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Dietary supplement

Potassium Gluconate Ingredients & Drug Interactions

by New Sun

Potassium Gluconate label
See full label image
Tablet Or Pill Category: Mineral
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Potassium Gluconate against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Potassium Gluconate is a dietary supplement by New Sun with 1 active ingredient. Its ingredients are commonly taken for preventing or treating low potassium (hypokalemia), supporting healthy blood pressure, muscle cramps.Based on those ingredients, 62 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Potassium Gluconate by New Sun

Ask about any prescription or over-the-counter medication and we check it for interactions with Potassium Gluconate by New Sun — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Potassium Gluconate by New Sun

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

New Sun's Potassium Gluconate contains one active ingredient: potassium, a mineral your body needs for nerve and muscle function, including your heartbeat. The tablet also includes inactive ingredients — cellulose, stearic acid, magnesium stearate, and silica — which help hold the supplement together and make it easy to swallow.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Potassium product and its label doesn't state a use — see Potassium's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We hold no evidence data on whether potassium gluconate supplements are effective for any specific condition. Potassium is essential to your body's function, but whether supplementing helps or hurts depends entirely on your own blood potassium level and kidney health — something only your doctor can assess with a blood test.

Don't assume you need it without confirmation.

The evidence, ingredient by ingredient Potassium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Potassium from food is fine, but supplements can be risky if your kidneys don't work normally or if you're on certain medications. Most common side effects are mild gut problems — belly pain, belching, diarrhea, nausea, and vomiting.

Rarely, high potassium levels cause serious heart rhythm problems, low blood pressure, confusion, or even cardiac arrest. During pregnancy, potassium from a normal diet is appropriate, but use supplements only under medical guidance.

The same goes for breastfeeding — check with your doctor before adding a supplement.

Side effects, ingredient by ingredient Potassium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Potassium.
  • The most serious interaction on file is rated Moderate.
  • For scale: 62 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Potassium Gluconate, check with your doctor or pharmacist if you take potassium-sparing diuretics, ACE inhibitors, or angiotensin receptor blockers (ARBs). All three carry a Moderate risk of dangerously high blood potassium when combined with supplements.

These include common medications — ask your pharmacist to review your list.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Potassium supplements aren't something to take on your own hunch. If your doctor suspects you're low and sends you a prescription or recommends supplementing, that's different — but if you're on a blood pressure or heart medication, you absolutely need to confirm it's safe first.

Talk with your doctor or pharmacist before you start, especially if you have kidney disease or take a diuretic, ACE inhibitor, or ARB.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 24, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Potassium Gluconate, straight from the product label.

Brand New Sun
Barcode (UPC) 75-4
Net contents 200 Tablet(s)
Market status On market
Date entered into DSLD Aug 24, 2012
DSLD ID 12345
Product type Mineral
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Potassium Gluconate by New Sun, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
200
UPC/BARCODE
75-4
IngredientAmount% DV
Potassium99 mg3%

Other ingredients: Cellulose, Stearic Acid, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommendation: As a dietary supplement, take one tablet with each meal.

Precautions

Do not use if safety seal is missing or broken.

Keep out of reach of children.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

This product is not intended to diagnose, treat, cure, or prevent any diasease.

Warning: If you are pregnant, nursing, taking any medications, or experiencing health issues, consult your doctor before use.

General

Product No. 75-4 V 2.0

FDA Statement of Identity

Dietary Supplement

Formulation

This product does not contain: yeast, corn, wheat, gluten, soy, milk or preservatives.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Potassium Gluconate by New Sun label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Potassium Gluconate label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Potassium Gluconate by New Sun

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container200 Amounts shown are per serving.

Potassium

Interacts with
62 drugs
99 mg per serving Form: Potassium Gluconate

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Other (inactive) ingredients: Cellulose, Stearic Acid, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Potassium Gluconate by New Sun Drug Interactions

Want to check YOUR meds against Potassium Gluconate?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
62Drugs
62 Moderate

Ingredients driving the most interactions

Potassium 62

Individual Drug Interactions

The ingredients in Potassium Gluconate interact with 62 drugs. Click any drug to see the details.

1 of the 1 ingredient in Potassium Gluconate interact with drugs. Each result below shows which ingredient is responsible. Potassium

Each ingredient & the kinds of drugs it affects

For each ingredient in Potassium Gluconate with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
Potassium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Potassium Gluconate, from the product label.

New Sun

See all New Sun products
Name
New Sun
City
Hendersonville
State
NC
ZipCode
28792
Phone Number
1-800-544-0777
Web Address
www.newsun.net
Pharmacist Counseling Corner

Potassium Gluconate by New Sun: Common Questions

Does Potassium Gluconate by New Sun interact with any medications?
Yes. Based on its ingredients, Potassium Gluconate has a known interaction with 62 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Potassium Gluconate contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on a water pill?
Not without checking first. Some water pills are potassium-sparing, meaning they prevent your body from shedding potassium — adding a potassium supplement to that combination can raise your blood potassium to a dangerous level. Talk to your doctor or pharmacist about your specific medication.
What are ACE inhibitors and ARBs, and why do they matter here?
They're common blood pressure medications — lisinopril and enalapril are ACE inhibitors; losartan and valsartan are ARBs. Both types reduce how much potassium your kidneys excrete, so combining them with a potassium supplement increases your risk of hyperkalemia (dangerously high blood potassium).
What does high potassium do to me?
It can trigger serious heart rhythm problems, a drop in blood pressure, confusion, or even cardiac arrest. Most people won't notice anything until a blood test catches it — which is why your doctor needs to check your levels if you're at risk.
Is potassium gluconate safe in pregnancy?
Potassium from food is fine during pregnancy, but supplements are rated likely safe — which means check with your doctor before using one. You need personalized advice based on your own health.
What side effects might I get?
Most common are mild gut problems — belly pain, belching, diarrhea, nausea, and vomiting. Serious side effects from high potassium levels are rare but real: heart rhythm problems, low blood pressure, confusion, or cardiac arrest.
Do I need a potassium supplement?
Only if your doctor tells you so after a blood test shows you're low. Don't guess — taking it without confirmation can be risky, especially if you have kidney disease or take heart or blood pressure medication.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Potassium Gluconate is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Potassium Gluconate label
Go deeper

The Full Monographs Behind Potassium Gluconate’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph →
Sources

Sources & How We Checked

Potassium Gluconate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Potassium 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
  3. Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32. PubMed
  4. Phillips, C. O., Kashani, A., Ko, D. K., Francis, G., and Krumholz, H. M. Adverse effects of combination angiotensin II receptor blockers plus angiotensin-converting enzyme inhibitors for left ventricular dysfunction: a quantitative review of data from ra DOI
  5. Altieri, P. I., Herrero, C., Suero, R., and Ortiz, A. Bleeding duodenal ulcer in a patient taking slow-releasing potassium tablets. Bol.Asoc.Med P.R. 1977;69(8):276.
  6. Raf, L. E. Enteric-coated potassium chloride tablets and ulcer of the small intestine. Acta Chir Scand Suppl 1967;(374):1-87.
  7. Potassium chloride oral solution [package insert]. Allentown, PA: Lehigh Valley Technologies, Inc.; 2014.
  8. Potassium chloride injection [package insert]. Lake Forest, IL: Hospira Inc.; 2009.
  9. Patel RB, Tannenbaum S, Viana-Tejedor A, et al. Serum potassium levels, cardiac arrhythmias, and mortality following non-ST-elevation myocardial infarction or unstable angina: insights from MERLIN-TIMI 36. Eur Heart J Acute Cardiovasc Care 2017 Feb;6(1):1 PubMed
  10. Malta D, Arcand J, Ravindran A, Floras V, Allard JP, Newton GE. Adequate intake of potassium does not cause hyperkalemia in hypertensive individuals taking medications that antagonize the renin angiotensin aldosterone system. Am J Clin Nutr 2016 Oct;104(4 PubMed
  11. Keskin M, Kaya A, Tatlisu MA, et al. The effect of serum potassium level on in-hospital and long-term mortality in ST elevation myocardial infarction. Int J cardiol. 2016 Oct 15;221:505-10.
  12. Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad

See these in context on the Potassium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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