Major interaction on record — check this product against your medications before combining. Based on 16 of 23 ingredients. Check your meds →

Dietary supplement

PureGreen Protein Vanilla Ingredients & Drug Interactions

Q: Does PureGreen Protein Vanilla by Vibrant Health interact with any medications?

Yes. Based on its ingredients, PureGreen Protein Vanilla has a known interaction with 2,214 medications, including 21 rated major. Use the checker to see how it interacts with a specific drug.

Q: How can one product interact with so many drugs?

PureGreen Protein Vanilla contains 23 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.

Q: Where does this information come from?

The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.

Q: Does this product contain any fillers or additives?

The product facts show no inactive other ingredients listed, so no fillers or binders are noted in the data we hold. The 20 active ingredients include the protein sources, amino acids, vitamins, minerals, enzymes, and natural flavoring.

Q: Is this safe to use if I'm pregnant?

Calcium and potassium from food are considered safe in pregnancy. However, vitamin A at high doses is possibly unsafe in pregnancy because it can cause birth defects. Since this product contains added vitamin A, you should talk with your doctor or midwife before using it — they can tell you whether the amount is appropriate for your situation.

Q: Can I use this if I'm taking blood pressure medication?

The sodium in this product can potentially reduce how well blood pressure medications work, and potassium can raise levels of certain blood pressure drugs to dangerous heights. You need to discuss this specific product with your doctor or pharmacist before starting it — they know your exact medication and can advise whether it's safe for you.

Q: Will this help me build muscle?

The product contains multiple protein sources (pea, alfalfa, and rice) designed to support protein intake, which is needed for muscle maintenance and growth. However, the evidence we hold on these specific ingredients for muscle strength and exercise recovery is Insufficient to Rate their effectiveness — the benefit depends on your overall diet, training, and individual factors.

Q: What should I watch for if I start this product?

Most people tolerate the ingredients at recommended doses. Watch for digestive upset (nausea, diarrhea, bloating, constipation), headache, or skin reactions. If you experience unusual symptoms or if you take medications, stop and contact your pharmacist or doctor to make sure it is not interacting with your drugs.

Q: Is there vitamin A in this product, and is it safe?

Yes, this product contains vitamin A, which is Effective for vitamin A deficiency and Possibly Effective for aging skin. At normal recommended amounts, it is safe. However, vitamin A builds up in your body, so high doses can be toxic and cause serious liver damage. High-dose vitamin A is possibly unsafe in pregnancy. Check the label for the amount and discuss it with your doctor, especially if you are pregnant or take other supplements containing vitamin A.

by Vibrant Health

See full label image

Powder Category: Other Combinations

Most serious interaction: Major

Clinical methodology reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Sep 16, 2026 · Label data from the NIH DSLD

What is this page for?

First and foremost: checking PureGreen Protein Vanilla against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

PureGreen Protein Vanilla is a dietary supplement by Vibrant Health with 23 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,214 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Dietary Fiber, Alfalfa Protein, Vitamin A. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against PureGreen Protein Vanilla by Vibrant Health

Ask about any prescription or over-the-counter medication and we check it for interactions with PureGreen Protein Vanilla by Vibrant Health — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds

AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI

Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of PureGreen Protein Vanilla by Vibrant Health

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure

Ingredient Transparency · database check

Full

Every active ingredient lists its own amount on the label.

Why this rating?

The label discloses an exact amount for 21 of its 21 active ingredients.
No proprietary blends here — you can verify the dose of every single component.

PureGreen Protein Vanilla contains 20 ingredients, including protein from pea, alfalfa, and rice sources, along with added electrolytes (sodium and potassium) and essential micronutrients. Key active ingredients are calcium, iron, vitamin A, and vitamin B12.

The product also includes amino acids (methionine, valine, threonine, and lysine), digestive enzymes (protease and alpha-galactosidase), spirulina powder, and natural flavoring. There are no inactive other ingredients listed.

Does it work?

Not established

Evidence for Intended Use · database check

By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?

The label markets this product for: muscle synthesis and endurance support.
We looked for evidence on: Athletic performance, muscle recovery, protein synthesis, muscular strength.
The closest evidence on file: Iron is rated "Possibly Ineffective" for Athletic performance (Natural Medicines).
Also on file: Lysine is rated "Insufficient Reliable Evidence To Rate" for Athletic performance.
Also on file: Blue-green Algae is rated "Insufficient Reliable Evidence To Rate" for Athletic performance.

The evidence for this product's individual ingredients is mixed. Calcium is Effective for supporting bone health and managing high potassium levels, and Likely Effective for osteoporosis.

Iron is Effective for iron deficiency anemia and Possibly Effective for heart failure. Vitamin A is Effective for vitamin A deficiency and Possibly Effective for skin aging and measles.

Vitamin B12 is Effective for B12 deficiency and cyanide poisoning. The protein sources (pea, alfalfa, and rice) and other amino acids lack established evidence for most conditions in our data — their effectiveness ratings are listed as Insufficient Reliable Evidence to Rate.

Spirulina shows Possibly Effective evidence for high blood pressure but Insufficient Evidence for most other uses.

The evidence, ingredient by ingredient Black Psyllium Sodium Potassium Calcium Iron Vitamin A Vanilla Methionine

How safe is it?

Well-documented data

Safety Information · database check

Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?

We hold adverse-effect (side-effect) data for 16 of the 16 matched ingredients.
Pregnancy & breastfeeding safety ratings cover 16 of 16.
General safety write-ups exist for 16 of 16.
Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most ingredients in this product are generally well tolerated at recommended doses. Sodium and potassium must be monitored closely because excess amounts can cause serious cardiovascular and kidney problems, especially in people with existing conditions — normal dietary amounts are fine, but avoid supplemental overload.

Calcium is generally safe at recommended levels but can cause constipation and, at very high doses, kidney stones. Iron commonly causes mild digestive upset (constipation, nausea, diarrhea) at typical doses and is well tolerated when taken appropriately.

Vitamin A is safe below the upper limit but toxic at very high doses, potentially causing liver damage and birth defects — high doses should be avoided, especially in pregnancy. Vitamin B12 is very safe with no established upper limit.

Spirulina and alfalfa may cause digestive upset (bloating, diarrhea, nausea) and carry contamination risks with some commercial products. Threonine may cause headache and minor gastrointestinal upset.

Lysine is generally well tolerated but may cause abdominal pain and diarrhea at high doses.

Side effects, ingredient by ingredient Black Psyllium Sodium Potassium Calcium Iron Vitamin A Vanilla Methionine

Meds to double-check

Major interaction found

Known Interaction Concern · database check

Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?

12 of the 16 matched ingredients can interact with medications — Alfalfa, Black Psyllium, Lysine, Calcium, Potassium, among others.
The most serious interaction on file is rated Major.
Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; heart-rhythm medications; lithium; Parkinson's medications.
For scale: 2,215 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your pharmacist or doctor if you take HIV medications (especially dolutegravir or elvitegravir), blood thinners like warfarin, blood pressure medications (ACE inhibitors, ARBs, or others), diabetes drugs, lithium, tetracycline antibiotics, thyroid medication (levothyroxine), or immunosuppressants. The sodium and potassium content means this product is not appropriate for people on certain diuretics or with kidney disease without medical clearance.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

This is a multi-nutrient protein powder designed to provide protein, electrolytes, and vitamins — potentially useful for people seeking a convenient protein source or micronutrient supplementation. However, because it contains sodium, potassium, calcium, and iron alongside medications, and because several ingredients interact with common drugs, you should review your complete medication list with your doctor or pharmacist before starting.

Anyone with kidney disease, heart disease, blood pressure issues, or taking blood thinners, diabetes medications, or HIV drugs especially needs to discuss this product first with their own healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 17 of 21 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about PureGreen Protein Vanilla, straight from the product label.

Brand	Vibrant Health
Barcode (UPC)	074306800701
Net contents	470 Gram(s); 16.58 oz.
Market status	On market
Date entered into DSLD	Mar 25, 2015
DSLD ID	43081
Product type	Other Combinations
Supplement form	Powder
Dietary claims / uses	Nutrient, All Other, Structure/Function
Intended target group(s)	Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free

From the label

Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for PureGreen Protein Vanilla by Vibrant Health, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):

Adults and children 4 or more years of age

Minimum serving Sizes:

31.34 Gram(s)

Maximum serving Sizes:

31.34 Gram(s)

Servings per container

UPC/BARCODE

074306800701

Ingredient	Amount	% DV
Calories	120 {Calories}	--
Total Carbohydrates	6.61 Gram(s)	2%
Sugar	0.6 Gram(s)	--
Calories from Fat	13.9 {Calories}	--
Dietary Fiber	1.81 Gram(s)	7%
Protein	20 Gram(s)	40%
Sodium	178 mg	7%
Potassium	145 mg	4%
Calcium	389 mg	39%
Iron	11.7 mg	65%
Vitamin A	6110 IU	122%
Total Fat	1.54 Gram(s)	2%
natural Vanilla flavor	1.5 Gram(s)	--
L-Methionine	370 mg	--
L-Valine	510 mg	--
L-Threonine	590 mg	--
L-Lysine	730 mg	--
Vitamin B12	250 mcg	4167%
Alpha-Galactosidase	300 GALU	--
Protease	20000 HUT	--
Protease	75 SAPU	--
natural Almond flavor	0.2 Gram(s)	--
Yellow Pea Protein	13.19 Gram(s)	--
Spirulina powder	2.2 Gram(s)	--
Alfalfa Protein	6.59 mg	--
Rice Protein	4.4 Gram(s)	--
natural Sweetener	0.9 Gram(s)	--

Tap any ingredient to jump to its full detail below.

Label statements

These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.

General Statements

WHERE SCIENCE & NATURE MEET

Comprehensive Plant Proteins Balanced for Rapid & Complete Absorption

Amino Acid Ratio of Human Muscle

Tastes Great!

An Alkalinizing, Nutrient Dense, Plant Protein Complex* from 13.7 lbs of Vegetables with All Branched-Chain Aminos (BCAAs) to Improve Muscle Synthesis & Endurance*

CLINICALLY FORMULATED*

LOOK WHAT'S INSIDE 14 Ingredient Formula

Typical Profile of Essential Amino Acids Leucine 2 g Valine 1.8 g Lysine 1.7 g Arginine (semi-essential) 1.47 g Isoleucine 1.2 g Threonine 1.18 g Phenylalanine 0.92 g Tryptophan 0.65 g Methionine 0.59 g

MADE IN THE USA SINCE 1992

* Formulated by Mark Timon, Founder, Vibrant Health MS Clinical Nutrition

PLEASE RECYCLE THIS CONTAINER

PureGreen Protein: The Smart Alternative Most of today’s meats and dairy products carry dangerous amounts of growth stimulant, antibiotic, and hormone contaminants. Plant proteins are free of those harmful substances. They can be used in place of animal protein, but only if all the essential amino acids are present in the right combination. Nearly all plant proteins lack one or more essential amino acids, or contain so little of one that it is as if the amino acid were absent. But a few plant proteins fare better. Pea protein ranks highly with an amino acid ratio roughly approximating human muscle. Spirulina protein and rice protein contain good amounts of all essential amino acids.*

Branched-Chain Amino Acids Valine, Leucine and Isoleucine are the Branched-Chain Amino Acids (BCAAs). They are responsible for muscle synthesis and repair. 75% of all BCAAs ingested by infants go to muscle synthesis. Athletes need them too for muscle building and endurance. BCAAs can be consumed for fuel during prolonged exercise. As they are lost, more tryptophan metabolites enter the brain, thereby raising serotonin levels. Elevated serotonin during exercise creates a sense of fatigue. Supplemental BCAAs may reduce perceived exertion and mental fatigue during prolonged exercise by supporting normal BCAA: tryptophan ratios, thereby limiting increased synthesis of serotonin in the brain.*

Also available in Chocolate, Mixed Berry and Natural.

Smoothie Recipe 1 serving of PureGreen Protein Vanilla 1 1/2 cups cold water 1 banana 1 cup banana or vanilla yogurt 1 tbsp. creamy nut butter of choice Combine all ingredients, blend until smooth and Enjoy!

General

Version 2.0

Formula

20g of Protein per Serving Added B12 & Enzymes

Non-GMO protein from Pea, Rice, Spirulina and Alfalfa are joined with four free amino acids (Lysine, Methionine, Threonine and Valine) to create the first all vegetable protein ideally balanced for human compatibility.*

Formulation

VEGAN/VEGETARIAN

GLUTEN FREE/SOY FREE

FULL DISCLOSURE LABEL - NO PROPRIETARY BLENDS

FDA Statement of Identity

DIETARY SUPPLEMENT

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevents any disease.

Brand IP Statement(s)

Matches Human Muscle By combining a variety of plant proteins in correct amounts, and adding a few select free amino acids, we created a pure vegetable protein with an amino acid ratio that surpasses albumin and whey proteins, and is nearly equal to that of human muscle tissue. We call it PureGreen Protein(TM).

Suggested/Recommended/Usage/Directions

Directions As a dietary supplement, once each day - or more often if you would like - mix one level scoop (enclosed) of PureGreen Protein into 8 ounces of your favorite juice, rice or almond beverage, or water. Stir briskly. Drink and prosper.

Storage

Store in a cool, dry place.

Precautions

Keep out of reach of children.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

PureGreen Protein Vanilla by Vibrant Health label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)

What’s inside

The Ingredients in PureGreen Protein Vanilla by Vibrant Health

These are the 23 active ingredients this product is made of. Select any to open its full monograph.

Serving size31.34 Gram(s) Dosage formPowder Servings per container15 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

0.6 Gram(s) per serving

Dietary Fiber

Interacts with
2,025 drugs

1.81 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions

Protein

20 Gram(s) per serving

Sodium

Interacts with
205 drugs

178 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Potassium

Interacts with
62 drugs

145 mg per serving

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Calcium

Interacts with
168 drugs

389 mg per serving

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet f...

Calcium monograph & interactions

Iron

Interacts with
80 drugs

11.7 mg per serving

Iron is an essential mineral your body needs to make hemoglobin and carry oxygen in the blood. Supplements are mainly useful for treating or preventin...

Iron monograph & interactions

Vitamin A

Interacts with
387 drugs

6110 IU per serving Form: Beta-Carotene

Vitamin A is an essential nutrient important for vision, skin, immune function, and growth. Most people get enough from a balanced diet, and supplemen...

Vitamin A monograph & interactions

Natural Vanilla flavor

No known
interactions

1.5 Gram(s) per serving

Vanilla is best known and very safe as a food flavoring, and small amounts used in cooking are not a concern for most people. As a health supplement,...

Natural Vanilla flavor monograph & interactions

L-Methionine

No known
interactions

370 mg per serving

Methionine is an essential amino acid that your body needs for protein building and many basic chemical reactions. Most people get enough from a norma...

L-Methionine monograph & interactions

L-Valine

510 mg per serving

L-Threonine

Interacts with
3 drugs

590 mg per serving

Threonine is an essential amino acid your body needs but cannot make, so you must get it from food or supplements. Most people get plenty from a norma...

L-Threonine monograph & interactions

L-Lysine

Interacts with
1 drug

730 mg per serving

Lysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to t...

L-Lysine monograph & interactions

Vitamin B12

Interacts with
20 drugs

250 mcg per serving Form: Methylcobalamin

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very h...

Vitamin B12 monograph & interactions

Alpha-Galactosidase

300 GALU per serving

Protease

No known
interactions

20000 HUT per serving Form: Aspergillus oryzae

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...

Protease monograph & interactions

Protease

No known
interactions

75 SAPU per serving Form: Aspergillus niger

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...

Protease monograph & interactions

Natural Almond flavor

0.2 Gram(s) per serving

Yellow Pea Protein

No known
interactions

13.19 Gram(s) per serving

Pea protein is a plant-based protein powder made from yellow split peas, commonly used by people who want a dairy-free or vegan source of protein to s...

Yellow Pea Protein monograph & interactions

Spirulina powder

Interacts with
327 drugs

2.2 Gram(s) per serving

Blue-green algae are nutrient-rich aquatic microorganisms (such as spirulina and Klamath Lake algae) taken as a supplement for energy, nutrition, and...

Spirulina powder monograph & interactions

Alfalfa Protein

Interacts with
583 drugs

6.59 mg per serving

Alfalfa is a nutrient-rich legume that people use for high cholesterol, menopause symptoms, and general wellness, but solid human evidence for most of...

Alfalfa Protein monograph & interactions

Rice Protein

Interacts with
23 drugs

4.4 Gram(s) per serving

Rice protein is a plant-based protein powder made from rice that offers an easy way to add protein to your diet, especially if you avoid dairy or anim...

Rice Protein monograph & interactions

Natural Sweetener

0.9 Gram(s) per serving Form: Luo Han Guo

HelloPharmacist.com · Pharmacist card

PureGreen Protein Vanilla

by Vibrant Health · label dated Mar 25, 2015

Scan for the full live report

Known drug interactions: 2,214 medications — most serious rated major

Active ingredients

Sugar, Dietary Fiber, Protein, Sodium, Potassium, Calcium, Iron, Vitamin A, Natural Vanilla flavor, L-Methionine, L-Valine, L-Threonine, …

Most serious documented interactions

Acitretin — Major (via Vitamin A)
Alitretinoin — Major (via Vitamin A)
Bexarotene — Major (via Vitamin A)

Full interaction list, ingredient monographs & live checker: https://hellopharmacist.com/drug-supplement-interactions/supplements/puregreen-protein-vanilla-by-vibrant-health-151371
Printed · Educational information only — not medical advice. Confirm against the physical product label and with your pharmacist.

Interaction report

PureGreen Protein Vanilla by Vibrant Health Drug Interactions

PureGreen Protein Vanilla — Vibrant Health · HelloPharmacist interaction report
Active ingredients: Sugar, Dietary Fiber, Protein, Sodium, Potassium, Calcium, Iron, Vitamin A, natural Vanilla flavor, L-Methionine, L-Valine, L-Threonine, L-Lysine, Vitamin B12, Alpha-Galactosidase, …
Source label: Mar 25, 2015 · Printed · HelloPharmacist.com
Educational information only — not medical advice. Confirm against the physical product label and with your pharmacist.

HelloPharmacist Interaction Report

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Clinical methodology reviewed by Dr. Brian Staiger, PharmD, BCPS · Last generated Sep 10, 2026

23 active ingredients 12 with known interactions 2,214 medications covered

PureGreen Protein Vanilla by Vibrant Health contains several ingredients with documented medication interactions.

The most serious concern is through its calcium content, which can significantly reduce blood levels of two HIV integrase inhibitors (dolutegravir and elvitegravir) — both classified as Major interactions — and can cause a dangerous reaction if given intravenously alongside the antibiotic ceftriaxone. Additionally, through sodium, potassium, iron, vitamin A, threonine, lysine, spirulina, and alfalfa, this product interacts with a range of common medications.

Read the full breakdown — every affected drug type, severity by severity

Sodium poses Moderate risks with blood pressure medications, steroids, lithium, and several other drug types by raising sodium levels or interfering with how your body handles the medication. Potassium carries Moderate risk with blood pressure drugs (ACE inhibitors and ARBs) and potassium-sparing diuretics through the risk of dangerously high potassium levels.

Iron reduces absorption of antibiotics, thyroid medication, and several other drugs if taken at the same time. Vitamin A at high doses poses Moderate risk with blood thinners and tetracycline antibiotics.

Threonine theoretically interferes with NMDA antagonists (a Major interaction). Lysine has a Minor documented interaction with certain gut medications.

