Saw Palmetto Complex Ingredients & Drug Interactions
by Swanson
What is this page for?
First and foremost: checking Saw Palmetto Complex against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Saw Palmetto Complex is a dietary supplement by Swanson with 4 active ingredients. Its ingredients are commonly taken for heart health, prostate health, antioxidant support.Based on those ingredients, 175 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Supercritical CO2 Saw Palmetto berry extract, Lycopene, Pumpkin seed Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Saw Palmetto Complex by Swanson
Ask about any prescription or over-the-counter medication and we check it for interactions with Saw Palmetto Complex by Swanson — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Saw Palmetto Complex by Swanson
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This softgel contains four active ingredients: lycopene, pumpkin seed oil, a supercritical CO2 extract of saw palmetto berries, and pygeum extract. Lycopene is a carotenoid (plant pigment) with antioxidant properties.
Pumpkin seed oil is included for potential urinary and prostate support. Saw palmetto berry extract and pygeum extract are both traditionally used for prostate and urinary tract health.
The capsule itself is made from gelatin, glycerin, soybean oil, beeswax, and other inactive ingredients including soy lecithin and carob for color and texture.
Does it work?
Strong evidence
Evidence for this product's individual ingredients varies widely. Pygeum extract is likely effective for benign prostatic hyperplasia (BPH, an enlarged prostate).
Pumpkin seed oil is possibly effective for BPH as well. Lycopene is possibly effective for prostate cancer prevention but possibly ineffective for bladder cancer and diabetes.
Saw palmetto is possibly ineffective for BPH—despite its popularity for this use, the evidence doesn't clearly support it. For many other claimed uses across these ingredients (alopecia, cystitis, asthma), the evidence is too limited to rate.
How safe is it?
Well-documented data
Saw palmetto extract is the main safety concern in this product: the facts rate it likely unsafe in pregnancy due to possible hormonal effects and insufficient safety data, and advise avoiding it while breastfeeding. Lycopene supplements are generally well tolerated but should be avoided in pregnancy unless your doctor advises it; there isn't enough data on safety while breastfeeding.
Pumpkin seed oil is considered safe as food but concentrated supplements lack safety data in pregnancy and breastfeeding—discuss with your doctor or pharmacist if you're pregnant or nursing. Pygeum also lacks established safe use in pregnancy and should be avoided while breastfeeding.
Common side effects reported with these ingredients include gastrointestinal upset (diarrhea, nausea, abdominal discomfort) and, with saw palmetto, dizziness, headache, or decreased libido. Rare but serious effects have been documented: anaphylaxis with pumpkin products, and heart rhythm problems with saw palmetto.
Meds to double-check
Moderate interaction found
Before taking this product, check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (like warfarin, clopidogrel, or aspirin in higher doses)—lycopene and saw palmetto may increase bleeding risk. If you take birth control pills or estrogen therapy, saw palmetto might reduce their effectiveness.
If you take lithium, pumpkin seed oil may raise lithium levels dangerously. Women taking any hormonal medications should avoid this product altogether.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is designed for men's prostate and urinary health, though evidence for some ingredients is weak. It carries real interactions with blood thinners, birth control, estrogen, and lithium—all Moderate severity.
Women should avoid it entirely due to hormonal effects and lack of pregnancy/breastfeeding safety data. Men taking any of those medication types, or with any chronic health condition, should check their specific drugs with their doctor or pharmacist before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Saw Palmetto Complex, straight from the product label.
| Brand | Swanson |
|---|---|
| Barcode (UPC) | 087614020136 |
| Net contents | 60 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Jun 24, 2019 |
| DSLD ID | 204119 |
| Product type | Other Combinations |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult Male (18-50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Saw Palmetto Complex by Swanson, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Lycopene | 5 mg | -- |
| Pumpkin seed Oil | 40 mg | -- |
| Supercritical CO2 Saw Palmetto berry extract | 160 mg | -- |
| Pygeum extract | 50 mg | -- |
Other ingredients: Gelatin, Glycerin, Soybean Oil, yellow Beeswax, purified Water, Carob, Soy Lecithin, Titanium Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, take one softgel two times per day with food and water.
Precautions
Warning: For adults only.
