Probiotic Ingredients & Drug Interactions
by Genesis Pure
What is this page for?
First and foremost: checking Probiotic against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Probiotic is a dietary supplement by Genesis Pure with 2 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Probiotic Complex. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Probiotic by Genesis Pure
Ask about any prescription or over-the-counter medication and we check it for interactions with Probiotic by Genesis Pure — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Probiotic by Genesis Pure
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Genesis Pure Probiotic contains 8 active ingredients—a blend of beneficial bacteria and a prebiotic fiber. The bacterial strains are Lactobacillus plantarum, Lactobacillus acidophilus, Bifidobacterium animalis lactis, Lactobacillus salivarius, Bifidobacterium bifidum, Streptococcus thermophilus, and Lactococcus lactis; together they're meant to support gut health.
FOS Prebiotic is a plant-based fiber that feeds the good bacteria. The capsule itself contains glucose polymers, coconut oil powder, and a vegetable capsule as inactive ingredients.
Does it work?
Moderate evidence
The evidence for what this probiotic actually does varies by strain and condition. L. acidophilus and B. bifidum are both possibly effective for irritable bowel syndrome and possibly effective for antibiotic-associated diarrhea.
L. acidophilus is also possibly effective for Helicobacter pylori infection and bacterial vaginosis. B. bifidum is possibly effective for respiratory tract infections.
Streptococcus thermophilus, though, hasn't been studied enough in supplement form to establish whether it works—we don't have reliable evidence for any of the conditions listed for it. The same goes for several other claims: we simply don't have enough data to say if this product helps with those.
How safe is it?
Well-documented data
L. acidophilus and B. bifidum are generally well tolerated in healthy adults and children. That said, because they contain live microorganisms, there's a theoretical risk of infection in people with weakened immune systems—those folks should talk to their doctor first.
Uncommon side effects with L. acidophilus or combinations of probiotics include stomach discomfort, bloating, gas, diarrhea, and vomiting. Streptococcus thermophilus is also generally well tolerated in healthy people, though again, anyone immunocompromised should check with their doctor.
Rare cases of serious infection (bacteremia, sepsis) have been reported with probiotic use, but these occur almost exclusively in critically ill patients or those with central lines—not in otherwise healthy people. For pregnancy, L. acidophilus, B. bifidum, and S. thermophilus are all rated possibly safe, though you should discuss probiotic supplements with your doctor or pharmacist for personalized advice.
Data on lactation aren't on file for these ingredients.
Meds to double-check
Moderate interaction found
If you take any antibiotic drugs, timing is key: L. acidophilus and B. bifidum can lose effectiveness if you take them at the same time as antibiotics. Ask your pharmacist to help you space them out by a few hours.
Check your full medication list with your doctor or pharmacist before starting, since we hold data on only some of the ingredients in this product.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Genesis Pure Probiotic may help with certain gut issues and is generally well tolerated in healthy adults. If you're on antibiotics, you'll want to separate the timing so the antibiotic and probiotic don't interfere with each other.
Anyone with a weakened immune system, or anyone taking medications, should check with their own doctor or pharmacist before starting this—especially if you're pregnant or nursing.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Probiotic, straight from the product label.
| Brand | Genesis Pure |
|---|---|
| Net contents | 60 Vegetarian Capsules |
| Market status | On market |
| Date entered into DSLD | Aug 23, 2019 |
| DSLD ID | 206011 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Probiotic by Genesis Pure, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Lactobacillus plantarum | 0 NP | -- |
| Lactobacillus acidophilus | 0 NP | -- |
| Bifidobacterium animalis lactis | 0 NP | -- |
| Lactobacillus salivarius | 0 NP | -- |
| Bifidobacterium bifidum | 0 NP | -- |
| Streptococcus thermophilus | 0 NP | -- |
| Lactococcus lactis | 0 NP | -- |
| Probiotic Complex | 500 mg | -- |
| FOS Prebiotic | 250 mg | -- |
Other ingredients: Glucose Polymers, Coconut Oil powder, Vegetable Capsule
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Recommended use: Take one capsule on an empty stomach, in the morning and evening. May take more under the guidance of a physician.
Storage
Keep in a cool, dry place.
Precautions
Not recommended for children.
If you are pregnant, nursing, taking a prescription medication, or have a medical condition, consult a physician before using this product.
FDA Disclaimer Statement
These statements have not been evaluated bu the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Brand IP Statement(s)
2016 Genesis Pure. All rights reserved.
Formula
As a everyday essential product, Genesis Pure Probiotic: Delivers seven strains of good bacteria, which support digestive health. One capsule contains two billion colony forming units (CFU). Combines multiple strains of health-promoting Bifidobacteria, Lactobacilli and other beneficial cultures to help maintain a healthy digestive balance to enhance digestion and aid in regularity. Contains prebiotics to help foster beneficial bacteria growth.
General Statements
Helps maintain normal intestinal microflora. Helps relieve occasional constipation. Helps support healthy immune function. Use Probiotic upon completion of Liquid or Capsule Cleanse.
Formulation
Dairy free, Soy free, Vegan, all natural.
Dairy free, Soy free, Vegan, all natural
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Probiotic by Genesis Pure label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Probiotic by Genesis Pure
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Probiotic Complex
Interacts with182 drugs
Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...
Probiotic Complex monograph & interactions- › Lactobacillus plantarum
- › Lactobacillus acidophilus
- › Bifidobacterium animalis lactis
- › Lactobacillus salivarius
- › Bifidobacterium bifidum
- › Streptococcus thermophilus
- › Lactococcus lactis
FOS Prebiotic
Other (inactive) ingredients: Glucose Polymers, Coconut Oil powder, Vegetable Capsule. These complete the product’s ingredient list but are not active constituents.
Probiotic by Genesis Pure Drug Interactions
HelloPharmacist Interaction Report
Genesis Pure Probiotic may interact with medications through its Lactobacillus acidophilus and Bifidobacterium bifidum content.
The most serious documented concern is a Moderate interaction with antibiotic drugs: since these probiotic strains contain live organisms, antibiotics taken at the same time might kill a significant portion of them, reducing the probiotic's effectiveness. Altogether, these interactions span 182 individual medications.
Read the full breakdown — every affected drug type, severity by severity
Both L. acidophilus and B. bifidum share the same antibiotic interaction, so if you're on any antibiotic, timing matters. The solution is straightforward — separate when you take them.
Your doctor or pharmacist can help you space them out (typically a few hours apart) so the antibiotic does its job and the probiotic survives to do its own.
We couldn't check several other ingredients in this product—Lactobacillus plantarum, Bifidobacterium animalis lactis, Lactobacillus salivarius, Lactococcus lactis, and FOS Prebiotic—because we don't hold data on them. That doesn't mean they interact; it just means we can't confirm either way.
Streptococcus thermophilus showed no interactions in our data. Use the interaction checker on this page with your specific medications to confirm there's nothing else to watch for.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Probiotic?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Probiotic interact with 182 drugs. Click any drug to see the details.
1 of the 2 ingredients in Probiotic interact with drugs. Each result below shows which ingredient is responsible. Probiotic Complex
AmikacinAmikin, Arikayce
How Amikacin interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Amikacin interactionProbiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Amikacin interactionAmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more
How Amoxicillin interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Probiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Amoxicillin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Amoxicillin interactionAmoxicillin VeterinaryBiomox
How Amoxicillin Veterinary interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Probiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Amoxicillin Veterinary interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Amoxicillin Veterinary interactionAmoxicillin, Clavulanate PotassiumAugmentin, Augmentin '125/31 SF', Augmentin '250/62 SF', Augmentin XR, Augmentin-Duo 400/57, Clavulin
How Amoxicillin, Clavulanate Potassium interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Probiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Amoxicillin, Clavulanate Potassium interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Amoxicillin, Clavulanate Potassium interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Probiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Amphotericin, Tetracycline interactionProbiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Amphotericin, Tetracycline interactionAmpicillinOmnipen, Omnipen-N, Penbritin, Principen, Rimacillin
How Ampicillin interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Probiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Ampicillin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Ampicillin interactionAmpicillin, SulbactamUnasyn
How Ampicillin, Sulbactam interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Probiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Ampicillin, Sulbactam interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Ampicillin, Sulbactam interactionAvibactam Sodium, CeftazidimeAvycaz
How Avibactam Sodium, Ceftazidime interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Avibactam Sodium, Ceftazidime interactionProbiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Avibactam Sodium, Ceftazidime interactionAzithromycinAzasite, Zithromax, Zmax
How Azithromycin interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Probiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Azithromycin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Azithromycin interactionAztreonamAzactam
How Aztreonam interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Aztreonam interactionProbiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Aztreonam interactionBacampicillinPenglobe
How Bacampicillin interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Probiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Bacampicillin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Bacampicillin interactionBacitracinBaci-IM, Baciguent, Bacitracin Ointment
How Bacitracin interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Probiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Bacitracin interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Bacitracin interactionBenznidazoleBenznidazole
How Benznidazole interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Benznidazole interactionProbiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Benznidazole interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Probiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionCapreomycinCapastat
How Capreomycin interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Capreomycin interactionProbiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Capreomycin interactionCarbenicillin Indanyl SodiumGeocillin
How Carbenicillin Indanyl Sodium interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Probiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Carbenicillin Indanyl Sodium interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Carbenicillin Indanyl Sodium interactionCefaclorCeclor, Ceclor CD
How Cefaclor interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Probiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Cefaclor interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefaclor interactionCefadroxilCef-Tab, Duricef, Ultracef
How Cefadroxil interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Probiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Cefadroxil interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefadroxil interactionCefamandoleMandol
How Cefamandole interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Probiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Cefamandole interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefamandole interactionCefazolinAncef
How Cefazolin interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefazolin interactionProbiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Cefazolin interactionCefdinirOmnicef
How Cefdinir interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Probiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Cefdinir interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefdinir interactionCefditoren PivoxilSpectracef
How Cefditoren Pivoxil interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Probiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Cefditoren Pivoxil interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefditoren Pivoxil interactionCefepimeMaxipime
How Cefepime interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefepime interactionProbiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Cefepime interactionCefiderocol Sulfate TosylateFetroja
How Cefiderocol Sulfate Tosylate interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Probiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Cefiderocol Sulfate Tosylate interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefiderocol Sulfate Tosylate interactionCefiximeSuprax
How Cefixime interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Probiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Cefixime interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefixime interactionCefmetazoleZefazone
How Cefmetazole interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Probiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Cefmetazole interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefmetazole interactionCefonicidMonocid
How Cefonicid interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefonicid interactionProbiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Cefonicid interactionCefoperazoneCefobid
How Cefoperazone interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Probiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Cefoperazone interactionBifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefoperazone interactionCefotaximeClaforan
How Cefotaxime interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full Bifidobacterium Bifidum + Cefotaxime interactionProbiotic ComplexAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Complex + Cefotaxime interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Probiotic with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Probiotic Complex
Antibiotic Drugs
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.
Brand information
Manufacturer and brand details for Probiotic, from the product label.
Genesis Pure
See all Genesis Pure products- Name
- Genesis Pure
- Street Address
- 7164 Technology Drive, Suite 100
- City
- Frisco
- State
- TX
- ZipCode
- 75033
- Phone Number
- (866) 535-5888
- Web Address
- [email protected]
Probiotic by Genesis Pure: Common Questions
Does Probiotic by Genesis Pure interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this while I'm on antibiotics?
Does this actually help with IBS or diarrhea?
What are the most common side effects?
Is this safe if I'm pregnant?
What does the FOS Prebiotic ingredient do?
Should someone with a weak immune system take this?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Probiotic is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Probiotic’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lactobacillus Acidophilus
Interacts with 182 drugsLactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...
Read the full Lactobacillus Acidophilus monograph → Herb & supplement monographBifidobacterium Bifidum
Interacts with 182 drugsBifidobacterium bifidum is a 'friendly' bacteria (probiotic) that naturally lives in the human gut and is taken to support digestion and gut balance. Some evidence suggests probiotics may he...
Read the full Bifidobacterium Bifidum monograph → Herb & supplement monographStreptococcus Thermophilus
Streptococcus thermophilus is a friendly bacterium used as a probiotic, often combined with other strains in yogurt and supplements. It is generally well tolerated in healthy people and may...
Read the full Streptococcus Thermophilus monograph →Sources & How We Checked
Probiotic's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 43 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lactobacillus Acidophilus 15 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
- Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
- Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
- Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
- Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
- Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
- Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.
See these in context on the Lactobacillus Acidophilus monograph →
Bifidobacterium Bifidum 7 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Rerksuppaphol S, Rerksuppaphol L. Randomized controlled trial of probiotics to reduce common cold in schoolchildren. Pediatr Int. 2012;54(5):682-7. PubMed
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
See these in context on the Bifidobacterium Bifidum monograph →
Streptococcus Thermophilus 21 references
- Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. PubMed
- Tynkkynen S, Singh KV, Varmanen P. Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 1998;41:195-204. PubMed
- Klein G, Zill E, Schindler R, et al. Peritonitis associated with vancomycin-resistant Lactobacillus rhamnosus in a continuous ambulatory peritoneal dialysis patient; organism identification, antibiotic therapy, and case report. J Clin Microbiol 1998;36:
- Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. PubMed
- Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. DOI
- Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60.
- MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed
- Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005;115:178-81.
- De Groote MA, Frank DN, Dowell E, et al. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatr Infect Dis J 2005;24:278-80. PubMed
- Vahabnezhad E, Mochon AB, Wozniak LJ, Ziring DA. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. J Clin Gastroenterol. 2013;47(5):437-9. PubMed
- Dolatkhah N, Hajifaraji M, Abbasalizadeh F, Aghamohammadzadeh N, Mehrabi Y, Abbasi MM. Is there a value for probiotic supplements in gestational diabetes mellitus? A randomized clinical trial. J Health Popul Nutr. 2015;33:25. PubMed
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Sendil S, Shrimanker I, Mansoora Q, Goldman J, Nookala VK. Lactobacillus rhamnosus bacteremia in an immunocompromised renal transplant patient. Cureus. 2020;12(2):e6887. PubMed
- Albarillo FS, Shah U, Joyce C, Slade D. Lactobacillus rhamnosus Infection: A single-center 4-year descriptive analysis. J Glob Infect Dis. 2020;12(3):119-123. PubMed
- Pasala S, Singer L, Arshad T, Roach K. Lactobacillus endocarditis in a healthy patient with probiotic use. IDCases. 2020;22:e00915. PubMed
- Agrawal S, Tuchman ES, Bruce MJ, Theodorou ME. Fatal Lactobacillus endocarditis in a patient with transcatheter aortic valve replacement. BMJ Case Rep. 2020;13(11):e236835.
- Antoun M, Hattab Y, Akhrass FA, Hamilton LD. Uncommon pathogen, Lactobacillus, causing infective endocarditis: Case report and review. Case Rep Infect Dis. 2020;2020:8833948. PubMed
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Franko B, Vaillant M, Recule C, Vautrin E, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics. Med Mal Infect. 2013;43(4):171-3. PubMed
- Campbell RE, Miller A, Afroze A. Native valve endocarditis secondary to Lactobacillus paracasei bacteremia. Consultant. 2020;60(9):27-8. DOI
- Kato K, Funabashi N, Takaoka H, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics with advanced and severe bicuspid aortic valve stenosis complicated with diffuse left ventricular mid-layer fibrosis. Int J Cardiol. 2016;224:157-161. PubMed
See these in context on the Streptococcus Thermophilus monograph →
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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