Interactions on record — worth a quick check against your medications. Based on 3 of 7 ingredients. Check your meds →
Dietary supplement

Ultimate Flora Kids Probiotic 3 Billion Berry-Licious Ingredients & Drug Interactions

by Renew Life

Ultimate Flora Kids Probiotic 3 Billion Berry-Licious label
See full label image
Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Ultimate Flora Kids Probiotic 3 Billion Berry-Licious against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Ultimate Flora Kids Probiotic 3 Billion Berry-Licious is a dietary supplement by Renew Life with 7 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus acidophilus, Bacillus coagulans, Bifidobacterium breve. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Ultimate Flora Kids Probiotic 3 Billion Berry-Licious by Renew Life

Ask about any prescription or over-the-counter medication and we check it for interactions with Ultimate Flora Kids Probiotic 3 Billion Berry-Licious by Renew Life — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Ultimate Flora Kids Probiotic 3 Billion Berry-Licious by Renew Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 7 active ingredients.
  • “Kids Probiotic Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

This product contains 7 active ingredients, all of them live probiotic bacteria: Lactobacillus salivarius, Lactobacillus acidophilus, Bifidobacterium animalis lactis, Lactobacillus plantarum, Bacillus coagulans, and Bifidobacterium breve, plus a Kids Probiotic Blend and a measure of Total Probiotic Cultures. These are "good" bacteria meant to support digestive and immune health in children.

The inactive ingredients are xylitol, stearate, natural flavors, citric acid, vegetable stearate, and silica — standard tablet excipients that help hold the formula together and make it taste good.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: digestive balance and immune system support.
  • We looked for evidence on: Antibiotic-associated diarrhea, Colic, Constipation, Diarrhea, Flatulence, Irritable bowel syndrome (IBS) — and 4 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Irritable bowel syndrome (IBS).
  • Also on file: Bacillus Coagulans is rated "Possibly Effective" for Constipation, Irritable bowel syndrome (IBS).

The evidence behind these strains is mixed. Lactobacillus acidophilus is possibly effective for irritable bowel syndrome (IBS), Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis, though it's rated possibly ineffective for atopic disease and there isn't enough reliable evidence yet for acute respiratory distress syndrome.

Bacillus coagulans is possibly effective for constipation and IBS, but we don't have enough evidence to rate it for antibiotic-associated diarrhea, athletic performance, cancer, or fatty liver disease. Bifidobacterium breve is rated possibly ineffective for age-related cognitive decline and sepsis, with insufficient evidence for hay fever, antibiotic-associated diarrhea, and atopic disease.

For the other three strains in the product, we don't hold effectiveness ratings in our data.

The evidence, ingredient by ingredient Lactobacillus Acidophilus Bacillus Coagulans Bifidobacterium Breve

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus is generally well tolerated in healthy adults and children. Bacillus coagulans and Bifidobacterium breve are also generally well tolerated in healthy people, but both come with a caution: evidence and safety data are limited, so talk to your doctor before using, especially if your child is very ill or has a weakened immune system.

Gastrointestinal side effects like abdominal discomfort, bloating, flatulence, and diarrhea have been reported with probiotic use, though they're uncommon. In very rare cases, live probiotic bacteria have caused serious infections (like bacteremia or sepsis) in critically ill or immunocompromised patients, including preterm infants — but this risk is extremely low in healthy children.

There's no pregnancy or lactation safety data on file for these ingredients.

Side effects, ingredient by ingredient Lactobacillus Acidophilus Bacillus Coagulans Bifidobacterium Breve

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Lactobacillus Acidophilus, Bacillus Coagulans, Bifidobacterium Breve.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist if your child is taking antibiotic drugs (Moderate interaction). The three probiotic strains we could check — Lactobacillus acidophilus, Bacillus coagulans, and Bifidobacterium breve — may lose effectiveness if taken at the same time as antibiotics.

Spacing them out by a few hours usually solves this. For the three strains we couldn't check, no interactions are documented in our data, though that's not a guarantee none exist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This probiotic is designed for kids and is generally well tolerated in healthy children. If your child is taking an antibiotic, space out this supplement and the antibiotic by a few hours — ask your pharmacist for the exact timing.

If your child has a weakened immune system or is seriously ill, check with your doctor first. Run any medications or health concerns through your pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Ultimate Flora Kids Probiotic 3 Billion Berry-Licious, straight from the product label.

Brand Renew Life
Barcode (UPC) 631257158680
Net contents 30 Yummy Chewable Tablet(s)
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 243655
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Gluten Free, Dairy Free, Sugar Free, Children more than 1 but less than 4
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Ultimate Flora Kids Probiotic 3 Billion Berry-Licious by Renew Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Chew Tab(s)
Maximum serving Sizes:
1 Chew Tab(s)
Servings per container
30
UPC/BARCODE
631257158680
IngredientAmount% DV
Lactobacillus salivarius0 NP--
Lactobacillus acidophilus0 NP--
Bifidobacterium animalis lactis0 NP--
Lactobacillus plantarum0 NP--
Bacillus coagulans0 NP--
Bifidobacterium breve0 NP--
Kids Probiotic Blend0 NP--
Total Probiotic Cultures0 NP--

Other ingredients: Xylitol, Stearate, Natural Flavors, natural Fruit flavors, Citric Acid, Vegetable Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Free of wheat, gluten, soy, dairy, eggs, shellfish, tree nuts, and artificial ingredients. Made in a facility that handles wheat, gluten, soy, and dairy. Individuals extremely sensitive to these ingredients should consult a physician prior to using this product.

Helps promote digestive balance Supports the immune system Quality and purity guaranteed

Manufactured in USA

No artificial sweeteners, flavors, or colors Dairy, gluten, and sugar free

Manufactured in a GMP facility

Manufactured in USA

No sugar or artificial sweeteners

No artificial flavors, colors or preservatives Dairy, soy and gluten free

Helps promote digestive balance and support the immune system

Precautions

Keep out of reach of children.

Warning: Consult your physician before using this or any product if your child is taking medication or has a medical condition.

Warning: Consult your physician before using this or any product if your child is taking medication or has a medical condition.

Tamper Evident: Do not use if safety seal is broken or missing.

Tamper Evident: Do not use if safety seal on bottle is broken or missing.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

Formula

3 billion live cultures per tablet

Great berry-licious taste

Formulated to provide 3 billion live cultures per tablet at time of consumption, if prior to expiration, under recommended storage conditions. Storage and handling conditions may vary, and may affect the total amount of cultures delivered at consumption.

Better health begins in your kids digestive system Ultimate Flora Kids Probiotic is a safe and gentle way to help replenish the balance of "good" bacteria in the intestines to support a growing child's immune system.

Berri Bifido Licious Lacto

Important Notes Great natural berry-licious taste

Naturally sweetened with tooth-friendly xylitol

What are probiotics? Probiotics are the trillions of beneficial bacteria that naturally live in the intestines. Ultimate Flora Kids Probiotic includes two important types of kid-freindly bacteria, lacto (lactobacilli) and bifido (bifidobacteria). Why give kids probiotics? Every day your child is exposed to challenges to their immune and digestive systems while in school, at play or from the environment. Beneficial bacteria can be depleted by diets too high in sugar or too low in fiber, and by certain medications Digestion Probiotics, or "good bacteria," can promote a healthy balance of flora to support digestion. Probiotics are considered a safe and gentle way to help support the immune system. Defense

General Statements

Renew Life The digestive care experts

65444

Did you know? Up to 80% of the immune system is found in the intestines! Probiotics also produce vitamins and support regular, balanced digestion. Tastes Great!

FDA Statement of Identity

Probiotic Supplement

Suggested/Recommended/Usage/Directions

Directions: Chew 1 tablet daily with a light meal. Use only for children 2 years and older.

Storage

Store in a dry place at 73 degrees F (23 degrees C) or below. Refrigerate after opening.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Ultimate Flora Kids Probiotic 3 Billion Berry-Licious by Renew Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Ultimate Flora Kids Probiotic 3 Billion Berry-Licious label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Ultimate Flora Kids Probiotic 3 Billion Berry-Licious by Renew Life

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Chew Tab(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Kids Probiotic Blend

0 NP per serving

Other (inactive) ingredients: Xylitol, Stearate, Natural Flavors, Natural Fruit flavors, Citric Acid, Vegetable Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Ultimate Flora Kids Probiotic 3 Billion Berry-Licious by Renew Life Drug Interactions

Want to check YOUR meds against Ultimate Flora Kids Probiotic 3 Billion Berry-Licious?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Lactobacillus acidophilus 182
Bacillus coagulans 182
Bifidobacterium breve 182

Individual Drug Interactions

The ingredients in Ultimate Flora Kids Probiotic 3 Billion Berry-Licious interact with 182 drugs. Click any drug to see the details.

3 of the 7 ingredients in Ultimate Flora Kids Probiotic 3 Billion Berry-Licious interact with drugs. Each result below shows which ingredient is responsible. Lactobacillus acidophilus Bacillus coagulans Bifidobacterium breve

Each ingredient & the kinds of drugs it affects

For each ingredient in Ultimate Flora Kids Probiotic 3 Billion Berry-Licious with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillus acidophilus1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus acidophilus full monograph & interactions

Bacillus coagulans1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B. coagulans.
B. coagulans preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. coagulans preparations by at least two hours.

Likelihood Probable Evidence D
Bacillus coagulans full monograph & interactions

Bifidobacterium breve1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B. breve.
Since B. breve preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. breve preparations by at least 2 hours.

Likelihood Probable Evidence D
Bifidobacterium breve full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Ultimate Flora Kids Probiotic 3 Billion Berry-Licious, from the product label.

Renew Life

Name
Renew Life Formulas
City
Palm Harbor
State
FL
ZipCode
34683
Phone Number
1-800-830-1800
Web Address
www.renewlife.com
Pharmacist Counseling Corner

Ultimate Flora Kids Probiotic 3 Billion Berry-Licious by Renew Life: Common Questions

Does Ultimate Flora Kids Probiotic 3 Billion Berry-Licious by Renew Life interact with any medications?
Yes. Based on its ingredients, Ultimate Flora Kids Probiotic 3 Billion Berry-Licious has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Ultimate Flora Kids Probiotic 3 Billion Berry-Licious contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I give this to my child while they're on an antibiotic?
Yes, but timing matters. The antibiotic can kill the live bacteria in the probiotic if you give them at the exact same time. Ask your pharmacist how many hours to space them apart — usually 2 to 3 hours is enough. This way your child gets the benefit of both the antibiotic and the probiotic.
What are the main bacteria in this product supposed to do?
They're meant to support healthy digestion and immune function in kids. Lactobacillus acidophilus has the most evidence behind it for conditions like irritable bowel syndrome, diarrhea from antibiotics, and some infections, though it's possibly effective rather than proven. The other strains may help with constipation and overall gut health, but the evidence is less clear.
Are there any common side effects?
Most kids tolerate it well. A small number may experience bloating, gas, or loose stool when they first start — these are usually mild and temporary. Serious side effects are very rare and happen mostly in kids who are very sick or have weakened immune systems.
Does this have any artificial colors or sweeteners?
It's sweetened with xylitol, which is a natural sugar alcohol, and flavored with natural fruit flavors. There are no artificial colors listed. If your child has a sensitivity to any of the inactive ingredients, check the full list on the label.
How many strains of bacteria are in here?
There are seven active ingredients in total, including six named probiotic strains — Lactobacillus salivarius, Lactobacillus acidophilus, Bifidobacterium animalis lactis, Lactobacillus plantarum, Bacillus coagulans, and Bifidobacterium breve — plus a Kids Probiotic Blend and a measure of Total Probiotic Cultures.
Should I talk to my pediatrician before giving it?
It's generally safe for healthy kids, but yes — mention it to your pediatrician, especially if your child is on any medications or has a health condition that weakens their immune system. That way they can make sure it's the right choice for your child.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Ultimate Flora Kids Probiotic 3 Billion Berry-Licious is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Ultimate Flora Kids Probiotic 3 Billion Berry-Licious label
Go deeper

The Full Monographs Behind Ultimate Flora Kids Probiotic 3 Billion Berry-Licious’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph → Herb & supplement monograph

Bacillus Coagulans

Interacts with 182 drugs

Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, and certain types of diarrhea. The eviden...

Read the full Bacillus Coagulans monograph → Herb & supplement monograph

Bifidobacterium Breve

Interacts with 182 drugs

Bifidobacterium breve is a 'friendly' gut bacterium taken as a probiotic, most often to support digestion and balance the gut microbiome. Some studies suggest possible benefits for certain d...

Read the full Bifidobacterium Breve monograph →
Sources

Sources & How We Checked

Ultimate Flora Kids Probiotic 3 Billion Berry-Licious's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 44 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Bacillus Coagulans 20 references
  1. Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. PubMed
  2. Tynkkynen S, Singh KV, Varmanen P. Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 1998;41:195-204. PubMed
  3. Klein G, Zill E, Schindler R, et al. Peritonitis associated with vancomycin-resistant Lactobacillus rhamnosus in a continuous ambulatory peritoneal dialysis patient; organism identification, antibiotic therapy, and case report. J Clin Microbiol 1998;36:
  4. Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. PubMed
  5. Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. DOI
  6. Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60.
  7. MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed
  8. Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005;115:178-81.
  9. De Groote MA, Frank DN, Dowell E, et al. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatr Infect Dis J 2005;24:278-80. PubMed
  10. Vahabnezhad E, Mochon AB, Wozniak LJ, Ziring DA. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. J Clin Gastroenterol. 2013;47(5):437-9. PubMed
  11. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  12. Sendil S, Shrimanker I, Mansoora Q, Goldman J, Nookala VK. Lactobacillus rhamnosus bacteremia in an immunocompromised renal transplant patient. Cureus. 2020;12(2):e6887. PubMed
  13. Albarillo FS, Shah U, Joyce C, Slade D. Lactobacillus rhamnosus Infection: A single-center 4-year descriptive analysis. J Glob Infect Dis. 2020;12(3):119-123. PubMed
  14. Pasala S, Singer L, Arshad T, Roach K. Lactobacillus endocarditis in a healthy patient with probiotic use. IDCases. 2020;22:e00915. PubMed
  15. Agrawal S, Tuchman ES, Bruce MJ, Theodorou ME. Fatal Lactobacillus endocarditis in a patient with transcatheter aortic valve replacement. BMJ Case Rep. 2020;13(11):e236835.
  16. Antoun M, Hattab Y, Akhrass FA, Hamilton LD. Uncommon pathogen, Lactobacillus, causing infective endocarditis: Case report and review. Case Rep Infect Dis. 2020;2020:8833948. PubMed
  17. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  18. Franko B, Vaillant M, Recule C, Vautrin E, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics. Med Mal Infect. 2013;43(4):171-3. PubMed
  19. Campbell RE, Miller A, Afroze A. Native valve endocarditis secondary to Lactobacillus paracasei bacteremia. Consultant. 2020;60(9):27-8. DOI
  20. Kato K, Funabashi N, Takaoka H, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics with advanced and severe bicuspid aortic valve stenosis complicated with diffuse left ventricular mid-layer fibrosis. Int J Cardiol. 2016;224:157-161. PubMed

See these in context on the Bacillus Coagulans monograph →

Bifidobacterium Breve 9 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  3. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  4. Ohishi A, Takahashi S, Ito Y, et al. Bifidobacterium septicemia associated with postoperative probiotic therapy in a neonate with omphalocele. J Pediatr. 2010;156(4):679-81. PubMed
  5. Sakurai Y, Watanabe T, Miura Y, et al. Clinical and bacteriologic characteristics of six cases of Bifidobacterium breve bacteremia due to probiotic administration in the neonatal intensive care unit. Pediatr Infect Dis J 2022;41(1):62-65. PubMed
  6. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
  7. Wakabayashi Y, Nakayama S, Yamamoto A, et al. First case of necrotizing fasciitis and bacteremia caused by Bifidobacteriumbreve. Anaerobe 2022;76:102613.
  8. Takeda Y, Ota K, Kondo A, et al. A case of necrotizing fasciitis caused by Bifidobacterium breve. IDCases 2022;31:e01667. PubMed
  9. Suwantarat N, Romagnoli M, Wakefield T, Carroll KC. Ventriculoperitoneal shunt infection caused by Bifidobacterium breve. Anaerobe 2014;28:1-3. PubMed

See these in context on the Bifidobacterium Breve monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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