Consult your physician before using this or any product if you are pregnant or nursing, taking medication or have a medical condition.
Keep out of reach of children.
Do not use if seal is broken.
Contains soy.
Storage
Store in a cool, dry place. Do not refrigerate.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formula
Prostate Health
Contains soy.
General Statements
Comprehensive formula
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Saw Palmetto Complex by Swanson label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Saw Palmetto Complex by Swanson
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Lycopene
Interacts with122 drugs
Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible hear...
Lycopene monograph & interactionsPumpkin seed Oil
Interacts with1 drug
Pumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The...
Pumpkin seed Oil monograph & interactionsSupercritical CO2 Saw Palmetto berry extract
Interacts with174 drugs
Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no bett...
Supercritical CO2 Saw Palmetto berry extract monograph & interactionsPygeum extract
No knowninteractions
Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some st...
Pygeum extract monograph & interactionsOther (inactive) ingredients: Gelatin, Glycerin, Soybean Oil, Yellow Beeswax, Purified Water, Carob, Soy Lecithin, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.
Saw Palmetto Complex by Swanson Drug Interactions
HelloPharmacist Interaction Report
Swanson's Saw Palmetto Complex interacts with medications through its lycopene, pumpkin seed oil, and saw palmetto berry extract.
The most serious concern is a Moderate-severity interaction: saw palmetto might reduce how well estrogens and birth control pills work, because it may have antiestrogenic effects that could interfere with these drugs.
Read the full breakdown — every affected drug type, severity by severity
Lycopene and saw palmetto both carry Moderate risks with blood thinners (anticoagulants and antiplatelet drugs). Lycopene has antiplatelet effects that might increase bleeding risk.
Saw palmetto is reported to prolong bleeding time, which could raise bleeding risk further when combined with these medications. Pumpkin seed oil presents a separate Moderate concern: it may reduce the excretion of lithium, potentially raising lithium levels to unsafe amounts.
Pygeum extract, the fourth ingredient, has no documented interactions in our data. Altogether, these interactions span 175 individual medications.
Use the medication checker on this page to see if any of your specific drugs are affected, and discuss the results with your doctor or pharmacist before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Saw Palmetto Complex?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Saw Palmetto Complex interact with 175 drugs. Click any drug to see the details.
3 of the 4 ingredients in Saw Palmetto Complex interact with drugs. Each result below shows which ingredient is responsible. Supercritical CO2 Saw Palmetto berry extract Lycopene Pumpkin seed Oil
Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium OxideBufferin
How Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interactionAspirin, CarisoprodolSoma Compound
How Aspirin, Carisoprodol interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Carisoprodol interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Carisoprodol interactionAspirin, Carisoprodol, Codeine PhosphateSoma Compound w/ Codeine
How Aspirin, Carisoprodol, Codeine Phosphate interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Carisoprodol, Codeine Phosphate interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Carisoprodol, Codeine Phosphate interactionAspirin, Chlorpheniramine, PhenylpropanolamineAlka-Seltzer Plus Cold
How Aspirin, Chlorpheniramine, Phenylpropanolamine interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Chlorpheniramine, Phenylpropanolamine interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Chlorpheniramine, Phenylpropanolamine interactionAspirin, Citric Acid, Sodium BicarbonateAlka-Seltzer Pain Reliever and Antacid
How Aspirin, Citric Acid, Sodium Bicarbonate interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Citric Acid, Sodium Bicarbonate interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Citric Acid, Sodium Bicarbonate interactionAspirin, Codeine PhosphateAspirin w/ Codeine
How Aspirin, Codeine Phosphate interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Codeine Phosphate interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Codeine Phosphate interactionAspirin, Codeine Phosphate, MethocarbamolRobaxisal C
How Aspirin, Codeine Phosphate, Methocarbamol interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Codeine Phosphate, Methocarbamol interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Codeine Phosphate, Methocarbamol interactionAspirin, Codeine Phosphate, PhenobarbitalPhenaphen
How Aspirin, Codeine Phosphate, Phenobarbital interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Codeine Phosphate, Phenobarbital interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Codeine Phosphate, Phenobarbital interactionAspirin, Diphenhydramine, PhenylpropanolamineAlka Seltzer Plus Night Time Effervescent
How Aspirin, Diphenhydramine, Phenylpropanolamine interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Diphenhydramine, Phenylpropanolamine interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Diphenhydramine, Phenylpropanolamine interactionAspirin, DipyridamoleAggrenox, Asasantin Retard
How Aspirin, Dipyridamole interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
Supercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Dipyridamole interactionLycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Dipyridamole interactionAspirin, Ethoheptazine, MeprobamateEquagesic
