Interactions on record — worth a quick check against your medications. Based on 5 of 7 ingredients. Check your meds →
Dietary supplement

Super Advanced NOS Blast Fruit Punch Ingredients & Drug Interactions

by Body Fortress

Powder Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Super Advanced NOS Blast Fruit Punch is a dietary supplement by Body Fortress with 7 active ingredients. Its ingredients are commonly taken for morning sickness in pregnancy, premenstrual syndrome (pms), preventing or treating b6 deficiency.Based on those ingredients, 250 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin B6, Taurine, Folic Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Super Advanced NOS Blast Fruit Punch by Body Fortress

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 7 of its 7 active ingredients.
  • “Folate” is listed as a grouped ingredient — the label gives one combined amount (700 mcg DFE) without saying how much of each component you get.
  • “Neuro-Max Blend” is a proprietary blend — the label gives one combined amount (1.15 Gram(s)) without saying how much of each component you get.

This powder contains 7 active ingredients. Vitamin B6, folic acid, and vitamin B12 are B-complex vitamins that support energy and nerve function.

Taurine is an amino acid that plays a role in heart and muscle function. Choline supports brain health and metabolism.

The product also includes a proprietary blend labeled "Folate" (a form of folic acid) and two other blended ingredients — Strength-ATP Matrix and Nitro-Dilate Complex — whose exact contents aren't detailed on the label. The remaining ingredients are fillers and sweeteners (maltodextrin, citric acid, flavoring, beet juice color, silica, and sucralose) that add texture and taste.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: energy, strength, and workout performance.
  • We looked for evidence on: Athletic performance, Attention, Cognitive function, Endurance, Power output, Pre-workout readiness.
  • The closest evidence on file: Choline is rated "Possibly Ineffective" for Athletic performance (Natural Medicines).
  • Also on file: Choline is rated "Insufficient Reliable Evidence To Rate" for Cognitive function.
  • Also on file: Vitamin B12 is rated "Insufficient Reliable Evidence To Rate" for Cognitive function, Attention.

The evidence for this product's ingredients varies. Vitamin B6 is effective for certain rare blood disorders and B6 deficiency itself, and it's possibly effective for pregnancy-related nausea.

Folic acid is effective for folate deficiency and likely effective at preventing neural tube birth defects and reducing methotrexate toxicity. Vitamin B12 is effective for B12 deficiency and certain rare conditions.

Taurine and choline show only limited evidence — taurine is possibly effective for liver disease and heart failure but possibly ineffective for weight loss; choline has insufficient evidence to rate for most uses it's promoted for. Because this is a pre-workout or athletic supplement, we hold no effectiveness data in our monographs for whether the blend as a whole improves exercise performance.

The evidence, ingredient by ingredient Vitamin B6 Vitamin B12 Choline Folic Acid Taurine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin B6 is generally well tolerated at normal doses but can cause nerve damage (sensory neuropathy) with high doses over time — especially above 1,000 mg daily or with cumulative exposure. Most people experience only mild side effects like headache or nausea.

Folic acid is generally safe at standard doses; at high doses it can rarely cause serious effects. Vitamin B12 is very safe with no established upper limit.

Taurine is generally well tolerated short-term in typical doses, though long-term safety is less certain, and rare serious effects have been reported in case reports involving energy drinks with multiple ingredients. Choline is safe in food amounts but at very high doses (above 3.5 grams daily) can cause a fishy body odor, nausea, and gastrointestinal upset.

All ingredients are rated safe or likely safe during pregnancy and breastfeeding at normal recommended amounts, though you should follow your healthcare provider's guidance on supplementation.

Side effects, ingredient by ingredient Vitamin B6 Vitamin B12 Choline Folic Acid Taurine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Choline, Vitamin B12, Vitamin B6, Folic Acid, Taurine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium; Parkinson's medications.
  • For scale: 250 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check these medication types before taking this product: blood pressure medications (Moderate risk from vitamin B6 and taurine), seizure drugs including phenobarbital, phenytoin, and primidone (Moderate risk from folic acid), methotrexate for cancer (Moderate risk from folic acid), cancer drugs capecitabine and 5-fluorouracil (Moderate risk from folic acid), heart rhythm medications like amiodarone (Moderate risk from vitamin B6), pyrimethamine for parasitic infections (Moderate risk from folic acid), lithium for mood disorders (Moderate risk from taurine), diabetes medication metformin (Minor risk from vitamin B12), and atropine (Minor risk from choline). We could not check two proprietary blends — Strength-ATP Matrix and Nitro-Dilate Complex.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is a multi-ingredient supplement with several nutrients that have real evidence behind them — especially the B vitamins for deficiency and birth-defect prevention. If you take any blood pressure medication, a heart rhythm drug, seizure medication, diabetes medication, cancer medication, or lithium, you need to check your specific drugs with the tool on this page before starting.

Talk to your pharmacist or doctor about whether this product makes sense for you and your medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Super Advanced NOS Blast Fruit Punch, straight from the product label.

Brand Body Fortress
Barcode (UPC) 074312765094
Net contents 1 lb(s); 16 Ounce(s); 454 Gram(s)
Market status On market
Date entered into DSLD Dec 13, 2022
DSLD ID 278495
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Super Advanced NOS Blast Fruit Punch by Body Fortress, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
13 Gram(s), 26 Gram(s)
Maximum serving Sizes:
13 Gram(s), 26 Gram(s)
Servings per container
17
UPC/BARCODE
074312765094
IngredientAmount% DV
Vitamin B624 mg, 48 mg1412%, 2824%
Folic Acid420 mcg, 840 mcg--
Vitamin B12140 mcg, 280 mcg5833%, 11667%
Taurine1 Gram(s)--
Choline150 mg, 300 mg27%, 55%
Folate700 mcg DFE, 1400 mcg DFE175%, 350%
Calories45 Calorie(s), 90 Calorie(s)--
Total Carbohydrate3 Gram(s), 5 Gram(s)1%, 2%
Total Sugars1 Gram(s), 1 Gram(s)--
added Sugars1 Gram(s), 1 Gram(s)1%, 2%
Strength-ATP Matrix8.3 Gram(s)--
Nitro-Dilate Complex2.25 Gram(s)--
Neuro-Max Blend1.15 Gram(s)--

Other ingredients: Maltodextrin, Citric Acid, Natural and Artificial flavors, Beet juice color, Silica, Sucralose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Servings per container about 35, about 17

Body Fortress knows that actions speak louder than words. That's why we don't waste your time with gimmicky pre-workout supplements promising unrealistic results. Super advanced NOS Blast contains powerful dosages of key ingredients designed to help deliver enhanced focus, increased strength, and explosive energy during your workout. There's no room for nonsense when you train with super advanced NOS Blast, because every workout deserves your best performance.

For more information on other Body Fortress products or for complete training and nutrition programs, visit www.bodyfortress.com.

New!

Contents are sold by weight. Some settling may occur.

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Formula

Caffeine to enhance energy & mental focus Creatine to maximize strength & power Strength ATP Matrix to improve recovery

Fruit Punch naturally and artificially flavored Creatine L-Arginine L-Citrulline Beta-Alanine

Please note: Crystalline Taurine will appear as small crystals within the powder.

Formulation

Contains zero aspartame - Zero gluten - Zero gimmicks

GF Gluten free

Pre-workout amplifier

Enhance energy & mental focus Maximize strength & power Increase reps during training

Free Of: Wheat, milk or milk derivatives, lactose, soy.

Suggested/Recommended/Usage/Directions

Use in conjunction with an intense daily exercise program and a balanced diet including an adequate caloric intake. Directions: For adults, mix one (1) to two (2) scoops with 10-12 fluid ounces of water and consume prior to your workout. Vary the amount of water to achieve your desired flavor and sweetness level. Take this product with an adequate daily fluid intake for hydration. As a reminder, discuss the supplements and medications you take with your health care providers. Begin with half the recommended dosage to assess individual tolerance and gradually increase to 2 scoops after several workouts. Do not take more than 2 scoops in a 24-hour period.

Precautions

Warning: Not intended for use by pregnant or nursing women. If you are taking any medications or have any medical condition, consult your doctor before use.

Avoid this product if you have kidney disease. Beta-alanine may cause a temporary tingling sensation, which is a normal reaction. Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18 or for those sensitive to caffeine.

Not intended for use by persons under the age of 18 or for those sensitive to caffeine.

Keep out of the reach of children.

For your protection, do not use if seal under cap is broken or missing.

This product contains caffeine. Avoid additional consumption of caffeine, which may cause adverse effects.

Storage

Store at room temperature, tightly closed and avoid excessive heat.

Brand IP Statement(s)

CarnoSyn Carnosine Synthesizer Natural Alternatives International (NAI) is the owner of the patents as listed on www.carnosyn.com and registered trademark of CarnoSyn.

Body Fortress Your body - Your fortress

Seals/Symbols

cGMP Manufactured Manufactured according to cGMP standards, as is required for all dietary supplements.

Made in the USA from select ingredients from around the world.

