Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Plant Complete Chocolate Natural Flavor Ingredients & Drug Interactions

by ZHOU

Powder Category: Amino Acid/protein
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Plant Complete Chocolate Natural Flavor is a dietary supplement by ZHOU with 4 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,025 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Rice Protein, Fermented. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Plant Complete Chocolate Natural Flavor by ZHOU

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 3 active ingredients.
  • “Blend” is a proprietary blend — the label gives one combined amount (29 Gram(s)) without saying how much of each component you get.

ZHOU Plant Complete Chocolate contains 2 active ingredients: fermented pea protein and fermented rice protein, both plant-based sources designed to support protein intake. The powder also contains inactive ingredients — cocoa, natural chocolate and vanilla flavors, Himalayan salt, guar gum, acacia gum, xanthan gum, stevia leaf extract, and natural cream flavor — which are fillers, thickeners, and flavor enhancers typical of a supplement powder.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: plant protein supports lean muscle mass.
  • We looked for evidence on: Exercise-induced muscle damage, Exercise-induced muscle soreness, Muscle strength, Postoperative recovery, muscle recovery, athletic performance — and 1 related terms.
  • The closest evidence on file: Pea Protein is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle soreness (Natural Medicines).
  • Also on file: Pea Protein is rated "Insufficient Reliable Evidence To Rate" for Muscle strength, Postoperative recovery, Exercise-induced muscle damage.
  • Also on file: Rice Protein is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle soreness, Muscle strength.

The product's two proteins have very limited evidence supporting their use. Pea protein has insufficient reliable evidence for diabetes, exercise-induced muscle soreness, high cholesterol (hyperlipidemia), high blood pressure (hypertension), or irritable bowel syndrome.

Rice protein is possibly effective for food allergies but has insufficient evidence for exercise-induced muscle soreness and muscle strength. Neither ingredient's effectiveness for general protein supplementation or muscle building is rated in our data.

The evidence, ingredient by ingredient Black Psyllium Pea Protein Rice Protein

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both pea and rice protein are generally well tolerated as food sources. However, pea protein can trigger allergic reactions in people sensitive to legumes — a case series described six children who had severe reactions (anaphylaxis, facial swelling, hives, asthma), all with a history of allergies to peanuts, tree nuts, or other legumes.

Rice protein is also generally well tolerated but has rarely been linked to intestinal inflammation (enterocolitis) in infants and young children, and allergies to rice protein itself have been reported. Neither pea nor rice protein is well studied in concentrated supplement form during pregnancy or breastfeeding — the safety data advises checking with your doctor or pharmacist before use if you're pregnant or nursing.

Side effects, ingredient by ingredient Black Psyllium Pea Protein Rice Protein

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Black Psyllium, Rice Protein.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: heart-rhythm medications; lithium.
  • For scale: 2,026 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take an ACE inhibitor (like lisinopril, enalapril, or ramipril) for high blood pressure, flag this product with your pharmacist before starting — rice protein may theoretically add to the blood pressure lowering effect, though this hasn't been proven in humans.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you're looking for a plant-based protein powder and you don't take ACE inhibitors for blood pressure, this product is worth considering — both proteins are food-derived and generally well tolerated. Skip it if you have a history of legume or rice allergies.

Pregnant or nursing? Check with your doctor first, since concentrated protein supplements haven't been formally studied in those situations.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Plant Complete Chocolate Natural Flavor, straight from the product label.

Brand ZHOU
Barcode (UPC) 669191518611
Net contents 19.9 Ounce(s); 563.2 Gram(s)
Market status On market
Date entered into DSLD Jun 20, 2024
DSLD ID 313674
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Plant Complete Chocolate Natural Flavor by ZHOU, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
35 Gram(s)
Maximum serving Sizes:
70 Gram(s)
Servings per container
8
UPC/BARCODE
669191518611
IngredientAmount% DV
Calories136 Calorie(s), 272 Calorie(s)--
Total Carbohydrates6 Gram(s)3%
Calories from Fat5 Calorie(s), 10 Calorie(s)--
Total Fat1 Gram(s)1%
Dietary Fiber1 Gram(s)4%
Protein21 Gram(s)46%
Blend29 Gram(s)--
Pea Protein, Fermented0 NP--
Rice Protein, Fermented0 NP--

Other ingredients: Cocoa, natural Chocolate flavor, Himalayan Salt, natural Creamy Vanilla flavor, Guar Gum, Acacia Gum, Xanthan Gum, Stevia Leaf Extract, natural Cream flavor

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Zhou Greatness by nature

Formulation

Protein that's built better.

Our formula has a PDCAAS of 1, best digestibility score.

Vegan

Optimal absorption Smooth texture

No sugar

Vegan

Supports lean muscle mass #1 Digestibility PDCAAS score Lab verified

Gluten free No added sugar

Vegan

General Statements

Plant Power+ Complete amino acid profile Supports lean muscle mass Easy to digest Vegan Whey Protein Complete amino acid profile Supports lean muscle mass Easy to digest

3 Post Best taste

#howizhou Facebook Instagram

Precautions

Warning: reproductive harm www.P65Warnings.ca.gov

Warning: Keep out of reach of children. Pregnant or nursing mothers, children under 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Do not use if safety seal is damaged or missing. Do not exceed recommended dose.

Pregnant or nursing mothers, children under 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Suggested/Recommended/Usage/Directions

Suggested use: Mix one (1) scoop (35g) into 12 fl. oz. of water and consume during or after your workout. Also enjoy mixing into hot or cold liquids, shakes, smoothies, or other favorite recipes. Use only as directed.

Tastes great in Water Shakes Smoothies Recipes

Storage

Store in a cool, dry place.

