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Dietary supplement

Strontium Citrate 680 mg Ingredients & Drug Interactions

by NusaPure

Strontium Citrate 680 mg label
See full label image
Capsule Category: Mineral
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Strontium Citrate 680 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Strontium Citrate 680 mg is a dietary supplement by NusaPure with 1 active ingredient. Its ingredients are commonly taken for bone health and osteoporosis, reducing fracture risk, tooth sensitivity (in some toothpastes).Based on those ingredients, 101 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Strontium Citrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Strontium Citrate 680 mg by NusaPure

Ask about any prescription or over-the-counter medication and we check it for interactions with Strontium Citrate 680 mg by NusaPure — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Strontium Citrate 680 mg by NusaPure

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Strontium Citrate” is listed as a grouped ingredient — the label gives one combined amount (680 mg) without saying how much of each component you get.

This supplement contains one active ingredient: strontium, delivered as strontium citrate at 680 mg per capsule. The capsule itself is filled with inactive ingredients — cellulose, magnesium stearate, rice flour, and silica — which are binders and flow agents that help deliver the strontium.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Strontium's overall clinical evidence instead.

Strong

Strong clinical evidence supports Strontium for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Dental hypersensitivity — rated "Effective" (Natural Medicines).
  • On file: Painful bony metastases — rated "Effective" (Natural Medicines).
  • On file: Osteoporosis — rated "Likely Effective" (Natural Medicines).
  • On file: Osteoarthritis — rated "Possibly Effective" (Natural Medicines).
  • On file: Prostate cancer — rated "Possibly Effective" (Natural Medicines).

Strontium is effective for dental hypersensitivity and pain from bone metastases (cancer spread to bone). It's likely effective for osteoporosis — the evidence supports its use there.

For osteoarthritis and prostate cancer, the research shows it's possibly effective, meaning there's some promise but we need stronger evidence. Talk with your doctor about whether strontium makes sense for your specific condition.

The evidence, ingredient by ingredient Strontium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Strontium ranelate (the form used here) is generally well tolerated at doses up to 680 mg of elemental strontium daily, long-term. Common side effects are mild — atopic dermatitis (eczema-like skin irritation), diarrhea, headache, and nausea.

However, strontium has been linked to serious heart and clotting risks: clinical research shows it raises the risk of blood clots in the veins (venous thromboembolism) by about 50% and heart attack risk by about 1.6-fold in people with osteoporosis. Rare but serious side effects include heart attack, soft-bone disease (osteomalacia), and blood clots in the lungs.

During pregnancy, safety has not been established — it's best avoided. While breastfeeding, there isn't enough safety information, so avoid use.

Side effects, ingredient by ingredient Strontium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Strontium.
  • The most serious interaction on file is rated Moderate.
  • For scale: 101 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications if you take estrogens (birth control, hormone therapy), androgens (testosterone), antacids, quinolone antibiotics (ciprofloxacin, levofloxacin), or tetracycline antibiotics (doxycycline, tetracycline) — all have documented moderate interactions. Separate strontium by at least 2 hours from antacids and antibiotics; estrogens and androgens may increase strontium buildup in your body.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Strontium may help with bone pain, dental sensitivity, or osteoporosis, but it carries real cardiovascular and clotting risks that warrant a conversation with your doctor first. If you take estrogens, androgens, antacids, or antibiotics, you'll need to coordinate timing or skip the supplement.

Run your full medication list through our checker before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Strontium Citrate 680 mg, straight from the product label.

Brand NusaPure
Barcode (UPC) X001WM8CID
Net contents 200 Veg Cap(s)
Market status On market
Date entered into DSLD Apr 22, 2021
DSLD ID 247044
Product type Mineral
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Strontium Citrate 680 mg by NusaPure, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Veg Capsule(s)
Maximum serving Sizes:
2 Veg Capsule(s)
Servings per container
100
UPC/BARCODE
X001WM8CID
IngredientAmount% DV
Strontium231 mg--
Strontium Citrate680 mg--

Other ingredients: Cellulose, Magnesium Stearate, Rice Flour, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: For adults, take two (2) capsules daily, preferably with meals.

Precautions

Warning: If you are pregnant, nursing or taking any medications, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18. Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Allergen Information: Contains no artificial coloring, artificial flavor, preservatives, yeast, corn, milk or milk derivatives, lactose, salt, sodium, soy, sugar, gluten, starch or wheat. Produced in a GMP facility that processes other ingredients containing these allergens.

Storage

Store in cool dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Premium Quality Assembled in USA GMO Free Made with non-GMO Ingredients Gluten Free FDA Registered Facility

Manufactured in a cGMP Inspected Facility

Formulation

GMO Free Made with non-GMO Ingredients Gluten Free FDA Registered Facility

Assembled in USA Tested Supports healthy skeletal structure Supports collagen production Supports healthy bones & teeth Supports cellular health Max Strength

Allergen Information: Contains no artificial coloring, artificial flavor, preservatives, yeast, corn, milk or milk derivatives, lactose, salt, sodium, soy, sugar, gluten, starch or wheat.

Natural color variation may occur in this product.

Formula

Strontium citrate 680 mg per serving

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Strontium Citrate 680 mg by NusaPure label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Strontium Citrate 680 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Strontium Citrate 680 mg by NusaPure

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Veg Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Strontium Citrate

Interacts with
101 drugs
680 mg per serving

Strontium is a mineral that has been studied mainly for bone health and osteoporosis. The prescription form (strontium ranelate) showed benefit for fr...

Strontium Citrate monograph & interactions

Other (inactive) ingredients: Cellulose, Magnesium Stearate, Rice Flour, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Strontium Citrate 680 mg by NusaPure Drug Interactions

Want to check YOUR meds against Strontium Citrate 680 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
101Drugs
101 Moderate

Ingredients driving the most interactions

Strontium Citrate 101

Individual Drug Interactions

The ingredients in Strontium Citrate 680 mg interact with 101 drugs. Click any drug to see the details.

1 of the 1 ingredient in Strontium Citrate 680 mg interact with drugs. Each result below shows which ingredient is responsible. Strontium Citrate

Each ingredient & the kinds of drugs it affects

For each ingredient in Strontium Citrate 680 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Strontium Citrate5 drug types · 101 drugs

Androgens

Theoretically, androgens might reduce the excretion of strontium, potentially increasing its effects and adverse effects.
A small clinical study suggests that treatment with androgens such as testosterone, nandrolone, oxandrolone, and oxymetholone for 5-6 weeks might decrease urinary strontium excretion. The clinical significance of this interaction is unknown.

Likelihood Possible Evidence D
Antacids

Antacids can reduce the absorption of strontium, potentially decreasing its effectiveness.
Aluminum hydroxide and magnesium hydroxide can reduce absorption of strontium ranelate by 20% to 25%. Calcium can reduce its absorption to 60% to 70%. Avoid taking antacids within 2 hours of a dose of strontium ranelate. This interaction has also been reported with orally-administered radioactive strontium-85. It will likely also occur with other forms of strontium.

Likelihood Probable Evidence C
Estrogens

Theoretically, estrogens might reduce the excretion of strontium, potentially increasing its effects and adverse effects.
A small clinical study suggests that treatment with estrogens for 5-6 weeks might decrease urinary strontium excretion. The clinical significance of this interaction is unknown.

Likelihood Possible Evidence D
Quinolone Antibiotics

Theoretically, strontium might decrease the absorption of quinolone antibiotics.
Strontium is a divalent cation with similar properties to calcium. It is likely to form complexes with quinolones in the gastrointestinal (GI) tract, preventing absorption of the antibiotic. Recommend taking strontium supplements at least 2 hours before or after quinolones to avoid an interaction.

Likelihood Probable Evidence D
Tetracycline Antibiotics

Theoretically, strontium might decrease the absorption of tetracycline antibiotics.
Strontium is a divalent cation with similar properties to calcium. It is likely to form complexes with tetracyclines in the gastrointestinal (GI) tract, preventing absorption of the antibiotic. Recommend taking strontium supplements at least 2 hours before or after tetracyclines to avoid an interaction.

Likelihood Probable Evidence D
Strontium Citrate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Strontium Citrate 680 mg, from the product label.

NusaPure

See all NusaPure products
Name
Gmax Central LLC
Street Address
4700 Millenia Boulevard, Suite 175 PMB 92909
City
Orlando
State
FL
ZipCode
32839
Pharmacist Counseling Corner

Strontium Citrate 680 mg by NusaPure: Common Questions

Does Strontium Citrate 680 mg by NusaPure interact with any medications?
Yes. Based on its ingredients, Strontium Citrate 680 mg has a known interaction with 101 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Strontium Citrate 680 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is strontium used for?
Strontium is effective for dental hypersensitivity (sensitive teeth) and pain from bone tumors. It's likely effective for osteoporosis and possibly effective for osteoarthritis and prostate cancer. Your doctor can advise whether it's right for your condition.
What are the side effects?
Most people tolerate strontium at this dose well. Common mild side effects include skin irritation (atopic dermatitis), diarrhea, headache, and nausea. Rare but serious risks include blood clots in the legs or lungs, and heart attack — especially in people with osteoporosis. Discuss these risks with your doctor.
Can I take this while pregnant or breastfeeding?
Safety hasn't been established in pregnancy, so it's best avoided. There isn't enough safety data for breastfeeding either, so avoid use. Talk to your doctor or pharmacist if you're pregnant, planning to become pregnant, or breastfeeding.
Why can't I take this with antacids?
Antacids — especially those with calcium, aluminum, or magnesium — bind to strontium in your stomach and gut, blocking absorption and making the supplement less effective. Wait at least 2 hours between your antacid and this supplement.
Does this interact with antibiotics?
Yes. Quinolone antibiotics (like ciprofloxacin) and tetracycline antibiotics (like doxycycline) can't be absorbed well if strontium is present. Take your antibiotic at least 2 hours before or after this supplement to avoid reducing how much antibiotic gets into your bloodstream.
Does the dose in this capsule matter for interactions?
The 680 mg dose in this capsule is the standard elemental strontium dose used in clinical studies and is the amount known to be tolerated long-term. The interaction risks remain the same at this dose — spacing matters more than the amount itself.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Strontium Citrate 680 mg label
Go deeper

The Full Monographs Behind Strontium Citrate 680 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Strontium

Interacts with 101 drugs

Strontium is a mineral that has been studied mainly for bone health and osteoporosis. The prescription form (strontium ranelate) showed benefit for fracture risk but carries serious heart-re...

Read the full Strontium monograph →
Sources

Sources & How We Checked

Strontium Citrate 680 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 22 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Strontium 22 references
  1. Martindale W. Martindale the Extra Pharmacopoeia. Pharmaceutical Press, 1999.
  2. Meunier PJ, Roux C, Seeman E, et al. The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis. N Engl J Med 2004;350:459-68.. PubMed
  3. El-Hajj Fuleihan G. Strontium ranelate--a novel therapy for osteoporosis or a permutation of the same? N Engl J Med 2004;350:504-6. PubMed
  4. Verberckmoes SC, De Broe ME, D'Haese PC. Dose-dependent effects of strontium on osteoblast function and mineralization. Kidney Int 2003;64:534-43. . PubMed
  5. Meunier PJ, Slosman DO, Delmas PD, et al. Strontium ranelate: dose-dependent effects in established postmenopausal vertebral osteoporosis--a 2-year randomized placebo controlled trial. J Clin Endocrinol Metab 2002;87:2060-6.. DOI
  6. Brandi ML. New treatment strategies: ipriflavone, strontium, vitamin D metabolites and analogs. Am J Med 1993;95:69S-74S. . PubMed
  7. Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
  8. Metastron prescribing information. Medi-Physics, Inc., Amersham Healthcare, Arlington Heights, IL, 1998. http://www.cancerpaintherapy.com/METATECHPAGE.htm. (Accessed 13 March 2004).
  9. Protelos European Summary of Product Characteristics. Les Laboratoires Servier, 2006. Available at: www.servier.com/pro/osteoporose/protelos/protelos_spc.asp. (Accessed 01 August 2006).
  10. US Department of Health and Human Services, Public Health Service. Agency for Toxic Substances and Disease Registry. Toxicological profile for strontium. April 2004. Available at: www.atsdr.cdc.gov/toxprofiles/tp159.pdf. (Accessed 8 August 2006).
  11. Apostolidis N, Paradellis T, Karydas A, et al. Calcium and strontium metabolic studies in patients on CAPD. Perit Dial Int 1998;18:410-4. DOI
  12. Ozgur S, Sumer H, Kocoglu G. Rickets and soil strontium. Arch Dis Child 1996;75:524-6. PubMed
  13. Schrooten I, Elseviers MM, Lamberts LV, et al. Increased serum strontium levels in dialysis patients: an epidemiological survey. Kidney Int 1999;56:1886-92. PubMed
  14. D'Haese PC, Couttenye MM, Lamberts LV, et al. Aluminum, iron, lead, cadmium, copper, zinc, chromium, magnesium, strontium, and calcium content in bone of end-stage renal failure patients. Clin Chem 1999;45:1548-56. DOI
  15. Pennington JA, Jones JW. Molybdenum, nickel, cobalt, vanadium, and strontium in total diets. J Am Diet Assoc 1987;87:1644-50. DOI
  16. O'Donnell S, Cranney A, Wells GA, et al. Strontium ranelate for preventing and treating postmenopausal osteoporosis. Cochrane Musculoskeletal Group. Cochrane Database Syst Rev 2006;(4):CD005326. PubMed
  17. Protelos European Public Assessment Report, Scientific Discussion. European Medicines Agency, 2005. Available at: www.emea.eu.int/humandocs/Humans/EPAR/protelos/protelos.htm. (Accessed 10 October 2006).
  18. Rousselet F, El Solh N, Maurat JP, et al. Strontium and calcium metabolism. Interaction of strontium and vitamin D. C R Seances Soc Biol Fil 1975;169:322-9.
  19. O'Donnell, S., Cranney, A., Wells, G. A., Adachi, J. D., and Reginster, J. Y. Strontium ranelate for preventing and treating postmenopausal osteoporosis. Cochrane.Database.Syst.Rev. 2006;3:CD005326. PubMed
  20. Rizzoli R, Chapurlat RD, Laroche JM, et al. Effects of strontium ranelate and alendronate on bone microstructure in women with osteoporosis. Results of a 2-year study. Osteoporosis Int. 2012. 23(1):305-315. doi: 10.1007/s00198-011-1758-z. PubMed
  21. Reginster JY, Kaufman JM, Goemaere S, et al. Maintenance of antifracture efficacy over 10 years with strontium ranelate in postmenopausal osteoporosis. Osteoporos Int. 2012;23(3):1115-1122. doi: 10.1007/s00198-011-1847-z. PubMed
  22. Protos [Product Information]. Available at: http://www.guildlink.com.au/gc/ws/servier/pi.cfm?product=sepproto. Accessed May 1, 2018.

See these in context on the Strontium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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