Major interaction on record — check this product against your medications before combining. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Performax Forte Ingredients & Drug Interactions

by Aloha Medicinals

Performax Forte label
See full label image
Other (e.g. Tea Bag) Category: Botanical With Nutrients
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Performax Forte against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Performax Forte is a dietary supplement by Aloha Medicinals with 4 active ingredients. Its ingredients are commonly taken for fatigue and low energy, stress and coping (adaptogen), mental performance and focus.Based on those ingredients, 1,443 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Rhodiola rosea Extract, Magnesium Lysyl Glycinate Chelate, Chromium Nicotinate Glycinate Chelate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Performax Forte by Aloha Medicinals

Ask about any prescription or over-the-counter medication and we check it for interactions with Performax Forte by Aloha Medicinals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Performax Forte by Aloha Medicinals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 6 active ingredients.
  • “Proprietary Formula” is a proprietary blend — the label gives one combined amount (750 mg) without saying how much of each component you get.
  • “Full Spectrum MycoProducts” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

Performax Forte contains 6 active ingredients. Rhodiola rosea extract is an adaptogen traditionally used for stress and energy support.

Magnesium (as magnesium lysyl glycinate chelate) is an essential mineral supporting muscle and nerve function. The product includes three cordyceps species — Cordyceps sinensis alohaensis Hybrid, Cordyceps sinensis, and Cordyceps militaris — which are fungi traditionally valued in some practices for stamina and endurance.

Chromium nicotinate glycinate chelate is a trace mineral involved in glucose regulation. Two proprietary blends — "Proprietary Formula" and "Full Spectrum MycoProducts" — contain undisclosed component ingredients listed individually elsewhere.

The product also contains inactive ingredients including cellulose, tapioca maltodextrin, carnauba wax, tapioca syrup, nu-flow, and white milo.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: energy, stamina, strength and athletic performance.
  • We looked for evidence on: Athletic performance, Chronic fatigue syndrome (CFS), Fatigue, Exercise-induced muscle soreness, endurance, physical stamina — and 1 related terms.
  • The closest evidence on file: Cordyceps is rated "Possibly Ineffective" for Athletic performance (Natural Medicines).
  • Also on file: Magnesium is rated "Possibly Ineffective" for Athletic performance.
  • Also on file: Cordyceps is rated "Insufficient Reliable Evidence To Rate" for Fatigue.

The evidence for Performax Forte's ingredients is mixed. Magnesium shows effective evidence for constipation, indigestion (dyspepsia), and magnesium deficiency.

Chromium is likely effective for chromium deficiency and possibly effective for type 2 diabetes support. Rhodiola and the cordyceps species, however, show insufficient evidence for most of their traditional uses — these include athletic performance, sexual dysfunction, and various respiratory or heart conditions.

Cordyceps research specifically suggests it may be ineffective for athletic performance. The data we hold does not establish reliable effectiveness for most of the product's marketed purposes.

The evidence, ingredient by ingredient Rhodiola Magnesium Chromium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Rhodiola is generally well tolerated for short-term use, though long-term safety hasn't been well studied. Common side effects include dizziness and increased or decreased saliva production.

Magnesium is generally safe at recommended amounts and is typically well tolerated orally, though it can cause diarrhea, nausea, vomiting, or gastrointestinal irritation in some people. Cordyceps is generally well tolerated for up to one year, with uncommon side effects including abdominal discomfort, diarrhea, constipation, and dry mouth; these often improve when taken after eating.

One rare case of liver inflammation (hepatitis) has been reported, though it's unclear if cordyceps or a contaminant was responsible. Chromium is generally well tolerated at typical supplement doses but can cause gastrointestinal irritation, headaches, insomnia, and mood changes.

Regarding pregnancy and breastfeeding: rhodiola and cordyceps lack sufficient safety data and should be avoided during pregnancy and breastfeeding. Magnesium is needed during pregnancy but should be used only under a doctor's guidance; normal dietary amounts are appropriate while breastfeeding.