This product is packaged by weight, not volume. Settling of contents occurs over time. Fill line

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

Vegan protein Chocolate natural flavor 21g protein/scoop

1 scoop 21 g protein 2 scoops 42 g protein

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Made in the USA with global ingredients

See for yourself

Plant Complete Chocolate Natural Flavor by ZHOU label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Plant Complete Chocolate Natural Flavor by ZHOU

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size35 Gram(s) Dosage formPowder Servings per container8 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Dietary Fiber

Interacts with
2,025 drugs
1 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions

Protein

21 Gram(s) per serving

Blend

29 Gram(s) per serving

Other (inactive) ingredients: Cocoa, Natural Chocolate flavor, Himalayan Salt, Natural Creamy Vanilla flavor, Guar Gum, Acacia Gum, Xanthan Gum, Stevia Leaf Extract, Natural Cream flavor. These complete the product’s ingredient list but are not active constituents.

Interaction report

Plant Complete Chocolate Natural Flavor by ZHOU Drug Interactions

Want to check YOUR meds against Plant Complete Chocolate Natural Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
2,025Drugs
46 Moderate 1,979 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Plant Complete Chocolate Natural Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B

Rice Protein, Fermented1 drug type · 23 drugs

Ace Inhibitors (Aceis)

In laboratory research, hydrolyzed rice protein inhibits angiotensin-converting enzyme (ACE). In animal research, the inhibition of ACE is correlated with a reduction in systolic blood pressure. So far, this effect has not been shown in humans. Theoretically, concomitant use of rice protein and ACE inhibitors may increase the risk of blood pressure becoming too low. Use with caution. ACE inhibitors include benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), and trandolapril (Mavik).

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Plant Complete Chocolate Natural Flavor, from the product label.

ZHOU

See all ZHOU products
Name
Zhou Nutrition | Zhou, Inc.
City
Salt Lake City
State
UT
ZipCode
84101
Phone Number
1-855-700-9468
Web Address
ZhouNutrition.com
Pharmacist Counseling Corner

Plant Complete Chocolate Natural Flavor by ZHOU: Common Questions

Does Plant Complete Chocolate Natural Flavor by ZHOU interact with any medications?
Yes. Based on its ingredients, Plant Complete Chocolate Natural Flavor has a known interaction with 2,025 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Plant Complete Chocolate Natural Flavor contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm allergic to peanuts?
Be cautious. Pea protein is a legume, like peanuts. A case series found that children with peanut allergies sometimes reacted to pea protein supplements. Check the label for allergen warnings and talk to your pharmacist, especially if you've had reactions to other legumes (tree nuts, chickpeas, lentils, kidney beans).
Is this safe for my infant or young child?
Rice protein has rarely been linked to intestinal inflammation in young children and infants. Talk to your pediatrician before giving this to a child, particularly under age 3.
Can I use this while pregnant?
There isn't enough data to know either way — concentrated protein supplements haven't been formally studied in pregnancy. Whole foods with pea and rice are fine, but talk with your doctor about whether a supplement form is right for you.
Does this actually help with muscle soreness or muscle building?
Our data shows insufficient evidence for either pea or rice protein to support exercise recovery or muscle strength. The product contains plant protein, but we can't say from our sources whether it's effective for those goals.
What's the fermented form do?
Fermentation is a processing method, but the facts we hold don't specify what extra benefits it offers over regular pea or rice protein.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Plant Complete Chocolate Natural Flavor is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Plant Complete Chocolate Natural Flavor label
Sources

Sources & How We Checked

Plant Complete Chocolate Natural Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 25 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Psyllium 18 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  4. Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
  5. Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
  6. Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
  7. Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
  8. Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
  9. Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
  10. Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
  11. Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
  12. Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
  13. Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
  14. Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
  15. Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
  16. Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
  17. Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
  18. Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed

See these in context on the Black Psyllium monograph →

Pea Protein 1 reference
  1. Lavine E, Ben-Shoshan M. Anaphylaxis to hidden pea protein: A Canadian pediatric case series. J Allergy Clin Immunol Pract 2019;7(6):2070-1. doi: 10.1016/j.jaip.2019.02.010. PubMed

See these in context on the Pea Protein monograph →

Rice Protein 6 references
  1. Joy JM, Lowery RP, Wilson JM, et al. The effects of 8 weeks of whey or rice protein supplementation on body composition and exercise performance. Nutr J 2013;12:86. PubMed
  2. Li GH, Qu MR, Wan JZ, You JM. Antihypertensive effect of rice protein hydrolysate with in vitro angiotensin I-converting enzyme inhibitory activity in spontaneously hypertensive rats. Asia Pac J Clin Nutr. 2007;16 Suppl 1:275-80.
  3. Reche M, Pascual C, Fiandor A, et al. The effect of a partially hydrolysed formula based on rice protein in the treatment of infants with cow's milk protein allergy. Pediatr Allergy Immunol. 2010;21(4 Pt 1):577-85. PubMed
  4. Amended final report on the safety assessment of Oryza sativa (rice) bran oil, Oryza sativa (rice) germ oil, rice bran acid, Oryza sativa (rice) bran wax, hydrogenated rice bran wax, Oryza sativa (rice) bran extract, Oryza sativa (rice) extract, Oryza sat
  5. Yasutomi M, Kosaka T, Kawakita A, et al. Rice protein-induced enterocolitis syndrome with transient specific IgE to boiled rice but not to retort-processed rice. Pediatr Int. 2014;56(1):110-2.
  6. Hojsak I, Kljaic-Turkalj M, Misak Z, Kolacek S. Rice protein-induced enterocolitis syndrome. Clin Nutr. 2006;25(3):533-6. PubMed

See these in context on the Rice Protein monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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