Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Ultimate Omega + CoQ10 Lemon Ingredients & Drug Interactions

by Nordic Naturals

Ultimate Omega + CoQ10 Lemon label
See full label image
Softgel Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Ultimate Omega + CoQ10 Lemon against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Ultimate Omega + CoQ10 Lemon is a dietary supplement by Nordic Naturals with 3 active ingredients. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Coenzyme Q-10. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Ultimate Omega + CoQ10 Lemon by Nordic Naturals

Ask about any prescription or over-the-counter medication and we check it for interactions with Ultimate Omega + CoQ10 Lemon by Nordic Naturals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Ultimate Omega + CoQ10 Lemon by Nordic Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • “Total Omega-3 Fatty Acids” is listed as a grouped ingredient — the label gives one combined amount (1,280 mg) without saying how much of each component you get.

This product contains 3 active ingredients: two omega-3 fatty acids (eicosapentaenoic acid and docosahexaenoic acid, derived from fish oil) and Coenzyme Q10. The omega-3s support heart and brain health, while CoQ10 is an antioxidant your body makes naturally — it helps cells produce energy and is found in higher amounts in the heart, liver, and kidneys.

The capsules also contain inactive ingredients like gelatin, glycerin, and beeswax for the softgel format, plus natural lemon flavor and antioxidants like rosemary extract and vitamin E.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: cardiovascular health and cellular energy support.
  • We looked for evidence on: Angina, Cardiovascular disease (CVD), Congestive heart failure (CHF), Hyperlipidemia, Hypertension, Hypertrophic cardiomyopathy — and 4 related terms.
  • The strongest evidence on file: Coenzyme Q10 is rated "Likely Effective" for Coenzyme Q10 deficiency (Natural Medicines).
  • Also on file: Coenzyme Q10 is rated "Possibly Effective" for Congestive heart failure (CHF), Myocardial infarction (MI).
  • Also on file: Coenzyme Q10 is rated "Insufficient Reliable Evidence To Rate" for Angina, Cardiovascular disease (CVD), Hyperlipidemia, Hypertension.

CoQ10, one of the active ingredients, is rated Likely Effective for CoQ10 deficiency and Possibly Effective for fibromyalgia, migraine headaches, congestive heart failure, and diabetic nerve pain. We don't hold effectiveness data in our system for the omega-3 fatty acids in this product, so we can't speak to their evidence base from our facts alone.

The evidence, ingredient by ingredient Coenzyme Q10

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

CoQ10 is generally well tolerated by most adults when used as directed. The most common side effects are gastrointestinal — appetite suppression, diarrhea, stomach discomfort, heartburn, nausea, and vomiting — though these occur in less than 1% of people taking it.

Dividing doses above 100 mg per day can help minimize these. Headache, dizziness, and insomnia have also been reported.

Skin itching and allergic rash are rare. Safety data during pregnancy is not on file for CoQ10, and breastfeeding safety hasn't been well studied, so talk with your doctor before using this product if you're pregnant or nursing.

Side effects, ingredient by ingredient Coenzyme Q10

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Coenzyme Q10.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 198 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before using this product if you take warfarin (Coumadin) or other blood thinners, blood pressure medications, or chemotherapy drugs — especially alkylating agents like cyclophosphamide. CoQ10 may reduce how well these medications work or cause unwanted added effects.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a reasonable choice if you're looking to support heart health with omega-3s and CoQ10, especially if you have a CoQ10 deficiency or migraine headaches. But if you take warfarin, blood pressure medications, or chemotherapy drugs, you need to check with your pharmacist first — CoQ10 can interfere with how these work.

Pregnancy and breastfeeding also warrant a conversation with your doctor.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Ultimate Omega + CoQ10 Lemon, straight from the product label.

Brand Nordic Naturals
Barcode (UPC) 768990018909
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Aug 24, 2023
DSLD ID 288740
Product type Other Combinations
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Ultimate Omega + CoQ10 Lemon by Nordic Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
30
UPC/BARCODE
768990018909
IngredientAmount% DV
Calories20 Calorie(s)--
Eicosapentaenoic Acid650 mg--
Docosahexaenoic Acid450 mg--
Cholesterol5 mg--
Total Fat2 Gram(s)3%
Saturated Fat0 Gram(s)--
Trans Fat0 Gram(s)--
Coenzyme Q-10100 mg--
Total Omega-3 Fatty Acids1280 mg--

Other ingredients: purified deep sea Fish Oil, Gelatin, Glycerin, Water, Purified, Carob, natural Lemon flavor, Coenzyme Q-10, Beeswax, D-Alpha Tocopherol, Rosemary Extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Ultimate Omega + CoQ10 offers a blend of high-intensity omega-3, plus 100 mg CoQ10 for cardiovascular health, normal cellular energy levels, and antioxidant support. This unique formulation supports the heart and the body's overall energy needs.

#1 fish oil brand in the USA Based on ClearCut, Nielsen, and SPINS annual sales data in the U.S.

Great lemon taste 1280 mg omega-3 100 mg coenzyme Q10

Less than 5 mg of cholesterol per serving.

Formulation

Certified sustainable Superior absorption No fishy aftertaste

This product and its ingredients do not contain common GE genes or proteins. Visitigenprogram.com

For cardiovascular health and antioxidant support

No gluten, milk derivatives, or artificial colors or flavors.

Fish oil processed in Norway

IGEN Non GMO Tested

Suggested/Recommended/Usage/Directions

Suggested use: Two soft gels daily, with food, or as directed by your health care professional.

Storage

Store in a cool, dry place, away from sunlight.

Precautions

Do not take if tamper-evident seal is broken or missing.

Keep out of reach of children.

Warning: Consult with your physician before taking this product if you have a known medical condition, are taking medications (including blood thinners), or if you are allergic to iodine.

Warning: Consult with your physician before taking this product if you have a known medical condition, are taking medications (including blood thinners), or if you are allergic to iodine.

Brand IP Statement(s)

Product protected by U.S. patent #s 6346231 & 6641837.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

3rd Party Purity Tested IGEN Non GMO Tested Friend of the Sea Certified Sustainable

FDA Statement of Identity

Fish Oil Supplement

General Statements

Please recycle this container

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Ultimate Omega + CoQ10 Lemon by Nordic Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Ultimate Omega + CoQ10 Lemon label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Ultimate Omega + CoQ10 Lemon by Nordic Naturals

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Coenzyme Q-10

Interacts with
198 drugs
100 mg per serving Form: Ubiquinone

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...

Coenzyme Q-10 monograph & interactions

Total Omega-3 Fatty Acids

1280 mg per serving Form: Docosahexaenoic Acid, Eicosapentaenoic Acid, Other Omega-3 Fatty Acids
  • › Eicosapentaenoic Acid
  • › Docosahexaenoic Acid

Other (inactive) ingredients: Purified deep sea Fish Oil, Gelatin, Glycerin, Water, Purified, Carob, Natural Lemon flavor, Coenzyme Q-10, Beeswax, D-Alpha Tocopherol, Rosemary Extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Ultimate Omega + CoQ10 Lemon by Nordic Naturals Drug Interactions

Want to check YOUR meds against Ultimate Omega + CoQ10 Lemon?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
198Drugs
26 Moderate 172 Minor

Ingredients driving the most interactions

Coenzyme Q-10 198

Individual Drug Interactions

The ingredients in Ultimate Omega + CoQ10 Lemon interact with 198 drugs. Click any drug to see the details.

1 of the 3 ingredients in Ultimate Omega + CoQ10 Lemon interact with drugs. Each result below shows which ingredient is responsible. Coenzyme Q-10

Each ingredient & the kinds of drugs it affects

For each ingredient in Ultimate Omega + CoQ10 Lemon with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Coenzyme Q-103 drug types · 198 drugs

Alkylating Agents

Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.

Likelihood Possible Evidence B
Coenzyme Q-10 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Ultimate Omega + CoQ10 Lemon, from the product label.

Nordic Naturals

See all Nordic Naturals products
Name
Nordic Naturals, Mfg.
Street Address
111 Jennings Drive
City
Watsonville
State
CA
ZipCode
95076
Phone Number
800.662.2544
Web Address
nordic.com
Pharmacist Counseling Corner

Ultimate Omega + CoQ10 Lemon by Nordic Naturals: Common Questions

Does Ultimate Omega + CoQ10 Lemon by Nordic Naturals interact with any medications?
Yes. Based on its ingredients, Ultimate Omega + CoQ10 Lemon has a known interaction with 198 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Ultimate Omega + CoQ10 Lemon contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's CoQ10 and why is it in here?
CoQ10 is a substance your body makes naturally to help your cells produce energy. It's found naturally in the heart, liver, and kidneys. The product includes it because it's Possibly Effective for heart failure, migraines, and nerve pain, and Likely Effective if you're deficient in it.
Can I take this if I'm on warfarin?
Not without checking with your pharmacist first. CoQ10 may work like vitamin K and reduce how well warfarin prevents blood clots. Four cases of reduced warfarin effectiveness have been reported. Your pharmacist needs to monitor you or adjust your dose.
What side effects should I expect?
Most people tolerate it well. If side effects occur, they're usually mild gastrointestinal ones — nausea, heartburn, diarrhea — in less than 1% of users. Dividing your dose if it's above 100 mg per day can help. Headache, dizziness, and skin itching have been reported rarely.
Is it safe during pregnancy?
We don't have enough safety data to say. Talk with your doctor or pharmacist for personalized advice if you're pregnant or planning to become pregnant.
Can I take this with blood pressure medication?
You should check first. CoQ10 may lower blood pressure on its own, so taking it alongside blood pressure drugs could lower your pressure more than intended. Your pharmacist can help you figure out if it's safe or if dosing needs to change.
Does this really work for heart health?
CoQ10 is Possibly Effective for congestive heart failure. That means there's some clinical evidence it helps, but it's not proven to be as reliably effective as we'd like. It's Likely Effective if you actually have a CoQ10 deficiency.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Ultimate Omega + CoQ10 Lemon is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Ultimate Omega + CoQ10 Lemon label
Go deeper

The Full Monographs Behind Ultimate Omega + CoQ10 Lemon’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Coenzyme Q10

Interacts with 198 drugs

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated and is most studied for heart condition...

Read the full Coenzyme Q10 monograph →
Sources

Sources & How We Checked

Ultimate Omega + CoQ10 Lemon's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 40 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Coenzyme Q10 40 references
  1. Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
  2. Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
  3. Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
  4. Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
  5. Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
  6. Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
  7. Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
  8. Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
  9. Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
  10. Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
  11. Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
  12. The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
  13. Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
  14. Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
  15. Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
  16. Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
  17. Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
  18. Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
  19. Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
  20. Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
  21. Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
  22. Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
  23. Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
  24. Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
  25. Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
  26. Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
  27. Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
  28. Young, J. M., Florkowski, C. M., Molyneux, S. L., McEwan, R. G., Frampton, C. M., Nicholls, M. G., Scott, R. S., and George, P. M. A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the me
  29. Ishiyama, T., Morita, Y., Toyama, S., Yamagami, T., and Tsukamoto, N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn.Heart J 1976;17(1):32-42. PubMed
  30. Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A., Karpati, G., Andermann, F., and Arnold, D. L. Coenzyme Q10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease. Neurology 1993;43(5
  31. Malm, C., Svensson, M., Sjoberg, B., Ekblom, B., and Sjodin, B. Supplementation with ubiquinone-10 causes cellular damage during intense exercise. Acta Physiol Scand. 1996;157(4):511-512. PubMed
  32. Singh, R. B., Wander, G. S., Rastogi, A., Shukla, P. K., Mittal, A., Sharma, J. P., Mehrotra, S. K., Kapoor, R., and Chopra, R. K. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc. PubMed
  33. Digiesi V, Cantini F, and Brodbeck B. Effect of coenzyme Q10 on essential arterial hypertension. Current Therapeutic Research 1990;47(5):841-845.
  34. Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.
  35. Alehagen U, Johansson P, Bjornstedt M, et al. Cardiovascular mortality and N-terminal-proBNP reduced after combined selenium and coenzyme Q10 supplementation: A 5-year prospective randomized double-blind placebo-controlled trial among elderly Swedish citi
  36. Ho MJ, Li EC, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension. Cochrane Database Syst Rev. 2016 Mar 3;3:CD007435. doi: 10.1002/14651858.CD007435.pub3. PubMed
  37. Tabrizi R, Akbari M, Sharifi N, Lankarani KB, Moosazadeh M, Kolahdooz F, et al. The effects of coenzyme Q10 supplementation on blood pressures among patients with metabolic diseases: a systematic review and meta-analysis of randomized controlled trials. PubMed
  38. Tsai IC, Hsu CW, Chang CH, Tseng PT, Chang KV. Effectiveness of coenzyme Q10 supplementation for reducing fatigue: A systematic review and meta-analysis of randomized controlled trials. Front Pharmacol 2022;13:883251. PubMed
  39. Yaghini O, Hoseini N, Ghazavi MR, et al. A comparative study on the efficacy of coenzyme Q10 and amitriptyline in the prophylactic treatment of migraine headaches in children: A randomized controlled trial. Adv Biomed Res 2022;11:43. PubMed
  40. Hansen KS, Mogensen TH, Agergaard J, et al. High-dose coenzyme Q10 therapy versus placebo in patients with post COVID-19 condition: A randomized, phase 2, crossover trial. Lancet Reg Health Eur 2022. PubMed

See these in context on the Coenzyme Q10 monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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