Plant Complete Chocolate Natural Flavor Ingredients & Drug Interactions
by ZHOU
What is this page for?
First and foremost: checking Plant Complete Chocolate Natural Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Plant Complete Chocolate Natural Flavor is a dietary supplement by ZHOU with 4 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,025 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Rice Protein, Fermented. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Plant Complete Chocolate Natural Flavor by ZHOU
Ask about any prescription or over-the-counter medication and we check it for interactions with Plant Complete Chocolate Natural Flavor by ZHOU — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Plant Complete Chocolate Natural Flavor by ZHOU
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
ZHOU Plant Complete Chocolate contains 2 active ingredients: fermented pea protein and fermented rice protein, both plant-based sources designed to support protein intake. The powder also contains inactive ingredients — cocoa, natural chocolate and vanilla flavors, Himalayan salt, guar gum, acacia gum, xanthan gum, stevia leaf extract, and natural cream flavor — which are fillers, thickeners, and flavor enhancers typical of a supplement powder.
Does it work?
Insufficient evidence
The product's two proteins have very limited evidence supporting their use. Pea protein has insufficient reliable evidence for diabetes, exercise-induced muscle soreness, high cholesterol (hyperlipidemia), high blood pressure (hypertension), or irritable bowel syndrome.
Rice protein is possibly effective for food allergies but has insufficient evidence for exercise-induced muscle soreness and muscle strength. Neither ingredient's effectiveness for general protein supplementation or muscle building is rated in our data.
How safe is it?
Well-documented data
Both pea and rice protein are generally well tolerated as food sources. However, pea protein can trigger allergic reactions in people sensitive to legumes — a case series described six children who had severe reactions (anaphylaxis, facial swelling, hives, asthma), all with a history of allergies to peanuts, tree nuts, or other legumes.
Rice protein is also generally well tolerated but has rarely been linked to intestinal inflammation (enterocolitis) in infants and young children, and allergies to rice protein itself have been reported. Neither pea nor rice protein is well studied in concentrated supplement form during pregnancy or breastfeeding — the safety data advises checking with your doctor or pharmacist before use if you're pregnant or nursing.
Meds to double-check
Moderate interaction found
If you take an ACE inhibitor (like lisinopril, enalapril, or ramipril) for high blood pressure, flag this product with your pharmacist before starting — rice protein may theoretically add to the blood pressure lowering effect, though this hasn't been proven in humans.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
If you're looking for a plant-based protein powder and you don't take ACE inhibitors for blood pressure, this product is worth considering — both proteins are food-derived and generally well tolerated. Skip it if you have a history of legume or rice allergies.
Pregnant or nursing? Check with your doctor first, since concentrated protein supplements haven't been formally studied in those situations.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Plant Complete Chocolate Natural Flavor, straight from the product label.
| Brand | ZHOU |
|---|---|
| Barcode (UPC) | 669191518611 |
| Net contents | 19.9 Ounce(s); 563.2 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Jun 20, 2024 |
| DSLD ID | 313674 |
| Product type | Amino Acid/protein |
| Supplement form | Powder |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Plant Complete Chocolate Natural Flavor by ZHOU, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 136 Calorie(s), 272 Calorie(s) | -- |
| Total Carbohydrates | 6 Gram(s) | 3% |
| Calories from Fat | 5 Calorie(s), 10 Calorie(s) | -- |
| Total Fat | 1 Gram(s) | 1% |
| Dietary Fiber | 1 Gram(s) | 4% |
| Protein | 21 Gram(s) | 46% |
| Blend | 29 Gram(s) | -- |
| Pea Protein, Fermented | 0 NP | -- |
| Rice Protein, Fermented | 0 NP | -- |
Other ingredients: Cocoa, natural Chocolate flavor, Himalayan Salt, natural Creamy Vanilla flavor, Guar Gum, Acacia Gum, Xanthan Gum, Stevia Leaf Extract, natural Cream flavor
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
Zhou Greatness by nature
Formulation
Protein that's built better.
Our formula has a PDCAAS of 1, best digestibility score.
Vegan
Optimal absorption Smooth texture
No sugar
Vegan
Supports lean muscle mass #1 Digestibility PDCAAS score Lab verified
Gluten free No added sugar
Vegan
General Statements
Plant Power+ Complete amino acid profile Supports lean muscle mass Easy to digest Vegan Whey Protein Complete amino acid profile Supports lean muscle mass Easy to digest
3 Post Best taste
#howizhou Facebook Instagram
Precautions
Warning: reproductive harm www.P65Warnings.ca.gov
Warning: Keep out of reach of children. Pregnant or nursing mothers, children under 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Do not use if safety seal is damaged or missing. Do not exceed recommended dose.
Pregnant or nursing mothers, children under 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Suggested/Recommended/Usage/Directions
Suggested use: Mix one (1) scoop (35g) into 12 fl. oz. of water and consume during or after your workout. Also enjoy mixing into hot or cold liquids, shakes, smoothies, or other favorite recipes. Use only as directed.
Tastes great in Water Shakes Smoothies Recipes
Storage
Store in a cool, dry place.
This product is packaged by weight, not volume. Settling of contents occurs over time. Fill line
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formula
Vegan protein Chocolate natural flavor 21g protein/scoop
1 scoop 21 g protein 2 scoops 42 g protein
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
Made in the USA with global ingredients
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Plant Complete Chocolate Natural Flavor by ZHOU label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Plant Complete Chocolate Natural Flavor by ZHOU
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size35 Gram(s) Dosage formPowder Servings per container8 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Dietary Fiber
Interacts with2,025 drugs
Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...
Dietary Fiber monograph & interactionsProtein
Other (inactive) ingredients: Cocoa, Natural Chocolate flavor, Himalayan Salt, Natural Creamy Vanilla flavor, Guar Gum, Acacia Gum, Xanthan Gum, Stevia Leaf Extract, Natural Cream flavor. These complete the product’s ingredient list but are not active constituents.
Plant Complete Chocolate Natural Flavor by ZHOU Drug Interactions
HelloPharmacist Interaction Report
ZHOU Plant Complete Chocolate has one documented interaction to watch for.
Rice Protein, one of the two active ingredients, may theoretically increase blood pressure lowering with ACE inhibitors (medications like lisinopril or enalapril used for high blood pressure). Laboratory and animal research suggests rice protein can inhibit the enzyme these drugs target, but this effect hasn't been proven in humans yet — so the concern is theoretical rather than confirmed.
Read the full breakdown — every affected drug type, severity by severity
Pea Protein, the other active ingredient, has no interactions documented in our data. Neither ingredient's fermented form changes the interaction picture.
Although the rice protein–ACE inhibitor interaction is only moderate in severity and unproven in real people, it's worth a quick check. Use the medication search tool on this page to confirm your exact drugs, or ask your pharmacist before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Plant Complete Chocolate Natural Flavor?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Plant Complete Chocolate Natural Flavor interact with 2,025 drugs. Click any drug to see the details.
2 of the 4 ingredients in Plant Complete Chocolate Natural Flavor interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Rice Protein, Fermented
Alogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Plant Complete Chocolate Natural Flavor — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Alogliptin, Metformin interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Plant Complete Chocolate Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Rice Protein, FermentedAce Inhibitors (aceis) Moderate
Interaction Summary
In laboratory research, hydrolyzed rice protein inhibits angiotensin-converting enzyme (ACE).
Read the full Rice Protein, Fermented + Amlodipine Besylate, Benazepril interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amlodipine Besylate, Benazepril interactionBenazeprilLotensin
How Benazepril interacts with Plant Complete Chocolate Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Rice Protein, FermentedAce Inhibitors (aceis) Moderate
Interaction Summary
In laboratory research, hydrolyzed rice protein inhibits angiotensin-converting enzyme (ACE).
Read the full Rice Protein, Fermented + Benazepril interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Benazepril interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with Plant Complete Chocolate Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Rice Protein, FermentedAce Inhibitors (aceis) Moderate
Interaction Summary
In laboratory research, hydrolyzed rice protein inhibits angiotensin-converting enzyme (ACE).
Read the full Rice Protein, Fermented + Benazepril, Hydrochlorothiazide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Benazepril, Hydrochlorothiazide interactionCanagliflozin, MetforminInvokamet
How Canagliflozin, Metformin interacts with Plant Complete Chocolate Natural Flavor — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Canagliflozin, Metformin interactionCanagliflozin, Metformin HydrochlorideInvokamet XR
How Canagliflozin, Metformin Hydrochloride interacts with Plant Complete Chocolate Natural Flavor — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberMetformin (glucophage), Oral Drugs Moderate
Interaction Summary
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Read the full Dietary Fiber + Canagliflozin, Metformin Hydrochloride interactionCaptoprilAcepril, Capoten
How Captopril interacts with Plant Complete Chocolate Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Rice Protein, FermentedAce Inhibitors (aceis) Moderate
Interaction Summary
In laboratory research, hydrolyzed rice protein inhibits angiotensin-converting enzyme (ACE).
Read the full Rice Protein, Fermented + Captopril interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Captopril interactionCaptopril, HydrochlorothiazideAcezide, Capozide
How Captopril, Hydrochlorothiazide interacts with Plant Complete Chocolate Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Rice Protein, FermentedAce Inhibitors (aceis) Moderate
Interaction Summary
In laboratory research, hydrolyzed rice protein inhibits angiotensin-converting enzyme (ACE).
Read the full Rice Protein, Fermented + Captopril, Hydrochlorothiazide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Captopril, Hydrochlorothiazide interactionCarbamazepineCarbatrol, Carnexiv, Equetro, Tegretol, Tegretol XR
How Carbamazepine interacts with Plant Complete Chocolate Natural Flavor — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Carbamazepine (tegretol) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Carbamazepine interactionCilazaprilInhibace
How Cilazapril interacts with Plant Complete Chocolate Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Rice Protein, FermentedAce Inhibitors (aceis) Moderate
Interaction Summary
In laboratory research, hydrolyzed rice protein inhibits angiotensin-converting enzyme (ACE).
Read the full Rice Protein, Fermented + Cilazapril interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Cilazapril interactionDapagliflozin Propanediol, MetforminXigduo XR
How Dapagliflozin Propanediol, Metformin interacts with Plant Complete Chocolate Natural Flavor — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Dapagliflozin Propanediol, Metformin interactionDapagliflozin, Metformin Hydrochloride, Saxagliptin HydrochlorideQternmet XR
How Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interacts with Plant Complete Chocolate Natural Flavor — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interactionDiltiazem, EnalaprilTeczem
How Diltiazem, Enalapril interacts with Plant Complete Chocolate Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Rice Protein, FermentedAce Inhibitors (aceis) Moderate
Interaction Summary
In laboratory research, hydrolyzed rice protein inhibits angiotensin-converting enzyme (ACE).
Read the full Rice Protein, Fermented + Diltiazem, Enalapril interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Diltiazem, Enalapril interactionEmpagliflozin, Linagliptin, Metformin HydrochlorideTrijardy XR
How Empagliflozin, Linagliptin, Metformin Hydrochloride interacts with Plant Complete Chocolate Natural Flavor — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Empagliflozin, Linagliptin, Metformin Hydrochloride interactionEmpagliflozin, MetforminSynjardy
How Empagliflozin, Metformin interacts with Plant Complete Chocolate Natural Flavor — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberMetformin (glucophage), Oral Drugs Moderate
Interaction Summary
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Read the full Dietary Fiber + Empagliflozin, Metformin interactionEmpagliflozin, Metformin HydrochlorideSynjardy XR
How Empagliflozin, Metformin Hydrochloride interacts with Plant Complete Chocolate Natural Flavor — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Empagliflozin, Metformin Hydrochloride interactionEnalapril MaleateEpaned, Vasotec
How Enalapril Maleate interacts with Plant Complete Chocolate Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Rice Protein, FermentedAce Inhibitors (aceis) Moderate
Interaction Summary
In laboratory research, hydrolyzed rice protein inhibits angiotensin-converting enzyme (ACE).
Read the full Rice Protein, Fermented + Enalapril Maleate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Enalapril Maleate interactionEnalapril Maleate, FelodipineLexxel
How Enalapril Maleate, Felodipine interacts with Plant Complete Chocolate Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Rice Protein, FermentedAce Inhibitors (aceis) Moderate
Interaction Summary
In laboratory research, hydrolyzed rice protein inhibits angiotensin-converting enzyme (ACE).
Read the full Rice Protein, Fermented + Enalapril Maleate, Felodipine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Enalapril Maleate, Felodipine interactionEnalapril Maleate, HydrochlorothiazideVaseretic
How Enalapril Maleate, Hydrochlorothiazide interacts with Plant Complete Chocolate Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Rice Protein, FermentedAce Inhibitors (aceis) Moderate
Interaction Summary
In laboratory research, hydrolyzed rice protein inhibits angiotensin-converting enzyme (ACE).
Read the full Rice Protein, Fermented + Enalapril Maleate, Hydrochlorothiazide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Enalapril Maleate, Hydrochlorothiazide interactionErtugliflozin, Metformin HydrochlorideSegluromet
How Ertugliflozin, Metformin Hydrochloride interacts with Plant Complete Chocolate Natural Flavor — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Ertugliflozin, Metformin Hydrochloride interactionFosinoprilMonopril
How Fosinopril interacts with Plant Complete Chocolate Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Rice Protein, FermentedAce Inhibitors (aceis) Moderate
Interaction Summary
In laboratory research, hydrolyzed rice protein inhibits angiotensin-converting enzyme (ACE).
Read the full Rice Protein, Fermented + Fosinopril interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Fosinopril interactionFosinopril, HydrochlorothiazideMonopril HCT
How Fosinopril, Hydrochlorothiazide interacts with Plant Complete Chocolate Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Rice Protein, FermentedAce Inhibitors (aceis) Moderate
Interaction Summary
In laboratory research, hydrolyzed rice protein inhibits angiotensin-converting enzyme (ACE).
Read the full Rice Protein, Fermented + Fosinopril, Hydrochlorothiazide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Fosinopril, Hydrochlorothiazide interactionGlipizide, MetforminMetaglip
How Glipizide, Metformin interacts with Plant Complete Chocolate Natural Flavor — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberMetformin (glucophage), Oral Drugs Moderate
Interaction Summary
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Read the full Dietary Fiber + Glipizide, Metformin interactionGlyburide, MetforminGlucovance
How Glyburide, Metformin interacts with Plant Complete Chocolate Natural Flavor — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Glyburide, Metformin interactionHydrochlorothiazide, LisinoprilPrinzide, Zestoretic
How Hydrochlorothiazide, Lisinopril interacts with Plant Complete Chocolate Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Rice Protein, FermentedAce Inhibitors (aceis) Moderate
Interaction Summary
In laboratory research, hydrolyzed rice protein inhibits angiotensin-converting enzyme (ACE).
Read the full Rice Protein, Fermented + Hydrochlorothiazide, Lisinopril interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Hydrochlorothiazide, Lisinopril interactionHydrochlorothiazide, MoexiprilUniretic
How Hydrochlorothiazide, Moexipril interacts with Plant Complete Chocolate Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Rice Protein, FermentedAce Inhibitors (aceis) Moderate
Interaction Summary
In laboratory research, hydrolyzed rice protein inhibits angiotensin-converting enzyme (ACE).
Read the full Rice Protein, Fermented + Hydrochlorothiazide, Moexipril interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Hydrochlorothiazide, Moexipril interactionHydrochlorothiazide, QuinaprilAccuretic
How Hydrochlorothiazide, Quinapril interacts with Plant Complete Chocolate Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Rice Protein, FermentedAce Inhibitors (aceis) Moderate
Interaction Summary
In laboratory research, hydrolyzed rice protein inhibits angiotensin-converting enzyme (ACE).
Read the full Rice Protein, Fermented + Hydrochlorothiazide, Quinapril interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Hydrochlorothiazide, Quinapril interactionLinagliptin, Metformin HydrochlorideJentadueto XR
How Linagliptin, Metformin Hydrochloride interacts with Plant Complete Chocolate Natural Flavor — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Linagliptin, Metformin Hydrochloride interactionLisinoprilPrinivil, Qbrelis, Zestril
How Lisinopril interacts with Plant Complete Chocolate Natural Flavor — through 2 ingredients. Tap an ingredient for the detail:
Rice Protein, FermentedAce Inhibitors (aceis) Moderate
Interaction Summary
In laboratory research, hydrolyzed rice protein inhibits angiotensin-converting enzyme (ACE).
Read the full Rice Protein, Fermented + Lisinopril interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Lisinopril interactionLithium Carbonate (prescription Drug)Eskalith, Lithium Carbonate
How Lithium Carbonate (prescription Drug) interacts with Plant Complete Chocolate Natural Flavor — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Lithium Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Lithium Carbonate (prescription Drug) interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Plant Complete Chocolate Natural Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Dietary Fiber
Carbamazepine (Tegretol)
Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.
Lithium
Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.
Metformin (Glucophage)
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.
Olanzapine (Zyprexa)
Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.
Digoxin (Lanoxin)
Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.
Ethinyl Estradiol
Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.
Oral Drugs
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.
Rice Protein, Fermented
Ace Inhibitors (Aceis)
In laboratory research, hydrolyzed rice protein inhibits angiotensin-converting enzyme (ACE). In animal research, the inhibition of ACE is correlated with a reduction in systolic blood pressure. So far, this effect has not been shown in humans. Theoretically, concomitant use of rice protein and ACE inhibitors may increase the risk of blood pressure becoming too low. Use with caution. ACE inhibitors include benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), and trandolapril (Mavik).
Brand information
Manufacturer and brand details for Plant Complete Chocolate Natural Flavor, from the product label.
ZHOU
See all ZHOU products- Name
- Zhou Nutrition | Zhou, Inc.
- City
- Salt Lake City
- State
- UT
- ZipCode
- 84101
- Phone Number
- 1-855-700-9468
- Web Address
- ZhouNutrition.com
Plant Complete Chocolate Natural Flavor by ZHOU: Common Questions
Does Plant Complete Chocolate Natural Flavor by ZHOU interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Plant Complete Chocolate Natural Flavor’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Black Psyllium
Interacts with 2,025 drugsBlack psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...
Read the full Black Psyllium monograph → Herb & supplement monographPea Protein
Pea protein is a plant-based protein powder made from yellow split peas, commonly used by people who want a dairy-free or vegan source of protein to support muscle and overall protein intake...
Read the full Pea Protein monograph → Herb & supplement monographRice Protein
Interacts with 23 drugsRice protein is a plant-based protein powder made from rice that offers an easy way to add protein to your diet, especially if you avoid dairy or animal products. It is generally considered...
Read the full Rice Protein monograph →Sources & How We Checked
Plant Complete Chocolate Natural Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 25 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Black Psyllium 18 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
- Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
- Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
- Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
- Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
- Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
- Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
- Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
- Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
- Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
- Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
- Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
- Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
- Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
- Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
- Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed
Pea Protein 1 reference
- Lavine E, Ben-Shoshan M. Anaphylaxis to hidden pea protein: A Canadian pediatric case series. J Allergy Clin Immunol Pract 2019;7(6):2070-1. doi: 10.1016/j.jaip.2019.02.010. PubMed
Rice Protein 6 references
- Joy JM, Lowery RP, Wilson JM, et al. The effects of 8 weeks of whey or rice protein supplementation on body composition and exercise performance. Nutr J 2013;12:86. PubMed
- Li GH, Qu MR, Wan JZ, You JM. Antihypertensive effect of rice protein hydrolysate with in vitro angiotensin I-converting enzyme inhibitory activity in spontaneously hypertensive rats. Asia Pac J Clin Nutr. 2007;16 Suppl 1:275-80.
- Reche M, Pascual C, Fiandor A, et al. The effect of a partially hydrolysed formula based on rice protein in the treatment of infants with cow's milk protein allergy. Pediatr Allergy Immunol. 2010;21(4 Pt 1):577-85. PubMed
- Amended final report on the safety assessment of Oryza sativa (rice) bran oil, Oryza sativa (rice) germ oil, rice bran acid, Oryza sativa (rice) bran wax, hydrogenated rice bran wax, Oryza sativa (rice) bran extract, Oryza sativa (rice) extract, Oryza sat
- Yasutomi M, Kosaka T, Kawakita A, et al. Rice protein-induced enterocolitis syndrome with transient specific IgE to boiled rice but not to retort-processed rice. Pediatr Int. 2014;56(1):110-2.
- Hojsak I, Kljaic-Turkalj M, Misak Z, Kolacek S. Rice protein-induced enterocolitis syndrome. Clin Nutr. 2006;25(3):533-6. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC