your doctor or pharmacist to decide what's right for your situation.
Can I take this if I have kidney disease?
People with kidney or liver disease should only use L-glutamine under medical supervision. Check with your doctor or pharmacist before starting this product.
Is this safe to use while breastfeeding?
L-glutamine: safety data during breastfeeding are limited, so talk with a clinician before use. Calcium: it's generally considered safe at recommended amounts during breastfeeding. Overall, check with your doctor or pharmacist before starting.
Will this interfere with my HIV medications?
Possibly, depending on which HIV drug you take. Calcium in this product can significantly lower blood levels of dolutegravir, elvitegravir, and raltegravir. If you take any HIV integrase inhibitor, talk with your pharmacist about timing — you may need to separate doses by several hours.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Peak BCAA Watermelon label
Go deeper

The Full Monographs Behind Peak BCAA Watermelon’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph → Herb & supplement monograph

Calcium

Interacts with 168 drugs

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet falls short. Most people do best getting...

Read the full Calcium monograph →
Sources

Sources & How We Checked

Peak BCAA Watermelon's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 73 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Calcium 62 references
  1. Shils M, Olson A, Shike M. Modern Nutrition in Health and Disease. 8th ed. Philadelphia, PA: Lea and Febiger, 1994.
  2. Hernandez-Avila M, Gonzalez-Cossio T, Hernandez-Avila JE, et al. Dietary calcium supplements to lower blood lead levels in lactating women: a randomized placebo-controlled trial. Epidemiology 2003;14:206-12.. PubMed
  3. Thys-Jacobs S, Ceccarelli S, Bierman A, et al. Calcium supplementation in premenstrual syndrome: a randomized crossover trial. J Gen Intern Med 1989;4:183-9. PubMed
  4. Maton PN, Burton ME. Antacids revisited: a review of their clinical pharmacology and recommended therapeutic use. Drugs 1999;57:855-70.
  5. Clemens JD, Feinstein AR. Calcium carbonate and constipation: a historical review of medical mythopoeia. Gastroenterology 1977;72:957-61. DOI
  6. Saunders D, Sillery J, Chapman R. Effect of calcium carbonate and aluminum hydroxide on human intestinal function. Dig Dis Sci 1988;33:409-13. PubMed
  7. Friedman PA, Bushinsky DA. Diuretic effects on calcium metabolism. Semin Nephrol 1999;19:551-6.
  8. Koo WK, Walters JC, Esterlitz J, et al. Maternal calcium supplementation and fetal bone mineralization. Obstet Gynecol 1999;94:577-82. DOI
  9. Raman L, Rajalakshmi K, Krishnamachari KAVR, et al. Effect of calcium supplementation to undernourished mothers during pregnancy on the bone density of the neonates. Am J Clin Nutr 1978; 31:466-9. DOI
  10. Murry JJ, Healy MD. Drug-mineral interactions: a new responsibility for the hospital dietician. J Am Diet Assoc 1991;91:66-73.
  11. Chan JM, Giovannucci E, Andersson SO, et al. Dairy products, calcium, phosphorous, vitamin D, and risk of prostate cancer. Cancer Causes Control 1998;9:559-66.
  12. Butner LE, Fulco PP, Feldman G, et al. Calcium carbonate-induced hypothyroidism. Ann Intern Med 2000:132:595. PubMed
  13. Schneyer CR. Calcium carbonate and reduction of levothyroxine efficacy. JAMA 1998;279:750. PubMed
  14. Moser LR, Smythe MA, Tisdale JE. The use of calcium salts in the prevention and management of verapamil-induced hypotension. Ann Pharmacother 2000;34:622-9. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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