Interactions on record — worth a quick check against your medications. Based on 3 of 8 ingredients. Check your meds →
Dietary supplement

Whey Protein Natural Vanilla Flavor Ingredients & Drug Interactions

by NewtonEverett

Whey Protein Natural Vanilla Flavor label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Whey Protein Natural Vanilla Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Whey Protein Natural Vanilla Flavor is a dietary supplement by NewtonEverett with 8 active ingredients. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 340 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Stevia extract, Sodium, L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Whey Protein Natural Vanilla Flavor by NewtonEverett

Ask about any prescription or over-the-counter medication and we check it for interactions with Whey Protein Natural Vanilla Flavor by NewtonEverett — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Whey Protein Natural Vanilla Flavor by NewtonEverett

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 6 of its 6 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This powder has six active ingredients. L-glutamine, L-leucine, L-isoleucine, and L-valine are amino acids — building blocks your body uses to make protein and repair muscle.

Sodium is an electrolyte your body needs for nerve and muscle function. Stevia extract is a natural sweetener with no calories.

The product also contains several inactive ingredients (fillers and binders): whey protein isolate and concentrate in various forms, natural flavors, dairy whey, soy lecithin, and processing aids. These support texture and taste but aren't active components.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: build muscle with amino acids and protein.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, HIV/AIDS-related wasting, Malnutrition, Muscular dystrophy, Postoperative recovery — and 4 related terms.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for HIV/AIDS-related wasting (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Effective" for Critical illness (trauma), Postoperative recovery.
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance, Muscular dystrophy.

The data we hold shows effectiveness ratings for L-glutamine and stevia only. L-glutamine is rated effective for sickle cell disease and possibly effective for HIV/AIDS-related wasting, recovery after surgery, and critical illness from trauma.

Stevia has insufficient evidence to rate it for diabetes, high blood pressure, or weight loss — meaning the science isn't clear enough yet to say whether it works for those uses. We have no established effectiveness ratings for the other three amino acids in this product.

The evidence, ingredient by ingredient Glutamine Sodium Stevia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-glutamine is generally well tolerated in healthy adults but should be used only under medical supervision if you have kidney or liver disease. The most common side effects are gastrointestinal — belching, bloating, constipation, diarrhea, flatulence, nausea, and vomiting.

Headache and musculoskeletal pain have also been reported. People with bipolar disorder should be aware that mania and hypomania were reported in two patients taking high-dose glutamine, though this is rare.

Sodium is essential in small amounts but too much can raise blood pressure and strain your heart. Stevia extract appears well tolerated, though minor effects like abdominal bloating, dizziness, headache, nausea, and numbness can occur — most resolve within the first week.

Rare allergic reactions to stevia have been reported. For L-glutamine in pregnancy and breastfeeding, the data rates it as likely safe, but there isn't enough information on file to advise about the other ingredients during pregnancy or while nursing — talk with your pharmacist or doctor for personalized guidance.

Side effects, ingredient by ingredient Glutamine Sodium Stevia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Stevia, Glutamine, Sodium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications; diabetes medications; lithium.
  • For scale: 340 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications if you take any of these: anticonvulsants (seizure drugs) — L-glutamine may theoretically reduce their effect. Blood pressure medications — sodium and stevia may both interfere with how well they work.

Lithium — both sodium and stevia may alter lithium levels dangerously. Diabetes drugs — stevia may theoretically increase low-blood-sugar risk.

Also double-check if you take corticosteroids, didanosine (Videx), tolvaptan (Samsca), or sodium phosphate bowel preps.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This whey protein powder is a source of amino acids and electrolytes. If you take seizure medications, blood pressure drugs, lithium, diabetes medications, corticosteroids, or HIV drugs, you need to check your specific medications before using it — sodium and stevia can interact with several of these.

Otherwise, it's generally well tolerated; just watch for digestive side effects. Talk to your pharmacist if you have kidney or liver disease, bipolar disorder, or are pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Whey Protein Natural Vanilla Flavor, straight from the product label.

Brand NewtonEverett
Net contents 12.9 oz.; 366 Gram(s)
Market status On market
Date entered into DSLD Jun 25, 2014
DSLD ID 34730
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Whey Protein Natural Vanilla Flavor by NewtonEverett, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
21.5 Gram(s)
Maximum serving Sizes:
21.5 Gram(s)
Servings per container
17
IngredientAmount% DV
Calories80 {Calories}--
Total Carbohydrates3 Gram(s)1%
L-Glutamine100 mg--
Sugar1 Gram(s)--
Calories from Fat5 {Calories}--
Total Fat0.5 Gram(s)1%
Protein16 Gram(s)31%
Saturated Fat0 Gram(s)--
Sodium40 mg2%
Cholesterol10 mg3%
L-Leucine100 mg--
L-Isoleucine100 mg--
L-Valine100 mg--
Stevia extract50 mg--

Other ingredients: cross-flow micro-filtered Whey Protein isolate, Micro Filtered {Whey Protein Concentrate}, Ultra-Filtered Whey Protein Concentrate, Natural Flavors, sweet Dairy Whey, hydrolyzed Whey Protein concentrate, Ion-Exchanged Whey Protein Isolate, Soy Lecithin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

BUILD MUSCLE WITH 16G OF PROTEIN PER SERVING

PREMIUM QUALITY WHEY

Soy lecithin is a processing aid used for instantizing proteins.

WHEY PROTEIN has the highest value in providing branched-chain amino acids, which result in building and retaining muscle tissue. WHEY PROTEIN contains the perfect combination of overall amino acid makeup and in just the right concentrations for optimal performance in the body. It also plays a role as an antioxidant and helps support a healthy immune system. Most importantly, whey protein intake coupled with exercise will result in consistent muscle building.

Brand IP Statement(s)

Newton-Everett(R) WHEY PROTEIN provides the necessary building blocks to produce amino acids essential for building muscle.

FDA Statement of Identity

DIETARY SUPPLEMENT

Formula

Contains milk and soy (lecithin) ingredients.

PREMIUM QUALITY WHEY PROTEIN 17 SERVINGS 1g SUGAR 16g PROTEIN 80 CALORIES

Precautions

Allergen Information: Contains milk and soy (lecithin) ingredients.

! WARNING If you are pregnant, nursing, have any health condition or are taking any medications, consult your health care practitioner before using this product.

KEEP OUT OF REACH OF CHILDREN.

Do not use this product if the safety seal on bottle is broken.

Seals/Symbols

Q PREMIUM QUALITY POTENCY GUARANTEED

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested/Recommended/Usage/Directions

SUGGESTED USE: Blend one rounded scoop of WHEY PROTEIN with 6-8 oz (180-236ml) of milk, juice, or other favorite beverage. WHEY PROTEIN can also be blended with fruit, ice and other solid ingredients as desired.

Storage

Store in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Whey Protein Natural Vanilla Flavor by NewtonEverett label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Whey Protein Natural Vanilla Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Whey Protein Natural Vanilla Flavor by NewtonEverett

These are the 8 active ingredients this product is made of. Select any to open its full monograph.

Serving size21.5 Gram(s) Dosage formPowder Servings per container17 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Glutamine

Interacts with
50 drugs
100 mg per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions

Sugar

1 Gram(s) per serving

Protein

16 Gram(s) per serving

Sodium

Interacts with
205 drugs
40 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

L-Leucine

100 mg per serving

L-Isoleucine

100 mg per serving

L-Valine

100 mg per serving

Stevia extract

Interacts with
259 drugs
50 mg per serving

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regu...

Stevia extract monograph & interactions

Other (inactive) ingredients: Cross-flow micro-filtered Whey Protein isolate, Micro Filtered {Whey Protein Concentrate}, Ultra-Filtered Whey Protein Concentrate, Natural Flavors, Sweet Dairy Whey, Hydrolyzed Whey Protein concentrate, Ion-Exchanged Whey Protein Isolate, Soy Lecithin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Whey Protein Natural Vanilla Flavor by NewtonEverett Drug Interactions

Want to check YOUR meds against Whey Protein Natural Vanilla Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
340Drugs
254 Moderate 86 Minor

Ingredients driving the most interactions

Stevia extract 259
Sodium 205
L-Glutamine 50

Individual Drug Interactions

The ingredients in Whey Protein Natural Vanilla Flavor interact with 340 drugs. Click any drug to see the details.

3 of the 8 ingredients in Whey Protein Natural Vanilla Flavor interact with drugs. Each result below shows which ingredient is responsible. Stevia extract Sodium L-Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in Whey Protein Natural Vanilla Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Stevia extract3 drug types · 259 drugs

Lithium

Theoretically, stevia might decrease clearance and increase levels of lithium.
Animal research suggests that stevia extracts might have diuretic activity. Theoretically, increased reabsorption of lithium along with sodium might reduce excretion and increase levels of lithium.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Preliminary clinical research in patients with type 2 diabetes suggests that taking a single dose of stevia extract 1000 mg reduces postprandial blood glucose levels when taken with a meal. However, other clinical research in patients with type 1 or type 2 diabetes suggests that taking stevioside 250 mg three times daily does not significantly affect blood glucose levels or glycated hemoglobin (HbA1C) after three months of treatment.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Stevia extract and stevioside might lower blood pressure in patients with hypertension. However, other clinical research suggests that stevioside does not significantly lower blood pressure in patients with hypertension.

Likelihood Possible Evidence D
Stevia extract full monograph & interactions

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium full monograph & interactions

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Whey Protein Natural Vanilla Flavor, from the product label.

NewtonEverett

See all NewtonEverett products
Name
Newton-Everett
Pharmacist Counseling Corner

Whey Protein Natural Vanilla Flavor by NewtonEverett: Common Questions

Does Whey Protein Natural Vanilla Flavor by NewtonEverett interact with any medications?
Yes. Based on its ingredients, Whey Protein Natural Vanilla Flavor has a known interaction with 340 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Whey Protein Natural Vanilla Flavor contains 8 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is L-glutamine in this powder for?
L-glutamine is an amino acid (protein building block) that your body uses for muscle repair and immune function. Research shows it's effective for sickle cell disease and possibly helpful for recovery after surgery, wasting related to HIV/AIDS, and recovery from critical illness or trauma.
Will this give me digestive upset?
Possibly. L-glutamine can cause belching, bloating, constipation, diarrhea, flatulence, nausea, or vomiting in some people. Stevia may also cause abdominal bloating or nausea, though most mild effects resolve within the first week.
Is this safe to take if I have kidney disease?
L-glutamine requires medical supervision if you have kidney or liver disease. Check with your doctor or pharmacist before using this product.
Can I take this while pregnant?
L-glutamine is rated likely safe in pregnancy, but we don't have enough safety data on file for the other active ingredients. Talk with your pharmacist or doctor for personalized advice.
Why is there sodium in a protein powder?
Sodium is an electrolyte — your body needs it for nerve and muscle function. It's naturally present in whey protein and helps with flavor and function of the powder.
What does stevia extract do in this product?
Stevia is a natural, calorie-free sweetener. The research on whether stevia helps with diabetes, blood pressure, or weight loss is not yet conclusive.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Whey Protein Natural Vanilla Flavor is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Whey Protein Natural Vanilla Flavor label
Go deeper

The Full Monographs Behind Whey Protein Natural Vanilla Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph → Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Stevia

Interacts with 259 drugs

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regulators. Purified stevia extracts have a...

Read the full Stevia monograph →
Sources

Sources & How We Checked

Whey Protein Natural Vanilla Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 59 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Sodium 38 references
  1. Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
  2. Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
  3. Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
  4. Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol 2011;111(2):537-542. PubMed
  5. Frings-Meuthen P, Baecker N, Heer M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 2008;23(4):517-524. PubMed
  6. Alam S, Johnson AG. A meta-analysis of randomised controlled trials (RCT) among healthy normotensive and essential hypertensive elderly patients to determine the effect of high salt (NaCl) diet of blood pressure. J Hum Hypertens 1999;13(6):367-74.
  7. Boudville N, Ward S, Benaroia M, House AA. Increased sodium intake correlates with greater use of antihypertensive agents by subjects with chronic kidney disease. Am J Hypertens 2005;18(10):1300-5. PubMed
  8. Bennett WM. Drug interactions and consequences of sodium restriction. Am J Clin Nutr 1997;65(2 Suppl):678S-681S. PubMed
  9. Okusa MD, Crystal LJ. Clinical manifestations and management of acute lithium intoxication. Am J Med 1994;97(4):383-9. PubMed
  10. Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for water, potassium, sodium, chloride, and sulfate. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/openbook.php?record_id=10925. DOI
  11. D'Elia L, Rossi G, Ippolito R, Cappuccio FP, Strazzullo P. Habitual salt intake and risk of gastric cancer: a meta-analysis of prospective studies. Clin Nutr 2012;31(4):489-98. PubMed
  12. Goldsmith SR. Hyponatremia in heart failure: time for a trial. J Card Fail 2013;19(6):398-400. PubMed
  13. Willocks L, Brettle R, Keen J, Valentine C, Pinching AJ. Formulations of didanosine (ddI) and salt overload. Lancet 1992;339(8786):190.
  14. Chen L, Zhang Z, Chen W, Whelton PK, Appel LJ. Lower Sodium Intake and Risk of Headaches: Results From the Trial of Nonpharmacologic Interventions in the Elderly. Am J Public Health. 2016;106(7):1270-5. PubMed
  15. Cook NR, Appel LJ, Whelton PK. Lower levels of sodium intake and reduced cardiovascular risk. Circulation. 2014;129(9):981-9. PubMed
  16. Cook NR, Appel LJ, Whelton PK. Sodium Intake and All-Cause Mortality Over 20 Years in the Trials of Hypertension Prevention. J Am Coll Cardiol. 2016;68(15):1609-1617. PubMed
  17. Mente A, O'Donnell M, Rangarajan S, et al. Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies. Lancet. 2016;388(10043):465-75. PubMed
  18. Moosavian SP, Haghighatdoost F, Surkan PJ, Azadbakht L. Salt and obesity: a systematic review and meta-analysis of observational studies. Int J Food Sci Nutr. 2017;68(3):265-277. PubMed
  19. O'Donnell M, Mente A, Rangarajan S, et al. Urinary sodium and potassium excretion, mortality, and cardiovascular events. N Engl J Med. 2014;371(7):612-23. DOI
  20. Poggio R, Gutierrez L, Matta MG, Elorriaga N, Irazola V, Rubinstein A. Daily sodium consumption and CVD mortality in the general population: systematic review and meta-analysis of prospective studies. Public Health Nutr. 2015;18(4):695-704. PubMed
  21. Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad
  22. Mahtani KR, Heneghan C, Onakpoya I, et al. Reduced Salt Intake for Heart Failure: A Systematic Review. JAMA Intern Med. 2018 Dec 1;178(12):1693-1700. PubMed
  23. Yancy CW. Sodium Restriction in Heart Failure: Too Much Uncertainty-Do the Trials. JAMA Intern Med. 2018 Dec 1;178(12):1700-1701. PubMed
  24. He FJ, Campbell NRC, Ma Y, MacGregor GA, Cogswell ME, Cook NR. Errors in estimating usual sodium intake by the Kawasaki formula alter its relationship with mortality: implications for public health. Int J Epidemiol. 2018;47(6):1784-1795. PubMed
  25. Murthy K, Ondrey GJ, Malkani N, et al. THE EFFECTS OF HYPONATREMIA ON BONE DENSITY AND FRACTURES: A SYSTEMATIC REVIEW AND META-ANALYSIS. Endocr Pract. 2019;25(4):366-378. PubMed
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Stevia 10 references
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See these in context on the Stevia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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