Chromium from a balanced diet or prenatal vitamin is generally acceptable in pregnancy, but extra supplements should be avoided unless a doctor recommends it; higher supplement doses lack sufficient safety data while breastfeeding.

Side effects, ingredient by ingredient Rhodiola Magnesium Chromium

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Cordyceps, Rhodiola, Chromium, Magnesium.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; heart-rhythm medications; Parkinson's medications.
  • For scale: 1,444 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Performax Forte, double-check with your doctor or pharmacist if you take: Parkinson's medication (levodopa/carbidopa) — magnesium can significantly reduce its effectiveness. Blood pressure medications (especially calcium channel blockers like nifedipine or amlodipine, or other antihypertensives) — may cause dangerously low blood pressure.

Blood thinners or antiplatelet drugs (such as warfarin, apixaban, or aspirin used for clotting prevention) — cordyceps may theoretically increase bleeding risk. Immune-suppressing medications — cordyceps and rhodiola may interfere with effectiveness.

Diabetes or insulin medications — both chromium and rhodiola may increase the risk of low blood sugar. Thyroid medication (levothyroxine/Synthroid) — chromium can reduce absorption.

Muscle relaxants, quinolone antibiotics, bone medications (bisphosphonates), or sulfonylurea diabetes drugs — magnesium interactions documented.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with graded evidence leaning against its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Performax Forte contains active ingredients with limited effectiveness evidence for most marketed uses and carries documented interactions with common medications, including a Major interaction with Parkinson's medication. This product is not appropriate for anyone taking levodopa/carbidopa or blood thinners without cleared consultation with their doctor or pharmacist.

If you take any prescription medication, thyroid medication, diabetes medication, or muscle relaxants, talk through this product with your own healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Performax Forte, straight from the product label.

Brand Aloha Medicinals
Barcode (UPC) 835186006061
Net contents 90 Caplet(s)
Market status On market
Date entered into DSLD Jan 24, 2024
DSLD ID 304757
Product type Botanical With Nutrients
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Performax Forte by Aloha Medicinals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Caplet(s)
Maximum serving Sizes:
3 Caplet(s)
Servings per container
90
UPC/BARCODE
835186006061
IngredientAmount% DV
Rhodiola rosea Extract0 NP--
Proprietary Formula750 mg--
Magnesium Lysyl Glycinate Chelate0 NP--
Full Spectrum MycoProducts0 NP--
Cordyceps sinensis alohaensis Hybrid0 NP--
Cordyceps sinensis0 NP--
Cordyceps militaris0 NP--
Chromium Nicotinate Glycinate Chelate0 NP--

Other ingredients: Nu-Flow, Carnauba Wax, Tapioca Maltodextrin, Tapioca Syrup, Cellulose, White Milo

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Do not use if tamper evident seal is broken

When pregnant or nursing, consult a health care professional before use.

General Statements

Questions or comments? Toll-free 1-877-835-6091

New!

750 mg each

Suggested/Recommended/Usage/Directions

Suggested use: 1-3 caplets per day with meals.

Formula

Performax Forte is a combination of cordyceps strains, performance enhancing minerals, and oxygenating rhodiola specifically formulated to provide optimum health, endurance and maximum performance for today's active lifestyle.

Formulation

Ultimate sports nutrition Supports energy, stamina, strength All natural

Seals/Symbols

Made in USA

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Performax Forte by Aloha Medicinals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Performax Forte label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Performax Forte by Aloha Medicinals

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Caplet(s) Dosage formOther (e.g. Tea Bag) Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Formula

750 mg per serving

Other (inactive) ingredients: Nu-Flow, Carnauba Wax, Tapioca Maltodextrin, Tapioca Syrup, Cellulose, White Milo. These complete the product’s ingredient list but are not active constituents.

Interaction report

Performax Forte by Aloha Medicinals Drug Interactions

Want to check YOUR meds against Performax Forte?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,443Drugs
6 Major 818 Moderate 619 Minor

Ingredients driving the most interactions

Rhodiola rosea Extract 1,271
Magnesium Lysyl Glycinate Chelate 295
Chromium Nicotinate Glycinate Chelate 178

Individual Drug Interactions

The ingredients in Performax Forte interact with 1,443 drugs. Click any drug to see the details.

