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Dietary supplement

SuperGlu Ingredients & Drug Interactions

by Syntrax

SuperGlu label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking SuperGlu against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

SuperGlu is a dietary supplement by Syntrax with 1 active ingredient. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against SuperGlu by Syntrax

Ask about any prescription or over-the-counter medication and we check it for interactions with SuperGlu by Syntrax — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of SuperGlu by Syntrax

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 17, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

SuperGlu is a single-ingredient powder containing L-glutamine, an amino acid your body uses for immune function, gut health, and muscle recovery. There are no inactive ingredients listed.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: glutamine supplementation for medical food use.
  • We looked for evidence on: HIV/AIDS-related wasting, Critical illness (trauma), Postoperative recovery, Wound healing, Oral mucositis, Chemotherapy-induced diarrhea — and 4 related terms.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for HIV/AIDS-related wasting (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Effective" for Critical illness (trauma), Postoperative recovery.
  • Also on file: Glutamine is rated "Possibly Ineffective" for Radiation-induced diarrhea.

The evidence supports L-glutamine for sickle cell disease, where it's rated effective. It's rated possibly effective for HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma — meaning there's some promise, but the evidence isn't yet as strong.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-glutamine is generally well tolerated by healthy adults. The most common side effects are gastrointestinal: belching, bloating, constipation, diarrhea, flatulence, nausea, vomiting, and abdominal pain.

Headache, musculoskeletal pain, cough, and dizziness have also been reported. A few cases of mood changes (mania or hypomania) occurred in people with bipolar disorder taking high doses.

If you have kidney or liver disease, use it only under medical supervision. There isn't enough safety data to recommend it during pregnancy unless your doctor advises it, though it's rated likely safe in pregnancy.

For breastfeeding, there's limited data, so avoid supplement doses unless a clinician recommends it.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take anticonvulsant medications (seizure medications), discuss this product with your doctor or pharmacist before starting it. The interaction is rated moderate and hasn't been observed in humans yet, but it's important to confirm it's safe for your specific situation.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

SuperGlu is an option if you're dealing with sickle cell disease or muscle recovery from surgery or critical illness, and your doctor agrees it's appropriate for you. If you take anticonvulsants, check with your doctor or pharmacist first — the interaction is theoretical but worth discussing.

People with kidney or liver disease should get medical supervision before starting it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about SuperGlu, straight from the product label.

Brand Syntrax
Barcode (UPC) 893912123567
Net contents 17.6 Oz(s); 1.1 lb; 500 Gram(s)
Market status On market
Date entered into DSLD Jun 25, 2015
DSLD ID 46209
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for SuperGlu by Syntrax, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 Gram(s)
Maximum serving Sizes:
10 Gram(s)
Servings per container
100
UPC/BARCODE
893912123567
IngredientAmount% DV
Calories20 {Calories}--
L-Glutamine5 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

To put it simply, it is perfect! Gone are the days of synthetic glutamine with its peculiar odors and strange tastes. Gone are the days of synthetic glutamine with its unknown and potentially harmful impurities. Gone are the days of gluatmine that doesn't disperse and suspend instantly in solution.

Fermented & Micronized

Fermented Maximum Purity! Micronized Maximum Results!

Brand IP Statement(s)

SuperGlu's(TM) superior manufacturing process guarantees a product that is snowy white without off-tastes and odors. Improving the quality even further, SuperGlu(TM) is micronized so that each and every serving is a pleasure to take. If you're using glutamine powder, make sure it's SuperGLu(TM).

SuperGLU(TM) is Syntrax's(R) 100% natural, ultra-pure, micronized glutamine powder. No other glutamine powder on the market matches the outstanding qualities of SuperGLU(TM)

Formula

SuperGlu(TM) is specifically formulated to be used as a medical food for patients with glutamine deficiency due to gastrointestinal disease, HIV/AIDS, cancer or severe infections or wounds.

Ultra-Pure Glutamine

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

SYNTRAX GUARANTEED QUALITY & PURITY EVERY TIME

100% Natural

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

RECOMMENDATIONS: Take 1-2 level scoops two to three times daily with meals or after exercise. Mix with water, juice or your favorite beverage for optimal convenience.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

SuperGlu by Syntrax label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

SuperGlu label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in SuperGlu by Syntrax

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size5 Gram(s) Dosage formPowder Servings per container100 Amounts shown are per serving.

L-Glutamine

Interacts with
50 drugs
5 Gram(s) per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions
Interaction report

SuperGlu by Syntrax Drug Interactions

Want to check YOUR meds against SuperGlu?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

L-Glutamine 50

Individual Drug Interactions

The ingredients in SuperGlu interact with 50 drugs. Click any drug to see the details.

1 of the 1 ingredient in SuperGlu interact with drugs. Each result below shows which ingredient is responsible. L-Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in SuperGlu with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for SuperGlu, from the product label.

Syntrax

See all Syntrax products
Name
SI03, Inc.
Street Address
PO Box 1715
City
Cape Girardeau
State
MO
ZipCode
63702
Phone Number
(866) 333-7403
Web Address
www.syntrax.com
Pharmacist Counseling Corner

SuperGlu by Syntrax: Common Questions

Does SuperGlu by Syntrax interact with any medications?
Yes. Based on its ingredients, SuperGlu has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
SuperGlu contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is L-glutamine and what does it do?
L-glutamine is an amino acid — one of the building blocks your body uses to make protein and support immune function and gut health. It's especially studied for muscle recovery after surgery or critical illness, and for managing wasting in HIV/AIDS.
What are the most common side effects?
Stomach and digestive issues are the most frequent: bloating, constipation, diarrhea, nausea, vomiting, and abdominal pain. Headache, belching, and flatulence also occur. These tend to happen at higher doses and often resolve if you reduce how much you take.
Is it safe during pregnancy?
L-glutamine is rated likely safe in pregnancy based on the data we hold. If you're pregnant or planning to become pregnant, talk with your doctor about whether this product is right for you.
Can I take it while breastfeeding?
There isn't enough safety information available for breastfeeding. Avoid supplement doses unless a clinician tells you it's okay — talk with your doctor or pharmacist about your specific situation.
Will this help with muscle recovery after surgery?
L-glutamine is rated possibly effective for postoperative recovery, meaning there's some evidence it may help, but more research is needed to be certain. Your doctor can discuss whether it's worth trying as part of your recovery plan.
Does it work for sickle cell disease?
Yes — L-glutamine is rated effective for sickle cell disease and has the strongest evidence of all its uses. If you have sickle cell disease, talk with your hematologist about whether this supplement is appropriate for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

SuperGlu label
Go deeper

The Full Monographs Behind SuperGlu’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph →
Sources

Sources & How We Checked

SuperGlu's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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