How Aspirin, Ethoheptazine, Meprobamate interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Ethoheptazine, Meprobamate interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Ethoheptazine, Meprobamate interactionAspirin, HydrocodoneAlor 5 500, Lortab ASA
How Aspirin, Hydrocodone interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Hydrocodone interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Hydrocodone interactionAspirin, MeprobamateMicrainin
How Aspirin, Meprobamate interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Meprobamate interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Meprobamate interactionAspirin, MethocarbamolRobaxisal
How Aspirin, Methocarbamol interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Methocarbamol interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Methocarbamol interactionAspirin, OmeprazoleYosprala
How Aspirin, Omeprazole interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Omeprazole interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Omeprazole interactionAspirin, OxycodonePercodan
How Aspirin, Oxycodone interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
Supercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Oxycodone interactionLycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Oxycodone interactionAspirin, PentazocineTalwin Compound
How Aspirin, Pentazocine interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Aspirin, Pentazocine interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Aspirin, Pentazocine interactionBazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with Saw Palmetto Complex — through 1 ingredient. Tap an ingredient for the detail:
Supercritical Co2 Saw Palmetto Berry ExtractEstrogens Moderate
Interaction Summary
Saw palmetto might reduce the effectiveness of estrogens.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Bazedoxifene Acetate, Conjugated Estrogens interactionBetrixabanBevyxxa
How Betrixaban interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Betrixaban interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Betrixaban interactionBirth Control PillsBirth control pills
How Birth Control Pills interacts with Saw Palmetto Complex — through 1 ingredient. Tap an ingredient for the detail:
Supercritical Co2 Saw Palmetto Berry ExtractContraceptive Drugs Moderate
Interaction Summary
Saw palmetto might reduce the effectiveness of contraceptive drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Birth Control Pills interactionBivalirudinAngiomax, Angiomax Rtu, Angiox
How Bivalirudin interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Bivalirudin interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Bivalirudin interactionBromfenac SodiumBromsite, Prolensa
How Bromfenac Sodium interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
Supercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Bromfenac Sodium interactionLycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Bromfenac Sodium interactionCabliviCablivi
How Cablivi interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Cablivi interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Cablivi interactionCangrelorKengreal
How Cangrelor interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
Supercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Cangrelor interactionLycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Cangrelor interactionCilostazolPletal
How Cilostazol interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
LycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Cilostazol interactionSupercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Cilostazol interactionClopidogrelPlavix
How Clopidogrel interacts with Saw Palmetto Complex — through 2 ingredients. Tap an ingredient for the detail:
Supercritical Co2 Saw Palmetto Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Clopidogrel interactionLycopeneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Lycopene + Clopidogrel interactionConjugated EstrogensCenestin, Enjuvia, Premarin, Premarin Vaginal Cream
How Conjugated Estrogens interacts with Saw Palmetto Complex — through 1 ingredient. Tap an ingredient for the detail:
Supercritical Co2 Saw Palmetto Berry ExtractEstrogens Moderate
Interaction Summary
Saw palmetto might reduce the effectiveness of estrogens.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Conjugated Estrogens interactionConjugated Estrogens, Medroxyprogesterone AcetatePremplus, Prempro
How Conjugated Estrogens, Medroxyprogesterone Acetate interacts with Saw Palmetto Complex — through 1 ingredient. Tap an ingredient for the detail:
Supercritical Co2 Saw Palmetto Berry ExtractEstrogens Moderate
Interaction Summary
Saw palmetto might reduce the effectiveness of estrogens.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Conjugated Estrogens, Medroxyprogesterone Acetate interactionConjugated Estrogens, MeprobamatePMB 200, PMB 400
How Conjugated Estrogens, Meprobamate interacts with Saw Palmetto Complex — through 1 ingredient. Tap an ingredient for the detail:
Supercritical Co2 Saw Palmetto Berry ExtractEstrogens Moderate
Interaction Summary
Saw palmetto might reduce the effectiveness of estrogens.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Conjugated Estrogens, Meprobamate interactionConjugated Estrogens, MethyltestosteronePremarin with Methyltestosterone
How Conjugated Estrogens, Methyltestosterone interacts with Saw Palmetto Complex — through 1 ingredient. Tap an ingredient for the detail:
Supercritical Co2 Saw Palmetto Berry ExtractEstrogens Moderate
Interaction Summary
Saw palmetto might reduce the effectiveness of estrogens.
Read the full Supercritical Co2 Saw Palmetto Berry Extract + Conjugated Estrogens, Methyltestosterone interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Saw Palmetto Complex with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Supercritical CO2 Saw Palmetto berry extract
Anticoagulant/Antiplatelet Drugs
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Saw palmetto is reported to prolong bleeding time. Theoretically, it might increase the risk of bleeding when used concomitantly with anticoagulant or antiplatelet drugs.
Contraceptive Drugs
Saw palmetto might reduce the effectiveness of contraceptive drugs.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with contraceptive drugs taken concomitantly.
Estrogens
Saw palmetto might reduce the effectiveness of estrogens.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with estrogens taken concomitantly.
Lycopene
Anticoagulant/Antiplatelet Drugs
Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
In vitro research shows that lycopene has antiplatelet effects.
Pumpkin seed Oil
Lithium
Pumpkin might reduce excretion and increase levels of lithium.
Pumpkin is thought to have diuretic properties. Theoretically, this might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
Brand information
Manufacturer and brand details for Saw Palmetto Complex, from the product label.
Swanson
See all Swanson products- Name
- Swanson Health Products
- City
- Fargo
- State
- ND
- ZipCode
- 58104
- Phone Number
- 1-800-437-4148
- Web Address
- www.swanson.com
Saw Palmetto Complex by Swanson: Common Questions
Does Saw Palmetto Complex by Swanson interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
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Will this affect my birth control?
What's the evidence that this actually works for prostate health?
What side effects should I watch for?
Is this product gluten-free or vegan?
What's the difference between the saw palmetto in this product and regular saw palmetto?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Saw Palmetto Complex’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lycopene
Interacts with 122 drugsLycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible heart and prostate benefits, but evidence fr...
Read the full Lycopene monograph → Herb & supplement monographPumpkin
Interacts with 1 drugPumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The evidence for these uses is limited and...
Read the full Pumpkin monograph → Herb & supplement monographSaw Palmetto
Interacts with 174 drugsSaw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no better than a placebo for most men, though i...
Read the full Saw Palmetto monograph → Herb & supplement monographPygeum
Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some studies suggest modest benefit for these s...
Read the full Pygeum monograph →Sources & How We Checked
Saw Palmetto Complex's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lycopene 10 references
- Sharma, J. B., Kumar, A., Kumar, A., Malhotra, M., Arora, R., Prasad, S., and Batra, S. Effect of lycopene on pre-eclampsia and intra-uterine growth retardation in primigravidas. Int J Gynaecol.Obstet. 2003;81(3):257-262. PubMed
- Hsiao, G., Wang, Y., Tzu, N. H., Fong, T. H., Shen, M. Y., Lin, K. H., Chou, D. S., and Sheu, J. R. Inhibitory effects of lycopene on in vitro platelet activation and in vivo prevention of thrombus formation. J Lab Clin Med 2005;146(4):216-226. PubMed
- Clark, P. E., Hall, M. C., Borden, L. S., Jr., Miller, A. A., Hu, J. J., Lee, W. R., Stindt, D., D'Agostino, R., Jr., Lovato, J., Harmon, M., and Torti, F. M. Phase I-II prospective dose-escalating trial of lycopene in patients with biochemical relapse o
- O'Kennedy, N., Crosbie, L., Whelan, S., Luther, V., Horgan, G., Broom, J. I., Webb, D. J., and Duttaroy, A. K. Effects of tomato extract on platelet function: a double-blinded crossover study in healthy humans. Am.J.Clin.Nutr. 2006;84(3):561-569. PubMed
- Jatoi, A., Burch, P., Hillman, D., Vanyo, J. M., Dakhil, S., Nikcevich, D., Rowland, K., Morton, R., Flynn, P. J., Young, C., and Tan, W. A tomato-based, lycopene-containing intervention for androgen-independent prostate cancer: results of a Phase II stu
- Schwenke, C., Ubrig, B., Thurmann, P., Eggersmann, C., and Roth, S. Lycopene for advanced hormone refractory prostate cancer: a prospective, open phase II pilot study. J.Urol. 2009;181(3):1098-1103. PubMed
- Banerjee, S., Jeyaseelan, S., and Guleria, R. Trial of lycopene to prevent pre-eclampsia in healthy primigravidas: results show some adverse effects. J.Obstet.Gynaecol.Res. 2009;35(3):477-482. PubMed
- Haseen, F., Cantwell, M. M., O'Sullivan, J. M., and Murray, L. J. Is there a benefit from lycopene supplementation in men with prostate cancer? A systematic review. Prostate Cancer Prostatic.Dis. 2009;12(4):325-332. PubMed
- Ilic, D., Forbes, K. M., and Hassed, C. Lycopene for the prevention of prostate cancer. Cochrane.Database.Syst.Rev. 2011;(11):CD008007. PubMed
- Sawardekar SB, Patel TC, Uchil D. Comparative evaluation of antiplatelet effect of lycopene with aspirin and the effect of their combination on platelet aggregation: an in vitro study. Indian J Pharmacol 2016;48:26-31. PubMed
Pumpkin 5 references
- Marks L, Partin AW, Epstein JI, et al. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol 2000;163:1451-6. DOI
- Cho YH, Lee SY, Jeong DW, et al. Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evid Based Complement Alternat Med 2014;2014:549721. PubMed
- Vahlensieck W, Theurer C, Pfitzer E, Patz B, Banik N, Engelmann U. Effects of pumpkin seed in men with lower urinary tract symptoms due to benign prostatic hyperplasia in the one-year, randomized, placebo-controlled GRANU study. Urol Int 2015;94(3):286-95 PubMed
- Assouly P. Hair loss associated with cucurbit poisoning. JAMA Dermatol. 2018 May 1;154(5):617-618. PubMed
- Gawryjolek J, Ludwig H, Zbikowska-Götz M, Bartuzi Z, Krogulska A. Anaphylaxis after consumption of pumpkin seeds in a 2-y-old child tolerant to its pulp: A case study. Nutrition 2021;89:111272. PubMed
Saw Palmetto 22 references
- Wilt TJ, Ishani A, Stark G, et al. Saw palmetto extracts for treatment of benign prostatic hyperplasia: a systematic review. JAMA 1998;280:1604-9. PubMed
- Carraro JC, Raynaud JP, Koch G, et al. Comparison of phytotherapy (Permixon) with finasteride in the treatment of benign prostate hyperplasia: a randomized international study of 1,098 patients. Prostate 1996;29:231-40. DOI
- Di Silverio F, D'Eramo G, Lubrano C, et al. Evidence that Serenoa repens extract displays an antiestrogenic activity in prostatic tissue of benign prostatic hypertrophy patients. Eur Urol 1992;21:309-14. PubMed
- Stepanov VN, Siniakova LA, Sarrazin B, Raynaud JP. Efficacy and tolerability of the lipidosterolic extract of Serenoa repens (Permixon) in benign prostatic hyperplasia: a double-blind comparison of two dosage regimens. Adv Ther 1999;16:231-41.
- Cheema P, El-Mefty O, Jazieh AR. Intraoperative haemorrhage associated with the use of extract of Saw Palmetto herb: a case report and review of literature. J Intern Med 2001;250:167-9. PubMed
- Jibrin I, Erinle A, Saidi A, Aliyu ZY. Saw palmetto-induced pancreatitis. South Med J 2006;99:611-2. PubMed
- Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
- Avins AL, Bent S, Staccone S, et al. A detailed safety assessment of a saw palmetto extract. Complement Ther Med 2008;16:147-54. PubMed
- Morgia, G., Mucciardi, G., Gali, A., Madonia, M., Marchese, F., Di, Benedetto A., Romano, G., Bonvissuto, G., Castelli, T., Macchione, L., and Magno, C. Treatment of chronic prostatitis/chronic pelvic pain syndrome category IIIA with Serenoa repens plus
- Aliaev, IuG, Vinarov, A. Z., Lokshin, K. L., and Spivak, L. G. [Efficiency and safety of prostamol-Uno in patients with chronic abacterial prostatitis]. Urologiia. 2006;(1):47-50.
- Agbabiaka, T. B., Pittler, M. H., Wider, B., and Ernst, E. Serenoa repens (saw palmetto): a systematic review of adverse events. Drug Saf 2009;32(8):637-647. PubMed
- Wargo, K. A., Allman, E., and Ibrahim, F. A possible case of saw palmetto-induced pancreatitis. South.Med.J. 2010;103(7):683-685. PubMed
- Lapi, F., Gallo, E., Giocaliere, E., Vietri, M., Baronti, R., Pieraccini, G., Tafi, A., Menniti-Ippolito, F., Mugelli, A., Firenzuoli, F., and Vannacci, A. Acute liver damage due to Serenoa repens: a case report. Br.J.Clin.Pharmacol. 2010;69(5):558-560.
- Mantovani, F. Serenoa repens in benign prostatic hypertrophy: analysis of 2 Italian studies. Minerva Urol.Nefrol. 2010;62(4):335-340.
- Hanaka, M., Yoshii, C., Yatera, K., Ito, C., Chojin, Y., Nagata, S., Yamasaki, K., Nishida, C., Kawanami, T., Kawanami, Y., Ishimoto, H., and Mukae, H. [A case of rhabdomyolysis caused by saw palmetto of healthy foods]. J.UOEH. 6-1-2012;34(2):193-199. PubMed
- Miroddi, M., Carni, A., Mannucci, C., Moleti, M., Navarra, M., and Calapai, G. Hot flashes in a young girl: a wake-up call concerning Serenoa repens use in children. Pediatrics 2012;130(5):e1374-e1376.
- Braeckman J. The extract of Serenoa repens in the treatment of benign prostatic hyperplasia: a multicenter open study. Current Therapeutic Research 1994;55(7):776-785. DOI
- Jipescu D, Patel A, Bohra H, Pientka A. Rare case of saw palmetto induced heart block. JACC 2017;69(11) supplement:2310.
- Morabito P, Miroddi M, Giovinazzo S, Spina E, Calapai G. Serenoa repens as an endocrine disruptor in a 10-year-Old young girl: a new case report. Pharmacology. 2015;96(1-2):41-3. doi: 10.1159/000431327.
- Gammoudi R, Ameur K, Ouni B, et al. Fixed drug eruption to Serenoa repens: first case report and consideration of the use of herbal medicine. Dermatol Ther 2020 Aug 29:e14247.
- Paulis G, Paulis A, Perletti G. Serenoa repens and its effects on male sexual function. A systematic review and meta-analysis of clinical trials. Arch Ital Urol Androl 2021;93(4):475-480. PubMed
- Venkateswaran S, Declet-Bauzo R, Shodeinde M, Gilford P. Postoperative Retroperitoneal Hematoma: A Case of Saw Palmetto and the Importance of Primary Care Intervention. HCA Healthc J Med 2020;1(5):279-282. PubMed
Pygeum 3 references
- Ishani A, MacDonald R, Nelson D, et al. Pygeum africanum for the treatment of patients with benign prostatic hyperplasia: a systematic review and quantitative meta-analysis. Am J Med 2000;109:654-64.. PubMed
- Wilt T, Ishani A, Mac Donald R, et al. Pygeum africanum for benign prostatic hyperplasia. Cochrane Database Syst Rev 2002;CD001044.. PubMed
- Andro M and Riffaud J. Pygeum africanum extract for the treatment of patients with benign prostatic hyperplasia: a review of 25 years of published experience. Curr Ther Res 1995;56(8):796-817. DOI
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC