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Dietary supplement

Pico Potassium Ingredients & Drug Interactions

by RnA ReSet

Pico Potassium label
See full label image
Liquid Category: Mineral
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pico Potassium against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pico Potassium is a dietary supplement by RnA ReSet with 1 active ingredient. Its ingredients are commonly taken for preventing or treating low potassium (hypokalemia), supporting healthy blood pressure, muscle cramps.Based on those ingredients, 62 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Pico Potassium by RnA ReSet

Ask about any prescription or over-the-counter medication and we check it for interactions with Pico Potassium by RnA ReSet — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Pico Potassium by RnA ReSet

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Pico Potassium contains one active ingredient: potassium, a mineral your body needs for heart rhythm, muscle function, and blood pressure control. The supplement also includes water, citric acid, and potassium sorbate as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Essential mineral for electrolyte balance.
  • We looked for evidence on: Hypokalemia, Electrolyte imbalance, Muscle function, Blood pressure regulation.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The product facts provided do not include effectiveness data for potassium supplementation, so we can't tell you from our records whether this product works for any specific purpose.

The evidence, ingredient by ingredient Potassium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Potassium from food is safe for most people, but supplements are a different story — they can raise your blood levels dangerously, especially if you have kidney disease. The facts advise caution and medical guidance before using potassium supplements during pregnancy or while breastfeeding, though dietary potassium itself is appropriate.

When you take potassium by mouth, most people tolerate it well. Common mild side effects include belly pain, belching, diarrhea, gas, nausea, and vomiting.

Serious effects are rare but real: very high potassium can cause irregular heartbeats, heart block, low blood pressure, or confusion. Slow-release potassium tablets have been linked to bleeding ulcers in the small intestine.

Side effects, ingredient by ingredient Potassium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Potassium.
  • The most serious interaction on file is rated Moderate.
  • For scale: 62 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this supplement, check with your pharmacist if you're on potassium-sparing diuretics (water pills that save potassium), ACE inhibitors, or ARBs (blood pressure medications). All three drug types raise your risk of dangerously high potassium when combined with supplements.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Potassium supplements make sense for people whose doctor has identified a deficiency and prescribed supplementation. If you take any blood pressure medication, water pill, or have kidney disease, talk with your pharmacist or doctor before adding this product — the interaction risk is real and potentially serious.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pico Potassium, straight from the product label.

Brand RnA ReSet
Barcode (UPC) 860003751367
Net contents 8.1 Fluid Ounce(s); 240 Milliliter(s)
Market status On market
Date entered into DSLD Aug 22, 2024
DSLD ID 316327
Product type Mineral
Supplement form Liquid
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pico Potassium by RnA ReSet, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1.25 mL
Maximum serving Sizes:
1.25 mL
Servings per container
192
UPC/BARCODE
860003751367
IngredientAmount% DV
Potassium99 mg2%

Other ingredients: reverse osmosis Water, Citric Acid, Potassium Sorbate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Today's consumer requires complete formulas that meet nature's exacting standards for function and absorption. We also rely on the intelligent design of our body's biological systems and trust that when the appropriate nutrient building blocks are provided, the body will respond as it is able, to support the structure and function of cells, tissues, bones, and/or organs appropriately. Picometer size for full absorption Cardiovascular support Brain health Supports bone density Muscular function

Pico Potassium is vegan and contains no gluten, yeast, dairy, egg, soy, wheat, sugar, starch, artificial flavors, artificial colors, or animal byproducts.

Pico Potassium is vegan and contains no gluten, yeast, dairy, egg, soy, wheat, sugar, starch, artificial flavors, artificial colors, or animal byproducts.

Due to high concentration, natural crystallization can occur. This does not affect the quality of the product. Made in the USA with foreign and domestic components.

Formula

Essential mineral for electrolyte balance Positively charged stabilized ions of potassium

Dr. Dean's Pico-Ionic Minerals

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Facebook Twitter Instagram Youtube @RnAReSet

RnA ReSet formulas set a standard for a new way of approaching nutrient-based protocols. We recognize that soil depletion and processed foods actually deplete the body of essential nutrients.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Do not take undiluted. Place 1/4 teaspoon (1.25ml) serving in 4 oz of water and consume in one sitting or put into 1 liter (33.8 oz) of water and drink throughout the day. For optimum results, up to two (1/4 teaspoon) servings may be consumed daily in the same manner or as directed by your health care provider. Shake well before use. May be taken with or without food.