3 of the 4 ingredients in Performax Forte interact with drugs. Each result below shows which ingredient is responsible. Rhodiola rosea Extract Magnesium Lysyl Glycinate Chelate Chromium Nicotinate Glycinate Chelate

Each ingredient & the kinds of drugs it affects

For each ingredient in Performax Forte with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Rhodiola rosea Extract10 drug types · 1,271 drugs

Antidiabetes Drugs

Theoretically, taking rhodiola with antidiabetes drugs might increase the risk of hypoglycemia.
In vitro and animal research shows that rhodiola extract can decrease blood glucose due to alpha-glucosidase activity.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, taking rhodiola with antihypertensive drugs might increase the risk of hypotension.
In vitro and animal research shows that rhodiola extract inhibits angiotensin-converting enzyme (ACE) and might lower blood pressure.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, rhodiola might increase levels of drugs metabolized by CYP2C9.
In vitro research shows that rhodiola inhibits CYP2C9. This effect is highly variable and appears to be dependent on the rhodiola product studied. Also, a clinical study in healthy young males found that taking rhodiola extract 290 mg daily for 14 days reduces the metabolism of losartan, a CYP2C9 substrate, by 21% after 4 hours.

Likelihood Possible Evidence B
Immunosuppressants

Theoretically, rhodiola use might interfere with immunosuppressive therapy.
In vitro and animal research show that rhodiola has immunostimulatory effects.

Likelihood Possible Evidence D
Losartan (Cozaar)

Rhodiola might increase the levels and adverse effects of losartan.
A clinical study in healthy young males found that taking rhodiola extract 290 mg daily for 14 days reduces the metabolism of losartan, a CYP2C9 substrate, by 21% after 4 hours.

Likelihood Probable Evidence B
P-Glycoprotein Substrates

Theoretically, rhodiola might increase levels of P-glycoprotein substrates.
In vitro research shows that rhodiola inhibits P-glycoprotein. Theoretically, using rhodiola with P-glycoprotein substrates might increase drug levels and potentially increase the risk of adverse effects.

Likelihood Possible Evidence D
Antidepressant Drugs

Theoretically, rhodiola might increase the risk of adverse effects when taken with antidepressants.
A review of adverse event reports in Poland identified cases of tachyarrhythmias, myalgia, arthralgia, gum pain, restless leg syndrome, swallowing disorders, and changes in consciousness when rhodiola was taken in combination with paroxetine, escitalopram, fluoxetine, sertraline, trazodone, and/or duloxetine.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, rhodiola might increase the risk of adverse effects when taken with CNS depressants.
A review of adverse event reports in Poland identified cases of excessive sedation, myoclonus, hypotension, and hallucinations when rhodiola was taken with haloperidol, diazepam, or alprazolam.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, rhodiola might increase levels of drugs metabolized by CYP1A2.
In vitro research shows that rhodiola inhibits CYP1A2. This effect is highly variable and appears to be dependent on the rhodiola product studied. However, a clinical study in healthy young males found that taking rhodiola extract 290 mg daily for 14 days does not inhibit the metabolism of caffeine, a CYP1A2 substrate.

Likelihood Possible Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, rhodiola might increase levels of drugs metabolized by CYP3A4.
In vitro research shows that rhodiola inhibits CYP3A4. This effect is highly variable and appears to be dependent on the rhodiola product studied. However, a clinical study in healthy young males found that taking rhodiola extract 290 mg daily for 14 days does not inhibit the metabolism of midazolam, a CYP3A4 substrate.

Likelihood Possible Evidence B
Rhodiola rosea Extract full monograph & interactions

Magnesium Lysyl Glycinate Chelate15 drug types · 295 drugs

Levodopa/Carbidopa (Sinemet)

Magnesium can reduce the bioavailability of levodopa/carbidopa.
Clinical research in healthy volunteers shows that taking magnesium oxide 1000 mg with levodopa 100 mg/carbidopa 10 mg reduces the area under the curve (AUC) of levodopa by 35% and of carbidopa by 81%. In vitro and animal research shows that magnesium produces an alkaline environment in the digestive tract, which might lead to degradation and reduced bioavailability of levodopa/carbidopa.

Likelihood Probable Evidence B
Aminoglycoside Antibiotics

Concomitant use of aminoglycoside antibiotics and magnesium can increase the risk for neuromuscular weakness.
Both aminoglycosides and magnesium reduce presynaptic acetylcholine release, which can lead to neuromuscular blockade and possible paralysis. This is most likely to occur with high doses of magnesium given intravenously.

Likelihood Possible Evidence D
Antacids

Use of acid reducers may reduce the laxative effect of magnesium oxide.
A retrospective analysis shows that, in the presence of H2 receptor antagonists (H2RAs) or proton pump inhibitors (PPIs), a higher dose of magnesium oxide is needed for a laxative effect. This may also occur with antacids. Under acidic conditions, magnesium oxide is converted to magnesium chloride and then to magnesium bicarbonate, which has an osmotic laxative effect. By reducing acidity, antacids may reduce the conversion of magnesium oxide to the active bicarbonate salt.

Likelihood Possible Evidence D
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Magnesium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide should be taken at least 2 hours before or 6 hours after magnesium containing products.

Likelihood Probable Evidence D
Bisphosphonates

Magnesium can decrease absorption of bisphosphonates.
Cations, including magnesium, can decrease bisphosphonate absorption. Advise patients to separate doses of magnesium and these drugs by at least 2 hours.

Likelihood Probable Evidence B
Calcium Channel Blockers

Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Magnesium inhibits calcium entry into smooth muscle cells and may therefore have additive effects with calcium channel blockers. Severe hypotension and neuromuscular blockades may occur when nifedipine is used with intravenous magnesium, although some contradictory evidence suggests that concurrent use of magnesium with nifedipine does not increase the risk of neuromuscular weakness. High doses of magnesium could theoretically have additive effects with other calcium channel blockers.

Likelihood Possible Evidence D
Digoxin

Magnesium salts may reduce absorption of digoxin.
Clinical evidence suggests that treatment with oral magnesium hydroxide or magnesium trisilicate reduces absorption of digoxin from the intestines. This may reduce the blood levels of digoxin and decrease its therapeutic effects.

Likelihood Possible Evidence B
Potassium-Sparing Diuretics

Potassium-sparing diuretics decrease excretion of magnesium, possibly increasing magnesium levels.
Potassium-sparing diuretics also have magnesium-sparing properties, which can counteract the magnesium losses associated with loop and thiazide diuretics. Theoretically, increased magnesium levels could result from concomitant use of potassium-sparing diuretics and magnesium supplements.

Likelihood Probable Evidence D
Quinolone Antibiotics

Magnesium decreases absorption of quinolones.
Magnesium can form insoluble complexes with quinolones and decrease their absorption. Advise patients to take these drugs at least 2 hours before, or 4 to 6 hours after, magnesium supplements.

Likelihood Probable Evidence D
Skeletal Muscle Relaxants

Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect.
Parenteral magnesium shortens the time to onset of skeletal muscle relaxants by about 1 minute and prolongs the duration of action by about 2 minutes. Magnesium potentiates the effects of skeletal muscle relaxants by decreasing calcium-mediated release of acetylcholine from presynaptic nerve terminals, reducing postsynaptic sensitivity to acetylcholine, and having a direct effect on the membrane potential of myocytes. Magnesium also has vasodilatory actions and increases cardiac output, allowing a greater amount of muscle relaxant to reach the motor end plate. A clinical study found that low-dose rocuronium (0.45 mg/kg), when given after administration of magnesium 30 mg/kg over 10 minutes, has an accelerated onset of effect, which matches the onset of effect seen with a full-dose rocuronium regimen (0.6 mg/kg). In another clinical study, onset times for rocuronium doses of 0.3, 0.6, and 1.2 mg/kg were 86, 76, and 50 seconds, respectively, when given alone, but were reduced to 66, 44, and 38 seconds, respectively, when the doses were given after a 15-minute infusion of magnesium sulfate 60 mg/kg. Giving intraoperative intravenous magnesium sulfate, 50 mg/kg loading dose followed by 15 mg/kg/hour, reduces the onset time of rocuronium, enhances its clinical effects, reduces the dose of intraoperative opiates, and prolongs the spontaneous recovery time. It does not affect the activity of subsequently administered neostigmine.

Likelihood Probable Evidence A
Sulfonylureas

Magnesium increases the systemic absorption of sulfonylureas, increasing their effects and side effects.
Clinical research shows that administration of magnesium hydroxide with glyburide increases glyburide absorption, increases maximal insulin response by 35-fold, and increases the risk of hypoglycemia, when compared with glyburide alone. A similar interaction occurs between magnesium hydroxide and glipizide. The mechanism of this effect appears to be related to the elevation of gastrointestinal pH by magnesium-based antacids, increasing solubility and enhancing absorption of sulfonylureas.

Likelihood Probable Evidence B
Tetracycline Antibiotics

Magnesium decreases absorption of tetracyclines.
Magnesium can form insoluble complexes with tetracyclines in the gut and decrease their absorption and antibacterial activity. Advise patients to take these drugs 1 hour before or 2 hours after magnesium supplements.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, magnesium may have antiplatelet effects, but the evidence is conflicting.
In vitro evidence shows that magnesium sulfate inhibits platelet aggregation, even at low concentrations. Some preliminary clinical evidence shows that infusion of magnesium sulfate increases bleeding time by 48% and reduces platelet activity. However, other clinical research shows that magnesium does not affect platelet aggregation, although inhibition of platelet-dependent thrombosis can occur.

Likelihood Unlikely Evidence B
Gabapentin (Neurontin)

Gabapentin absorption can be decreased by magnesium.
Clinical research shows that giving magnesium oxide orally along with gabapentin decreases the maximum plasma concentration of gabapentin by 33%, time to maximum concentration by 36%, and area under the curve by 43%. Advise patients to take gabapentin at least 2 hours before, or 4 to 6 hours after, magnesium supplements.

Likelihood Unlikely Evidence B
Sevelamer (Renagel, Renvela)

Sevelamer may increase serum magnesium levels.
In patients on hemodialysis, sevelamer use was associated with a 0.28 mg/dL increase in serum magnesium. The mechanism of this interaction remains unclear.

Likelihood Possible Evidence B
Magnesium Lysyl Glycinate Chelate full monograph & interactions

Chromium Nicotinate Glycinate Chelate5 drug types · 178 drugs

Antidiabetes Drugs

Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Some research shows that taking chromium might lower blood glucose levels, especially in patients with poorly controlled type 2 diabetes.

Likelihood Possible Evidence A
Insulin

Theoretically, concomitant use of chromium and insulin might increase the risk of hypoglycemia.
In clinical research, chromium has been shown to increase insulin sensitivity,

Likelihood Possible Evidence B
Levothyroxine (Synthroid, Others)

Chromium might bind levothyroxine in the intestinal tract and decrease levothyroxine absorption.
Clinical research in healthy volunteers shows that taking chromium picolinate 1000 mcg with levothyroxine 1 mg decreases serum levels of levothyroxine by 17% when compared to taking levothyroxine alone. Advise patients to take levothyroxine at least 30 minutes before or 3-4 hours after taking chromium.

Likelihood Probable Evidence B
Aspirin

Theoretically, aspirin might increase chromium absorption.
Animal research suggests that aspirin may increase chromium absorption and chromium levels in the blood.

Likelihood Possible Evidence D
Nonsteroidal Anti-Inflammatory Drugs (Nsaids)

NSAIDs might increase chromium levels in the body.
Drugs that are prostaglandin inhibitors, such as NSAIDs, seem to increase chromium absorption and retention.

Likelihood Possible Evidence D
Chromium Nicotinate Glycinate Chelate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Performax Forte, from the product label.

Aloha Medicinals

See all Aloha Medicinals products
Name
Aloha Medicinals
Street Address
2300 Arrowhead Dr
City
Carson City
State
NV
ZipCode
89706
Phone Number
877-835-6091
Web Address
www.alohamedicinals.com
Pharmacist Counseling Corner

Performax Forte by Aloha Medicinals: Common Questions

Does Performax Forte by Aloha Medicinals interact with any medications?
Yes. Based on its ingredients, Performax Forte has a known interaction with 1,443 medications, including 6 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Performax Forte contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Performax Forte if I'm pregnant or breastfeeding?
No for rhodiola and cordyceps — there isn't enough safety data, and the product facts advise against using them during pregnancy or while breastfeeding. Magnesium is needed in pregnancy but only under your doctor's guidance; normal dietary amounts are fine while breastfeeding. Chromium from diet or prenatal vitamins is generally acceptable in pregnancy, but extra supplement doses should be avoided unless your doctor recommends it. Talk to your doctor or pharmacist before taking this product.
What are the most common side effects?
Rhodiola may cause dizziness and increased or decreased saliva production. Magnesium commonly causes diarrhea, nausea, or vomiting. Cordyceps may cause constipation, diarrhea, or abdominal discomfort (often improved by taking it after eating). Chromium can cause gastrointestinal irritation, headaches, or mood changes.
Does this product really improve athletic performance?
The evidence doesn't support it. Rhodiola shows insufficient evidence for athletic performance, and cordyceps actually shows possibly ineffective evidence for athletic performance in the data we hold.
What is magnesium lysyl glycinate chelate?
It's a form of magnesium — an essential mineral — bound to amino acids (lysine and glycine) to improve absorption. Magnesium in this product is shown to be effective for constipation, indigestion, and treating magnesium deficiency.
What are the cordyceps in this product for?
Cordyceps are fungi traditionally used for stamina and sexual function, but the product facts show insufficient evidence to support these uses. The data actually suggests cordyceps may be ineffective for athletic performance.
Is long-term use of this product safe?
Limited safety data exist for long-term use. Rhodiola is well tolerated short-term, but long-term safety isn't well studied. Cordyceps safety data extends to one year of use, and cordyceps quality and purity vary widely between products. Talk to your doctor before taking this long-term.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Performax Forte label
Go deeper

The Full Monographs Behind Performax Forte’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Rhodiola

Interacts with 1,271 drugs

Rhodiola is an herb traditionally used to fight fatigue and help the body cope with stress. Some small studies suggest it may modestly reduce fatigue and improve mood, but the evidence is li...

Read the full Rhodiola monograph → Herb & supplement monograph

Magnesium

Interacts with 295 drugs

Magnesium is an essential mineral your body needs for muscles, nerves, blood pressure, and many other functions, and supplements are useful for preventing or correcting deficiency. Some othe...

Read the full Magnesium monograph → Herb & supplement monograph

Chromium

Interacts with 178 drugs

Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control in certain people with type 2 diabetes, b...

Read the full Chromium monograph →
Sources

Sources & How We Checked

Performax Forte's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 162 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Rhodiola 13 references
  1. Kim SH, Hyun SH, Choung SY. Antioxidative effects of Cinnamomi cassiae and Rhodiola rosea extracts in liver of diabetic mice. Biofactors 2006;26:209-19.
  2. Kwon YI, Jang HD, Shetty K. Evaluation of Rhodiola crenulata and Rhodiola rosea for management of type II diabetes and hypertension. Asia Pac J Clin Nutr 2006;15:425-32.
  3. Bystritsky A, Kerwin L, Feusner JD. A pilot study of Rhodiola rosea (Rhodax) for generalized anxiety disorder (GAD). J Altern Complement Med 2008;14:175-80.
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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