Spirulina and alfalfa each carry Moderate risks with blood thinners, diabetes drugs, and immune-suppressing medications. Altogether, these interactions span 1,067 individual medications.

We could not check L-valine, natural almond flavor, or natural sweetener — no data is on file for those ingredients. Because this product contains both sodium and potassium, and a number of other active compounds, you should check your exact medications with the tool on this page before starting.

Check your own medications below · Editorial policy · How we use AI

Want to check YOUR meds against PureGreen Protein Vanilla?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker

2,214Drugs

21 Major 1,042 Moderate 1,151 Minor

Ingredients driving the most interactions

Dietary Fiber 2,025

Alfalfa Protein 583

Vitamin A 387

Spirulina powder 327

Sodium 205

Individual Drug Interactions

The ingredients in PureGreen Protein Vanilla interact with 2,214 drugs. Click any drug to see the details.

12 of the 23 ingredients in PureGreen Protein Vanilla interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Alfalfa Protein Vitamin A Spirulina powder Sodium Calcium Iron Potassium Rice Protein Vitamin B12 L-Threonine L-Lysine

All interactions 2,214 Major 21 Moderate 1,042 Minor 1,151

Showing 1–30 of 2,214 drugs.

AcitretinSoriatane

Major

Acitretin belongs to RetinoidsPhotosensitizing DrugsOral Drugs — the drug categories that interact with this product

How Acitretin interacts with PureGreen Protein Vanilla — through 3 ingredients. Tap an ingredient for the detail:

Vitamin ARetinoids Major

Interaction Summary

Concomitant use of retinoids with vitamin A supplements might produce supratherapeutic vitamin A levels.

Read the full Vitamin A + Acitretin interaction

Alfalfa ProteinPhotosensitizing Drugs Moderate

Interaction Summary

Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.

Read the full Alfalfa Protein + Acitretin interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Acitretin interaction

See the Acitretin drug page: uses, dosage & side effects

AlitretinoinPanretin

Major

Alitretinoin belongs to RetinoidsPhotosensitizing DrugsOral Drugs — the drug categories that interact with this product

How Alitretinoin interacts with PureGreen Protein Vanilla — through 3 ingredients. Tap an ingredient for the detail:

Vitamin ARetinoids Major

Interaction Summary

Concomitant use of retinoids with vitamin A supplements might produce supratherapeutic vitamin A levels.

Read the full Vitamin A + Alitretinoin interaction

Alfalfa ProteinPhotosensitizing Drugs Moderate

Interaction Summary

Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.

Read the full Alfalfa Protein + Alitretinoin interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Alitretinoin interaction

See the Alitretinoin drug page: uses, dosage & side effects

BexaroteneTargretin

Major

Bexarotene belongs to RetinoidsOral Drugs — the drug categories that interact with this product

How Bexarotene interacts with PureGreen Protein Vanilla — through 2 ingredients. Tap an ingredient for the detail:

Vitamin ARetinoids Major

Interaction Summary

Concomitant use of retinoids with vitamin A supplements might produce supratherapeutic vitamin A levels.

Read the full Vitamin A + Bexarotene interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Bexarotene interaction

See the Bexarotene drug page: uses, dosage & side effects

CeftriaxoneRocephin

Major

Ceftriaxone belongs to Ceftriaxone (rocephin) — the drug category that interacts with this product

How Ceftriaxone interacts with PureGreen Protein Vanilla — through 1 ingredient. Tap an ingredient for the detail:

CalciumCeftriaxone (rocephin) Major

Interaction Summary

Co-administration of intravenous calcium and ceftriaxone can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys.

Read the full Calcium + Ceftriaxone interaction

See the Ceftriaxone drug page: uses, dosage & side effects

Cobicistat, Elvitegravir, Emtricitabine, Tenofovir Alafenamide FumarateGenvoya

Major

Cobicistat, Elvitegravir, Emtricitabine, Tenofovir Alafenamide Fumarate belongs to Elvitegravir (vitekta)Bictegravir/emtricitabine/tenofovir Alafenamide (biktarvy)Hepatotoxic DrugsOral Drugs — the drug categories that interact with this product

How Cobicistat, Elvitegravir, Emtricitabine, Tenofovir Alafenamide Fumarate interacts with PureGreen Protein Vanilla — through 4 ingredients. Tap an ingredient for the detail:

CalciumElvitegravir (vitekta), Bictegravir/emtricitabine/tenofovir Alafenamide (biktarvy) Major

Interaction Summary

Calcium seems to reduce levels of elvitegravir.

Read the full Calcium + Cobicistat, Elvitegravir, Emtricitabine, Tenofovir Alafenamide Fumarate interaction

IronBictegravir/emtricitabine/tenofovir Alafenamide (biktarvy) Moderate

Interaction Summary

Iron might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.

Read the full Iron + Cobicistat, Elvitegravir, Emtricitabine, Tenofovir Alafenamide Fumarate interaction

Vitamin AHepatotoxic Drugs Moderate

Interaction Summary

Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disease.

Read the full Vitamin A + Cobicistat, Elvitegravir, Emtricitabine, Tenofovir Alafenamide Fumarate interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Cobicistat, Elvitegravir, Emtricitabine, Tenofovir Alafenamide Fumarate interaction

DolutegravirTivicay

Major

Dolutegravir belongs to Dolutegravir (tivicay)Oral Drugs — the drug categories that interact with this product

How Dolutegravir interacts with PureGreen Protein Vanilla — through 3 ingredients. Tap an ingredient for the detail:

CalciumDolutegravir (tivicay) Major

Interaction Summary

Calcium seems to reduce levels of dolutegravir.

Read the full Calcium + Dolutegravir interaction

IronDolutegravir (tivicay) Moderate

Interaction Summary

Iron might decrease dolutegravir levels by reducing its absorption.

Read the full Iron + Dolutegravir interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Dolutegravir interaction

See the Dolutegravir drug page: uses, dosage & side effects

Dolutegravir, Emtricitabine, Tenofovir AlafenamideDolutegravir, Emtricitabine, Tenofovir Alafenamide

Major

Dolutegravir, Emtricitabine, Tenofovir Alafenamide belongs to Dolutegravir (tivicay)Bictegravir/emtricitabine/tenofovir Alafenamide (biktarvy)Hepatotoxic DrugsOral Drugs — the drug categories that interact with this product

How Dolutegravir, Emtricitabine, Tenofovir Alafenamide interacts with PureGreen Protein Vanilla — through 4 ingredients. Tap an ingredient for the detail:

CalciumDolutegravir (tivicay), Bictegravir/emtricitabine/tenofovir Alafenamide (biktarvy) Major

Interaction Summary

Calcium seems to reduce levels of dolutegravir.

Read the full Calcium + Dolutegravir, Emtricitabine, Tenofovir Alafenamide interaction

IronDolutegravir (tivicay), Bictegravir/emtricitabine/tenofovir Alafenamide (biktarvy) Moderate

Interaction Summary

Iron might decrease dolutegravir levels by reducing its absorption.

Read the full Iron + Dolutegravir, Emtricitabine, Tenofovir Alafenamide interaction

Vitamin AHepatotoxic Drugs Moderate

Interaction Summary

Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disease.

Read the full Vitamin A + Dolutegravir, Emtricitabine, Tenofovir Alafenamide interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Dolutegravir, Emtricitabine, Tenofovir Alafenamide interaction

Dolutegravir, RilpivirineJuluca

Major

Dolutegravir, Rilpivirine belongs to Dolutegravir (tivicay)Oral Drugs — the drug categories that interact with this product

How Dolutegravir, Rilpivirine interacts with PureGreen Protein Vanilla — through 3 ingredients. Tap an ingredient for the detail:

CalciumDolutegravir (tivicay) Major

Interaction Summary

Calcium seems to reduce levels of dolutegravir.

Read the full Calcium + Dolutegravir, Rilpivirine interaction

IronDolutegravir (tivicay) Moderate

Interaction Summary

Iron might decrease dolutegravir levels by reducing its absorption.

Read the full Iron + Dolutegravir, Rilpivirine interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Dolutegravir, Rilpivirine interaction

ElvitegravirVitekta

Major

Elvitegravir belongs to Elvitegravir (vitekta)Oral Drugs — the drug categories that interact with this product

How Elvitegravir interacts with PureGreen Protein Vanilla — through 2 ingredients. Tap an ingredient for the detail:

CalciumElvitegravir (vitekta) Major

Interaction Summary

Calcium seems to reduce levels of elvitegravir.

Read the full Calcium + Elvitegravir interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Elvitegravir interaction

Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil FumarateStribild

Major

Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate belongs to Elvitegravir (vitekta)Bictegravir/emtricitabine/tenofovir Alafenamide (biktarvy)Hepatotoxic DrugsOral Drugs — the drug categories that interact with this product

How Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate interacts with PureGreen Protein Vanilla — through 4 ingredients. Tap an ingredient for the detail:

CalciumElvitegravir (vitekta), Bictegravir/emtricitabine/tenofovir Alafenamide (biktarvy) Major

Interaction Summary

Calcium seems to reduce levels of elvitegravir.

Read the full Calcium + Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate interaction

IronBictegravir/emtricitabine/tenofovir Alafenamide (biktarvy) Moderate

Interaction Summary

Iron might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.

Read the full Iron + Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate interaction

Vitamin AHepatotoxic Drugs Moderate

Interaction Summary

Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disease.

Read the full Vitamin A + Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate interaction

Halobetasol Propionate,tazaroteneDuobrii

Major

Halobetasol Propionate,tazarotene belongs to RetinoidsPhotosensitizing Drugs — the drug categories that interact with this product

How Halobetasol Propionate,tazarotene interacts with PureGreen Protein Vanilla — through 2 ingredients. Tap an ingredient for the detail:

Vitamin ARetinoids Major

Interaction Summary

Concomitant use of retinoids with vitamin A supplements might produce supratherapeutic vitamin A levels.

Read the full Vitamin A + Halobetasol Propionate,tazarotene interaction

Alfalfa ProteinPhotosensitizing Drugs Moderate

Interaction Summary

Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.

Read the full Alfalfa Protein + Halobetasol Propionate,tazarotene interaction

IsotretinoinAbsorica, Accutane, Amnesteem, Claravis, Roaccutane, Sotret

Major

Isotretinoin belongs to RetinoidsPhotosensitizing DrugsOral Drugs — the drug categories that interact with this product

How Isotretinoin interacts with PureGreen Protein Vanilla — through 3 ingredients. Tap an ingredient for the detail:

Vitamin ARetinoids Major

Interaction Summary

Concomitant use of retinoids with vitamin A supplements might produce supratherapeutic vitamin A levels.

Read the full Vitamin A + Isotretinoin interaction

Alfalfa ProteinPhotosensitizing Drugs Moderate

Interaction Summary

Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.

Read the full Alfalfa Protein + Isotretinoin interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Isotretinoin interaction

See the Isotretinoin drug page: uses, dosage & side effects

MemantineEbixa

Major

Memantine belongs to Nmda AntagonistsOral Drugs — the drug categories that interact with this product

How Memantine interacts with PureGreen Protein Vanilla — through 2 ingredients. Tap an ingredient for the detail:

L-threonineNmda Antagonists Major

Interaction Summary

Theoretically, threonine might decrease the effects of NMDA antagonists.

Read the full L-threonine + Memantine interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Memantine interaction

See the Memantine drug page: uses, dosage & side effects

Memantine HydrochlorideNamenda

Major

Memantine Hydrochloride belongs to Nmda AntagonistsOral Drugs — the drug categories that interact with this product

How Memantine Hydrochloride interacts with PureGreen Protein Vanilla — through 2 ingredients. Tap an ingredient for the detail:

L-threonineNmda Antagonists Major

Interaction Summary

Theoretically, threonine might decrease the effects of NMDA antagonists.

Read the full L-threonine + Memantine Hydrochloride interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Memantine Hydrochloride interaction

See the Memantine Hydrochloride drug page: uses, dosage & side effects

Memantine, DonepezilNamzaric

Major

Memantine, Donepezil belongs to Nmda AntagonistsOral Drugs — the drug categories that interact with this product

How Memantine, Donepezil interacts with PureGreen Protein Vanilla — through 2 ingredients. Tap an ingredient for the detail:

L-threonineNmda Antagonists Major

Interaction Summary

Theoretically, threonine might decrease the effects of NMDA antagonists.

Read the full L-threonine + Memantine, Donepezil interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Memantine, Donepezil interaction

TazaroteneArazlo, Avage, Fabior, Tazorotene, Zorac

Major

Tazarotene belongs to RetinoidsPhotosensitizing Drugs — the drug categories that interact with this product

How Tazarotene interacts with PureGreen Protein Vanilla — through 2 ingredients. Tap an ingredient for the detail:

Vitamin ARetinoids Major

Interaction Summary

Concomitant use of retinoids with vitamin A supplements might produce supratherapeutic vitamin A levels.

Read the full Vitamin A + Tazarotene interaction

Alfalfa ProteinPhotosensitizing Drugs Moderate

Interaction Summary

Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.

Read the full Alfalfa Protein + Tazarotene interaction

See the Tazarotene drug page: uses, dosage & side effects

TretinoinAltreno, Renova, Retin-A, Vesanoid

Major

Tretinoin belongs to RetinoidsPhotosensitizing DrugsOral Drugs — the drug categories that interact with this product

How Tretinoin interacts with PureGreen Protein Vanilla — through 3 ingredients. Tap an ingredient for the detail:

Vitamin ARetinoids Major

Interaction Summary

Concomitant use of retinoids with vitamin A supplements might produce supratherapeutic vitamin A levels.

Read the full Vitamin A + Tretinoin interaction

Alfalfa ProteinPhotosensitizing Drugs Moderate

Interaction Summary

Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.

Read the full Alfalfa Protein + Tretinoin interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Tretinoin interaction

See the Tretinoin drug page: uses, dosage & side effects

Tretinoin, Benzoyl PeroxideTwyneo

Major

Tretinoin, Benzoyl Peroxide belongs to RetinoidsPhotosensitizing Drugs — the drug categories that interact with this product

How Tretinoin, Benzoyl Peroxide interacts with PureGreen Protein Vanilla — through 2 ingredients. Tap an ingredient for the detail:

Vitamin ARetinoids Major

Interaction Summary

Concomitant use of retinoids with vitamin A supplements might produce supratherapeutic vitamin A levels.

Read the full Vitamin A + Tretinoin, Benzoyl Peroxide interaction

Alfalfa ProteinPhotosensitizing Drugs Moderate

Interaction Summary

Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.

Read the full Alfalfa Protein + Tretinoin, Benzoyl Peroxide interaction

WarfarinWarfarin

Major

Warfarin belongs to Warfarin (coumadin)Anticoagulant/antiplatelet DrugsOral Drugs — the drug categories that interact with this product

How Warfarin interacts with PureGreen Protein Vanilla — through 4 ingredients. Tap an ingredient for the detail:

Alfalfa ProteinWarfarin (coumadin) Major

Interaction Summary

Theoretically, alfalfa might reduce the anticoagulant activity of warfarin.

Read the full Alfalfa Protein + Warfarin interaction

Spirulina PowderAnticoagulant/antiplatelet Drugs Moderate

Interaction Summary

Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.

Read the full Spirulina Powder + Warfarin interaction

Vitamin AWarfarin (coumadin) Moderate

Interaction Summary

Theoretically, high doses of vitamin A could increase the risk of bleeding with warfarin.

Read the full Vitamin A + Warfarin interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Warfarin interaction

See the Warfarin drug page: uses, dosage & side effects

Warfarin SodiumCoumadin, Panwarfin, Sofarin

Major

Warfarin Sodium belongs to Warfarin (coumadin)Anticoagulant/antiplatelet DrugsOral Drugs — the drug categories that interact with this product

How Warfarin Sodium interacts with PureGreen Protein Vanilla — through 4 ingredients. Tap an ingredient for the detail:

Alfalfa ProteinWarfarin (coumadin) Major

Interaction Summary

Theoretically, alfalfa might reduce the anticoagulant activity of warfarin.

Read the full Alfalfa Protein + Warfarin Sodium interaction

Vitamin AWarfarin (coumadin) Moderate

Interaction Summary

Theoretically, high doses of vitamin A could increase the risk of bleeding with warfarin.

Read the full Vitamin A + Warfarin Sodium interaction

Spirulina PowderAnticoagulant/antiplatelet Drugs Moderate

Interaction Summary

Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.

Read the full Spirulina Powder + Warfarin Sodium interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Warfarin Sodium interaction

See the Warfarin Sodium drug page: uses, dosage & side effects

EtretinateTegison

Major

Etretinate belongs to RetinoidsPhotosensitizing DrugsOral Drugs — the drug categories that interact with this product

How Etretinate interacts with PureGreen Protein Vanilla — through 3 ingredients. Tap an ingredient for the detail:

Vitamin ARetinoids Major

Interaction Summary

Concomitant use of retinoids with vitamin A supplements might produce supratherapeutic vitamin A levels.

Read the full Vitamin A + Etretinate interaction

Alfalfa ProteinPhotosensitizing Drugs Moderate

Interaction Summary

Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.

Read the full Alfalfa Protein + Etretinate interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Etretinate interaction

6-mercaptopurinePurinethol

Moderate

6-mercaptopurine belongs to ImmunosuppressantsHepatotoxic DrugsOral Drugs — the drug categories that interact with this product

How 6-mercaptopurine interacts with PureGreen Protein Vanilla — through 4 ingredients. Tap an ingredient for the detail:

Spirulina PowderImmunosuppressants Moderate

Interaction Summary

Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.

Read the full Spirulina Powder + 6-mercaptopurine interaction

Alfalfa ProteinImmunosuppressants Moderate

Interaction Summary

Theoretically, alfalfa might decrease the efficacy of immunosuppressive therapy.

Read the full Alfalfa Protein + 6-mercaptopurine interaction

Vitamin AHepatotoxic Drugs Moderate

Interaction Summary

Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disease.

Read the full Vitamin A + 6-mercaptopurine interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + 6-mercaptopurine interaction

See the 6-mercaptopurine drug page: uses, dosage & side effects

Abacavir Sulfate, Dolutegravir, LamivudineTriumeq

Moderate

Abacavir Sulfate, Dolutegravir, Lamivudine belongs to Hepatotoxic DrugsOral Drugs — the drug categories that interact with this product

How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with PureGreen Protein Vanilla — through 2 ingredients. Tap an ingredient for the detail:

Vitamin AHepatotoxic Drugs Moderate

Interaction Summary

Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disease.

Read the full Vitamin A + Abacavir Sulfate, Dolutegravir, Lamivudine interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Abacavir Sulfate, Dolutegravir, Lamivudine interaction

See the Abacavir Sulfate, Dolutegravir, Lamivudine drug page: uses, dosage & side effects

Abacavir, LamivudineEpzicom

Moderate

Abacavir, Lamivudine belongs to Hepatotoxic DrugsOral Drugs — the drug categories that interact with this product

How Abacavir, Lamivudine interacts with PureGreen Protein Vanilla — through 2 ingredients. Tap an ingredient for the detail:

Vitamin AHepatotoxic Drugs Moderate

Interaction Summary

Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disease.

Read the full Vitamin A + Abacavir, Lamivudine interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Abacavir, Lamivudine interaction

AbciximabReoPro

Moderate

Abciximab belongs to Anticoagulant/antiplatelet DrugsOral Drugs — the drug categories that interact with this product

How Abciximab interacts with PureGreen Protein Vanilla — through 2 ingredients. Tap an ingredient for the detail:

Spirulina PowderAnticoagulant/antiplatelet Drugs Moderate

Interaction Summary

Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.

Read the full Spirulina Powder + Abciximab interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Abciximab interaction

Abiraterone

Moderate

Abiraterone belongs to Hepatotoxic DrugsOral Drugs — the drug categories that interact with this product

How Abiraterone interacts with PureGreen Protein Vanilla — through 2 ingredients. Tap an ingredient for the detail:

Vitamin AHepatotoxic Drugs Moderate

Interaction Summary

Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disease.

Read the full Vitamin A + Abiraterone interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Abiraterone interaction

See the Abiraterone drug page: uses, dosage & side effects

Abiraterone AcetateYonsa, Zytiga

Moderate

Abiraterone Acetate belongs to Hepatotoxic DrugsOral Drugs — the drug categories that interact with this product

How Abiraterone Acetate interacts with PureGreen Protein Vanilla — through 2 ingredients. Tap an ingredient for the detail:

Vitamin AHepatotoxic Drugs Moderate

Interaction Summary

Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disease.

Read the full Vitamin A + Abiraterone Acetate interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Abiraterone Acetate interaction

See the Abiraterone Acetate drug page: uses, dosage & side effects

AbrocitinibCibinqo

Moderate

Abrocitinib belongs to Anticoagulant/antiplatelet DrugsImmunosuppressantsOral Drugs — the drug categories that interact with this product

How Abrocitinib interacts with PureGreen Protein Vanilla — through 3 ingredients. Tap an ingredient for the detail:

Spirulina PowderAnticoagulant/antiplatelet Drugs, Immunosuppressants Moderate

Interaction Summary

Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.

Read the full Spirulina Powder + Abrocitinib interaction

Alfalfa ProteinImmunosuppressants Moderate

Interaction Summary

Theoretically, alfalfa might decrease the efficacy of immunosuppressive therapy.

Read the full Alfalfa Protein + Abrocitinib interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Abrocitinib interaction

See the Abrocitinib drug page: uses, dosage & side effects

AcarboseGlucobay, Prandase, Precose

Moderate

Acarbose belongs to Antidiabetes DrugsHepatotoxic DrugsOral Drugs — the drug categories that interact with this product

How Acarbose interacts with PureGreen Protein Vanilla — through 4 ingredients. Tap an ingredient for the detail:

Spirulina PowderAntidiabetes Drugs Moderate

Interaction Summary

Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.

Read the full Spirulina Powder + Acarbose interaction

Vitamin AHepatotoxic Drugs Moderate

Interaction Summary

Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disease.

Read the full Vitamin A + Acarbose interaction

Alfalfa ProteinAntidiabetes Drugs Moderate

Interaction Summary

Theoretically, alfalfa might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Alfalfa Protein + Acarbose interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Acarbose interaction

See the Acarbose drug page: uses, dosage & side effects

AcebutololRhotral, Sectral

Moderate

Acebutolol belongs to Hepatotoxic DrugsAntihypertensive DrugsOral Drugs — the drug categories that interact with this product

How Acebutolol interacts with PureGreen Protein Vanilla — through 3 ingredients. Tap an ingredient for the detail:

Vitamin AHepatotoxic Drugs Moderate

Interaction Summary

Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disease.

Read the full Vitamin A + Acebutolol interaction

SodiumAntihypertensive Drugs Moderate

Interaction Summary

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.

Read the full Sodium + Acebutolol interaction

Dietary FiberOral Drugs Minor

Interaction Summary

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Read the full Dietary Fiber + Acebutolol interaction

See the Acebutolol drug page: uses, dosage & side effects

Each ingredient & the kinds of drugs it affects

For each ingredient in PureGreen Protein Vanilla with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D

Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D

Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D

Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D

Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B

Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D

Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B

Dietary Fiber full monograph & interactions

Alfalfa Protein6 drug types · 583 drugs

Warfarin (Coumadin)

Theoretically, alfalfa might reduce the anticoagulant activity of warfarin.
Alfalfa contains a large amount of vitamin K. This could theoretically interfere with the activity of warfarin.

Likelihood Probable Evidence D

Antidiabetes Drugs

Theoretically, alfalfa might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that alfalfa decreases blood sugar in diabetic mice. Also, in one case report, a diabetic patient experienced hypoglycemia after consuming alfalfa extract. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D

Contraceptive Drugs

Theoretically, alfalfa might interfere with the activity of contraceptive drugs.
Alfalfa contains coumestrol, a phytoestrogen, and isoflavonoids, which have estrogenic effects.

Likelihood Possible Evidence D

Estrogens

Theoretically, alfalfa might interfere with hormone therapy.
Alfalfa contains coumestrol, a phytoestrogen, and isoflavonoids, which have estrogenic effects.

Likelihood Possible Evidence D

Immunosuppressants

Theoretically, alfalfa might decrease the efficacy of immunosuppressive therapy.
In vitro research and human case reports suggest that alfalfa may have immunostimulant effects.

Likelihood Possible Evidence D

Photosensitizing Drugs

Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.
Animal research suggests that excessive doses of alfalfa may increase photosensitivity, possibly due to its chlorophyll content. It is unclear if this effect would be clinically relevant in humans.

Likelihood Possible Evidence D

Alfalfa Protein full monograph & interactions

Vitamin A4 drug types · 387 drugs

Retinoids

Concomitant use of retinoids with vitamin A supplements might produce supratherapeutic vitamin A levels.
Retinoids, which are vitamin A derivatives, could have additive toxic effects when taken with vitamin A supplements.

Likelihood Probable Evidence D

Hepatotoxic Drugs

Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disease.
The tolerable upper intake level (UL) is the highest level of intake that is likely to pose no risk of adverse effects. Doses of vitamin A above the UL can cause hepatotoxicity, ranging from elevated liver enzymes to liver failure.

Likelihood Possible Evidence C

Tetracycline Antibiotics

Theoretically, taking tetracycline antibiotics with high doses of vitamin A can increase the risk of pseudotumor cerebri.
Benign intracranial hypertension (pseudotumor cerebri) can occur with tetracyclines and with acute or chronic vitamin A toxicity. Case reports suggest that taking tetracyclines and vitamin A concurrently can increase the risk of this condition. Avoid high doses of vitamin A in people taking tetracyclines chronically.

Likelihood Possible Evidence D

Warfarin (Coumadin)

Theoretically, high doses of vitamin A could increase the risk of bleeding with warfarin.
Vitamin A toxicity is associated with hemorrhage and hypoprothrombinemia, possibly due to vitamin K antagonism. Advise patients taking warfarin to avoid doses of vitamin A above the tolerable upper intake level of 10,000 IU/day for adults.

Likelihood Possible Evidence D

Vitamin A full monograph & interactions

Spirulina powder3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs. However, this is unlikely.
Spirulina blue-green algae have shown antiplatelet and anticoagulant effects in vitro. However, one preliminary study in 24 patients receiving spirulina blue-green algae 2.3 grams daily for 2 weeks showed no effect on platelet activation or measures of clotting time.

Likelihood Unlikely Evidence D

Antidiabetes Drugs

Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Human research shows that spirulina blue-green algae can have hypoglycemic effects in patients with diabetes, at least some of whom were using antidiabetes drugs. However, blue-green algae does not seem to improve glycated hemoglobin (HbA1c) levels in patients with diabetes. A meta-analysis of animal studies also suggests that spirulina blue-green algae have hypoglycemic effects.

Likelihood Possible Evidence B

Immunosuppressants

Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Blue-green algae have been shown to stimulate the immune system.

Likelihood Possible Evidence D

Spirulina powder full monograph & interactions

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A

Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D

Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C

Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B

Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D

Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D

Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C

Sodium full monograph & interactions

Calcium18 drug types · 168 drugs

Ceftriaxone (Rocephin)

Co-administration of intravenous calcium and ceftriaxone can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys.
Avoid administering intravenous calcium in any form, such as parenteral nutrition or Lactated Ringers, within 48 hours of intravenous ceftriaxone. Case reports in neonates show that administering intravenous ceftriaxone and calcium can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys. In several cases, neonates have died as a result of this interaction. So far there are no reports in adults; however, there is still concern that this interaction might occur in adults.

Likelihood Probable Evidence D

Dolutegravir (Tivicay)

Calcium seems to reduce levels of dolutegravir.
Advise patients to take dolutegravir either 2 hours before or 6 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium carbonate 1200 mg concomitantly with dolutegravir 50 mg reduces plasma levels of dolutegravir by almost 40%. Calcium appears to decrease levels of dolutegravir through chelation.

Likelihood Probable Evidence B

Elvitegravir (Vitekta)

Calcium seems to reduce levels of elvitegravir.
Advise patients to take elvitegravir either 2 hours before or 2 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium along with elvitegravir can reduce blood levels of elvitegravir through chelation.

Likelihood Probable Evidence B

Aluminum

Calcium citrate might increase aluminum absorption and toxicity. Other types of calcium do not increase aluminum absorption.
Calcium citrate can increase the absorption of aluminum when taken with aluminum hydroxide. The increase in aluminum levels may become toxic, particularly in individuals with kidney disease. However, the effect of calcium citrate on aluminum absorption is due to the citrate anion rather than calcium cation. Calcium acetate does not appear to increase aluminum absorption.

Likelihood Possible Evidence B

Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Calcium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide and calcium can be taken together if taken with food. However, if taken on an empty stomach, bictegravir/emtricitabine/tenofovir alafenamide should not be taken with, or 2 hours after, calcium containing products.

Likelihood Probable Evidence D

Bisphosphonates

Calcium reduces the absorption of bisphosphonates.
Advise patients to take bisphosphonates at least 30 minutes before calcium, but preferably at a different time of day. Calcium supplements decrease absorption of bisphosphonates.

Likelihood Probable Evidence C

Calcipotriene (Dovonex)

Taking calcipotriene with calcium might increase the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with calcium supplements might increase the risk of hypercalcemia.

