Saw Palmetto Complex Ingredients & Drug Interactions
by Swanson
What is this page for?
First and foremost: checking Saw Palmetto Complex against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Saw Palmetto Complex is a dietary supplement by Swanson with 4 active ingredients. Its ingredients are commonly taken for heart health, prostate health, antioxidant support.Based on those ingredients, 175 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Supercritical CO2 Saw Palmetto berry extract, Lycopene, Pumpkin seed Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Saw Palmetto Complex by Swanson
Ask about any prescription or over-the-counter medication and we check it for interactions with Saw Palmetto Complex by Swanson — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Saw Palmetto Complex by Swanson
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This complex brings together four active ingredients focused on prostate and urinary health. You get lycopene, a carotenoid from tomatoes; pumpkin seed oil, which concentrates the seed's nutrients; supercritical CO2 saw palmetto berry extract, a concentrated form of the saw palmetto plant; and pygeum extract from the pygeum tree bark.
The inactive ingredients — gelatin, glycerin, soybean oil, beeswax, water, carob, soy lecithin, and titanium dioxide — are the capsule and supporting materials.
Does it work?
Strong evidence
The evidence for what this product can do is mixed. Saw palmetto extract shows insufficient reliable evidence for benign prostatic hyperplasia (BPH), the most common reason people take it, though it's possibly effective for transurethral resection of the prostate (TURP), a specific procedure.
Pumpkin seed oil is possibly effective for BPH. Pygeum extract is likely effective for BPH, making it the strongest player here for that condition.
Lycopene is possibly effective for prostate cancer but possibly ineffective for bladder cancer and diabetes — and the evidence is insufficient for its other uses. The bottom line: pygeum has the most solid evidence, but for most of these conditions, the data either isn't strong enough or suggests limited benefit.
How safe is it?
Well-documented data
Saw palmetto is generally well tolerated, though mild side effects like abdominal pain, diarrhea, nausea, headache, and dizziness can occur. Rare cases of heart rhythm problems have been reported.
Lycopene supplements can cause gastrointestinal side effects including diarrhea, nausea, vomiting, and bloating. Pumpkin seed oil is generally well tolerated but may cause abdominal discomfort, diarrhea, nausea, or vomiting; anaphylaxis is rare.
Pygeum is generally well tolerated short-term, though nausea and abdominal pain have appeared in some trials at rates similar to placebo. Pregnancy: saw palmetto is likely unsafe and should be avoided — the safety data advises against it.
For lycopene and pumpkin seed oil supplements during pregnancy, there isn't enough data to know either way; talk with your doctor or pharmacist for personalized advice. Pygeum has no established safe use in pregnancy.
Breastfeeding: the safety data advises against saw palmetto. For lycopene, pumpkin seed oil, and pygeum, the evidence is insufficient — again, ask your doctor or pharmacist.
Meds to double-check
Moderate interaction found
Before you take this product, check if you're on blood thinners or antiplatelet drugs (like warfarin or aspirin) — both lycopene and saw palmetto may increase bleeding risk. Birth control pills and estrogen therapy may be less effective with saw palmetto.
If you take lithium, pumpkin seed oil might raise your levels. No interactions are documented for pygeum in our data.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This is a multi-ingredient prostate formula where pygeum has the strongest evidence for benign prostatic hyperplasia. If you take blood thinners, birth control, estrogen, or lithium, you need to check your exact medications first — the interactions are real.
Pregnancy and breastfeeding are off the table, especially for saw palmetto. Talk to your pharmacist before you start, especially if you're on any regular medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Saw Palmetto Complex, straight from the product label.
| Brand | Swanson |
|---|---|
| Barcode (UPC) | 087614020136 |
| Net contents | 60 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Jun 24, 2019 |
| DSLD ID | 204119 |
| Product type | Other Combinations |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult Male (18-50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Saw Palmetto Complex by Swanson, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Lycopene | 5 mg | -- |
| Pumpkin seed Oil | 40 mg | -- |
| Supercritical CO2 Saw Palmetto berry extract | 160 mg | -- |
| Pygeum extract | 50 mg | -- |
Other ingredients: Gelatin, Glycerin, Soybean Oil, yellow Beeswax, purified Water, Carob, Soy Lecithin, Titanium Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, take one softgel two times per day with food and water.
Precautions
Warning: For adults only.
Consult your physician before using this or any product if you are pregnant or nursing, taking medication or have a medical condition.
Keep out of reach of children.
Do not use if seal is broken.
Contains soy.
Storage
Store in a cool, dry place. Do not refrigerate.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formula
Prostate Health
Contains soy.
General Statements
Comprehensive formula
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Saw Palmetto Complex by Swanson label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Saw Palmetto Complex by Swanson
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Lycopene
Interacts with122 drugs
Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible hear...
Lycopene monograph & interactionsPumpkin seed Oil
Interacts with1 drug
Pumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The...
Pumpkin seed Oil monograph & interactionsSupercritical CO2 Saw Palmetto berry extract
Interacts with174 drugs
Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no bett...
Supercritical CO2 Saw Palmetto berry extract monograph & interactionsPygeum extract
No knowninteractions
Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some st...
Pygeum extract monograph & interactionsOther (inactive) ingredients: Gelatin, Glycerin, Soybean Oil, Yellow Beeswax, Purified Water, Carob, Soy Lecithin, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.
Saw Palmetto Complex by Swanson Drug Interactions
HelloPharmacist Interaction Report
Swanson's Saw Palmetto Complex contains four active ingredients, and they do interact with a number of medications.
The most serious interaction involves lycopene and blood thinners (anticoagulants) or antiplatelet drugs — lycopene has antiplatelet effects in the lab, so taking it with these medications might theoretically increase your bleeding risk. That's a Moderate-severity concern.
Read the full breakdown — every affected drug type, severity by severity
Saw palmetto itself raises several other Moderate-severity flags. It may reduce how well birth control pills and estrogen therapy work because it has antiestrogenic effects.
It's also reported to prolong bleeding time, so it could increase bleeding risk with blood thinners or antiplatelet drugs alongside lycopene's effect. Pumpkin seed oil has one Moderate interaction: it may reduce how your body clears lithium, a mood stabilizer, which could raise lithium levels and require a dose adjustment.
Pygeum, the fourth ingredient, has no known interactions documented in our data. Altogether, these interactions span 175 individual medications.
If you take any prescription medication — especially blood thinners, birth control, estrogen, lithium, or mood stabilizers — run your exact medications through the checker below before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Saw Palmetto Complex?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Saw Palmetto Complex interact with 175 drugs. Click any drug to see the details.
3 of the 4 ingredients in Saw Palmetto Complex interact with drugs. Each result below shows which ingredient is responsible. Supercritical CO2 Saw Palmetto berry extract Lycopene Pumpkin seed Oil
AbciximabReoPro
How Abciximab interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
Supercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Abciximab interactionLycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Abrocitinib interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Abrocitinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
Supercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Acenocoumarol interactionLycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Acetaminophen, Aspirin interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Acetaminophen, Aspirin, Caffeine interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Acetaminophen, Ibuprofen interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Acetaminophen, Ibuprofen interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Acetylsalicylic Acid interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Acetylsalicylic Acid interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Alteplase, Tpa interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
Supercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Anacaulase-bcdb interactionLycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Anagrelide interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Anisindione interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Anisindione interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
Supercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Antithrombin Iii interactionLycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Apixaban interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
Supercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Argatroban interactionLycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAspirin, ButalbitalAxotal
How Aspirin, Butalbital interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Butalbital interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Butalbital interactionAspirin, Butalbital, CaffeineFiorinal
How Aspirin, Butalbital, Caffeine interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Butalbital, Caffeine interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Butalbital, Caffeine interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Butalbital, Caffeine, PhenacetinMarnal
How Aspirin, Butalbital, Caffeine, Phenacetin interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Butalbital, Caffeine, Phenacetin interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Butalbital, Caffeine, Phenacetin interactionAspirin, CaffeineAnacin
How Aspirin, Caffeine interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Caffeine interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Caffeine interactionAspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
How Aspirin, Caffeine, Codeine Phosphate interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Caffeine, Codeine Phosphate interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
How Aspirin, Caffeine, Dihydrocodeine Bitartrate interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAspirin, Caffeine, Dover's PwdAcedoval, Dovacet
How Aspirin, Caffeine, Dover's Pwd interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Caffeine, Dover's Pwd interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Caffeine, Dover's Pwd interactionAspirin, Caffeine, HydrocodoneDamason-P
How Aspirin, Caffeine, Hydrocodone interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
Supercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Caffeine, Hydrocodone interactionLycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Caffeine, Hydrocodone interactionAspirin, Caffeine, Isobutylallylbarbituric Acid, PhenacetinLanorinal
How Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interactionAspirin, Caffeine, OrphenadrineInvagesic, Invagesic Forte, Norgesic, Norgesic Forte, Orphengesic, Orphengesic Forte
How Aspirin, Caffeine, Orphenadrine interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Caffeine, Orphenadrine interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Caffeine, Orphenadrine interactionAspirin, Caffeine, Phenacetin, PropoxypheneMargesic Comp. 65
How Aspirin, Caffeine, Phenacetin, Propoxyphene interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Saw Palmetto Complex with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Supercritical CO2 Saw Palmetto berry extract
Anticoagulant/Antiplatelet Drugs
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Saw palmetto is reported to prolong bleeding time. Theoretically, it might increase the risk of bleeding when used concomitantly with anticoagulant or antiplatelet drugs.
Contraceptive Drugs
Saw palmetto might reduce the effectiveness of contraceptive drugs.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with contraceptive drugs taken concomitantly.
Estrogens
Saw palmetto might reduce the effectiveness of estrogens.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with estrogens taken concomitantly.
Lycopene
Anticoagulant/Antiplatelet Drugs
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
In vitro research shows that lycopene has antiplatelet effects.
Pumpkin seed Oil
Lithium
Pumpkin might reduce excretion and increase levels of lithium.
Pumpkin is thought to have diuretic properties. Theoretically, this might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
Brand information
Manufacturer and brand details for Saw Palmetto Complex, from the product label.
Swanson
See all Swanson products- Name
- Swanson Health Products
- City
- Fargo
- State
- ND
- ZipCode
- 58104
- Phone Number
- 1-800-437-4148
- Web Address
- www.swanson.com
Saw Palmetto Complex by Swanson: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Saw Palmetto Complex’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lycopene
Interacts with 122 drugsLycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible heart and prostate benefits, but evidence fr...
Read the full Lycopene monograph → Herb & supplement monographPumpkin
Interacts with 1 drugPumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The evidence for these uses is limited and...
Read the full Pumpkin monograph → Herb & supplement monographSaw Palmetto
Interacts with 174 drugsSaw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no better than a placebo for most men, though i...
Read the full Saw Palmetto monograph → Herb & supplement monographPygeum
Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some studies suggest modest benefit for these s...
Read the full Pygeum monograph →Sources & How We Checked
Saw Palmetto Complex's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lycopene 10 references
- Sharma, J. B., Kumar, A., Kumar, A., Malhotra, M., Arora, R., Prasad, S., and Batra, S. Effect of lycopene on pre-eclampsia and intra-uterine growth retardation in primigravidas. Int J Gynaecol.Obstet. 2003;81(3):257-262. PubMed
- Hsiao, G., Wang, Y., Tzu, N. H., Fong, T. H., Shen, M. Y., Lin, K. H., Chou, D. S., and Sheu, J. R. Inhibitory effects of lycopene on in vitro platelet activation and in vivo prevention of thrombus formation. J Lab Clin Med 2005;146(4):216-226. PubMed
- Clark, P. E., Hall, M. C., Borden, L. S., Jr., Miller, A. A., Hu, J. J., Lee, W. R., Stindt, D., D'Agostino, R., Jr., Lovato, J., Harmon, M., and Torti, F. M. Phase I-II prospective dose-escalating trial of lycopene in patients with biochemical relapse o
- O'Kennedy, N., Crosbie, L., Whelan, S., Luther, V., Horgan, G., Broom, J. I., Webb, D. J., and Duttaroy, A. K. Effects of tomato extract on platelet function: a double-blinded crossover study in healthy humans. Am.J.Clin.Nutr. 2006;84(3):561-569. PubMed
- Jatoi, A., Burch, P., Hillman, D., Vanyo, J. M., Dakhil, S., Nikcevich, D., Rowland, K., Morton, R., Flynn, P. J., Young, C., and Tan, W. A tomato-based, lycopene-containing intervention for androgen-independent prostate cancer: results of a Phase II stu
- Schwenke, C., Ubrig, B., Thurmann, P., Eggersmann, C., and Roth, S. Lycopene for advanced hormone refractory prostate cancer: a prospective, open phase II pilot study. J.Urol. 2009;181(3):1098-1103. PubMed
- Banerjee, S., Jeyaseelan, S., and Guleria, R. Trial of lycopene to prevent pre-eclampsia in healthy primigravidas: results show some adverse effects. J.Obstet.Gynaecol.Res. 2009;35(3):477-482. PubMed
- Haseen, F., Cantwell, M. M., O'Sullivan, J. M., and Murray, L. J. Is there a benefit from lycopene supplementation in men with prostate cancer? A systematic review. Prostate Cancer Prostatic.Dis. 2009;12(4):325-332. PubMed
- Ilic, D., Forbes, K. M., and Hassed, C. Lycopene for the prevention of prostate cancer. Cochrane.Database.Syst.Rev. 2011;(11):CD008007. PubMed
- Sawardekar SB, Patel TC, Uchil D. Comparative evaluation of antiplatelet effect of lycopene with aspirin and the effect of their combination on platelet aggregation: an in vitro study. Indian J Pharmacol 2016;48:26-31. PubMed
Pumpkin 5 references
- Marks L, Partin AW, Epstein JI, et al. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol 2000;163:1451-6. DOI
- Cho YH, Lee SY, Jeong DW, et al. Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evid Based Complement Alternat Med 2014;2014:549721. PubMed
- Vahlensieck W, Theurer C, Pfitzer E, Patz B, Banik N, Engelmann U. Effects of pumpkin seed in men with lower urinary tract symptoms due to benign prostatic hyperplasia in the one-year, randomized, placebo-controlled GRANU study. Urol Int 2015;94(3):286-95 PubMed
- Assouly P. Hair loss associated with cucurbit poisoning. JAMA Dermatol. 2018 May 1;154(5):617-618. PubMed
- Gawryjolek J, Ludwig H, Zbikowska-Götz M, Bartuzi Z, Krogulska A. Anaphylaxis after consumption of pumpkin seeds in a 2-y-old child tolerant to its pulp: A case study. Nutrition 2021;89:111272. PubMed
Saw Palmetto 22 references
- Wilt TJ, Ishani A, Stark G, et al. Saw palmetto extracts for treatment of benign prostatic hyperplasia: a systematic review. JAMA 1998;280:1604-9. PubMed
- Carraro JC, Raynaud JP, Koch G, et al. Comparison of phytotherapy (Permixon) with finasteride in the treatment of benign prostate hyperplasia: a randomized international study of 1,098 patients. Prostate 1996;29:231-40. DOI
- Di Silverio F, D'Eramo G, Lubrano C, et al. Evidence that Serenoa repens extract displays an antiestrogenic activity in prostatic tissue of benign prostatic hypertrophy patients. Eur Urol 1992;21:309-14. PubMed
- Stepanov VN, Siniakova LA, Sarrazin B, Raynaud JP. Efficacy and tolerability of the lipidosterolic extract of Serenoa repens (Permixon) in benign prostatic hyperplasia: a double-blind comparison of two dosage regimens. Adv Ther 1999;16:231-41.
