UBQH 50 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking UBQH 50 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
UBQH 50 mg is a dietary supplement by Integrative Therapeutics with 1 active ingredient. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are reduced form Coenzyme Q10. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against UBQH 50 mg by Integrative Therapeutics
Ask about any prescription or over-the-counter medication and we check it for interactions with UBQH 50 mg by Integrative Therapeutics — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of UBQH 50 mg by Integrative Therapeutics
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
UBQH 50 mg is a softgel capsule containing one active ingredient: reduced form coenzyme Q10 (CoQ10), a compound your cells use to produce energy and protect themselves from oxidative damage. The softgel is made with canola oil, gelatin, glycerol monooleate, glycerin, beeswax, purified water, sunflower lecithin, and caramel color—all inactive ingredients that help deliver the CoQ10.
Does it work?
Strong evidence
CoQ10 is likely effective for replacing coenzyme Q10 deficiency. The evidence supports its use as possibly effective for fibromyalgia, migraine headache, congestive heart failure (CHF), and diabetic nerve damage (neuropathy).
For other uses, the research in our data doesn't establish effectiveness.
How safe is it?
Well-documented data
CoQ10 is generally well tolerated by most adults when used as directed. The most common side effects are gastrointestinal—appetite suppression, diarrhea, stomach discomfort, heartburn, nausea, and vomiting—though these occur in less than 1% of people and can often be minimized by splitting doses above 100 mg throughout the day.
Headache, dizziness, insomnia, and skin itching have been reported rarely. There is not enough reliable safety data in pregnancy, so it's best to avoid it unless your doctor advises otherwise.
Safety while breastfeeding has not been well studied—talk with your doctor or pharmacist before using it if you're nursing.
Meds to double-check
Moderate interaction found
Before taking UBQH, check with your doctor or pharmacist if you take chemotherapy agents (especially alkylating agents like cyclophosphamide)—CoQ10 may reduce their effectiveness. If you take warfarin (Coumadin) for blood clotting, CoQ10 could decrease how well it works.
Blood pressure medications are another category to confirm, since CoQ10 might lower your blood pressure further. Use the medication search tool on this page to check your specific drugs.
The bottom line
Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
CoQ10 is a good option if you have CoQ10 deficiency or want to explore it for migraines, heart failure, fibromyalgia, or nerve pain—but you'll need to check it against your medications first, especially if you take chemotherapy drugs, warfarin, or blood pressure medicine. Because it can interfere with several important drug classes, talk with your own doctor or pharmacist before starting it.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about UBQH 50 mg, straight from the product label.
| Brand | Integrative Therapeutics |
|---|---|
| Barcode (UPC) | 871791000285 |
| Net contents | 60 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Jun 24, 2020 |
| DSLD ID | 222917 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for UBQH 50 mg by Integrative Therapeutics, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 5 Calorie(s) | -- |
| reduced form Coenzyme Q10 | 50 mg | -- |
Other ingredients: Canola Oil, Gelatin, Glycerol Monooleate, Glycerin, Beeswax, purified Water, Sunflower Lecithin, Caramel color
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions
Keep out of reach of children.
Safety sealed with printed inner seal. Do not use if seal is broken or missing.
If you are pregnant, nursing, or taking prescription drugs, consult your healthcare professional prior to use.
Seals/Symbols
Made with Quality Q+ Kaneka Ubiquinol
Brand IP Statement(s)
Q+, Kaneka Ubiquinol and the quality seal are registered or pending trademarks of Kaneka Corp.
2019 Distributed by Integrative Therapeutics, LLC
Formulation
Contains no salt, wheat, gluten, dairy products, or artificial flavors.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formula
Patented, stabilized, reduced Ubiquinol
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Recommendation: Take 1 softgel twice daily, or as recommended by your healthcare professional.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
UBQH 50 mg by Integrative Therapeutics label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in UBQH 50 mg by Integrative Therapeutics
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.
Reduced form Coenzyme Q10
Interacts with198 drugs
CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...
Reduced form Coenzyme Q10 monograph & interactionsOther (inactive) ingredients: Canola Oil, Gelatin, Glycerol Monooleate, Glycerin, Beeswax, Purified Water, Sunflower Lecithin, Caramel color. These complete the product’s ingredient list but are not active constituents.
UBQH 50 mg by Integrative Therapeutics Drug Interactions
HelloPharmacist Interaction Report
UBQH 50 mg by Integrative Therapeutics contains coenzyme Q10 (CoQ10), which has documented interactions with chemotherapy drugs, blood thinners, and blood pressure medications.
The most serious concern is with chemotherapy agents: CoQ10's antioxidant effects may theoretically reduce how well alkylating chemotherapy drugs (like cyclophosphamide) work by protecting tumor cells from the oxidative stress these drugs rely on to kill cancer cells.
Read the full breakdown — every affected drug type, severity by severity
CoQ10 can also interfere with warfarin (Coumadin), a blood thinner. Because CoQ10 is chemically similar to vitamin K, it may decrease warfarin's ability to prevent clotting—four cases of reduced warfarin effectiveness have been reported.
Blood pressure medications are a third concern: some research shows CoQ10 can lower blood pressure, so taking it alongside antihypertensive drugs could add up to too much of a drop.
Altogether, these interactions span 198 individual medications. If you take any cancer drugs, warfarin, or blood pressure medication, check your exact drugs with the tool on this page before starting CoQ10.
Your doctor or pharmacist can help you decide if it's safe to combine.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against UBQH 50 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in UBQH 50 mg interact with 198 drugs. Click any drug to see the details.
1 of the 1 ingredient in UBQH 50 mg interact with drugs. Each result below shows which ingredient is responsible. reduced form Coenzyme Q10
AltretamineHexalen
How Altretamine interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Reduced Form Coenzyme Q10 + Altretamine interactionBendamustineBelrapzo, Treanda, Vivimusta
How Bendamustine interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Reduced Form Coenzyme Q10 + Bendamustine interactionBendamustine HydrochlorideBendeka
How Bendamustine Hydrochloride interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Reduced Form Coenzyme Q10 + Bendamustine Hydrochloride interactionBusulfanBusulfex, Myleran
How Busulfan interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Reduced Form Coenzyme Q10 + Busulfan interactionCarboplatinParaplatin
How Carboplatin interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Reduced Form Coenzyme Q10 + Carboplatin interactionCarmustineBiCNU, Gliadel, Gliadel Wafer
How Carmustine interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Reduced Form Coenzyme Q10 + Carmustine interactionChlorambucilLeukeran
How Chlorambucil interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Reduced Form Coenzyme Q10 + Chlorambucil interactionCisplatinPlatinol-AQ
How Cisplatin interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Reduced Form Coenzyme Q10 + Cisplatin interactionCyclophosphamideCytoxan, Neosar
How Cyclophosphamide interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Reduced Form Coenzyme Q10 + Cyclophosphamide interactionDacarbazineDTIC-Dome
How Dacarbazine interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Reduced Form Coenzyme Q10 + Dacarbazine interactionEstramustine Phosphate SodiumEmcyt
How Estramustine Phosphate Sodium interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Reduced Form Coenzyme Q10 + Estramustine Phosphate Sodium interactionIfosfamideIfex
How Ifosfamide interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Reduced Form Coenzyme Q10 + Ifosfamide interactionLomustineCeenu
How Lomustine interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Reduced Form Coenzyme Q10 + Lomustine interactionLurbinectedinZepzelca
How Lurbinectedin interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Reduced Form Coenzyme Q10 + Lurbinectedin interactionMechlorethamine HydrochlorideValchlor
How Mechlorethamine Hydrochloride interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Reduced Form Coenzyme Q10 + Mechlorethamine Hydrochloride interactionMelphalanAlkeran, Hepzato
How Melphalan interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Reduced Form Coenzyme Q10 + Melphalan interactionMelphalan FlufenamidePepaxto
How Melphalan Flufenamide interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Reduced Form Coenzyme Q10 + Melphalan Flufenamide interactionMelphalan HydrochlorideEvomela
How Melphalan Hydrochloride interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Reduced Form Coenzyme Q10 + Melphalan Hydrochloride interactionOxaliplatinEloxatin
How Oxaliplatin interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Reduced Form Coenzyme Q10 + Oxaliplatin interactionProcarbazineMatulane
How Procarbazine interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Reduced Form Coenzyme Q10 + Procarbazine interactionStreptozocinZanosar
How Streptozocin interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Reduced Form Coenzyme Q10 + Streptozocin interactionTemozolomideTemodar
How Temozolomide interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Reduced Form Coenzyme Q10 + Temozolomide interactionThiotepaTepadina, Thioplex
How Thiotepa interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Reduced Form Coenzyme Q10 + Thiotepa interactionTrabectedinYondelis
How Trabectedin interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Reduced Form Coenzyme Q10 + Trabectedin interactionWarfarinWarfarin
How Warfarin interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Warfarin (coumadin) Moderate
Interaction Summary
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Read the full Reduced Form Coenzyme Q10 + Warfarin interactionWarfarin SodiumCoumadin, Panwarfin, Sofarin
How Warfarin Sodium interacts with UBQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Reduced Form Coenzyme Q10Warfarin (coumadin) Moderate
Interaction Summary
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Read the full Reduced Form Coenzyme Q10 + Warfarin Sodium interactionEach ingredient & the kinds of drugs it affects
For each ingredient in UBQH 50 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
reduced form Coenzyme Q10
Alkylating Agents
Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.
Warfarin (Coumadin)
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.
Antihypertensive Drugs
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.
Brand information
Manufacturer and brand details for UBQH 50 mg, from the product label.
Integrative Therapeutics
See all Integrative Therapeutics products- Name
- Integrative Therapeutics, LLC
- City
- Green Bay
- State
- WI
- ZipCode
- 54311
- Phone Number
- 800.931.1709
- Web Address
- integrativepro.com
UBQH 50 mg by Integrative Therapeutics: Common Questions
Does UBQH 50 mg by Integrative Therapeutics interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is the 'reduced form' of CoQ10, and why does it matter?
Can I take CoQ10 if I'm on a blood thinner like warfarin?
What are the most common side effects?
Is CoQ10 safe during pregnancy?
Can I take this if I'm undergoing chemotherapy?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if UBQH 50 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind UBQH 50 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
UBQH 50 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Coenzyme Q10 40 references
- Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
- Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
- Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
- Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
- Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
- Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
- Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
- Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
- Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
- Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
- Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
- The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
- Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
- Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
- Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
- Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
- Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
- Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
- Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
- Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
- Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
- Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
- Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
- Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
- Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
- Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
- Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
- Young, J. M., Florkowski, C. M., Molyneux, S. L., McEwan, R. G., Frampton, C. M., Nicholls, M. G., Scott, R. S., and George, P. M. A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the me
- Ishiyama, T., Morita, Y., Toyama, S., Yamagami, T., and Tsukamoto, N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn.Heart J 1976;17(1):32-42. PubMed
- Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A., Karpati, G., Andermann, F., and Arnold, D. L. Coenzyme Q10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease. Neurology 1993;43(5
- Malm, C., Svensson, M., Sjoberg, B., Ekblom, B., and Sjodin, B. Supplementation with ubiquinone-10 causes cellular damage during intense exercise. Acta Physiol Scand. 1996;157(4):511-512. PubMed
- Singh, R. B., Wander, G. S., Rastogi, A., Shukla, P. K., Mittal, A., Sharma, J. P., Mehrotra, S. K., Kapoor, R., and Chopra, R. K. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc. PubMed
- Digiesi V, Cantini F, and Brodbeck B. Effect of coenzyme Q10 on essential arterial hypertension. Current Therapeutic Research 1990;47(5):841-845.
- Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.
- Alehagen U, Johansson P, Bjornstedt M, et al. Cardiovascular mortality and N-terminal-proBNP reduced after combined selenium and coenzyme Q10 supplementation: A 5-year prospective randomized double-blind placebo-controlled trial among elderly Swedish citi
- Ho MJ, Li EC, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension. Cochrane Database Syst Rev. 2016 Mar 3;3:CD007435. doi: 10.1002/14651858.CD007435.pub3. PubMed
- Tabrizi R, Akbari M, Sharifi N, Lankarani KB, Moosazadeh M, Kolahdooz F, et al. The effects of coenzyme Q10 supplementation on blood pressures among patients with metabolic diseases: a systematic review and meta-analysis of randomized controlled trials. PubMed
- Tsai IC, Hsu CW, Chang CH, Tseng PT, Chang KV. Effectiveness of coenzyme Q10 supplementation for reducing fatigue: A systematic review and meta-analysis of randomized controlled trials. Front Pharmacol 2022;13:883251. PubMed
- Yaghini O, Hoseini N, Ghazavi MR, et al. A comparative study on the efficacy of coenzyme Q10 and amitriptyline in the prophylactic treatment of migraine headaches in children: A randomized controlled trial. Adv Biomed Res 2022;11:43. PubMed
- Hansen KS, Mogensen TH, Agergaard J, et al. High-dose coenzyme Q10 therapy versus placebo in patients with post COVID-19 condition: A randomized, phase 2, crossover trial. Lancet Reg Health Eur 2022. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC