Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Thriphala Ingredients & Drug Interactions

by Bixa Botanical

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Thriphala is a dietary supplement by Bixa Botanical with 3 active ingredients. Its ingredients are commonly taken for antioxidant support, cholesterol and heart health, immune support.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Amla. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Thriphala by Bixa Botanical

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Triphala - Three Myrobalans extract” is listed as a grouped ingredient — the label gives one combined amount (450 mg) without saying how much of each component you get.

Triphala contains three active ingredients: amla (Indian gooseberry), bibhitaki, and haritaki. In Ayurvedic medicine, triphala is a traditional blend used to support digestive health.

Each ingredient plays a role in the traditional formula, though the scientific evidence for the combination as a whole is still developing. The capsule itself is made from HPMC, a plant-based capsule material.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Laxative and antioxidant support.
  • We looked for evidence on: Dyslipidemia, Hypercholesterolemia, Cardiovascular disease (CVD), Diabetes, Metabolic syndrome, Obesity — and 4 related terms.
  • The strongest evidence on file: Indian Gooseberry is rated "Possibly Effective" for Dyslipidemia (Natural Medicines).
  • Also on file: Indian Gooseberry is rated "Insufficient Reliable Evidence To Rate" for Aging skin, Cardiovascular disease (CVD), Diabetes, Hypercholesterolemia, and more.

Amla is rated possibly effective for acid reflux (GERD) and for high cholesterol (dyslipidemia). The evidence for amla in treating hair loss (androgenic alopecia) and for lowering overall cholesterol levels is insufficient — we don't have enough reliable data to rate it one way or the other.

We don't hold effectiveness ratings for the other two active ingredients in this blend.

The evidence, ingredient by ingredient Indian Gooseberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Amla is generally well tolerated when used as a food, but safety data for supplement doses is less studied. During breastfeeding, there isn't enough reliable safety information, so you should avoid it while nursing unless your doctor advises otherwise.

In clinical trials, a small number of people reported mild side effects: stomach discomfort or indigestion, fatigue, and musculoskeletal pain — none were reported by more than a handful of participants.

Side effects, ingredient by ingredient Indian Gooseberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Indian Gooseberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check if you're on blood thinners or antiplatelet drugs (warfarin, dabigatran, apixaban, aspirin, clopidogrel, and others) — amla may increase bleeding risk. Also check any diabetes medications you take, since amla can lower blood sugar and raise the risk of low blood sugar episodes.

If you take any of these, run them through the medication checker below.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you're interested in traditional digestive or cholesterol support and don't take blood thinners or diabetes medications, this could be worth trying with your pharmacist's nod. If you're pregnant, nursing, or taking any anticoagulants, antiplatelets, or diabetes drugs, talk to your pharmacist or doctor first — the interaction potential is real.

Check your exact medications on this page before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Thriphala, straight from the product label.

Brand Bixa Botanical
Barcode (UPC) X001C67N4N
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jun 24, 2020
DSLD ID 228921
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Women (not pregnant or lactating), Halal
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Thriphala by Bixa Botanical, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
X001C67N4N
IngredientAmount% DV
Amla0 NP--
Bibhitaki0 NP--
Haritaki0 NP--
Triphala - Three Myrobalans extract450 mg--

Other ingredients: HPMC Vegetarian Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Warning: This product is not intended for use by those with serious medical condition or pregnant or lactating women. Consult your physician before use.

Keep out of reach of children.

Do not use if seal is broken.

FDA Disclaimer Statement

Disclaimer: These statements have not been evaluated by the Food and Drug Administration and this product is a food supplement and not intended to diagnose treat or cure or prevent any disease.

Seals/Symbols

Halal Mumbai India Halal Committee Registration No. 0854 K LBD (Kosher) Good manufacturing practices GMP

Formulation

Vegan

Laxative & anti-oxidant

Formula

K LBD (Kosher)

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: 1 capsules 2 times daily after food or as directed by physician

Storage

Store in a cool and dry place.

General Statements

Neutral code: MP/25D/9/89

See for yourself

Thriphala by Bixa Botanical label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Thriphala by Bixa Botanical

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Triphala - Three Myrobalans extract

450 mg per serving Form: Tannins
  • Amla
  • › Bibhitaki
  • › Haritaki

Other (inactive) ingredients: HPMC Vegetarian Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Thriphala by Bixa Botanical Drug Interactions

Want to check YOUR meds against Thriphala?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Amla 208

Each ingredient & the kinds of drugs it affects

For each ingredient in Thriphala with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Amla4 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, Indian gooseberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking Indian gooseberry 500 mg along with clopidogrel 75 mg or ecosprin 75 mg, as a single dose or for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with clopidogrel 75 mg or ecosprin 75 mg alone. Until more is known, use caution when taking Indian gooseberry in combination with anticoagulant/antiplatelet drugs.

Likelihood Possible Evidence B
Antidiabetes Drugs

Taking Indian gooseberry with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking Indian gooseberry fruit or fruit extract alone or in conjunction with antidiabetes medications can lower blood glucose levels. Dose adjustments to diabetes medications might be necessary.

Likelihood Possible Evidence B
Aspirin

Theoretically, Indian gooseberry may increase the risk of bleeding if used with aspirin; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking a single dose of Indian gooseberry 500 mg along with ecosprin 75 mg, or taking a combination of Indian gooseberry 500 mg twice daily plus ecosprin 75 mg once daily for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with ecosprin 75 mg alone.

Likelihood Possible Evidence B
Clopidogrel (Plavix)

Theoretically, Indian gooseberry may increase the risk of bleeding if used with clopidogrel; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking a single dose of Indian gooseberry 500 mg along with clopidogrel 75 mg, or taking a combination of Indian gooseberry 500 mg twice daily plus clopidogrel 75 mg once daily for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with clopidogrel 75 mg alone.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for Thriphala, from the product label.

Bixa Botanical

See all Bixa Botanical products
Name
Jairamdass Khushiram
Street Address
Plot No - M -14/14-1, MIDC, Taloja
City
410 208 Maharasthra
Phone Number
00-91-22-2783 1232
Web Address
www.bixabotanical.com
Pharmacist Counseling Corner

Thriphala by Bixa Botanical: Common Questions

Does Thriphala by Bixa Botanical interact with any medications?
Yes. Based on its ingredients, Thriphala has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Thriphala contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this work for acid reflux?
The amla in this formula is rated possibly effective for acid reflux (GERD), which means there's some evidence it may help, but we need more research to be sure. Whether triphala as a whole blend works is less established in the data we hold.
Can I take this while pregnant?
There isn't enough safety data for amla at supplement doses during pregnancy to say it's safe. Talk with your doctor or pharmacist — they can weigh your individual situation and give you personalized advice.
Can I take this if I'm breastfeeding?
There's too little reliable safety information for amla during breastfeeding, so it's best to avoid it. Chat with your pharmacist or doctor if you're considering it.
What are the side effects?
In clinical trials, a few people reported stomach discomfort or indigestion, fatigue, and muscle or joint pain — but these were uncommon. Amla is generally well tolerated.
What is amla and why is it in this product?
Amla is Indian gooseberry, a fruit used in Ayurvedic medicine. It's one of three ingredients in the traditional triphala blend, which has been used to support digestive and overall health for centuries.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Thriphala label
Sources

Sources & How We Checked

Thriphala's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Indian Gooseberry 6 references
  1. Sabu, M. C. and Kuttan, R. Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol. 2002;81(2):155-160. PubMed
  2. Fatima N, Pingali U, Muralidhar N. Study of pharmacodynamic interaction of Phyllanthus emblica extract with clopidogrel and ecosprin in patients with type II diabetes mellitus. Phytomedicine. 2014;21(5):579-85. PubMed
  3. Shanmugarajan D, Girish C, Harivenkatesh N, Chanaveerappa B, Prasanna Lakshmi NC. Antihypertensive and pleiotropic effects of Phyllanthus emblica extract as an add-on therapy in patients with essential hypertension-A randomized double-blind placebo-contro
  4. Akhtar MS, Ramzan A, Ali A, Ahmad M. Effect of amla fruit (Emblica officinalis Gaertn.) on blood glucose and lipid profile of normal subjects and type 2 diabetic patients. Int J Food Sci Nutr. 2011;62(6):609-16.
  5. Usharani P, Fatima N, Muralidhar N. Effects of Phyllanthus emblica extract on endothelial dysfunction and biomarkers of oxidative stress in patients with type 2 diabetes mellitus: a randomized, double-blind, controlled study. Diabetes Metab Syndr Obes. 20 PubMed
  6. Majeed M, Mundkur L, Paulose S, Nagabhushanam K. Novel Emblica officinalis extract containing ß-glucogallin vs. metformin: a randomized, open-label, comparative efficacy study in newly diagnosed type 2 diabetes mellitus patients with dyslipidemia. Food Fu

See these in context on the Indian Gooseberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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