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Super Advanced NOS Blast Fruit Punch by Body Fortress label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Super Advanced NOS Blast Fruit Punch by Body Fortress

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size13 Gram(s) Dosage formPowder Servings per container17 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin B6

Interacts with
210 drugs
24 mg per serving Form: Pyridoxine Hydrochloride

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...

Vitamin B6 monograph & interactions

Vitamin B12

Interacts with
20 drugs
140 mcg per serving Form: Cyanocobalamin

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very h...

Vitamin B12 monograph & interactions

Choline

Interacts with
16 drugs
150 mg per serving Form: Choline Bitartrate

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like egg...

Choline monograph & interactions

Folate

700 mcg DFE per serving

Strength-ATP Matrix

8.3 Gram(s) per serving

Nitro-Dilate Complex

2.25 Gram(s) per serving

Neuro-Max Blend

1.15 Gram(s) per serving

Other (inactive) ingredients: Maltodextrin, Citric Acid, Natural and Artificial flavors, Beet juice color, Silica, Sucralose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Super Advanced NOS Blast Fruit Punch by Body Fortress Drug Interactions

Want to check YOUR meds against Super Advanced NOS Blast Fruit Punch?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
250Drugs
214 Moderate 36 Minor

Ingredients driving the most interactions

Taurine 173
Choline 16

Each ingredient & the kinds of drugs it affects

For each ingredient in Super Advanced NOS Blast Fruit Punch with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin B65 drug types · 210 drugs

Amiodarone (Cordarone)

Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Levodopa

Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.

Likelihood Unlikely Evidence D

Taurine2 drug types · 173 drugs

Antihypertensive Drugs

Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Some clinical evidence suggests that taurine can reduce both systolic and diastolic blood pressure.

Likelihood Probable Evidence D
Lithium

Theoretically, taurine might reduce excretion and increase plasma levels of lithium.
Taurine is thought to have diuretic properties, which might reduce the excretion of lithium.

Likelihood Probable Evidence D

Folic Acid7 drug types · 40 drugs

5-Fluorouracil

Theoretically, high doses of folic acid might increase the toxicity of 5-fluorouracil.
Increases in gastrointestinal side effects of 5-fluorouracil, such as stomatitis and diarrhea, have been described in two clinical studies when leucovorin, a form of folic acid, was administered with 5-fluorouracil.

Likelihood Possible Evidence D
Capecitabine (Xeloda)

Use of high-dose folic acid might contribute to capecitabine toxicity.
Clinical research suggests that higher serum folate levels are associated with an increased risk for moderate or severe toxicity during capecitabine-based treatment for colorectal cancer. Additionally, in one case report, taking folic acid 15 mg daily might have contributed to increased toxicity, including severe diarrhea, vomiting, edema, hand-foot syndrome, and eventually death, in a patient prescribed capecitabine.

Likelihood Possible Evidence D
Methotrexate (Trexall, Others)

Folic acid might reduce the efficacy of methotrexate as a cancer treatment when given concurrently.
Methotrexate exerts its cytotoxic effects by preventing conversion of folic acid to the active form needed by cells. There is some evidence that folic acid supplements reduce the efficacy of methotrexate in the treatment of acute lymphoblastic leukemia, and theoretically they could reduce its efficacy in the treatment of other cancers. Advise cancer patients to consult their oncologist before using folic acid supplements. In patients treated with long-term, low-dose methotrexate for rheumatoid arthritis (RA) or psoriasis, folic acid supplements can reduce the incidence of side effects, without reducing efficacy.

Likelihood Probable Evidence B
Phenobarbital (Luminal)

Folic acid might have antagonistic effects on phenobarbital and increase the risk for seizures.
Folic acid can have direct convulsant activity in some people, reversing the effects of phenobarbital and worsening seizure control. Monitor closely for increased seizure activity.

Likelihood Probable Evidence B
Phenytoin (Dilantin)

Folic acid might reduce serum levels of phenytoin in some patients.
Folic acid may be a cofactor in phenytoin metabolism. Folic acid, in doses of 1 mg daily or more, can reduce serum levels of phenytoin in some patients. Increases in seizure frequency have been reported. If folic acid supplements are added to established phenytoin therapy, monitor serum phenytoin levels closely. If phenytoin and folic acid are started at the same time and continued together, adverse changes in phenytoin pharmacokinetics are avoided. Note that phenytoin also reduces serum folate levels.

Likelihood Probable Evidence B
Primidone (Mysoline)

Folic acid might have antagonistic effects on primidone and increase the risk for seizures.
Folic acid can have direct convulsant activity in some people, reversing the effects of primidone and worsening seizure control. Monitor closely for increased seizure activity. Note that primidone also reduces serum folate levels.

Likelihood Probable Evidence B
Pyrimethamine (Daraprim)

Folic acid might antagonize the effects of pyrimethamine.
Folic acid can antagonize the antiparasitic effects of pyrimethamine against toxoplasmosis and Pneumocystis carinii pneumonia. Folic acid doesn't antagonize the effects of pyrimethamine in the treatment of malaria, because malarial parasites cannot use exogenous folic acid. Use folinic acid as an alternative to folic acid when indicated.

Likelihood Probable Evidence D

Vitamin B121 drug type · 20 drugs

Metformin (Glucophage)

Metformin, a common medication used to manage type 2 diabetes, has been associated with lower vitamin B12 levels in some individuals. Prolonged use of metformin can interfere with the absorption of B12 in the digestive system, potentially leading to a deficiency in this essential vitamin.

Likelihood Possible Evidence A

Choline1 drug type · 16 drugs

Atropine

Theoretically, choline might decrease the effects of atropine in the brain.
Animal research shows that administering choline one hour before administering atropine can attenuate atropine-induced decreases in brain levels of acetylcholine. Theoretically, concomitant use of choline and atropine may decrease the effects of atropine.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Super Advanced NOS Blast Fruit Punch, from the product label.

Body Fortress

See all Body Fortress products
Name
United States Nutrition, Inc.
City
Bohemia
State
NY
ZipCode
11716
Phone Number
1-800-215-5980
Web Address
www.bodyfortress.com
Pharmacist Counseling Corner

Super Advanced NOS Blast Fruit Punch by Body Fortress: Common Questions

Does Super Advanced NOS Blast Fruit Punch by Body Fortress interact with any medications?
Yes. Based on its ingredients, Super Advanced NOS Blast Fruit Punch has a known interaction with 250 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Super Advanced NOS Blast Fruit Punch contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant?
The B vitamins and choline in this product are rated safe or likely safe at normal doses during pregnancy — in fact, folic acid is recommended to prevent birth defects. However, because this is a supplement with multiple active ingredients and a pre-workout formula, it's best to talk with your obstetrician or midwife about whether it's right for your specific situation.
Is this safe to take every day?
The individual B vitamins, choline, and taurine are generally well tolerated for regular use at the doses typical in supplements. However, very high daily intakes of some ingredients (especially vitamin B6 and choline at doses well above what's in a single serving) can pose risks with long-term use. Stick to the label dose and talk to your pharmacist if you're combining this with other supplements or high-dose vitamin products.
What does taurine do in this product?
Taurine is an amino acid that plays a role in heart and muscle function. It's possibly effective for heart failure and liver disease, though the evidence is limited. It's also included in many pre-workout and athletic supplements, though we don't have evidence data on whether the ingredient as a whole improves exercise performance.
Will this help with my workout performance?
This product contains vitamins and amino acids involved in energy and muscle function, but we hold no effectiveness data on whether the supplement as a whole improves athletic performance. The individual ingredients have different evidence levels, so results may vary. Your training, nutrition, and rest matter most.
What are those blend ingredients — Strength-ATP Matrix and Nitro-Dilate Complex?
Those are proprietary blends, meaning the exact amounts of their component ingredients aren't disclosed on the label. We don't hold data on how to check them for interactions either. If you have questions about what's in them or how they work, contact the manufacturer directly.
Does this contain anything I should avoid if I have a sulfa allergy?
One ingredient to be aware of: taurine is a sulfur-containing compound, and there is a case report of an allergic reaction to taurine in someone with a history of sulfonamide and sulfite allergies. If you have these allergies, check with your pharmacist or doctor before taking this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Super Advanced NOS Blast Fruit Punch is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Super Advanced NOS Blast Fruit Punch label
Go deeper

The Full Monographs Behind Super Advanced NOS Blast Fruit Punch’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Super Advanced NOS Blast Fruit Punch's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 153 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin B6 32 references
  1. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Geerling BJ, Dagnelie PC, Badart-Smook A, et al. Diet as a risk factor for the development of ulcerative colitis. Am J Gastroenterol 2000;95:1008-13. PubMed
  4. South M. Neonatal seizures after pyridoxine use -- reply. Lancet 1999;354:2083. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  6. Baxter P, Aicardi J. Neonatal seizures after pyridoxine use. Lancet 1999;354:2082-3. PubMed
  7. Bendich A, Cohen M. Vitamin B6 safety issues. Ann N Y Acad Sci 1990;585:321-30.
  8. Schaumburg H, Kaplan J, Windebank A. Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome. N Engl J Med 1983;309:445-8. PubMed
  9. Gordon N. Pyridoxine dependency: an update. Dev Med Child Neurol 1997;39:63-5. PubMed
  10. Lewis PJ. Pain in the hand and wrist. Pyridoxine supplements may help patients with carpal tunnel syndrome. BMJ 1995;310:1534. PubMed
  11. Kaufman G. Pyridoxine against amiodarone-induced photosensitivity (letter). Lancet 1984;1:51-2. PubMed
  12. Mulrow JP, Mulrow CD, McKenna WJ. Pyridoxine and amiodarone-induced photosensitivity. Ann Intern Med 1985;103:68-9. PubMed
  13. Kawada A, Kashima A, Shiraishi H, et al. Pyridoxine-induced photosensitivity and hypophosphatasia. Dermatology 2000;201:356-60.. PubMed
  14. Vasile A, Goldberg R, Kornberg B. Pyridoxine toxicity: report of a case. J Am Osteopath Assoc 1984;83:790-1. DOI
  15. Hansson O, Sillanpaa M. Pyridoxine and serum concentration of phenytoin and phenobarbitone. Lancet 1976;1:256. DOI
  16. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  17. Chittumma P, Kaewkiattikun K, Wiriyasiriwach B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial. J Med Assoc Thai 2007;90:15-20.
  18. Hatzitolios, A., Iliadis, F., Katsiki, N., and Baltatzi, M. Is the anti-hypertensive effect of dietary supplements via aldehydes reduction evidence based? A systematic review. Clin Exp.Hypertens. 2008;30(7):628-639. PubMed
  19. Vasdev, S., Ford, C. A., Parai, S., Longerich, L., and Gadag, V. Dietary vitamin B6 supplementation attenuates hypertension in spontaneously hypertensive rats. Mol.Cell Biochem. 1999;200(1-2):155-162.
  20. de, Vogel S., Dindore, V., van, Engeland M., Goldbohm, R. A., van den Brandt, P. A., and Weijenberg, M. P. Dietary folate, methionine, riboflavin, and vitamin B-6 and risk of sporadic colorectal cancer. J Nutr 2008;138(12):2372-2378. PubMed
  21. Hagen, I., Nesheim, B. I., and Tuntland, T. No effect of vitamin B-6 against premenstrual tension. A controlled clinical study. Acta Obstet.Gynecol.Scand. 1985;64(8):667-670. PubMed
  22. Aybak, M., Sermet, A., Ayyildiz, M. O., and Karakilcik, A. Z. Effect of oral pyridoxine hydrochloride supplementation on arterial blood pressure in patients with essential hypertension. Arzneimittelforschung. 1995;45(12):1271-1273.
  23. Lal, K. J., Dakshinamurti, K., and Thliveris, J. The effect of vitamin B6 on the systolic blood pressure of rats in various animal models of hypertension. J Hypertens. 1996;14(3):355-363. PubMed
  24. Lauritzen CH, Reuter HD, Repges R, Bohnert K, and Schmidt U. Treatment of premenstrual tension syndrome with Vitex agnus castus. Controlled, double-blind study versus pyridoxine. Phytomed 1997;4(3):183-189. PubMed
  25. Fonseca VA, Lavery LA, Thethi TK, et al. Metanx in type 2 diabetes with peripheral neuropathy: A randomized trial. Am J Med 2013;126(2):141-9. PubMed
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Vitamin B12 30 references
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Taurine 21 references
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  12. Fujita, T., Ando, K., Noda, H., Ito, Y., and Sato, Y. Effects of increased adrenomedullary activity and taurine in young patients with borderline hypertension. Circulation 1987;75(3):525-532. PubMed
  13. Darling, P. B., Lepage, G., Leroy, C., Masson, P., and Roy, C. C. Effect of taurine supplements on fat absorption in cystic fibrosis. Pediatr Res 1985;19(6):578-582. PubMed
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  15. Franconi, F., Bennardini, F., Mattana, A., Miceli, M., Ciuti, M., Mian, M., Gironi, A., Anichini, R., and Seghieri, G. Plasma and platelet taurine are reduced in subjects with insulin-dependent diabetes mellitus: effects of taurine supplementation. Am.J. DOI
  16. Stohs SJ, Miller M. A case study involving allergic reactions to sulfur-containing compounds including, sulfite, taurine, acesulfame potassium and sulfonamides. Food Chem Toxicol. 2014 Jan;63:240-3. PubMed
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Choline 14 references
  1. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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