Brand IP Statement(s)

This is a Completement Formula

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pico Potassium by RnA ReSet label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pico Potassium label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pico Potassium by RnA ReSet

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1.25 mL Dosage formLiquid Servings per container192 Amounts shown are per serving.

Potassium

Interacts with
62 drugs
99 mg per serving Form: Potassium Chloride

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Other (inactive) ingredients: Reverse osmosis Water, Citric Acid, Potassium Sorbate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pico Potassium by RnA ReSet Drug Interactions

Want to check YOUR meds against Pico Potassium?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
62Drugs
62 Moderate

Ingredients driving the most interactions

Potassium 62

Individual Drug Interactions

The ingredients in Pico Potassium interact with 62 drugs. Click any drug to see the details.

1 of the 1 ingredient in Pico Potassium interact with drugs. Each result below shows which ingredient is responsible. Potassium

Each ingredient & the kinds of drugs it affects

For each ingredient in Pico Potassium with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
Potassium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pico Potassium, from the product label.

RnA ReSet

See all RnA ReSet products
Name
New Capstone, Inc.
Street Address
178 Cayuga Drive
City
Mooresville
State
NC
ZipCode
28117
Phone Number
1-888-577-3703
Web Address
www.rnareset.com
Pharmacist Counseling Corner

Pico Potassium by RnA ReSet: Common Questions

Does Pico Potassium by RnA ReSet interact with any medications?
Yes. Based on its ingredients, Pico Potassium has a known interaction with 62 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pico Potassium contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Pico Potassium if I'm pregnant or breastfeeding?
Potassium from food is fine during pregnancy and breastfeeding, but the facts advise using supplements only under medical guidance in both cases. Talk with your doctor or pharmacist before starting — they'll know your individual situation.
What are the most common side effects?
When taken by mouth, the most common side effects are stomach pain, belching, diarrhea, gas, nausea, and vomiting. These are generally mild, but if they're bothersome, mention them to your pharmacist.
Is this safe for someone with kidney disease?
The facts specifically caution that potassium supplements can cause dangerously high blood levels in people with kidney disease. If that's you, do not start this supplement without talking to your doctor first.
What does potassium do in your body?
Potassium is a mineral your body needs for your heart to beat steadily, your muscles to work, and your blood pressure to stay in a healthy range. It's one of several electrolytes that keep your cells and organs running.
Can high potassium cause serious problems?
Yes, though it's rare. Very high potassium levels can cause irregular heartbeats, heart block, dangerously low blood pressure, or confusion. That's why supplements need medical oversight — your doctor can monitor your levels.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pico Potassium is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pico Potassium label
Go deeper

The Full Monographs Behind Pico Potassium’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph →
Sources

Sources & How We Checked

Pico Potassium's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Potassium 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
  3. Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32. PubMed
  4. Phillips, C. O., Kashani, A., Ko, D. K., Francis, G., and Krumholz, H. M. Adverse effects of combination angiotensin II receptor blockers plus angiotensin-converting enzyme inhibitors for left ventricular dysfunction: a quantitative review of data from ra DOI
  5. Altieri, P. I., Herrero, C., Suero, R., and Ortiz, A. Bleeding duodenal ulcer in a patient taking slow-releasing potassium tablets. Bol.Asoc.Med P.R. 1977;69(8):276.
  6. Raf, L. E. Enteric-coated potassium chloride tablets and ulcer of the small intestine. Acta Chir Scand Suppl 1967;(374):1-87.
  7. Potassium chloride oral solution [package insert]. Allentown, PA: Lehigh Valley Technologies, Inc.; 2014.
  8. Potassium chloride injection [package insert]. Lake Forest, IL: Hospira Inc.; 2009.
  9. Patel RB, Tannenbaum S, Viana-Tejedor A, et al. Serum potassium levels, cardiac arrhythmias, and mortality following non-ST-elevation myocardial infarction or unstable angina: insights from MERLIN-TIMI 36. Eur Heart J Acute Cardiovasc Care 2017 Feb;6(1):1 PubMed
  10. Malta D, Arcand J, Ravindran A, Floras V, Allard JP, Newton GE. Adequate intake of potassium does not cause hyperkalemia in hypertensive individuals taking medications that antagonize the renin angiotensin aldosterone system. Am J Clin Nutr 2016 Oct;104(4 PubMed
  11. Keskin M, Kaya A, Tatlisu MA, et al. The effect of serum potassium level on in-hospital and long-term mortality in ST elevation myocardial infarction. Int J cardiol. 2016 Oct 15;221:505-10.
  12. Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad

See these in context on the Potassium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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