- Cheema P, El-Mefty O, Jazieh AR. Intraoperative haemorrhage associated with the use of extract of Saw Palmetto herb: a case report and review of literature. J Intern Med 2001;250:167-9. PubMed
- Jibrin I, Erinle A, Saidi A, Aliyu ZY. Saw palmetto-induced pancreatitis. South Med J 2006;99:611-2. PubMed
- Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
- Avins AL, Bent S, Staccone S, et al. A detailed safety assessment of a saw palmetto extract. Complement Ther Med 2008;16:147-54. PubMed
- Morgia, G., Mucciardi, G., Gali, A., Madonia, M., Marchese, F., Di, Benedetto A., Romano, G., Bonvissuto, G., Castelli, T., Macchione, L., and Magno, C. Treatment of chronic prostatitis/chronic pelvic pain syndrome category IIIA with Serenoa repens plus
- Aliaev, IuG, Vinarov, A. Z., Lokshin, K. L., and Spivak, L. G. [Efficiency and safety of prostamol-Uno in patients with chronic abacterial prostatitis]. Urologiia. 2006;(1):47-50.
- Agbabiaka, T. B., Pittler, M. H., Wider, B., and Ernst, E. Serenoa repens (saw palmetto): a systematic review of adverse events. Drug Saf 2009;32(8):637-647. PubMed
- Wargo, K. A., Allman, E., and Ibrahim, F. A possible case of saw palmetto-induced pancreatitis. South.Med.J. 2010;103(7):683-685. PubMed
- Lapi, F., Gallo, E., Giocaliere, E., Vietri, M., Baronti, R., Pieraccini, G., Tafi, A., Menniti-Ippolito, F., Mugelli, A., Firenzuoli, F., and Vannacci, A. Acute liver damage due to Serenoa repens: a case report. Br.J.Clin.Pharmacol. 2010;69(5):558-560.
- Mantovani, F. Serenoa repens in benign prostatic hypertrophy: analysis of 2 Italian studies. Minerva Urol.Nefrol. 2010;62(4):335-340.
- Hanaka, M., Yoshii, C., Yatera, K., Ito, C., Chojin, Y., Nagata, S., Yamasaki, K., Nishida, C., Kawanami, T., Kawanami, Y., Ishimoto, H., and Mukae, H. [A case of rhabdomyolysis caused by saw palmetto of healthy foods]. J.UOEH. 6-1-2012;34(2):193-199. PubMed
- Miroddi, M., Carni, A., Mannucci, C., Moleti, M., Navarra, M., and Calapai, G. Hot flashes in a young girl: a wake-up call concerning Serenoa repens use in children. Pediatrics 2012;130(5):e1374-e1376.
- Braeckman J. The extract of Serenoa repens in the treatment of benign prostatic hyperplasia: a multicenter open study. Current Therapeutic Research 1994;55(7):776-785. DOI
- Jipescu D, Patel A, Bohra H, Pientka A. Rare case of saw palmetto induced heart block. JACC 2017;69(11) supplement:2310.
- Morabito P, Miroddi M, Giovinazzo S, Spina E, Calapai G. Serenoa repens as an endocrine disruptor in a 10-year-Old young girl: a new case report. Pharmacology. 2015;96(1-2):41-3. doi: 10.1159/000431327.
- Gammoudi R, Ameur K, Ouni B, et al. Fixed drug eruption to Serenoa repens: first case report and consideration of the use of herbal medicine. Dermatol Ther 2020 Aug 29:e14247.
- Paulis G, Paulis A, Perletti G. Serenoa repens and its effects on male sexual function. A systematic review and meta-analysis of clinical trials. Arch Ital Urol Androl 2021;93(4):475-480. PubMed
- Venkateswaran S, Declet-Bauzo R, Shodeinde M, Gilford P. Postoperative Retroperitoneal Hematoma: A Case of Saw Palmetto and the Importance of Primary Care Intervention. HCA Healthc J Med 2020;1(5):279-282. PubMed
Pygeum 3 references
- Ishani A, MacDonald R, Nelson D, et al. Pygeum africanum for the treatment of patients with benign prostatic hyperplasia: a systematic review and quantitative meta-analysis. Am J Med 2000;109:654-64.. PubMed
- Wilt T, Ishani A, Mac Donald R, et al. Pygeum africanum for benign prostatic hyperplasia. Cochrane Database Syst Rev 2002;CD001044.. PubMed
- Andro M and Riffaud J. Pygeum africanum extract for the treatment of patients with benign prostatic hyperplasia: a review of 25 years of published experience. Curr Ther Res 1995;56(8):796-817. DOI
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC