TMJ-Ease Ingredients & Drug Interactions
What is this page for?
First and foremost: checking TMJ-Ease against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
TMJ-Ease is a dietary supplement by Earth Friend Herb Co. with 8 active ingredients. Its ingredients are commonly taken for urinary tract complaints, mild bladder irritation, increasing urine flow (diuretic).Based on those ingredients, 311 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sheep Sorrel, Elderberry, Irish Moss. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against TMJ-Ease by Earth Friend Herb Co.
Ask about any prescription or over-the-counter medication and we check it for interactions with TMJ-Ease by Earth Friend Herb Co. — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of TMJ-Ease by Earth Friend Herb Co.
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
TMJ-Ease contains eight active herbal ingredients: couch grass, Irish moss, elderberry, lobelia, Iceland moss, white pond lily, sheep sorrel, and condurango. The product is a liquid form and also contains two inactive ingredients, alcohol and glycerin, which serve as a base and preservative.
Each herb is included for its traditional use in herbal formulas.
Does it work?
Couldn't assess
The evidence base for most of these ingredients is limited. Elderberry has been studied for hay fever, heart disease, chronic fatigue, COPD, memory, and respiratory infections, but the data don't support a reliable rating for any of these uses.
Lobelia is rated possibly ineffective for smoking cessation. White pond lily, sheep sorrel, and condurango all lack sufficient evidence for the conditions they're traditionally used for — these include back pain, burns, cough, wound healing, bronchitis, breast cancer, and others.
There's no established evidence in our data for the other ingredients either.
How safe is it?
Well-documented data
Several ingredients are generally well tolerated in the short term, though human safety data are limited across the board. Lobelia carries the strongest caution: it can be toxic at higher doses and cause nausea, vomiting, diarrhea, dizziness, tremors, and throat irritation at doses as low as 50 mg; at 600 mg or higher, it may cause serious effects including rapid heartbeat, dangerously low blood pressure, and even death.
Elderberry products made from cooked ripe fruit are generally well tolerated, but raw or unripe berries and seeds contain toxins that can cause nausea, vomiting, severe diarrhea, weakness, dizziness, and other effects. Sheep sorrel is safe in food amounts but medicinal doses haven't been proven safe; it's high in oxalates, which can stress the kidneys.
Iceland moss may cause stomach irritation and can be contaminated with lead. White pond lily is used mostly on skin and carries limited safety data.
Meds to double-check
Moderate interaction found
Before taking TMJ-Ease, check with your pharmacist if you're on lithium (a mood stabilizer), immunosuppressant drugs, pazopanib (a cancer medication), blood thinners or antiplatelet drugs like aspirin or warfarin, or fexofenadine (Allegra). These are the medication types documented to interact with ingredients in this product at moderate severity.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This herbal liquid is aimed at TMJ support, but the evidence backing most ingredients isn't established in our data. If you take lithium, immunosuppressants, pazopanib, blood thinners, or antihistamines like fexofenadine, you need to check your exact medications with us before starting.
The lobelia content also warrants caution given its toxicity risk at higher doses. Talk with your pharmacist or doctor before adding this to your routine.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 8 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about TMJ-Ease, straight from the product label.
| Brand | Earth Friend Herb Co. |
|---|---|
| Net contents | 4 Fluid Ounce(s); 120 mL |
| Market status | On market |
| Date entered into DSLD | Mar 25, 2025 |
| DSLD ID | 323664 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for TMJ-Ease by Earth Friend Herb Co., sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Couch Grass | 0 NP | -- |
| Irish Moss | 0 NP | -- |
| Elderberry | 0 NP | -- |
| Lobelia | 0 NP | -- |
| Iceland Moss | 0 NP | -- |
| White Pond Lily | 0 NP | -- |
| Sheep Sorrel | 0 NP | -- |
| Condurango | 0 NP | -- |
Other ingredients: Alcohol, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: Use 10-15 drops 3x daily. Take straight-then drink water.
Precautions
Keep away from children.
Not for use with pregnancy or nursing.
General Statements
An Elijah Free formula
Formulation
All certified organic or wild crafted herbs.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
TMJ-Ease by Earth Friend Herb Co. label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in TMJ-Ease by Earth Friend Herb Co.
These are the 8 active ingredients this product is made of. Select any to open its full monograph.
Serving size10 Drop(s) Dosage formLiquid Servings per container160 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Couch Grass
No knowninteractions
Couch grass is a common lawn weed whose rhizome has long been used in traditional European herbal medicine, mainly for urinary and bladder complaints....
Couch Grass monograph & interactionsIrish Moss
Interacts with22 drugs
Sea moss is a type of red seaweed that is naturally rich in iodine and several minerals, and it is popular as a 'whole-food' supplement. Strong human...
Irish Moss monograph & interactionsElderberry
Interacts with121 drugs
Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu sym...
Elderberry monograph & interactionsLobelia
Interacts with1 drug
Lobelia is a traditional herb once used for breathing problems and to help people quit smoking, but reliable evidence supporting these uses is lacking...
Lobelia monograph & interactionsIceland Moss
No knowninteractions
Iceland moss is a lichen traditionally used as a soothing remedy for dry cough and throat or mouth irritation, mainly because of its mucilage (gel-for...
Iceland Moss monograph & interactionsWhite Pond Lily
No knowninteractions
White Lily (Lilium candidum) is a flowering plant used mostly in traditional skin care, where its bulb- or flower-infused oils are applied for minor s...
White Pond Lily monograph & interactionsSheep Sorrel
Interacts with169 drugs
Sorrel is a tangy, leafy herb used in cooking and traditional medicine, often for congestion, digestion, and inflammation. Solid human evidence for an...
Sheep Sorrel monograph & interactionsCondurango
No knowninteractions
Condurango is the bark of a South American vine traditionally used as a bitter to stimulate appetite and ease digestive complaints. Modern scientific...
Condurango monograph & interactionsOther (inactive) ingredients: Alcohol, Glycerin. These complete the product’s ingredient list but are not active constituents.
TMJ-Ease by Earth Friend Herb Co. Drug Interactions
HelloPharmacist Interaction Report
TMJ-Ease by Earth Friend Herb Co. does interact with certain medications.
The most serious concern involves lobelia, one of its eight ingredients, which may interact with lithium (used for bipolar disorder). Lobelia's diuretic properties could theoretically reduce how your body clears lithium, potentially raising its level to unsafe amounts — your lithium dose might need adjustment if you're taking this product.
Read the full breakdown — every affected drug type, severity by severity
Elderberry in the formula has moderate interactions with immunosuppressant medications (drugs that calm your immune system, often used after transplants or for autoimmune diseases) and with pazopanib, a cancer medication. Elderberry stimulates immune activity, which could interfere with immunosuppressants' effects, and one case report linked elderberry to severe liver injury in a patient on pazopanib.
Sheep sorrel presents moderate interactions with blood thinners and antiplatelet drugs (like aspirin or warfarin), potentially adding to their blood-thinning effects. It may also reduce how well your body absorbs fexofenadine (Allegra, an antihistamine) and similar drugs that rely on a specific transport system in your gut.
Altogether, these interactions span 285 individual medications. We could not check Irish Moss — we hold no data for it.
Please run your specific medications through the checker below before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against TMJ-Ease?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in TMJ-Ease interact with 311 drugs. Click any drug to see the details.
4 of the 8 ingredients in TMJ-Ease interact with drugs. Each result below shows which ingredient is responsible. Sheep Sorrel Elderberry Irish Moss Lobelia
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
ElderberryImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry + 6-mercaptopurine interactionAbciximabReoPro
How Abciximab interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
Sheep SorrelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Sheep Sorrel + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with TMJ-Ease — through 2 ingredients. Tap an ingredient for the detail:
ElderberryImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry + Abrocitinib interactionSheep SorrelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Sheep Sorrel + Abrocitinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
Sheep SorrelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Sheep Sorrel + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
Sheep SorrelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Sheep Sorrel + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
Sheep SorrelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Sheep Sorrel + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
Sheep SorrelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Sheep Sorrel + Acetaminophen, Ibuprofen interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
Sheep SorrelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Sheep Sorrel + Acetylsalicylic Acid interactionAdalimumabHumira
How Adalimumab interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
ElderberryImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
ElderberryImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
ElderberryImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
ElderberryImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
ElderberryImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
ElderberryImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
ElderberryImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry + Adalimumab-fkjp interactionAlefaceptAmevive
How Alefacept interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
ElderberryImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
ElderberryImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry + Alemtuzumab interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
Sheep SorrelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Sheep Sorrel + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
Sheep SorrelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Sheep Sorrel + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
Sheep SorrelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Sheep Sorrel + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmiodaroneCordarone, Pacerone
How Amiodarone interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
Irish MossAmiodarone (cordarone) Moderate
Interaction Summary
Theoretically, combining sea moss with amiodarone might cause excessively high iodine levels.
Read the full Irish Moss + Amiodarone interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
Sheep SorrelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Sheep Sorrel + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
Sheep SorrelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Sheep Sorrel + Anagrelide interactionAnifrolumab-fniaSaphnelo
How Anifrolumab-fnia interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
ElderberryImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry + Anifrolumab-fnia interactionAnisindioneMiradon
How Anisindione interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
Sheep SorrelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Sheep Sorrel + Anisindione interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
Sheep SorrelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Sheep Sorrel + Antithrombin Iii interactionAntithymocyte GlobulinThymoglobulin
How Antithymocyte Globulin interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
ElderberryImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry + Antithymocyte Globulin interactionApixabanEliquis
How Apixaban interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
Sheep SorrelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Sheep Sorrel + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
Sheep SorrelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Sheep Sorrel + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with TMJ-Ease — through 1 ingredient. Tap an ingredient for the detail:
Sheep SorrelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Sheep Sorrel + Aspirin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in TMJ-Ease with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Sheep Sorrel
Anticoagulant/Antiplatelet Drugs
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
In vitro, sorrel has been shown to inhibit platelet aggregation. However, this effect has not been reported in humans.
Fexofenadine (Allegra)
Sorrel might reduce the effectiveness of fexofenadine by reducing its absorption from the gut.
In vitro research shows that an ethanol extract of sorrel inhibits organic anion-transporting polypeptide 1A2 (OATP1A2), which transports fexofenadine from the intestine into cells. In rats, concomitant administration of sorrel extract with fexofenadine reduces oral absorption of fexofenadine and the area under the plasma concentration-time curve (AUC).
Organic Anion-Transporting Polypeptide Substrates (Oatp)
Sorrel might reduce the effectiveness of OATP substrates by reducing their absorption from the gut.
In vitro research shows that sorrel inhibits OATP1A2. Theoretically it may inhibit other OATPs. The OATPs are expressed in the small intestine and liver and transport drugs into cells. Inhibition of OATP may reduce the bioavailability of oral drugs that are substrates of OATP.
Elderberry
Immunosuppressants
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Elderberry has immunostimulant activity, increasing the production of cytokines, including interleukin and tumor necrosis factor.
Pazopanib (Votrient)
Theoretically, elderberry might interact with pazopanib, potentially increasing the risk of adverse effects.
Irish Moss
Amiodarone (Cordarone)
Theoretically, combining sea moss with amiodarone might cause excessively high iodine levels.
Amiodarone contains 37.3% iodine and can increase iodine levels. Concomitant use with sea moss, which contains approximately 4-7 mcg of iodine per gram, might increase the risk of adverse effects from iodine, including altered thyroid function.
Antithyroid Drugs
Due to its iodine content, sea moss might alter the effects of antithyroid drugs.
Sea moss contains approximately 4-7 mcg of iodine per gram. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking sea moss could theoretically alter the effects of antithyroid drugs.
Thyroid Hormone
Due to its iodine content, sea moss might alter the effects of thyroid hormone.
Sea moss contains approximately 4-7 mcg of iodine per gram. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking sea moss could theoretically alter the effects of thyroid hormone.
Lobelia
Lithium
Lobelia is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, lobelia might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
Brand information
Manufacturer and brand details for TMJ-Ease, from the product label.
Earth Friend Herb Co.
See all Earth Friend Herb Co. products- Name
- Exsula Foods Inc.
- Street Address
- PO Box 44459
- City
- Tacoma
- State
- WA
- ZipCode
- 98448
- Phone Number
- 253-874-9092
- Web Address
- www.exsula.com
TMJ-Ease by Earth Friend Herb Co.: Common Questions
Does TMJ-Ease by Earth Friend Herb Co. interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is this safe to use while pregnant?
What about breastfeeding?
What's lobelia, and why the warning?
Does this actually work for TMJ problems?
Why can't you check Irish Moss for interactions?
What are the inactive ingredients?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if TMJ-Ease is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind TMJ-Ease’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Couch Grass
Couch grass is a common lawn weed whose rhizome has long been used in traditional European herbal medicine, mainly for urinary and bladder complaints. High-quality human studies are lacking,...
Read the full Couch Grass monograph → Herb & supplement monographSea Moss
Interacts with 22 drugsSea moss is a type of red seaweed that is naturally rich in iodine and several minerals, and it is popular as a 'whole-food' supplement. Strong human evidence for most of its health claims i...
Read the full Sea Moss monograph → Herb & supplement monographElderberry
Interacts with 121 drugsElderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu symptoms, but the evidence is limited and n...
Read the full Elderberry monograph → Herb & supplement monographLobelia
Interacts with 1 drugLobelia is a traditional herb once used for breathing problems and to help people quit smoking, but reliable evidence supporting these uses is lacking. It can be toxic in higher amounts, cau...
Read the full Lobelia monograph → Herb & supplement monographIceland Moss
Iceland moss is a lichen traditionally used as a soothing remedy for dry cough and throat or mouth irritation, mainly because of its mucilage (gel-forming fibers). High-quality human studies...
Read the full Iceland Moss monograph → Herb & supplement monographWhite Lily
White Lily (Lilium candidum) is a flowering plant used mostly in traditional skin care, where its bulb- or flower-infused oils are applied for minor skin problems and soothing. Good-quality...
Read the full White Lily monograph → Herb & supplement monographSorrel
Interacts with 169 drugsSorrel is a tangy, leafy herb used in cooking and traditional medicine, often for congestion, digestion, and inflammation. Solid human evidence for any health benefit is limited, and its hig...
Read the full Sorrel monograph → Herb & supplement monographCondurango
Condurango is the bark of a South American vine traditionally used as a bitter to stimulate appetite and ease digestive complaints. Modern scientific evidence supporting any of these uses is...
Read the full Condurango monograph →Sources & How We Checked
TMJ-Ease's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 29 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Sea Moss 3 references
- Darias-Rosales J, Rubio C, Gutiérrez ÁJ, Paz S, Hardisson A. Risk assessment of iodine intake from the consumption of red seaweeds (Palmaria palmata and Chondrus crispus). Environ Sci Pollut Res Int 2020;27(36):45737-45741. PubMed
- U.S. Department of Agriculture (USDA). Agricultural Research Service. FoodData Central. Seaweed, irishmoss, raw. April 2019. Available at: https://fdc.nal.usda.gov/fdc-app.html#/food-details/168456/nutrients. Accessed Aug. 30, 2022.
- Palmieri B, Vadalà M, Laurino C. Clinical effects of overwintered-stressed Chondrus Crispus and non-overwintered-stressed Chondrus crispus dietary supplementations. Asian J Med Sci. 2018; 9(6): 7-13. DOI
Elderberry 6 references
- Barak V, Halperin T, Kalickman I. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. Eur Cytokine Netw 2001;12:290-6..
- Elderberry (Sambucus species). The Poison Plant Patch, Novia Scotia Museum, 2007. Available at: http://museum.gov.ns.ca/poison/?section=species&id=117 (Accessed 16 October 2009).
- European elder. Canadian Poisonous Plants Information System. Available at: http://www.cbif.gc.ca/pls/pp/ppack.jump?p_null=all&p_psn=121&p_type=all&p_sci=comm&p_x=px (Accessed 16 October 2009).
- Raus K, Pleschka S, Klein P, Schoop R, Fisher P. Effect of an echinacea-based hot drink versus oseltamivir in Influenza treatment: a randomized, double-blind, double-dummy, multicenter, noninferiority clinical trial. . Curr Ther Res Clin Exp. 2015;20;77:6 PubMed
- Ramachandran A, Antala D, Pudasainee P, Panginikkod S, Gupta H. A Plausible Association Between the Use of Elderberry and Autoimmune Hepatitis. Cureus 2022;14(4):e24250. PubMed
- Agarwal N, Mangla A. Elderberry interaction with pazopanib in a patient with soft-tissue sarcoma: A case report and literature review. Mol Clin Oncol 2024;20(5):36. PubMed
Lobelia 6 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- McChargue DE, Collins FL Jr, Cohen LM. Effect of non-nicotinic moist snuff replacement and lobeline on withdrawal symptoms during 48-h smokeless tobacco deprivation. Nicotine Tob Res 2002;4:195-200. PubMed
- Stead LF, Hughes JR. Lobeline for smoking cessation. Cochrane Database Syst Rev 2000;2:CD000124. PubMed
- Plakun, A. L., Ambrus, J., Bross, I., Graham, S., Levin, M. L., and Ross, C. A. Clinical factors in smoking withdrawal: preliminary report. Am J Public Health Nations.Health 1966;56(3):434-441. PubMed
Iceland Moss 3 references
- Tyler VE. Herbs of Choice. Binghamton, NY: Pharmaceutical Products Press, 1994.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
White Lily 2 references
Sorrel 8 references
- Neubauer N, Marz RW. Placebo-controlled, randomized, double-blind, clincal trial with Sinupret sugar coated tablets on the basis of a therapy with antibiotics and decongestant nasal drops in acute sinusitis. Phytomedicine 1994;1:177-81.
- Marz RW, Ismail C, Popp MA. Action profile and efficacy of a herbal combination preparation for the treatment of sinusitis. Wien Med Wochenschr 1999;149:202-8.
- Zick, S. M., Sen, A., Feng, Y., Green, J., Olatunde, S., and Boon, H. Trial of Essiac to ascertain its effect in women with breast cancer (TEA-BC). J Altern Complement Med 2006;12(10):971-980. PubMed
- Sanz, P. and Reig, R. Clinical and pathological findings in fatal plant oxalosis. A review. Am J Forensic Med Pathol. 1992;13(4):342-345. PubMed
- Gniazdowska, B., Doroszewska, G., and Doroszewski, W. [Hypersensitivity to weed pollen allergens in the region of Bygdoszcz]. Pneumonol.Alergol.Pol. 1993;61(7-8):367-372.
- Selçuk SN, Gülhan B, Düzova A, Teksam Ö. Acute tubulointerstitial nephritis due to large amount of sorrel (Rumex acetosa) intake. Clin Toxicol (Phila) 2015;53(5):497. PubMed
- Ahn JH, Kim J, Rehman NU, Kim HJ, Ahn MJ, Chung HJ. Effect of Rumex Acetosa Extract, a Herbal Drug, on the Absorption of Fexofenadine. Pharmaceutics. 2020;12(6):E547. PubMed
- Jeong D, Irfan M, Lee DH, Hong SB, Oh JW, Rhee MH. Rumex acetosa modulates platelet function and inhibits thrombus formation in rats. BMC Complement Med Ther. 2020;20(1):98. PubMed
Condurango 1 reference
- Herbs at a Glance — NIH NCCIH Source
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