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Dietary supplement

Stevia Extract Ingredients & Drug Interactions

by NOW

Stevia Extract label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Stevia Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Stevia Extract is a dietary supplement by NOW with 1 active ingredient. Its ingredients are commonly taken for sugar substitute / sweetener, blood sugar support in diabetes, weight management.Based on those ingredients, 259 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are certified organic Stevia extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Stevia Extract by NOW

Ask about any prescription or over-the-counter medication and we check it for interactions with Stevia Extract by NOW — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Stevia Extract by NOW

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 17, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: certified organic stevia extract. Stevia is a zero-calorie sweetener derived from stevia plant leaves.

The liquid formulation also includes distilled water and 10% organic alcohol as inactive ingredients to preserve and deliver the extract.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Stevia product and its label doesn't state a use — see Stevia's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The data we hold shows insufficient reliable evidence to rate stevia extract for diabetes, hypertension, or weight management. While preliminary research suggests a single dose of stevia extract may reduce blood sugar levels after meals in people with type 2 diabetes, the overall body of evidence isn't strong enough to confirm it works for these purposes.

The evidence, ingredient by ingredient Stevia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Purified stevia sweeteners in typical food amounts are generally recognized as safe. However, this product is a supplement dose rather than a food amount, and whole-leaf or high-dose stevia supplements lack robust safety data—so caution is warranted.

Most people tolerate stevia and its steviol glycosides well, with minor side effects like abdominal bloating, dizziness, headache, muscle pain, nausea, and numbness typically resolving within the first week. Allergic reactions are rare but possible.

Side effects, ingredient by ingredient Stevia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Stevia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 259 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take lithium (moderate interaction concern), blood pressure medications, or diabetes drugs (minor interactions). These are the medication types where interactions are documented.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

NOW Stevia Extract is a zero-calorie sweetener supplement, but it interacts with lithium and may affect blood pressure and diabetes medications. If you take any of those drug types, talk with your doctor or pharmacist before starting this product.

Otherwise, it's generally well tolerated, though long-term safety data for supplement doses is limited.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 23, 2011.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Stevia Extract, straight from the product label.

Brand NOW
Barcode (UPC) 733739069801
Net contents 2 fl. Oz.; 60 mL
Market status On market
Date entered into DSLD Dec 23, 2011
DSLD ID 2849
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Stevia Extract by NOW, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.0325 mL
Maximum serving Sizes:
0.13 mL
Servings per container
461
UPC/BARCODE
733739069801
IngredientAmount% DV
certified organic Stevia extract50 mg--

Other ingredients: distilled Water, 10% Organic Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Suggested/Recommended/Usage/Directions

SUGGESTED USAGE: As a dietary supplement, take 1 to 4 drops as desired daily. Sedimentation may occur. Shake well before using.

Storage

Store in a cool, dry place. Please Recycle.

General

CODE 6980 V3

General Statements

Liquid Extract

Net

Non-Bitter

This product is intended for dietary supplement purposes only. Stevia rebaudiana is a natural herb that grows in Asia and South America.

Formulation

Vegetarian Product

Vegetarian/Vegan Product.

Contains no salt, yeast, wheat, gluten, soy, milk, egg, shellfish, preservatives, artificial colors, artificial flavors, or artificial sweeteners.

Certified Organic

Certified Organic by Quality Assurance International

Certified Organic

Seals/Symbols

QUALITY GMP ASSURED

USDA ORGANIC

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Stevia Extract by NOW label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Stevia Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Stevia Extract by NOW

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.0325 mL Dosage formLiquid Servings per container461 Amounts shown are per serving.

Certified organic Stevia extract

Interacts with
259 drugs
50 mg per serving

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regu...

Certified organic Stevia extract monograph & interactions

Other (inactive) ingredients: Distilled Water, 10% Organic Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Stevia Extract by NOW Drug Interactions

Want to check YOUR meds against Stevia Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
259Drugs
1 Moderate 258 Minor

Ingredients driving the most interactions

certified organic Stevia extract 259

Individual Drug Interactions

The ingredients in Stevia Extract interact with 259 drugs. Click any drug to see the details.

1 of the 1 ingredient in Stevia Extract interact with drugs. Each result below shows which ingredient is responsible. certified organic Stevia extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Stevia Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

certified organic Stevia extract3 drug types · 259 drugs

Lithium

Theoretically, stevia might decrease clearance and increase levels of lithium.
Animal research suggests that stevia extracts might have diuretic activity. Theoretically, increased reabsorption of lithium along with sodium might reduce excretion and increase levels of lithium.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Preliminary clinical research in patients with type 2 diabetes suggests that taking a single dose of stevia extract 1000 mg reduces postprandial blood glucose levels when taken with a meal. However, other clinical research in patients with type 1 or type 2 diabetes suggests that taking stevioside 250 mg three times daily does not significantly affect blood glucose levels or glycated hemoglobin (HbA1C) after three months of treatment.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Stevia extract and stevioside might lower blood pressure in patients with hypertension. However, other clinical research suggests that stevioside does not significantly lower blood pressure in patients with hypertension.

Likelihood Possible Evidence D
certified organic Stevia extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Stevia Extract, from the product label.

NOW

See all NOW products
Name
NOW FOODS
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Web Address
www.nowfoods.com
Pharmacist Counseling Corner

Stevia Extract by NOW: Common Questions

Does Stevia Extract by NOW interact with any medications?
Yes. Based on its ingredients, Stevia Extract has a known interaction with 259 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Stevia Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use this if I take lithium?
Not without talking to your doctor first. Stevia might reduce how your body clears lithium, raising its levels. This is a moderate interaction concern and needs medical review of your specific situation.
What side effects might I experience?
Common minor ones—abdominal bloating, dizziness, headache, muscle pain, nausea, numbness—usually go away after the first week. Allergic reactions are rare. Most people tolerate stevia well.
Is stevia safe during pregnancy or while breastfeeding?
The safety data we have doesn't address pregnancy or breastfeeding with this product. Talk with your doctor or pharmacist about whether it's right for you in those situations.
Does this actually work for diabetes or blood pressure?
The evidence isn't strong enough yet to say. One small study showed stevia might lower blood glucose after meals, but overall the data is insufficient to confirm it works for diabetes, high blood pressure, or weight loss.
What's the difference between this supplement and stevia in food or beverages?
Food amounts of purified stevia are generally recognized as safe, but this is a supplement dose. Supplement-level doses of stevia haven't been as thoroughly studied, so the safety profile is less certain—that's why caution is advised.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Stevia Extract label
Go deeper

The Full Monographs Behind Stevia Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Stevia

Interacts with 259 drugs

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regulators. Purified stevia extracts have a...

Read the full Stevia monograph →
Sources

Sources & How We Checked

Stevia Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Stevia 10 references
  1. Chan P, Xu DY, Liu JC, et al. The effect of stevioside on blood pressure and plasma catecholamines in spontaneously hypertensive rats. Life Sci 1998;63:1679-84. PubMed
  2. Melis MS. A crude extract of Stevia rebaudiana increases the renal plasma flow of normal and hypertensive rats. Braz J Med Biol Res 1996;29:669-75.
  3. Melis MS. Chronic administration of aqueous extract of Stevia rebaudiana in rats: renal effects. J Ethnopharmacol 1995;47:129-34. PubMed
  4. Melis MS, Sainati AR. Effect of calcium and verapamil on renal function of rats during treatment with stevioside. J Ethnopharmacol 1991;33:257-622. PubMed
  5. Hsieh MH, Chan P, Sue YM, et al. Efficacy and tolerability of oral stevioside in patients with mild essential hypertension: a two-year, randomized, placebo-controlled study. Clin Ther 2003;25:2797-808. PubMed
  6. Chan P, Tomlinson B, Chen YJ, et al. A double-blind placebo-controlled study of the effectiveness and tolerability of oral stevioside in human hypertension. Br J Clin Pharmacol 2000;50:215-20. PubMed
  7. Gregersen S, Jeppesen PB, Holst JJ, Hermansen K. Antihyperglycemic effects of stevioside in type 2 diabetic subjects. Metabolism 2004;53:73-6. PubMed
  8. Barriocanal LA, Palacios M, Benitez G, et al. Apparent lack of pharmacological effect of steviol glycosides used as sweeteners in humans. A pilot study of repeated exposures in some normotensive and hypotensive individuals and in Type 1 and Type 2 diabeti
  9. Ferri LA, Alves-Do-Prado W, Yamada SS, et al. Investigation of the antihypertensive effect of oral crude stevioside in patients with mild essential hypertension. Phytother Res 2006;20:732-6. PubMed
  10. Almiron-Roig E, Navas-Carretero S, Castelnuovo G, et al. Impact of acute consumption of beverages containing plant-based or alternative sweetener blends on postprandial appetite, food intake, metabolism, and gastro-intestinal symptoms: Results of the SWEE

See these in context on the Stevia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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