Likelihood Possible Evidence B

Digoxin (Lanoxin)

Using intravenous calcium with digoxin might increase the risk of fatal cardiac arrhythmias.
Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. However, one retrospective analysis of clinical data suggests that intravenous calcium does not increase the risk of dysrhythmias or mortality in patients receiving digoxin.

Likelihood Possible Evidence B

Diltiazem (Cardizem, Others)

Theoretically, calcium may reduce the therapeutic effects of diltiazem.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, calcium might increase this risk of hypercalcemia and reduce the effectiveness of diltiazem.

Likelihood Probable Evidence D

Levothyroxine (Synthroid, Others)

Calcium seems to reduce the absorption and effectiveness of levothyroxine.
Advise patients to take levothyroxine and calcium supplements at least 4 hours apart. Calcium reduces levothyroxine absorption, probably by forming insoluble complexes. Calcium carbonate supplements reduce effectiveness of levothyroxine in patients with hypothyroidism.

Likelihood Probable Evidence B

Lithium

Theoretically, concomitant use of calcium and lithium may increase this risk of hypercalcemia.
Clinical research suggests that long-term use of lithium may cause hypercalcemia in 10% to 60% of patients. Theoretically, concomitant use of lithium and calcium supplements may further increase this risk.

Likelihood Possible Evidence B

Quinolone Antibiotics

Calcium seems to reduce the absorption of quinolone antibiotics.
Advise patients to take oral quinolones at least 2 hours before or 4-6 hours after calcium supplements or calcium-fortified foods. Taking calcium at the same time as oral quinolones can reduce quinolone absorption. Calcium binds to quinolones in the gut.

Likelihood Probable Evidence B

Raltegravir (Isentress)

Calcium may reduce levels of raltegravir.
Pharmacokinetic research shows that taking a single dose of calcium carbonate 3000 mg along with raltegravir 400 mg twice daily modestly decreases the mean area under the curve of raltegravir, but the decrease does not necessitate a dose adjustment of raltegravir. However, a case of elevated HIV-1 RNA levels and documented resistance to raltegravir has been reported for a patient taking calcium carbonate 1 gram three times daily plus vitamin D3 (cholecalciferol) 400 IU three times daily in combination with raltegravir 400 mg twice daily for 11 months. It is thought that calcium reduced raltegravir levels by chelation, leading to treatment failure.

Likelihood Possible Evidence B

Sotalol (Betapace)

Calcium seems to reduce the absorption of sotalol.
Advise patients to separate doses by at least 2 hours before or 4-6 hours after calcium. Calcium appears to reduce the absorption of sotalol, probably by forming insoluble complexes.

Likelihood Possible Evidence B

Tetracycline Antibiotics

Calcium seems to reduce the absorption of tetracycline antibiotics.
Advise patients to take oral tetracyclines at least 2 hours before, or 4-6 hours after calcium supplements. Taking calcium at the same time as oral tetracyclines can reduce tetracycline absorption. Calcium binds to tetracyclines in the gut.

Likelihood Probable Evidence C

Thiazide Diuretics

Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Thiazides reduce calcium excretion by the kidneys. Using thiazides along with moderately large amounts of calcium carbonate increases the risk of milk-alkali syndrome (hypercalcemia, metabolic alkalosis, renal failure). Patients may need to have their serum calcium levels and/or parathyroid function monitored regularly.

Likelihood Probable Evidence C

Verapamil (Calan, Others)

Theoretically, calcium may reduce the therapeutic effects of verapamil.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, use of calcium supplements may increase this risk of hypercalcemia and reduce the effectiveness of verapamil.

Likelihood Probable Evidence D

Calcium Channel Blockers

Intravenous calcium may decrease the effects of calcium channel blockers; oral calcium is unlikely to have this effect.
Intravenous calcium is used to decrease the effects of calcium channel blockers in the management of overdose. Intravenous calcium gluconate has been used before intravenous verapamil (Isoptin) to prevent or reduce the hypotensive effects without affecting the antiarrhythmic effects. But there is no evidence that dietary or supplemental calcium when taken orally interacts with calcium channel blockers.

Likelihood Unlikely Evidence D

Calcium full monograph & interactions

Iron13 drug types · 80 drugs

Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Iron might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide and iron can be taken together if taken with food. However, if taken on an empty stomach, bictegravir/emtricitabine/tenofovir alafenamide should not be taken with, or 2 hours after, iron containing products.

Likelihood Probable Evidence D

Bisphosphonates

Iron reduces the absorption of bisphosphonates.
Advise patients that doses of bisphosphonates should be separated by at least two hours from doses of all other medications, including supplements such as iron. Divalent cations, including iron, can decrease absorption of bisphosphonates by forming insoluble complexes in the gastrointestinal tract.

Likelihood Probable Evidence D

Denosumab (Prolia, Others)

Administration of intravenous iron within one month of denosumab administration might increase the risk of severe hypophosphatemia and hypocalcemia.
A case of severe hypocalcemia (albumin corrected calcium 6.88 mg/dL, ionized calcium 3.68 mg/dL) and hypophosphatemia (<0.5 mg/dL) with respiratory acidosis, QT interval prolongation, and nonsustained ventricular tachycardia was reported in a 76-year-old male who had received an iron polymaltose infusion within 2 weeks of a subcutaneous injection of denosumab. Serum parathyroid hormone was also elevated (348 pg/mL). Subsequent iron infusions with iron polymaltose and ferric carboxymaltose were followed by transient hypophosphatemia, but without hypocalcemia. Additionally, a literature review describes 6 additional cases of hypophosphatemia and hypocalcemia in patients 52-92 years of age who had been administered intravenous iron as either ferric carboxymaltose or iron polymaltose and subcutaneous denosumab within 1-4 weeks of each other.

Likelihood Possible Evidence D

Dolutegravir (Tivicay)

Iron might decrease dolutegravir levels by reducing its absorption.
Advise patients to take dolutegravir at least 2 hours before or 6 hours after taking iron. Pharmacokinetic research shows that iron can decrease the absorption of dolutegravir from the gastrointestinal tract through chelation. When taken under fasting conditions, a single dose of ferrous fumarate 324 mg orally along with dolutegravir 50 mg reduces overall exposure to dolutegravir by 54%.

Likelihood Probable Evidence B

Integrase Inhibitors

Theoretically, taking iron along with integrase inhibitors might decrease the levels and clinical effects of these drugs.
Iron is a divalent cation. There is concern that iron may decrease the absorption of integrase inhibitors from the gastrointestinal tract through chelation. One pharmacokinetic study shows that iron can decrease blood levels of the specific integrase inhibitor dolutegravir through chelation. Also, other pharmacokinetic research shows that other divalent cations such as calcium can decrease the absorption and levels of some integrase inhibitors through chelation.

Likelihood Possible Evidence D

Levodopa

Iron might decrease levodopa levels by reducing its absorption.
Advise patients to separate doses of levodopa and iron as much as possible. There is some evidence in healthy people that iron forms chelates with levodopa, reducing the amount of levodopa absorbed by around 50%. The clinical significance of this hasn't been determined.

Likelihood Probable Evidence B

Levothyroxine (Synthroid, Others)

Iron might decrease levothyroxine levels by reducing its absorption.
Advise patients to separate levothyroxine and iron doses by at least 2 hours. Iron can decrease the absorption and efficacy of levothyroxine by forming insoluble complexes in the gastrointestinal tract.

Likelihood Probable Evidence B

Methyldopa (Aldomet)

Iron might decrease methyldopa levels by reducing its absorption.
Advise patients to separate methyldopa and iron doses by at least 2 hours. Iron can decrease the absorption of methyldopa from the gastrointestinal tract through chelation, resulting in increases in blood pressure.

Likelihood Probable Evidence B

Mycophenolate Mofetil (Cellcept)

Theoretically, iron might decrease mycophenolate mofetil levels by reducing its absorption.
Advise patients to take iron 4-6 hours before, or 2 hours after, mycophenolate mofetil. It has been suggested that a decrease of absorption is possible, probably by forming nonabsorbable chelates. However, mycophenolate pharmacokinetics are not affected by iron supplementation in available clinical research.

Likelihood Unlikely Evidence D

Penicillamine (Cuprimine, Depen)

Iron might decrease penicillamine levels by reducing its absorption.
Advise patients to separate penicillamine and iron doses by at least 2 hours. Oral iron supplements can reduce absorption of penicillamine by 30% to 70%, probably due to chelate formation. In people with Wilson's disease, this interaction has led to reduced efficacy of penicillamine.

Likelihood Probable Evidence D

Quinolone Antibiotics

Iron might decrease levels of quinolone antibiotics by reducing their absorption.
Advise patients to separate quinolone antibiotics and iron doses by at least 2 hours. Iron decreases the absorption of quinolones due to formation of insoluble complexes in the gastrointestinal tract.

Likelihood Probable Evidence D

Tetracycline Antibiotics

Iron might decrease levels of tetracycline antibiotics by reducing their absorption.
Advise patients to take iron at least 2 hours before or 4 hours after tetracycline antibiotics. Concomitant use can decrease absorption of tetracycline antibiotics from the gastrointestinal tract by 50% to 90%.

Likelihood Probable Evidence D

Chloramphenicol

Theoretically, taking chloramphenicol with iron might reduce the response to iron therapy in iron deficiency anemia.
Chloramphenicol interferes with erythrocyte maturation. However, since chloramphenicol isn't usually taken for prolonged periods, this isn't likely to be clinically significant.

Likelihood Unlikely Evidence D

Iron full monograph & interactions

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C

Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C

Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C

Potassium full monograph & interactions

Rice Protein1 drug type · 23 drugs

Ace Inhibitors (Aceis)

In laboratory research, hydrolyzed rice protein inhibits angiotensin-converting enzyme (ACE). In animal research, the inhibition of ACE is correlated with a reduction in systolic blood pressure. So far, this effect has not been shown in humans. Theoretically, concomitant use of rice protein and ACE inhibitors may increase the risk of blood pressure becoming too low. Use with caution. ACE inhibitors include benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), and trandolapril (Mavik).

Likelihood Possible Evidence D

Rice Protein full monograph & interactions

Vitamin B121 drug type · 20 drugs

Metformin (Glucophage)

Metformin, a common medication used to manage type 2 diabetes, has been associated with lower vitamin B12 levels in some individuals. Prolonged use of metformin can interfere with the absorption of B12 in the digestive system, potentially leading to a deficiency in this essential vitamin.

Likelihood Possible Evidence A

Vitamin B12 full monograph & interactions

L-Threonine1 drug type · 3 drugs

Nmda Antagonists

Theoretically, threonine might decrease the effects of NMDA antagonists.
Threonine increases central nervous system (CNS) glycine levels. Glycine seems to bind a site on NMDA receptors and enhance the activity of the receptors.

Likelihood Likely Evidence B

L-Threonine full monograph & interactions

L-Lysine1 drug type · 1 drug

5-Ht4 Agonists

Theoretically, lysine may reduce the effects of 5-HT4 agonists.
Animal research suggests that L-lysine is a partial serotonin receptor 4 (5-HT4) antagonist and inhibits diarrhea induced by the 5-HT4 agonist, 5-hydroxytryptophane.

Likelihood Unlikely Evidence D

L-Lysine full monograph & interactions

The maker

Brand information

Manufacturer and brand details for PureGreen Protein Vanilla, from the product label.

Vibrant Health

See all Vibrant Health products

Name: Vibrant Health
City: Canaan
State: CT
ZipCode: 06018
Phone Number: 1-800-242-1835
Web Address: www.vibranthealth.us

Pharmacist Counseling Corner

PureGreen Protein Vanilla by Vibrant Health: Common Questions

Does PureGreen Protein Vanilla by Vibrant Health interact with any medications?

Yes. Based on its ingredients, PureGreen Protein Vanilla has a known interaction with 2,214 medications, including 21 rated major. Use the checker to see how it interacts with a specific drug.

How can one product interact with so many drugs?

PureGreen Protein Vanilla contains 23 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.

Where does this information come from?

The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.

Does this product contain any fillers or additives?

The product facts show no inactive other ingredients listed, so no fillers or binders are noted in the data we hold. The 20 active ingredients include the protein sources, amino acids, vitamins, minerals, enzymes, and natural flavoring.

Is this safe to use if I'm pregnant?

Calcium and potassium from food are considered safe in pregnancy. However, vitamin A at high doses is possibly unsafe in pregnancy because it can cause birth defects. Since this product contains added vitamin A, you should talk with your doctor or midwife before using it — they can tell you whether the amount is appropriate for your situation.

Can I use this if I'm taking blood pressure medication?

The sodium in this product can potentially reduce how well blood pressure medications work, and potassium can raise levels of certain blood pressure drugs to dangerous heights. You need to discuss this specific product with your doctor or pharmacist before starting it — they know your exact medication and can advise whether it's safe for you.

Will this help me build muscle?

The product contains multiple protein sources (pea, alfalfa, and rice) designed to support protein intake, which is needed for muscle maintenance and growth. However, the evidence we hold on these specific ingredients for muscle strength and exercise recovery is Insufficient to Rate their effectiveness — the benefit depends on your overall diet, training, and individual factors.

What should I watch for if I start this product?

Most people tolerate the ingredients at recommended doses. Watch for digestive upset (nausea, diarrhea, bloating, constipation), headache, or skin reactions. If you experience unusual symptoms or if you take medications, stop and contact your pharmacist or doctor to make sure it is not interacting with your drugs.

Is there vitamin A in this product, and is it safe?

Yes, this product contains vitamin A, which is Effective for vitamin A deficiency and Possibly Effective for aging skin. At normal recommended amounts, it is safe. However, vitamin A builds up in your body, so high doses can be toxic and cause serious liver damage. High-dose vitamin A is possibly unsafe in pregnancy. Check the label for the amount and discuss it with your doctor, especially if you are pregnant or take other supplements containing vitamin A.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Go deeper

The Full Monographs Behind PureGreen Protein Vanilla’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Black Psyllium

Interacts with 2,025 drugs

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...

Read the full Black Psyllium monograph → Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph → Herb & supplement monograph

Calcium

Interacts with 168 drugs

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet falls short. Most people do best getting...

Read the full Calcium monograph → Herb & supplement monograph

Iron

Interacts with 80 drugs

Iron is an essential mineral your body needs to make hemoglobin and carry oxygen in the blood. Supplements are mainly useful for treating or preventing iron deficiency and iron-deficiency an...

Read the full Iron monograph → Herb & supplement monograph

Vitamin A

Interacts with 387 drugs

Vitamin A is an essential nutrient important for vision, skin, immune function, and growth. Most people get enough from a balanced diet, and supplements are mainly useful for correcting a tr...

Read the full Vitamin A monograph → Herb & supplement monograph

Vanilla

Vanilla is best known and very safe as a food flavoring, and small amounts used in cooking are not a concern for most people. As a health supplement, evidence for any specific medical benefi...

Read the full Vanilla monograph → Herb & supplement monograph

Methionine

Methionine is an essential amino acid that your body needs for protein building and many basic chemical reactions. Most people get enough from a normal diet, and supplements are generally no...

Read the full Methionine monograph → Herb & supplement monograph

Threonine

Interacts with 3 drugs

Threonine is an essential amino acid your body needs but cannot make, so you must get it from food or supplements. Most people get plenty from a normal diet, and high-quality evidence for ta...

Read the full Threonine monograph → Herb & supplement monograph

Lysine

Interacts with 1 drug

Lysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to try to prevent or shorten cold sores, but...

Read the full Lysine monograph → Herb & supplement monograph

Vitamin B12

Interacts with 20 drugs

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very helpful for people who are deficient — su...

Read the full Vitamin B12 monograph → Herb & supplement monograph

Proteolytic Enzymes (proteases)

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...

Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monograph

Pea Protein

Pea protein is a plant-based protein powder made from yellow split peas, commonly used by people who want a dairy-free or vegan source of protein to support muscle and overall protein intake...

Read the full Pea Protein monograph → Herb & supplement monograph

Blue-green Algae

Interacts with 327 drugs

Blue-green algae are nutrient-rich aquatic microorganisms (such as spirulina and Klamath Lake algae) taken as a supplement for energy, nutrition, and general wellness. Evidence for most heal...

Read the full Blue-green Algae monograph → Herb & supplement monograph

Alfalfa

Interacts with 583 drugs

Alfalfa is a nutrient-rich legume that people use for high cholesterol, menopause symptoms, and general wellness, but solid human evidence for most of these uses is limited. It is best avoid...

Read the full Alfalfa monograph → Herb & supplement monograph

Rice Protein

Interacts with 23 drugs

Rice protein is a plant-based protein powder made from rice that offers an easy way to add protein to your diet, especially if you avoid dairy or animal products. It is generally considered...

Read the full Rice Protein monograph →

Sources

Sources & How We Checked

PureGreen Protein Vanilla's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 355 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Psyllium 18 references

McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
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Sodium 38 references

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Potassium 12 references

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Calcium 62 references

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Iron 72 references

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Vanilla 5 references

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Methionine 12 references

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Threonine 4 references

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Lysine 7 references

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Vitamin B12 30 references

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Proteolytic Enzymes (proteases) 3 references

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Pea Protein 1 reference

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Blue-green Algae 22 references

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Hsiao G, Chou PH, Shen MY, et al. C-phycocyanin, a very potent and novel platelet aggregation inhibitor from Spirulina platensis. J Agric Food Chem 2005;53:7734-40.
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Madhyastha, H. K., Radha, K. S., Sugiki, M., Omura, S., and Maruyama, M. Purification of c-phycocyanin from Spirulina fusiformis and its effect on the induction of urokinase-type plasminogen activator from calf pulmonary endothelial cells. Phytomedicine PubMed
Mazokopakis, E. E., Karefilakis, C. M., Tsartsalis, A. N., Milkas, A. N., and Ganotakis, E. S. Acute rhabdomyolysis caused by Spirulina (Arthrospira platensis). Phytomedicine. 2008;15(6-7):525-527. PubMed
Halidou, Doudou M., Degbey, H., Daouda, H., Leveque, A., Donnen, P., Hennart, P., and Dramaix-Wilmet, M. [The effect of spiruline during nutritional rehabilitation: systematic review]. Rev.Epidemiol.Sante Publique 2008;56(6):425-431.
Konno, T., Umeda, Y., Umeda, M., Kawachi, I., Oyake, M., and Fujita, N. [A case of inflammatory myopathy with widely skin rash following use of supplements containing Spirulina]. Rinsho Shinkeigaku 2011;51(5):330-333. PubMed
Le TM, Knulst AC, Röckmann H. Anaphylaxis to Spirulina confirmed by skin prick test with ingredients of Spirulina tablets. Food Chem Toxicol 2014;74:309-10. PubMed
Rzymski P, Niedzielski P, Kaczmarek N, Jurczak T, Klimaszyk P. The multidisciplinary approach to safety and toxicity assessment of microalgae-based food supplements following clinical cases of poisoning. Harmful Algae 2015;46:34-42. DOI
Petrus M, Culerrier R, Campistron M, et al. First case report of anaphylaxis to spirulin: identification of phycocyanin as responsible allergen. Allergy 2010;65(7):924-5. PubMed
Marles RJ, Barrett ML, Barnes J, et al. United States Pharmacopeia safety evaluation of spirulina. Crit Rev Food Sci Nutr 2011;51(7):593-604. PubMed
Majdoub H, Ben Mansour M, Chaubet F, et al. Anticoagulant activity of a sulfated polysaccharide from the green alga Arthrospira platensis. Biochim Biophys Acta 2009;1790(10):1377-81. PubMed
Cha BG, Kwak HW, Park AR, et al. Structural characteristics and biological performance of silk fibroin nanofiber containing microalgae spirulina extract. Biopolymers 2014;101(4):307-18. PubMed
Jensen GS, Drapeau C, Lenninger M, Benson KF. Clinical safety of a high dose of phycocyanin-enriched aqueous extract from Arthrospira (Spirulina) platensis: results from a randomized, double-Blind, placebo-controlled study with a focus on anticoagulant ac
Hamedifard Z, Milajerdi A, Reiner Z, Taghizadeh M, Kolahdooz F, Asemi Z. The effects of spirulina on glycemic control and serum lipoproteins in patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized con
Moradi S, Zobeiri M, Feizi A, Clark CCT, Entezari MH. The effects of spirulina (Arthrospira platensis) supplementation on anthropometric indices, blood pressure, sleep quality, mental health, fatigue status and quality of life in patients with ulcerative
Ghanbari F, Amerizadeh A, Behshood P, Moradi S, Asgary S. Effect of microalgae arthrospira on biomarkers of glycemic control and glucose metabolism: a systematic Review and meta-analysis. Curr Probl Cardiol 2022;47(10):100942. PubMed

See these in context on the Blue-green Algae monograph →

Alfalfa 32 references

Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
Kurzer MS, Xu X. Dietary phytoestrogens. Annu Rev Nutr 1997;17:353-81. PubMed
Farber JM, Carter AO, Varughese PV, et al. Listeriosis traced to the consumption of alfalfa tablets and soft cheese [Letter to the Editor]. N Engl J Med 1990;322:338. PubMed
Molgaard J, von Schenck H, Olsson AG. Alfalfa seeds lower low density lipoprotein cholesterol and apolipoprotein B concentrations in patients with type II hyperlipoproteinemia. Atherosclerosis 1987;65:173-9. PubMed
Light TD, Light JA. Acute renal transplant rejection possibly related to herbal medications. Am J Transplant 2003;3:1608-9. PubMed
Prete PE. The mechanism of action of L-canavanine in inducing autoimmune phenomena. Arthritis Rheum 1985;28:1198-200. PubMed
Alcocer-Varela J, Iglesias A, Llorente L, Alarcon-Segovia D. Effects of L-canavanine on T cells may explain the induction of systemic lupus erythematosus by alfalfa. Arthritis Rheum 1985;28:52-7. PubMed
Roberts JL, Hayashi JA. Exacerbation of SLE associated with alfalfa ingestion. N Engl J Med 1983;308:1361. DOI
Feingold, R. M. Should we fear "health foods"? Arch Intern Med 7-12-1999;159(13):1502. PubMed
Taormina, P. J., Beuchat, L. R., and Slutsker, L. Infections associated with eating seed sprouts: an international concern. Emerg.Infect.Dis 1999;5(5):626-634. PubMed
Backer, H. D., Mohle-Boetani, J. C., Werner, S. B., Abbott, S. L., Farrar, J., and Vugia, D. J. High incidence of extra-intestinal infections in a Salmonella Havana outbreak associated with alfalfa sprouts. Public Health Rep. 2000;115(4):339-345. PubMed
Mohle-Boetani J, Werner B, Polumbo M, and et al. From the Centers for Disease Control and Prevention. Alfalfa sprouts-- Arizona, California, Colorado, and New Mexico, February-April, 2001. JAMA 2-6-2002;287(5):581-582.
Howard, M. B. and Hutcheson, S. W. Growth dynamics of Salmonella enterica strains on alfalfa sprouts and in waste seed irrigation water. Appl.Environ.Microbiol. 2003;69(1):548-553.
Winthrop, K. L., Palumbo, M. S., Farrar, J. A., Mohle-Boetani, J. C., Abbott, S., Beatty, M. E., Inami, G., and Werner, S. B. Alfalfa sprouts and Salmonella Kottbus infection: a multistate outbreak following inadequate seed disinfection with heat and chl
Strapp, C. M., Shearer, A. E., and Joerger, R. D. Survey of retail alfalfa sprouts and mushrooms for the presence of Escherichia coil O157:H7, Salmonella, and Listeria with BAX, and evaluation of this polymerase chain reaction-based system with experimen
Akaogi, J., Barker, T., Kuroda, Y., Nacionales, D. C., Yamasaki, Y., Stevens, B. R., Reeves, W. H., and Satoh, M. Role of non-protein amino acid L-canavanine in autoimmunity. Autoimmun.Rev 2006;5(6):429-435. PubMed
Burden and causes of foodborne disease in Australia: Annual report of the OzFoodNet network, 2005. Commun.Dis Intell. 2006;30(3):278-300.
Shemesh, M., Lindner, H. R., and Ayalon, N. Affinity of rabbit uterine oestradiol receptor for phyto-oestrogens and its use in a competitive protein-binding radioassay for plasma coumestrol. J Reprod.Fertil. 1972;29(1):1-9. PubMed
Elakovich, S. D. and Hampton, J. M. Analysis of coumestrol, a phytoestrogen, in alfalfa tablets sold for human consumption. J Agric.Food Chem. 1984;32(1):173-175. PubMed
Malinow, M. R., Bardana, E. J., Jr., Pirofsky, B., Craig, S., and McLaughlin, P. Systemic lupus erythematosus-like syndrome in monkeys fed alfalfa sprouts: role of a nonprotein amino acid. Science 4-23-1982;216(4544):415-417. PubMed
Malinow, M. R., McLaughlin, P., and Stafford, C. Alfalfa seeds: effects on cholesterol metabolism. Experientia 5-15-1980;36(5):562-564. PubMed
Farnsworth, N. R. Alfalfa pills and autoimmune diseases. Am J Clin Nutr. 1995;62(5):1026-1028. DOI
Herbert, V. and Kasdan, T. S. Alfalfa, vitamin E, and autoimmune disorders. Am J Clin Nutr 1994;60(4):639-640.
Mahon, B. E., Ponka, A., Hall, W. N., Komatsu, K., Dietrich, S. E., Siitonen, A., Cage, G., Hayes, P. S., Lambert-Fair, M. A., Bean, N. H., Griffin, P. M., and Slutsker, L. An international outbreak of Salmonella infections caused by alfalfa sprouts grow
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Kaufman W. Alfalfa seed dermatitis. JAMA 1954;155(12):1058-1059. PubMed
Ponka A, Andersson Y, Siitonen A, and et al. Salmonella in alfalfa sprouts. Lancet 1995;345:462-463. PubMed
Puschner B, Chen X, Read D, Affolter VK. Alfalfa hay induced primary photosensitization in horses. Vet J. 2016 May;211:32-8. PubMed

See these in context on the Alfalfa monograph →

Rice Protein 6 references

Joy JM, Lowery RP, Wilson JM, et al. The effects of 8 weeks of whey or rice protein supplementation on body composition and exercise performance. Nutr J 2013;12:86. PubMed
Li GH, Qu MR, Wan JZ, You JM. Antihypertensive effect of rice protein hydrolysate with in vitro angiotensin I-converting enzyme inhibitory activity in spontaneously hypertensive rats. Asia Pac J Clin Nutr. 2007;16 Suppl 1:275-80.
Reche M, Pascual C, Fiandor A, et al. The effect of a partially hydrolysed formula based on rice protein in the treatment of infants with cow's milk protein allergy. Pediatr Allergy Immunol. 2010;21(4 Pt 1):577-85. PubMed
Amended final report on the safety assessment of Oryza sativa (rice) bran oil, Oryza sativa (rice) germ oil, rice bran acid, Oryza sativa (rice) bran wax, hydrogenated rice bran wax, Oryza sativa (rice) bran extract, Oryza sativa (rice) extract, Oryza sat
Yasutomi M, Kosaka T, Kawakita A, et al. Rice protein-induced enterocolitis syndrome with transient specific IgE to boiled rice but not to retort-processed rice. Pediatr Int. 2014;56(1):110-2.
Hojsak I, Kljaic-Turkalj M, Misak Z, Kolacek S. Rice protein-induced enterocolitis syndrome. Clin Nutr. 2006;25(3):533-6. PubMed

See these in context on the Rice Protein monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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PureGreen Protein Vanilla Ingredients & Drug Interactions

Check Your Meds Against PureGreen Protein Vanilla by Vibrant Health

HelloPharmacist Scorecard of PureGreen Protein Vanilla by Vibrant Health

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PureGreen Protein Vanilla by Vibrant Health label

The Ingredients in PureGreen Protein Vanilla by Vibrant Health

Sugar

Protein

L-Valine

Alpha-Galactosidase

Natural Almond flavor

Natural Sweetener

PureGreen Protein Vanilla by Vibrant Health Drug Interactions

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Ingredients driving the most interactions

Individual Drug Interactions

Each ingredient & the kinds of drugs it affects

Dietary Fiber7 drug types · 2,025 drugs

Alfalfa Protein6 drug types · 583 drugs

Vitamin A4 drug types · 387 drugs

Spirulina powder3 drug types · 327 drugs

Sodium7 drug types · 205 drugs

Calcium18 drug types · 168 drugs

Iron13 drug types · 80 drugs

Potassium3 drug types · 62 drugs

Rice Protein1 drug type · 23 drugs

Vitamin B121 drug type · 20 drugs

L-Threonine1 drug type · 3 drugs

L-Lysine1 drug type · 1 drug

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The Full Monographs Behind PureGreen Protein Vanilla’s Ingredients

Black Psyllium

Sodium

Potassium

Calcium

Iron

Vitamin A

Vanilla

Methionine

Threonine

Lysine

Vitamin B12

Proteolytic Enzymes (proteases)

Pea Protein

Blue-green Algae

Alfalfa

Rice Protein

Sources & How We Checked

The 355 references behind this product’s interaction data