Vitomanhills Ingredients & Drug Interactions
by Herbal Hills
What is this page for?
First and foremost: checking Vitomanhills against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Vitomanhills is a dietary supplement by Herbal Hills with 12 active ingredients. Its ingredients are commonly taken for stress and anxiety, sleep problems, fatigue and low energy.Based on those ingredients, 1,431 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Ashwagandha, Jatiphala, Krounchabeej Ghana. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Vitomanhills by Herbal Hills
Ask about any prescription or over-the-counter medication and we check it for interactions with Vitomanhills by Herbal Hills — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Vitomanhills by Herbal Hills
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Vitomanhills contains 12 ingredients prepared using traditional Siddha methods. The active ingredients we can identify include ashwagandha (an adaptogenic herb), shatavari (asparagus racemosus), safed musli, jatiphala (mace), cowhage (which contains the compound levodopa), akkalkara (pellitory), and several others including vidarikanda, kokilaksha, masha, and shuddha shilajit.
The product also includes cow milk and go-ghruta (ghee preparations). There are no inactive fillers or excipients listed.
Does it work?
Moderate evidence
Ashwagandha in this formula is possibly effective for insomnia, anxiety, stress, and generalized anxiety disorder. Evidence for its use in bipolar disorder is insufficient.
Shatavari and safed musli lack reliable evidence for their traditional uses — the data we hold shows insufficient evidence for lactation support, muscle strength, sexual desire, bronchitis, athletic performance, and other claims. The effectiveness of the remaining ingredients has not been established in the data we hold.
How safe is it?
Well-documented data
Ashwagandha is generally well tolerated short-term in healthy adults, though long-term safety data are limited. Most common side effects are mild (diarrhea, nausea, upset stomach), but rare cases of liver damage have been reported.
Ashwagandha is considered likely unsafe in pregnancy and should be avoided while breastfeeding. Shatavari is traditionally used to support milk supply but lacks reliable safety data; it should be avoided in pregnancy unless a doctor advises otherwise.
Safed musli has limited safety data and should be avoided during pregnancy and breastfeeding unless medically advised. Jatiphala (mace) is safe in food amounts but large or concentrated doses can be toxic; medicinal amounts should be avoided in pregnancy, though food-level use is likely fine.
Cowhage contains levodopa and requires careful use with professional guidance; it should be avoided in pregnancy and breastfeeding due to its dopamine effects. Akkalkara may cause mouth irritation or allergic reactions and should be avoided in pregnancy and breastfeeding due to insufficient safety data.
Meds to double-check
Major interaction found
Stop and check with your pharmacist if you take methyldopa or any monoamine oxidase inhibitor (MAOI), as cowhage creates Major interactions with both. Also verify any levodopa, blood pressure medications, diabetes drugs, antipsychotics, tricyclic antidepressants, thyroid hormones, immune-suppressing medications, diuretics, lithium, or the anesthetic phenobarbital before adding this product.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.
This product combines traditional Ayurvedic herbs and should only be used under professional guidance, especially because cowhage contains levodopa — a potent compound with serious drug interactions. If you take any blood pressure medication, diabetes drug, antidepressant, antipsychotic, thyroid medication, or immune-suppressing drug, talk to your pharmacist before starting.
Women who are pregnant or breastfeeding should avoid it.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 6 of 12 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Vitomanhills, straight from the product label.
| Brand | Herbal Hills |
|---|---|
| Barcode (UPC) | 8906008260403 |
| Net contents | 900 Soft Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jun 24, 2019 |
| DSLD ID | 203950 |
| Product type | Other Combinations |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult Male (18-50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Vitomanhills by Herbal Hills, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Processed by the method of Siddha Ghruta in | 0 NP | -- |
| Cow Milk | 500 mg | -- |
| Ashwagandha | 117.65 mg | -- |
| Quath Dravya of | 0 NP | -- |
| Go-Ghruta | 500 mg | -- |
| Shatavari | 39.2 mg | -- |
| Safed Musli | 39.2 mg | -- |
| Vidarikanda | 39.2 mg | -- |
| Kokilaksha | 39.2 mg | -- |
| Jatiphala | 9.8 mg | -- |
| Masha | 39.2 mg | -- |
| Shuddha Shilajit | 39.2 mg | -- |
| Akkalkara | 19.6 mg | -- |
| Krounchabeej Ghana | 117.65 mg | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
Herbal Supplement
Formula
Herbal Formulation processed with Cow Ghee
Men's Health
General Statements
Mfg. Lic. No. MB/AYU/001-A/11 M.R.P. (Inclusive of all taxes)
Ayurvedic Proprietary Medicine
Permitted colours used in capsule shell
Customer Care: 91 22 28686868 (10 a.m to 6 p.m on weekdays) 110716
Seals/Symbols
GMP Good Manufacturing Practice
Storage
Store in a cool dry place away from direct sunlight
Precautions
Keep out of reach of children.
Do not use if inner seal is broken or missing
Suggested/Recommended/Usage/Directions
Direction for use: Take 2 soft gel capsules daily in the morning or as recommended by the physician. It should ideally be taken on empty stomach before meals. For better results it should be taken with warm water or milk
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Vitomanhills by Herbal Hills label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Vitomanhills by Herbal Hills
These are the 12 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Not Present Dosage formSoftgel Capsule Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Processed by the method of Siddha Ghruta in
- › Cow Milk
- › Go-Ghruta
Quath Dravya of
- › Ashwagandha
- › Shatavari
- › Safed Musli
- › Vidarikanda
- › Kokilaksha
- › Jatiphala
- › Masha
- › Shuddha Shilajit
- › Akkalkara
- › Krounchabeej Ghana
Vitomanhills by Herbal Hills Drug Interactions
HelloPharmacist Interaction Report
Vitomanhills by Herbal Hills contains several ingredients with documented interactions.
The most serious concern is cowhage (Krounchabeej Ghana), which contains levodopa and interacts with methyldopa and monoamine oxidase inhibitors (MAOIs) at Major severity — both can trigger dangerous blood pressure spikes or drops. Cowhage also has Major interactions with levodopa itself and moderate interactions with antidiabetes drugs (low blood sugar risk), antipsychotics, tricyclic antidepressants, certain anesthetics, and guanethidine.
Read the full breakdown — every affected drug type, severity by severity
Ashwagandha carries Moderate interactions across multiple drug types: CNS depressants and benzodiazepines (increased drowsiness), blood pressure medications (risk of low blood pressure), immune-suppressing drugs, diabetes medications (low blood sugar risk), thyroid hormones (amplified effects and side effects), liver-toxic drugs, and a Minor interaction with certain enzyme substrates. Jatiphala (mace) also has Moderate interactions with CNS depressants, certain enzyme substrates, immune-suppressing drugs, and phenobarbital.
Shatavari interacts moderately with diuretics and lithium.
We could not check Cow Milk, Go-Ghruta, Vidarikanda, Kokilaksha, Masha, or Shuddha Shilajit — we hold no interaction data for these ingredients. Safed Musli and Akkalkara (pellitory) were checked and have no interactions documented in our data.
Altogether, these interactions span 1,410 individual medications. Use the medication checker below to verify your exact prescriptions before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Vitomanhills?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Vitomanhills interact with 1,431 drugs. Click any drug to see the details.
4 of the 12 ingredients in Vitomanhills interact with drugs. Each result below shows which ingredient is responsible. Ashwagandha Jatiphala Krounchabeej Ghana Shatavari
AmphetamineAdensys XR-ODT, Adzenys ER, Dyanavel XR, Mydayis
How Amphetamine interacts with Vitomanhills — through 1 ingredient. Tap an ingredient for the detail:
Krounchabeej GhanaMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Krounchabeej Ghana + Amphetamine interactionBenserazide, LevodopaMadopar, Prolopa
How Benserazide, Levodopa interacts with Vitomanhills — through 1 ingredient. Tap an ingredient for the detail:
Krounchabeej GhanaLevodopa Major
Interaction Summary
Concomitant use can increase the risk of levodopa-related adverse effects.
Read the full Krounchabeej Ghana + Benserazide, Levodopa interactionCarbidopa, LevodopaDhivy, Rytary, Sinemet, Sinemet CR
How Carbidopa, Levodopa interacts with Vitomanhills — through 1 ingredient. Tap an ingredient for the detail:
Krounchabeej GhanaLevodopa Major
Interaction Summary
Concomitant use can increase the risk of levodopa-related adverse effects.
Read the full Krounchabeej Ghana + Carbidopa, Levodopa interactionCarbidopa, Levodopa, EntacaponeStalevo
How Carbidopa, Levodopa, Entacapone interacts with Vitomanhills — through 1 ingredient. Tap an ingredient for the detail:
Krounchabeej GhanaLevodopa Major
Interaction Summary
Concomitant use can increase the risk of levodopa-related adverse effects.
Read the full Krounchabeej Ghana + Carbidopa, Levodopa, Entacapone interactionChlorothiazide, MethyldopaAldochlor, Aldoclor 150, Aldoclor 250
How Chlorothiazide, Methyldopa interacts with Vitomanhills — through 3 ingredients. Tap an ingredient for the detail:
Krounchabeej GhanaMethyldopa (aldomet) Major
Interaction Summary
Theoretically, concomitant use of cowhage and methyldopa might increase the risk of hypotension.
Read the full Krounchabeej Ghana + Chlorothiazide, Methyldopa interactionShatavariDiuretic Drugs Moderate
Interaction Summary
Theoretically, asparagus racemosus root might increase diuresis and electrolyte loss when used with diuretic drugs.
Read the full Shatavari + Chlorothiazide, Methyldopa interactionAshwagandhaHepatotoxic Drugs, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Ashwagandha + Chlorothiazide, Methyldopa interactionHydrochlorothiazide, MethyldopaAldoril 15, Aldoril 25, Aldoril D30, Methazide
How Hydrochlorothiazide, Methyldopa interacts with Vitomanhills — through 3 ingredients. Tap an ingredient for the detail:
Krounchabeej GhanaMethyldopa (aldomet) Major
Interaction Summary
Theoretically, concomitant use of cowhage and methyldopa might increase the risk of hypotension.
Read the full Krounchabeej Ghana + Hydrochlorothiazide, Methyldopa interactionAshwagandhaHepatotoxic Drugs, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Ashwagandha + Hydrochlorothiazide, Methyldopa interactionShatavariDiuretic Drugs Moderate
Interaction Summary
Theoretically, asparagus racemosus root might increase diuresis and electrolyte loss when used with diuretic drugs.
Read the full Shatavari + Hydrochlorothiazide, Methyldopa interactionIsocarboxazidMarplan
How Isocarboxazid interacts with Vitomanhills — through 2 ingredients. Tap an ingredient for the detail:
Krounchabeej GhanaMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Krounchabeej Ghana + Isocarboxazid interactionAshwagandhaSerotonergic Drugs Minor
Interaction Summary
Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors.
Read the full Ashwagandha + Isocarboxazid interactionLevodopaInbrija, Larodopa
How Levodopa interacts with Vitomanhills — through 1 ingredient. Tap an ingredient for the detail:
Krounchabeej GhanaLevodopa Major
Interaction Summary
Concomitant use can increase the risk of levodopa-related adverse effects.
Read the full Krounchabeej Ghana + Levodopa interactionLevodopa, CarbidopaDuodopa
How Levodopa, Carbidopa interacts with Vitomanhills — through 1 ingredient. Tap an ingredient for the detail:
Krounchabeej GhanaLevodopa Major
Interaction Summary
Concomitant use can increase the risk of levodopa-related adverse effects.
Read the full Krounchabeej Ghana + Levodopa, Carbidopa interactionMethyldopaAldomet, Methyldopa
How Methyldopa interacts with Vitomanhills — through 2 ingredients. Tap an ingredient for the detail:
Krounchabeej GhanaMethyldopa (aldomet) Major
Interaction Summary
Theoretically, concomitant use of cowhage and methyldopa might increase the risk of hypotension.
Read the full Krounchabeej Ghana + Methyldopa interactionAshwagandhaAntihypertensive Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Read the full Ashwagandha + Methyldopa interactionMoclobemideManerix, Moclobemide
How Moclobemide interacts with Vitomanhills — through 1 ingredient. Tap an ingredient for the detail:
Krounchabeej GhanaMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Krounchabeej Ghana + Moclobemide interactionOzanimod HydrochlorideZeposia
How Ozanimod Hydrochloride interacts with Vitomanhills — through 3 ingredients. Tap an ingredient for the detail:
Krounchabeej GhanaMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Krounchabeej Ghana + Ozanimod Hydrochloride interactionAshwagandhaHepatotoxic Drugs, Immunosuppressants Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Ashwagandha + Ozanimod Hydrochloride interactionJatiphalaImmunosuppressants Moderate
Interaction Summary
Animal research suggests that mace lignans can suppress immune function.
Read the full Jatiphala + Ozanimod Hydrochloride interactionPhenelzine SulfateNardil
How Phenelzine Sulfate interacts with Vitomanhills — through 3 ingredients. Tap an ingredient for the detail:
Krounchabeej GhanaMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Krounchabeej Ghana + Phenelzine Sulfate interactionJatiphalaCns Depressants Moderate
Interaction Summary
Several volatile oils in mace, such as methyleugenol, isoeugenol, safrole, myristicin, 1,8-cineole, and geranyl acetate, seem to have sedative effects.
Read the full Jatiphala + Phenelzine Sulfate interactionAshwagandhaCns Depressants, Serotonergic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Read the full Ashwagandha + Phenelzine Sulfate interactionRasagilineAzilect
How Rasagiline interacts with Vitomanhills — through 3 ingredients. Tap an ingredient for the detail:
Krounchabeej GhanaMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Krounchabeej Ghana + Rasagiline interactionJatiphalaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Animal research suggests that intraperitoneal injections of myristicin, a constituent of mace, can induce cytochrome P450 1A2 (CYP1A2) enzyme system.
Read the full Jatiphala + Rasagiline interactionAshwagandhaSerotonergic Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors.
Read the full Ashwagandha + Rasagiline interactionSafinamide MesylateXadago
How Safinamide Mesylate interacts with Vitomanhills — through 2 ingredients. Tap an ingredient for the detail:
Krounchabeej GhanaMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Krounchabeej Ghana + Safinamide Mesylate interactionAshwagandhaSerotonergic Drugs Minor
Interaction Summary
Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors.
Read the full Ashwagandha + Safinamide Mesylate interactionSelegilineCarbex, Eldepryl, Emsam, Zelapar
How Selegiline interacts with Vitomanhills — through 2 ingredients. Tap an ingredient for the detail:
Krounchabeej GhanaMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Krounchabeej Ghana + Selegiline interactionAshwagandhaSerotonergic Drugs Minor
Interaction Summary
Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors.
Read the full Ashwagandha + Selegiline interactionTranylcypromineParnate
How Tranylcypromine interacts with Vitomanhills — through 2 ingredients. Tap an ingredient for the detail:
Krounchabeej GhanaMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Read the full Krounchabeej Ghana + Tranylcypromine interactionAshwagandhaSerotonergic Drugs Minor
Interaction Summary
Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors.
Read the full Ashwagandha + Tranylcypromine interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Vitomanhills — through 2 ingredients. Tap an ingredient for the detail:
JatiphalaImmunosuppressants Moderate
Interaction Summary
Animal research suggests that mace lignans can suppress immune function.
Read the full Jatiphala + 6-mercaptopurine interactionAshwagandhaImmunosuppressants, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha might decrease the effects of immunosuppressants.
Read the full Ashwagandha + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Vitomanhills — through 1 ingredient. Tap an ingredient for the detail:
AshwagandhaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Ashwagandha + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Vitomanhills — through 1 ingredient. Tap an ingredient for the detail:
AshwagandhaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Ashwagandha + Abacavir, Lamivudine interactionAbiraterone
How Abiraterone interacts with Vitomanhills — through 1 ingredient. Tap an ingredient for the detail:
AshwagandhaCytochrome P450 3a4 (cyp3a4) Substrates, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Ashwagandha + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Vitomanhills — through 1 ingredient. Tap an ingredient for the detail:
AshwagandhaHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Ashwagandha + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Vitomanhills — through 2 ingredients. Tap an ingredient for the detail:
JatiphalaImmunosuppressants Moderate
Interaction Summary
Animal research suggests that mace lignans can suppress immune function.
Read the full Jatiphala + Abrocitinib interactionAshwagandhaImmunosuppressants Moderate
Interaction Summary
Theoretically, taking ashwagandha might decrease the effects of immunosuppressants.
Read the full Ashwagandha + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Vitomanhills — through 2 ingredients. Tap an ingredient for the detail:
Krounchabeej GhanaAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of cowhage and antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Krounchabeej Ghana + Acarbose interactionAshwagandhaHepatotoxic Drugs, Antidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Ashwagandha + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Vitomanhills — through 1 ingredient. Tap an ingredient for the detail:
AshwagandhaAntihypertensive Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Read the full Ashwagandha + Acebutolol interactionAcepromazineAtravet
How Acepromazine interacts with Vitomanhills — through 3 ingredients. Tap an ingredient for the detail:
Krounchabeej GhanaAntipsychotic Drugs Moderate
Interaction Summary
Theoretically, use of cowhage might decrease the clinical effects of antipsychotic drugs.
Read the full Krounchabeej Ghana + Acepromazine interactionAshwagandhaCns Depressants Moderate
Interaction Summary
Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Read the full Ashwagandha + Acepromazine interactionJatiphalaCns Depressants Moderate
Interaction Summary
Several volatile oils in mace, such as methyleugenol, isoeugenol, safrole, myristicin, 1,8-cineole, and geranyl acetate, seem to have sedative effects.
Read the full Jatiphala + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Vitomanhills — through 2 ingredients. Tap an ingredient for the detail:
AshwagandhaHepatotoxic Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Ashwagandha + Acetaminophen interactionJatiphalaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Animal research suggests that intraperitoneal injections of myristicin, a constituent of mace, can induce cytochrome P450 1A2 (CYP1A2) enzyme system.
Read the full Jatiphala + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Vitomanhills — through 2 ingredients. Tap an ingredient for the detail:
JatiphalaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Animal research suggests that intraperitoneal injections of myristicin, a constituent of mace, can induce cytochrome P450 1A2 (CYP1A2) enzyme system.
Read the full Jatiphala + Acetaminophen, Aspirin interactionAshwagandhaCytochrome P450 1a2 (cyp1a2) Substrates, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, ashwagandha might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Ashwagandha + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Vitomanhills — through 2 ingredients. Tap an ingredient for the detail:
AshwagandhaHepatotoxic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Read the full Ashwagandha + Acetaminophen, Aspirin, Caffeine interactionJatiphalaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Animal research suggests that intraperitoneal injections of myristicin, a constituent of mace, can induce cytochrome P450 1A2 (CYP1A2) enzyme system.
Read the full Jatiphala + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Vitomanhills — through 2 ingredients. Tap an ingredient for the detail:
JatiphalaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Animal research suggests that intraperitoneal injections of myristicin, a constituent of mace, can induce cytochrome P450 1A2 (CYP1A2) enzyme system.
Read the full Jatiphala + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAshwagandhaCytochrome P450 1a2 (cyp1a2) Substrates, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, ashwagandha might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Ashwagandha + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Vitomanhills with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Ashwagandha
Antidiabetes Drugs
Theoretically, taking ashwagandha with antidiabetes drugs might increase the risk of hypoglycemia.
There is preliminary clinical evidence suggesting that ashwagandha might lower blood glucose levels. Theoretically, ashwagandha might have additive effects when used with antidiabetes drugs and increase the risk of hypoglycemia.
Antihypertensive Drugs
Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Animal research suggests that ashwagandha might lower systolic and diastolic blood pressure. Theoretically, ashwagandha might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Benzodiazepines
Theoretically, taking ashwagandha might increase the sedative effects of benzodiazepines.
There is preliminary evidence that ashwagandha might have an additive effect with diazepam (Valium) and clonazepam (Klonopin). This may also occur with other benzodiazepines.
Cns Depressants
Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Ashwagandha seems to have sedative effects. Theoretically, this may potentiate the effects of barbiturates, other sedatives, and anxiolytics.
Hepatotoxic Drugs
Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Ashwagandha has been linked to cases of acute hepatitis, liver failure, hepatic encephalopathy, autoimmune hepatitis, the need for liver transplantation, and death due to liver failure.
Immunosuppressants
Theoretically, taking ashwagandha might decrease the effects of immunosuppressants.
Ashwagandha has demonstrated immunostimulant effects in humans. Animal research has shown that ashwagandha can attenuate the immunosuppression caused by cyclophosphamide.
Thyroid Hormone
Ashwagandha might increase the effects and adverse effects of thyroid hormone.
Concomitant use of ashwagandha with thyroid hormones may cause additive therapeutic and adverse effects. Preliminary clinical research and animal studies suggest that ashwagandha boosts thyroid hormone synthesis and secretion. In one clinical study, ashwagandha increased triiodothyronine (T3) and thyroxine (T4) levels by 41.5% and 19.6%, respectively, and reduced serum TSH levels by 17.4% from baseline in adults with subclinical hypothyroidism.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, ashwagandha might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that ashwagandha extract induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that ashwagandha extract induces CYP3A4 enzymes.
Serotonergic Drugs
Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors. However, there is no evidence to suggest that ashwagandha increases the risk of serotonin-related effects, and there have been no published case reports of serotonin syndrome when combined with other serotonergic drugs. Nevertheless, due to the lack of extensive studies on the matter and the fact that ashwagandha appears to affect serotonergic pathways, it would be prudent to exercise caution when combining it with drugs that affect serotonin. [References: - Effects of Withania somnifera (Ashwaga ndha) on Stress and the Stress-Related Neuropsychiatric Disorders Anxiety, Depression, and Insomnia. Curr Neuropharmacol. 2021 Sep 14; 19: 1468–1495. - A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573577/]
Jatiphala
Cns Depressants
Several volatile oils in mace, such as methyleugenol, isoeugenol, safrole, myristicin, 1,8-cineole, and geranyl acetate, seem to have sedative effects. Evidence from animal research suggests that methyleugenol can induce anesthesia for a similar duration as pentobarbital. Due to the sedative effects of certain mace constituents, taking medicinal amounts of mace in combination with other CNS depressants may have additive effects. However, evidence from other animal research suggests that myristicin can reduce sleeping time in rats pretreated with phenobarbital. Until more is known, use medicinal amounts of mace cautiously in combination with CNS depressants. Some CNS depressants include clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), and others.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Animal research suggests that intraperitoneal injections of myristicin, a constituent of mace, can induce cytochrome P450 1A2 (CYP1A2) enzyme system. Theoretically, concomitant use of mace with drugs metabolized by CYP1A2 may increase the clearance of these drugs and reduce their effects. Some substrates of CYP1A2 include clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Talwin), propranolol (Inderal), tacrine (Cognex), theophylline, zileuton (Zyflo), zolmitriptan (Zomig), and others.
Immunosuppressants
Animal research suggests that mace lignans can suppress immune function. Theoretically, concomitant use might enhance the effects of immunosuppressant drugs. Immunosuppressant drugs include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), and other corticosteroids (glucocorticoids).
Phenobarbital (Luminal)
Evidence from animal research suggests that myristicin, a constituent of mace, can reduce sleeping time in rats pretreated with phenobarbital. Theoretically, concomitant use may decrease the therapeutic effects of phenobarbital.
Krounchabeej Ghana
Levodopa
Concomitant use can increase the risk of levodopa-related adverse effects.
Cowhage contains levodopa. Some cowhage products have been standardized to contain 75-400 mg of levodopa per dose.
Methyldopa (Aldomet)
Theoretically, concomitant use of cowhage and methyldopa might increase the risk of hypotension.
Cowhage contains levodopa. Use of levodopa with methyldopa might cause additive hypotension. In addition, methyldopa may inhibit peripheral decarboxylation of levodopa and increase levodopa levels in the central nervous system; avoid using.
Monoamine Oxidase Inhibitors (Maois)
Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Cowhage contains levodopa. Use of levodopa with non-selective MAOIs might cause hypertensive crisis. However, this interaction has not been reported with MAO-B selective inhibitors such as selegiline.
Anesthesia
Theoretically, concomitant use of cowhage and anesthesia might increase the risk of arrhythmias.
Cowhage contains levodopa. Use of levodopa with cyclopropane or halogenated hydrocarbon anesthesia has led to arrhythmias. Other anesthetics have not been implicated. Use other anesthetics in patients taking cowhage or tell patients to stop taking cowhage at least 2 weeks before surgery.
Antidiabetes Drugs
Theoretically, concomitant use of cowhage and antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that cowhage might have hypoglycemic effects.
Antipsychotic Drugs
Theoretically, use of cowhage might decrease the clinical effects of antipsychotic drugs.
Cowhage contains levodopa. Use of levodopa might counteract the antidopaminergic effects of antipsychotic medications.
Guanethidine (Ismelin)
Theoretically, concomitant use of cowhage and guanethidine might increase the risk of hypotension.
Cowhage contains levodopa. Use of levodopa with guanethidine might cause additive hypotension; avoid using.
Tricyclic Antidepressants (Tcas)
Theoretically, use of TCAs might reduce the levels and clinical effects of cowhage.
Cowhage contains levodopa. Use of TCAs might reduce the absorption of levodopa. Some case reports describe patients that developed hypertension and dyskinesia when taking both levodopa and TCAs.
Shatavari
Diuretic Drugs
Theoretically, asparagus racemosus root might increase diuresis and electrolyte loss when used with diuretic drugs.
Animal studies show that asparagus racemosus root has diuretic effects when used in high doses. This effect has not been reported in humans.
Lithium
Theoretically, Asparagus racemosus root could reduce excretion and increase levels of lithium.
Animal research suggests that Asparagus racemosus root has diuretic properties when used in high doses. Therefore, it might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
Brand information
Manufacturer and brand details for Vitomanhills, from the product label.
Herbal Hills
See all Herbal Hills products- Name
- Isha Agro Developers Pvt. Ltd.
- Street Address
- Plot # 33, Govt. Indl. Estate, Charkop,
- City
- Kandivali (W), Mumbai-400 067
- State
- Maharashtra
- Phone Number
- 91 22 28686868
- Web Address
- www.herbalhills.in
Vitomanhills by Herbal Hills: Common Questions
Does Vitomanhills by Herbal Hills interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is cowhage and why is it in this formula?
Can I take Vitomanhills while pregnant or breastfeeding?
What are the most common side effects?
Does ashwagandha really help with sleep and anxiety?
Is this product safe to use long-term?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Vitomanhills is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Vitomanhills’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Ashwagandha
Interacts with 1,372 drugsAshwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, though the evidence is still limited. It is generally w...
Read the full Ashwagandha monograph → Herb & supplement monographAsparagus Racemosus
Interacts with 76 drugsAsparagus racemosus, often called shatavari, is an Ayurvedic herb traditionally used to support women's health, digestion, and overall vitality. Human evidence for most of these uses is limi...
Read the full Asparagus Racemosus monograph → Herb & supplement monographSafed Musli
Safed Musli is an Ayurvedic herb traditionally used as a tonic and aphrodisiac, especially for male sexual health and energy. Human evidence is limited and mostly preliminary, so its benefit...
Read the full Safed Musli monograph → Herb & supplement monographMace
Interacts with 500 drugsMace is the lacy red covering of the nutmeg seed and comes from the same tree as nutmeg. It is mostly used as a cooking spice and in traditional medicine for digestion, but there is little s...
Read the full Mace monograph → Herb & supplement monographPellitory
Pellitory (often Anacyclus pyrethrum, the root traditionally called 'pellitory of Spain') is an herb chiefly known in folk and traditional medicine for numbing toothache and stimulating sali...
Read the full Pellitory monograph → Herb & supplement monographCowhage
Interacts with 193 drugsCowhage (Mucuna pruriens) is a tropical legume best known as a natural source of L-dopa, the compound the body turns into dopamine. It is most studied for Parkinson's disease symptoms and ma...
Read the full Cowhage monograph →Sources & How We Checked
Vitomanhills's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 65 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Ashwagandha 32 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Upton R, ed. Ashwagandha Root (Withania somnifera): Analytical, quality control, and therapuetic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia 2000:1-25.
- Davis L, Kuttan G. Effect of Withania somnifera on cyclophosphamide-induced urotoxicity. Cancer Lett 2000;148:9-17. PubMed
- Davis L, Kuttan G. Suppressive effect of cyclophosphamide-induced toxicity by Withania somnifera extract in mice. J Ethnopharmacol 1998;62:209-14. PubMed
- Mishra LC, Singh BB, Dagenais S. Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review. Altern Med Rev 2000;5:334-46. DOI
- Andallu B, Radhika B. Hypoglycemic, diuretic and hypocholesterolemic effect of winter cherry (Withania somnifera, Dunal) root. Indian J Exp Biol 2000;38:607-9.
- Kulkarni RR, Patki PS, Jog VP, et al. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol 1991;33:91-5. PubMed
- Ahumada F, Aspee F, Wikman G, Hancke J. Withania somnifera exract. Its effects on arterial blood pressure in anaesthetized dogs. Phytother Res 1991;5:111-14.
- Panda S, Kar A. Withania somnifera and Bauhinia purpurea in the regulation of circulating thyroid hormone concentrations in female mice. J Ethnopharmacol 1999;67:233-39. PubMed
- Panda S, Kar A. Changes in thyroid hormone concentrations after administration of ashwagandha root extract to adult male mice. J Pharm Pharmacol 1998;50:1065-68. PubMed
- Sehgal, V. N., Verma, P., and Bhattacharya, S. N. Fixed-drug eruption caused by ashwagandha (Withania somnifera): a widely used Ayurvedic drug. Skinmed. 2012;10(1):48-49.
- Agnihotri AP, Sontakke SD, Thawani VR, Saoji A, Goswami VS. Effects of Withania somnifera in patients of schizophrenia: a randomized, double blind, placebo controlled pilot trial study. Indian J Pharmacol. 2013;45(4):417-8. PubMed
- Biswal BM, Sulaiman SA, Ismail HC, Zakaria H, Musa KI. Effect of Withania somnifera (Ashwagandha) on the development of chemotherapy-induced fatigue and quality of life in breast cancer patients. Integr Cancer Ther. 2013;12(4):312-22.
- Sharma AK, Basu I, Singh S. Efficacy and safety of Ashwagandha root extract in subclinical hypothyroid patients: a double-blind, randomized placebo-controlled trial. J Altern Complement Med. 2018 Mar;24(3):243-248. PubMed
- Durg S, Bavage S, Shivaram SB. Withania somnifera (Indian ginseng) in diabetes mellitus: A systematic review and meta-analysis of scientific evidence from experimental research to clinical application. Phytother Res. 2020;34(5):1041-1059.
- Björnsson HK, Björnsson ES, Avula B, et al. Ashwagandha-induced liver injury: A case series from Iceland and the US Drug-Induced Liver Injury Network. Liver Int. 2020;40(4):825-829. PubMed
- Tharakan A, Shukla H, Benny IR, Tharakan M, George L, Koshy S. Immunomodulatory Effect of Withania somnifera (Ashwagandha) Extract-A Randomized, Double-Blind, Placebo Controlled Trial with an Open Label Extension on Healthy Participants. J Clin Med 2021;1 PubMed
- Ireland PJ, Hardy T, Burt AD, Donnelly MC. Drug-induced hepatocellular injury due to herbal supplement ashwagandha. J R Coll Physicians Edinb. 2021;51(4):363-365. PubMed
- Kamal HI, Patel K, Brdak A, Heffernan J, Ahmad N. Ashwagandha as a unique cause of thyrotoxicosis presenting with supraventricular tachycardia. Cureus. 2022 Mar 25;14(3):e23494. PubMed
- Suryawanshi G, Abdallah M, Thomson M, Desai N, Chauhan A, Lim N. Ashwagandha-Associated Acute Liver Failure Requiring Liver Transplantation. Am J Ther 2023;30(1):e80-e83. PubMed
- Pusec CM, Wolsky R, Llerena C, Sura P. A Case of Supplement-Induced Hepatitis. Cureus 2022;14(10):e30433. PubMed
- Ajgaonkar A, Jain M, Debnath K. Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract for Improvement of Sexual Health in Healthy Women: A Prospective, Randomized, Placebo-Controlled Study. Cureus 2022;14(10):e30787. PubMed
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
- Lubarska M, Halasinski P, Hryhorowicz S, et al. Liver Dangers of Herbal Products: A Case Report of Ashwagandha-Induced Liver Injury. Int J Environ Res Public Health 2023;20(5):3921. PubMed
- Tóth M, Benedek AE, Longerich T, Seitz HK. Ashwagandha-induced acute liver injury: A case report. Clin Case Rep 2023;11(3):e7078.
- Bokan G, Glamocanin T, Mavija Z, et al. Herb-Induced Liver Injury by Ayurvedic Ashwagandha as Assessed for Causality by the Updated RUCAM: An Emerging Cause. Pharmaceuticals (Basel) 2023;16(8):1129. PubMed
- Patel PA, Sanborn E, Then R, Williams DM. Recurrent Reversible Cerebral Vasoconstriction Syndrome: A Report of Two Cases. Cureus 2023;15(8):e42992. PubMed
- Majeed M, Nagabhushanam K, Murali A, Vishwanathan DT, Mamidala RV, Mundkur L. A Standardized Withania somniferra (Linn.) Root Extract with Piperine Alleviates the Symptoms of Anxiety and Depression by Increasing Serotonin Levels: A Double-Blind, Randomize
- Philips CA, Valsan A, Theruvath AH, et al. Ashwagandha-induced liver injury-A case series from India and literature review. Hepatol Commun 2023;7(10):e0270. PubMed
- Hayashi M, Hamada H, Azuma SI, Hayashi K. Painless Thyroiditis by Withania somnifera (Ashwagandha). Cureus 2024;16(3):e55352. PubMed
- Vazirani S, Kothari A, Fujimoto J, Gomez M. Supplements Are Not a Synonym for Safe: Suspected Liver Injury From Ashwagandha. Fed Pract 2023;40(9):315-319. PubMed
- Patel M, Newell R, Hillier M, Ramalingam R. Herbal remedies as a potential cause of hypoadrenalism. Br J Hosp Med (Lond) 2024;85(6):1-4. PubMed
Asparagus Racemosus 1 reference
- Satish Kumar MC, Udupa AL, Sammodavardhana K, Rathnakar UP, Shvetha U, Kodancha GP. Acute toxicity and diuretic studies of the roots of Asparagus racemosus Willd in rats. West Indian Med J. 2010;59(1):3-6.
Safed Musli 1 reference
- Tripathi RK, Dethe PD, Bhojne SK, Raut AA, Rege NN. A prospective, randomized, placebo-controlled, double-blind comparative pilot study to evaluate the efficacy of Chlorophytum borivilianum on physical performance. Indian J Pharmacol 2019;51(3):150-6. PubMed
Mace 18 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Sangalli BC, Chiang W. Toxicology of nutmeg abuse. Clin Toxicol 2000;38:671-8. PubMed
- Hallstrom H, Thuvander A. Toxicological evaluation of myristicin. Nat Toxins 1997;5:186-92. DOI
- Jeong HG, Yun CH. Induction of rat hepatic cytochrome P450 enzymes by myristicin. Biochem Biophys Res Commun 1995;217:966-71. PubMed
- McKenna A, Nordt SP, Ryan J. Acute nutmeg poisoning. Eur J Emerg Med 2004;11:240-1. PubMed
- Panayotopoulos DJ, Chisholm DD. Hallucinogenic effect of nutmeg. Br Med J 1970;1:754. PubMed
- Stein U, Greyer H, Hentschel H. Nutmeg (myristicin) poisoning-report on a fatal case and a series of cases recorded by a poison information centre. Forensic Sci Int 2001;118:87-90. PubMed
- Venables GS, Evered D, Hall R. Letter: Nutmeg poisoning. Br Med J 1976;1:96. PubMed
- Carstairs SD, Cantrell FL. The spice of life: an analysis of nutmeg exposures in California. Clin Toxicol (Phila) 2011;49:177-80. PubMed
- Abernethy MK, Becker LB. Acute nutmeg intoxication. Am J Emerg Med 1992;10:429-30. PubMed
- Checker R, Chatterjee S, Sharma D, et al. Immunomodulatory and radioprotective effects of lignans derived from fresh nutmeg mace (Myristica fragrans) in mammalian splenocytes. Int Immunopharmacol. 2008;8(5):661-669. PubMed
- Sell AB, Carlini EA. Anesthetic action of methyleugenol and other eugenol derivatives. Pharmacology. 1976;14(4):367-77. PubMed
- Fundarò A, Cassone MC. [Action of essential oils of chamomile, cinnamon, absinthium, mace and origanum on operant conditioning behavior of the rat]. Boll Soc Ital Biol Sper. 1980;56(22):2375-80.
- Grover JK, Khandkar S, Vats V, Dhunnoo Y, Das D. Pharmacological studies on Myristica fragrans--antidiarrheal, hypnotic, analgesic and hemodynamic (blood pressure) parameters. Methods Find Exp Clin Pharmacol. 2002;24(10):675-80. PubMed
- Barceloux DG. Nutmeg (Myristica fragrans Houtt.). Dis Mon. 2009;55(6):373-9. PubMed
- Dooms-Goossens, A., Dubelloy, R., and Degreef, H. Contact and systemic contact-type dermatitis to spices. Dermatol Clin 1990;8(1):89-93. DOI
- Anjum A, Sultana A. A randomized comparative study of herbal decoction of Cassia fistula Linn pod's pericarp and Myristica fragrans Houtt arils vs. mefenamic acid in spasmodic dysmenorrhoea. J Complement Integr Med. 2018;16(2):/j/jcim.2019.16.issue-2/jcim
- Najeeya AGF, Sultana A. Efficacy of mace (Arils of Myristica fragrans Houtt) plus PFMT on symptoms in mixed urinary incontinence: a randomized placebo-controlled trial. Integr Med Res. 2018;7(4):307-315.
Pellitory 1 reference
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
Cowhage 12 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Anon. Epidemiological notes and reports: Mucuna pruriens-associated pruritus--New Jersey. MMWR Morb Mortal Wkly Rep 1985;34:732-3.
- HP-200 in Parkinson's Disease study group. An alternative medicine treatment for Parkinson's disease: Results of a multicenter clinical trial. J Alt Comp Med 1995;1:249-55. DOI
- Infante ME, Perez AM, Simao MR, et al. Outbreak of acute toxic psychosis attributed to Mucuna pruriens. Lancet 1990;336:1129. PubMed
- Vaidya AB, Rajagopalan TG, Mankodi NA, et al. Treatment of Parkinson's disease with the cowhage plant-Mucuna pruriens Bak. Neurol India 1978;26:171-6.
- Vadivel V, Janardhanan K. Nutritional and anti-nutritional composition of velvet bean: an under-utilized food legume in south India. Int J Food Sci Nutr 2000;51:279-87. PubMed
- Akhtar MS, Qureshi AQ, Iqbal J. Antidiabetic evaluation of Mucuna pruriens, Linn seeds. J Pak Med Assoc 1990;40:147-50.
- Prakash, D., Niranjan, A., and Tewari, S. K. Some nutritional properties of the seeds of three Mucuna species. Int.J.Food Sci.Nutr. 2001;52(1):79-82.
- Vadivel, V. and Janardhanan, K. Nutritional and antinutritional characteristics of seven South Indian wild legumes. Plant Foods Hum.Nutr 2005;60(2):69-75. PubMed
- Creapure (Creatine Monohydrate). Toxicological Datasheet. Degussa BioActives. Available at: https://www.fda.gov/ohrms/DOCKETS/.../95s-0316-rpt0154-54-Ref-50-vol112.pdf.
- Pulikkalpura H, Kurup R, Mathew PJ, Baby S. Levodopa in Mucuna pruriens and its degradation. Sci Rep 2015;5:11078. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC