Lenvatinib
Generic name: Pronounced as (len va' ti nib)
Medical Content Reviewed By HelloPharmacist Staff
Last Revised - 11/15/2021
On this page
- Why is this medication prescribed?
- How should this medicine be used?
- Other uses for this medicine
- What special precautions should I follow?
- What special dietary instructions should I follow?
- What should I do if I forget a dose?
- What side effects can this medication cause?
- What should I know about STORAGE and DISPOSAL of this medication?
- What should I do in case of OVERDOSE?
- What OTHER INFORMATION should I know?
- Drug interactions
Why is this medication prescribed?
Lenvatinib is used to treat a certain type of thyroid cancer that has returned or that has spread to other parts of the body and cannot be treated with radioactive iodine. Lenvatinib is also used along with everolimus (Afinitor, Zortress) to treat renal cell carcinoma (RCC, a type of cancer that begins in the kidney) in people who have previously received treatment with another chemotherapy medication. Lenvatinib is also used along with pembrolizumab (Keytruda) as an initial treatment for advanced renal cell carcinoma. Lenvatinib is also used to treat hepatocellular carcinoma (HCC; a type of liver cancer) that cannot be treated with surgery. Lenvatinib is also used along with pembrolizumab (Keytruda) to treat a certain type of cancer of the endometrium (lining of the uterus) that has spread to other parts of the body or worsened during or after treatment with chemotherapy medications or that cannot be treated with surgery or radiation therapy. Lenvatinib is in a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps stop the spread of cancer cells.
How should this medicine be used?
Lenvatinib comes as a capsule to take by mouth. It is usually taken once daily with or without food. Take lenvatinib at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take lenvatinib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Swallow the capsules whole; do not open, chew, or crush them.
If you are unable to swallow the capsules, put them into a small glass and add about one tablespoon of water or apple juice. Do not break or crush the capsules. Leave the capsules in the liquid for at least 10 minutes and then stir the contents for at least 3 minutes. Drink the mixture. After drinking the mixture, add another 1 tablespoon of water or apple juice to the glass. Swirl the contents a few times and swallow the mixture.
Your doctor may decrease your dose of lenvatinib or tell you to stop taking the medication for a time or permanently if you experience serious side effects. Be sure to talk to your doctor about how you are feeling during your treatment with lenvatinib.
The length of your treatment depends on how well you respond to the medication and the side effects you experience. Continue to take lenvatinib even if you feel well. Do not stop taking lenvatinib without talking to your doctor.
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking lenvatinib,
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tell your doctor and pharmacist if you are allergic to lenvatinib, any other medications, or any of the ingredients in lenvatinib capsules. Ask your pharmacist for a list of the ingredients.
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tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: certain medications for irregular heartbeat including amiodarone (Nexterone, Pacerone), disopyramide (Norpace), dofetilide (Tikosyn), dronedarone (Multaq), procainamide, quinidine (in Nuedexta), and sotalol (Betapace, Betapace AF, Sorine, Sotylize), ketoconazole, or rifampin (Rifadin,Rimactane). Also tell your doctor if you are taking or have taken alendronate (Binosto, Fosamax), denosumab (Prolia, Xgeva), ibandronate (Boniva), pamidronate, romosozumab-aqqg (Evenity), risedronate (Actonel, Atelvia), or zoledronic acid injection (Reclast, Zometa). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
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tell your doctor if you have or have ever had seizures; high blood pressure; a stroke; a heart attack; headaches; changes in vision, especially those due to blood clots; a fistula (abnormal connection between 2 organs inside your body or between an organ and the outside of your body); a tear in the wall of your stomach or intestine; QT interval prolongation (an irregular heart rhythm that can lead to fainting, loss of consciousness, seizures, or sudden death); heart failure; low levels of calcium, potassium, or magnesium in your blood; bleeding problems; problems with your mouth, teeth, or gums; thyroid problems; or heart, kidney, or liver disease. Also tell your doctor if you have severe diarrhea or vomiting or you think you may be dehydrated.
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you should know that lenvatinib may decrease fertility in men and women. However, you should not assume that you or your partner cannot become pregnant. Tell your doctor if you are pregnant or plan to become pregnant. You will need to have a pregnancy test before you begin treatment with lenvatinib. If you can become pregnant, you should use birth control during your treatment with lenvatinib and for at least 30 days after your final dose. If you become pregnant while you are taking lenvatinib, call your doctor immediately. Lenvatinib may harm the fetus.
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tell your doctor if you are breastfeeding or plan to breastfeed. You should not breastfeed while taking lenvatinib
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tell your doctor if you are planning to have any surgery, including dental surgery. Your doctor will probably tell you to stop your treatment with lenvatinib at least 7 days before your scheduled surgery because it can affect wound healing. Your doctor will tell you when to start taking lenvatinib again after your surgery.
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you should know that your blood pressure may increase during your treatment with lenvatinib. Your doctor will probably monitor your blood pressure during your treatment.
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you should know that lenvatinib may cause osteonecrosis of the jaw (ONJ, a serious condition of the jaw bone), especially if you have dental surgery or treatment while you are taking the medication. A dentist should examine your teeth and perform any needed treatments, including cleaning or fixing ill-fitted dentures, before you start to take lenvatinib. Be sure to brush your teeth and clean your mouth properly while you are taking lenvatinib. Tell your doctor or dentist if you have or have had mouth, teeth, or jaw pain; mouth sores or swelling; numbness or a feeling of heaviness in the jaw; or any loose teeth. Talk to your doctor before having any dental treatments while you are taking this medication. Your doctor will probably tell you to stop your treatment with lenvatinib at least 7 days before your scheduled dental procedure.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What should I do if I forget a dose?
If your next dose is due in 12 hours or more, take the missed dose as soon as you remember it. However, if the next dose will be taken in less than 12 hours, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
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Lenvatinib may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
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fatigue or tiredness
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rash, redness, itching, or peeling of skin on palms and sole(s) of the feet
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diarrhea
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nausea
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constipation
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heartburn
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decreased appetite
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weight loss
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change in ability to taste food
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cough
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hoarseness
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mouth sores
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dry mouth
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headache
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joint and muscle pain
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difficulty falling asleep or staying asleep
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hair loss
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fever
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burning during urination
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rash
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Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:
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shortness of breath or trouble breathing
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swelling of legs and ankles
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chest pain
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numbness or weakness of the face, arm, or leg on one side of your body
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pain in arms, back, neck, or jaw
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sudden, severe headache
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slow or difficult speech
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sudden changes in vision
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yellowing of the skin or eyes
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stomach pain
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dark (tea-colored) urine
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light-colored stools
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seizures
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weakness
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confusion
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severe and persistent nose bleeds
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bloody vomit
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black, tarry, or bloody stools
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coughing up blood or blood clots
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heavy menstrual bleeding
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vomiting, diarrhea, or signs of dehydration
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wounds that do not heal
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Lenvatinib may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
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If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
What should I know about STORAGE and DISPOSAL of this medication?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
What OTHER INFORMATION should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to lenvatinib.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Drug interactions
Drug | Interaction |
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Moxifloxacin | Moxifloxacin The risk or severity of QTc prolongation can be increased when Moxifloxacin is combined with Lenvatinib. |
Repaglinide | Repaglinide Lenvatinib may decrease the excretion rate of Repaglinide which could result in a higher serum level. |
Montelukast | Montelukast The metabolism of Montelukast can be decreased when combined with Lenvatinib. |
Leflunomide | Leflunomide The metabolism of Leflunomide can be decreased when combined with Lenvatinib. |
Delavirdine | Delavirdine The metabolism of Delavirdine can be decreased when combined with Lenvatinib. |
Nevirapine | Nevirapine The metabolism of Nevirapine can be decreased when combined with Lenvatinib. |
Atorvastatin | Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Lenvatinib. |
Dolasetron | Dolasetron The risk or severity of QTc prolongation can be increased when Dolasetron is combined with Lenvatinib. |
Aminophylline | Aminophylline The metabolism of Aminophylline can be increased when combined with Lenvatinib. |
Anagrelide | Anagrelide The risk or severity of QTc prolongation can be increased when Lenvatinib is combined with Anagrelide. |
Candesartan | Candesartan The metabolism of Candesartan can be decreased when combined with Lenvatinib. |
Cilostazol | Cilostazol The serum concentration of Cilostazol can be increased when it is combined with Lenvatinib. |
Clopidogrel | Clopidogrel The metabolism of Clopidogrel can be decreased when combined with Lenvatinib. |
Erythromycin and Sulfisoxazole | Erythromycin and Sulfisoxazole The risk or severity of liver damage can be increased when Erythromycin is combined with Lenvatinib. |
Estrogen and Progestin (Oral Contraceptives) | Estrogen and Progestin (Oral Contraceptives) The metabolism of Conjugated estrogens can be decreased when combined with Lenvatinib. |
Fenofibrate | Fenofibrate Lenvatinib may decrease the excretion rate of Fenofibrate which could result in a higher serum level. |
Paregoric | Paregoric The metabolism of Morphine can be decreased when combined with Lenvatinib. |
Penbutolol | Penbutolol The risk or severity of QTc prolongation can be increased when Acebutolol is combined with Lenvatinib. |
Ranitidine | Ranitidine The excretion of Ranitidine can be decreased when combined with Lenvatinib. |
Reserpine | Reserpine The serum concentration of Lenvatinib can be increased when it is combined with Reserpine. |
Sumatriptan | Sumatriptan The excretion of Sumatriptan can be decreased when combined with Lenvatinib. |
Tacrolimus | Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with Lenvatinib. |
Tizanidine | Tizanidine The metabolism of Tizanidine can be decreased when combined with Lenvatinib. |
Zolmitriptan | Zolmitriptan The metabolism of Zolmitriptan can be decreased when combined with Lenvatinib. |
Famotidine Injection | Famotidine Injection The risk or severity of QTc prolongation can be increased when Famotidine is combined with Lenvatinib. |
Fluconazole Injection | Fluconazole Injection The serum concentration of Lenvatinib can be increased when it is combined with Fluconazole. |
Foscarnet Injection | Foscarnet Injection The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Lenvatinib. |
Hydromorphone Injection | Hydromorphone Injection The metabolism of Hydromorphone can be decreased when combined with Lenvatinib. |
Levofloxacin Injection | Levofloxacin Injection The risk or severity of QTc prolongation can be increased when Lenvatinib is combined with Levofloxacin. |
Meperidine Injection | Meperidine Injection The metabolism of Meperidine can be increased when combined with Lenvatinib. |
Metoclopramide Injection | Metoclopramide Injection The risk or severity of QTc prolongation can be increased when Metoclopramide is combined with Lenvatinib. |
Metronidazole Injection | Metronidazole Injection The risk or severity of QTc prolongation can be increased when Metronidazole is combined with Lenvatinib. |
Morphine Injection | Morphine Injection The metabolism of Morphine can be decreased when combined with Lenvatinib. |
Zidovudine Injection | Zidovudine Injection The metabolism of Zidovudine can be decreased when combined with Lenvatinib. |
Altretamine | Altretamine The metabolism of Amphetamine can be decreased when combined with Lenvatinib. |
Cyclosporine | Cyclosporine The metabolism of Cyclosporine can be increased when combined with Lenvatinib. |
Ondansetron | Ondansetron The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Lenvatinib. |
Granisetron | Granisetron The risk or severity of QTc prolongation can be increased when Granisetron is combined with Lenvatinib. |
Torsemide | Torsemide The metabolism of Torasemide can be decreased when combined with Lenvatinib. |
Olanzapine | Olanzapine The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Lenvatinib. |
Alosetron | Alosetron The metabolism of Alosetron can be decreased when combined with Lenvatinib. |
Dofetilide | Dofetilide The metabolism of Dofetilide can be increased when combined with Lenvatinib. |
Hydroxychloroquine | Hydroxychloroquine The risk or severity of QTc prolongation can be increased when Hydroxychloroquine is combined with Lenvatinib. |
Meloxicam | Meloxicam The metabolism of Meloxicam can be decreased when combined with Lenvatinib. |
Pantoprazole | Pantoprazole Pantoprazole may decrease the excretion rate of Lenvatinib which could result in a higher serum level. |
Telmisartan | Telmisartan Lenvatinib may decrease the excretion rate of Telmisartan which could result in a higher serum level. |
Desloratadine | Desloratadine The risk or severity of QTc prolongation can be increased when Desloratadine is combined with Lenvatinib. |
Trimipramine | Trimipramine The metabolism of Trimipramine can be decreased when combined with Lenvatinib. |
Tenofovir | Tenofovir The serum concentration of Tenofovir can be increased when it is combined with Lenvatinib. |
Sirolimus | Sirolimus The metabolism of Sirolimus can be increased when combined with Lenvatinib. |
Epinephrine Injection | Epinephrine Injection The serum concentration of Epinephrine can be increased when it is combined with Lenvatinib. |
Escitalopram | Escitalopram The risk or severity of QTc prolongation can be increased when Lenvatinib is combined with Escitalopram. |
Olmesartan | Olmesartan The risk or severity of liver damage can be increased when Olmesartan is combined with Lenvatinib. |
Zonisamide | Zonisamide The serum concentration of Lenvatinib can be increased when it is combined with Zonisamide. |
Aripiprazole | Aripiprazole The metabolism of Aripiprazole can be increased when combined with Lenvatinib. |
Atomoxetine | Atomoxetine The metabolism of Atomoxetine can be decreased when combined with Lenvatinib. |
Ezetimibe | Ezetimibe Lenvatinib may decrease the excretion rate of Ezetimibe which could result in a higher serum level. |
Teriparatide Injection | Teriparatide Injection The therapeutic efficacy of Teriparatide can be decreased when used in combination with Lenvatinib. |
Atazanavir | Atazanavir The metabolism of Atazanavir can be increased when combined with Lenvatinib. |
Almotriptan | Almotriptan The metabolism of Almotriptan can be decreased when combined with Lenvatinib. |
Eletriptan | Eletriptan The metabolism of Eletriptan can be decreased when combined with Lenvatinib. |
Mefloquine | Mefloquine The risk or severity of QTc prolongation can be increased when Mefloquine is combined with Lenvatinib. |
Rosuvastatin | Rosuvastatin Lenvatinib may decrease the excretion rate of Rosuvastatin which could result in a higher serum level. |
Vardenafil | Vardenafil The metabolism of Vardenafil can be decreased when combined with Lenvatinib. |
Alfuzosin | Alfuzosin The metabolism of Alfuzosin can be decreased when combined with Lenvatinib. |
Memantine | Memantine The serum concentration of Memantine can be increased when it is combined with Lenvatinib. |
Tegaserod | Tegaserod The metabolism of Tegaserod can be decreased when combined with Lenvatinib. |
Frovatriptan | Frovatriptan The metabolism of Frovatriptan can be decreased when combined with Lenvatinib. |
Gemifloxacin | Gemifloxacin The risk or severity of QTc prolongation can be increased when Gemifloxacin is combined with Lenvatinib. |
Progesterone | Progesterone The risk or severity of liver damage can be increased when Progesterone is combined with Lenvatinib. |
Apomorphine Injection | Apomorphine Injection The risk or severity of QTc prolongation can be increased when Apomorphine is combined with Lenvatinib. |
Darbepoetin Alfa Injection | Darbepoetin Alfa Injection The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Lenvatinib. |
Protriptyline | Protriptyline The risk or severity of QTc prolongation can be increased when Protriptyline is combined with Lenvatinib. |
Duloxetine | Duloxetine The metabolism of Duloxetine can be decreased when combined with Lenvatinib. |
Norethindrone | Norethindrone The metabolism of Norethisterone can be increased when combined with Lenvatinib. |
Tinidazole | Tinidazole Lenvatinib may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
Bosentan | Bosentan The risk or severity of liver damage can be increased when Bosentan is combined with Lenvatinib. |
Cefditoren | Cefditoren The excretion of Cefdinir can be decreased when combined with Lenvatinib. |
Cinacalcet | Cinacalcet The metabolism of Cinacalcet can be decreased when combined with Lenvatinib. |
Erlotinib | Erlotinib The serum concentration of Erlotinib can be decreased when it is combined with Lenvatinib. |
Eszopiclone | Eszopiclone The serum concentration of Eszopiclone can be decreased when it is combined with Lenvatinib. |
Solifenacin | Solifenacin The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Lenvatinib. |
Voriconazole | Voriconazole The metabolism of Voriconazole can be decreased when combined with Lenvatinib. |
Dextroamphetamine | Dextroamphetamine The metabolism of Amphetamine can be decreased when combined with Lenvatinib. |
Entecavir | Entecavir The metabolism of Entecavir can be decreased when combined with Lenvatinib. |
Ibandronate | Ibandronate The risk or severity of QTc prolongation can be increased when Ibandronate is combined with Lenvatinib. |
Ramelteon | Ramelteon The metabolism of Ramelteon can be decreased when combined with Lenvatinib. |
Darifenacin | Darifenacin The metabolism of Darifenacin can be decreased when combined with Lenvatinib. |
Fentanyl | Fentanyl The metabolism of Fentanyl can be decreased when combined with Lenvatinib. |
Pregabalin | Pregabalin The risk or severity of QTc prolongation can be increased when Pregabalin is combined with Lenvatinib. |
Tipranavir | Tipranavir The serum concentration of Lenvatinib can be increased when it is combined with Tipranavir. |
Felbamate | Felbamate The risk or severity of QTc prolongation can be increased when Felbamate is combined with Lenvatinib. |
Ranolazine | Ranolazine The metabolism of Lenvatinib can be increased when combined with Ranolazine. |
Rasagiline | Rasagiline The metabolism of Rasagiline can be decreased when combined with Lenvatinib. |
Imatinib | Imatinib The risk or severity of QTc prolongation can be increased when Lenvatinib is combined with Imatinib. |
Sitagliptin | Sitagliptin The metabolism of Sitagliptin can be decreased when combined with Lenvatinib. |
Varenicline | Varenicline The excretion of Varenicline can be decreased when combined with Lenvatinib. |
Gefitinib | Gefitinib Gefitinib may decrease the excretion rate of Lenvatinib which could result in a higher serum level. |
Albuterol | Albuterol The risk or severity of QTc prolongation can be increased when Salbutamol is combined with Lenvatinib. |
Paliperidone | Paliperidone The risk or severity of QTc prolongation can be increased when Lenvatinib is combined with Paliperidone. |
Bortezomib | Bortezomib The metabolism of Lenvatinib can be increased when combined with Bortezomib. |
Clofarabine Injection | Clofarabine Injection The serum concentration of Clofarabine can be increased when it is combined with Lenvatinib. |
Oxaliplatin Injection | Oxaliplatin Injection The serum concentration of Oxaliplatin can be increased when it is combined with Lenvatinib. |
Posaconazole | Posaconazole The serum concentration of Lenvatinib can be increased when it is combined with Posaconazole. |
Primaquine | Primaquine The metabolism of Primaquine can be decreased when combined with Lenvatinib. |
Pemetrexed Injection | Pemetrexed Injection The excretion of Pemetrexed can be decreased when combined with Lenvatinib. |
Dimenhydrinate | Dimenhydrinate The risk or severity of QTc prolongation can be increased when Dimenhydrinate is combined with Lenvatinib. |
Lisdexamfetamine | Lisdexamfetamine The metabolism of Lisdexamfetamine can be decreased when combined with Lenvatinib. |
Retapamulin | Retapamulin The metabolism of Retapamulin can be decreased when combined with Lenvatinib. |
Vorinostat | Vorinostat The risk or severity of QTc prolongation can be increased when Vorinostat is combined with Lenvatinib. |
Sorafenib | Sorafenib The metabolism of Sorafenib can be increased when combined with Lenvatinib. |
Sunitinib | Sunitinib The metabolism of Lenvatinib can be increased when combined with Sunitinib. |
Dronabinol | Dronabinol Dronabinol may decrease the excretion rate of Lenvatinib which could result in a higher serum level. |
Lapatinib | Lapatinib The metabolism of Lapatinib can be decreased when combined with Lenvatinib. |
Levocetirizine | Levocetirizine The risk or severity of QTc prolongation can be increased when Levocetirizine is combined with Lenvatinib. |
Dasatinib | Dasatinib The metabolism of Dasatinib can be increased when combined with Lenvatinib. |
Mexiletine | Mexiletine The metabolism of Mexiletine can be decreased when combined with Lenvatinib. |
Temsirolimus | Temsirolimus The metabolism of Temsirolimus can be increased when combined with Lenvatinib. |
Nilotinib | Nilotinib The metabolism of Nilotinib can be increased when combined with Lenvatinib. |
Toremifene | Toremifene The risk or severity of QTc prolongation can be increased when Lenvatinib is combined with Toremifene. |
Bexarotene | Bexarotene The metabolism of Bexarotene can be decreased when combined with Lenvatinib. |
Budesonide | Budesonide Lenvatinib may decrease the excretion rate of Budesonide which could result in a higher serum level. |
Doripenem Injection | Doripenem Injection The excretion of Doripenem can be decreased when combined with Lenvatinib. |
Etravirine | Etravirine The metabolism of Etravirine can be decreased when combined with Lenvatinib. |
Arsenic Trioxide Injection | Arsenic Trioxide Injection The risk or severity of QTc prolongation can be increased when Lenvatinib is combined with Arsenic trioxide. |
Cevimeline | Cevimeline The metabolism of Cevimeline can be decreased when combined with Lenvatinib. |
Nebivolol | Nebivolol The metabolism of Nebivolol can be decreased when combined with Lenvatinib. |
Tretinoin | Tretinoin The metabolism of Tretinoin can be decreased when combined with Lenvatinib. |
Bendamustine Injection | Bendamustine Injection The metabolism of Bendamustine can be decreased when combined with Lenvatinib. |
Leucovorin Injection | Leucovorin Injection The excretion of Leucovorin can be decreased when combined with Lenvatinib. |
Flecainide | Flecainide The metabolism of Flecainide can be decreased when combined with Lenvatinib. |
Ixabepilone Injection | Ixabepilone Injection The metabolism of Ixabepilone can be increased when combined with Lenvatinib. |
Irinotecan Injection | Irinotecan Injection The metabolism of Irinotecan can be increased when combined with Lenvatinib. |
Praziquantel | Praziquantel The metabolism of Praziquantel can be decreased when combined with Lenvatinib. |
Rufinamide | Rufinamide The metabolism of Lenvatinib can be increased when combined with Rufinamide. |
Silodosin | Silodosin The serum concentration of Lenvatinib can be increased when it is combined with Silodosin. |
Midazolam | Midazolam The serum concentration of Midazolam can be increased when it is combined with Lenvatinib. |
Eltrombopag | Eltrombopag Eltrombopag may decrease the excretion rate of Lenvatinib which could result in a higher serum level. |
Milnacipran | Milnacipran The metabolism of Milnacipran can be increased when combined with Lenvatinib. |
Dexlansoprazole | Dexlansoprazole The metabolism of Dexlansoprazole can be decreased when combined with Lenvatinib. |
Fesoterodine | Fesoterodine The metabolism of Fesoterodine can be decreased when combined with Lenvatinib. |
Degarelix Injection | Degarelix Injection The risk or severity of QTc prolongation can be increased when Degarelix is combined with Lenvatinib. |
Betaxolol | Betaxolol The risk or severity of QTc prolongation can be increased when Betaxolol is combined with Lenvatinib. |
Iloperidone | Iloperidone The metabolism of Iloperidone can be decreased when combined with Lenvatinib. |
Prasugrel | Prasugrel The metabolism of Prasugrel can be decreased when combined with Lenvatinib. |
Lacosamide | Lacosamide The metabolism of Lacosamide can be decreased when combined with Lenvatinib. |
Everolimus | Everolimus The metabolism of Everolimus can be increased when combined with Lenvatinib. |
Tolvaptan (low blood sodium) | Tolvaptan (low blood sodium) The metabolism of Lenvatinib can be increased when combined with Tolvaptan. |
Dronedarone | Dronedarone The metabolism of Dronedarone can be increased when combined with Lenvatinib. |
Palonosetron Injection | Palonosetron Injection The metabolism of Palonosetron can be decreased when combined with Lenvatinib. |
Saxagliptin | Saxagliptin The excretion of Saxagliptin can be decreased when combined with Lenvatinib. |
Telavancin Injection | Telavancin Injection The risk or severity of QTc prolongation can be increased when Telavancin is combined with Lenvatinib. |
Romidepsin Injection | Romidepsin Injection The metabolism of Romidepsin can be increased when combined with Lenvatinib. |
Tapentadol | Tapentadol The metabolism of Tapentadol can be decreased when combined with Lenvatinib. |
Topotecan | Topotecan The serum concentration of Topotecan can be increased when it is combined with Lenvatinib. |
Pazopanib | Pazopanib The metabolism of Pazopanib can be increased when combined with Lenvatinib. |
Asenapine | Asenapine The risk or severity of QTc prolongation can be increased when Lenvatinib is combined with Asenapine. |
Pitavastatin | Pitavastatin Lenvatinib may decrease the excretion rate of Pitavastatin which could result in a higher serum level. |
Albendazole | Albendazole The metabolism of Albendazole can be increased when combined with Lenvatinib. |
Ulipristal | Ulipristal The metabolism of Ulipristal can be increased when combined with Lenvatinib. |
Levonorgestrel | Levonorgestrel The metabolism of Levonorgestrel can be increased when combined with Lenvatinib. |
Oxymorphone | Oxymorphone The metabolism of Oxymorphone can be decreased when combined with Lenvatinib. |
Dalfampridine | Dalfampridine The serum concentration of Dalfampridine can be increased when it is combined with Lenvatinib. |
Eribulin Injection | Eribulin Injection The risk or severity of QTc prolongation can be increased when Eribulin is combined with Lenvatinib. |
Cabazitaxel Injection | Cabazitaxel Injection The metabolism of Lenvatinib can be increased when combined with Cabazitaxel. |
Lurasidone | Lurasidone The risk or severity of QTc prolongation can be increased when Lurasidone is combined with Lenvatinib. |
Acetaminophen Injection | Acetaminophen Injection The serum concentration of Acetaminophen can be increased when it is combined with Lenvatinib. |
Vilazodone | Vilazodone The metabolism of Vilazodone can be decreased when combined with Lenvatinib. |
Terbutaline Injection | Terbutaline Injection The risk or severity of QTc prolongation can be increased when Terbutaline is combined with Lenvatinib. |
Busulfan Injection | Busulfan Injection The metabolism of Busulfan can be increased when combined with Lenvatinib. |
Roflumilast | Roflumilast The metabolism of Roflumilast can be increased when combined with Lenvatinib. |
Linagliptin | Linagliptin The serum concentration of Lenvatinib can be increased when it is combined with Linagliptin. |
Rilpivirine | Rilpivirine Rilpivirine may decrease the excretion rate of Lenvatinib which could result in a higher serum level. |
Telaprevir | Telaprevir The serum concentration of Lenvatinib can be increased when it is combined with Glecaprevir. |
Potassium Iodide | Potassium Iodide The therapeutic efficacy of Potassium Iodide can be decreased when used in combination with Lenvatinib. |
Cyclophosphamide Injection | Cyclophosphamide Injection The metabolism of Cyclophosphamide can be increased when combined with Lenvatinib. |
Triptorelin Injection | Triptorelin Injection The risk or severity of QTc prolongation can be increased when Triptorelin is combined with Lenvatinib. |
Rivaroxaban | Rivaroxaban The serum concentration of Lenvatinib can be increased when it is combined with Rivaroxaban. |
Ticagrelor | Ticagrelor The serum concentration of Lenvatinib can be increased when it is combined with Ticagrelor. |
Brentuximab Vedotin Injection | Brentuximab Vedotin Injection The metabolism of Brentuximab vedotin can be increased when combined with Lenvatinib. |
Ruxolitinib | Ruxolitinib The metabolism of Ruxolitinib can be increased when combined with Lenvatinib. |
Vandetanib | Vandetanib The metabolism of Vandetanib can be increased when combined with Lenvatinib. |
Clobazam | Clobazam The metabolism of Clobazam can be decreased when combined with Lenvatinib. |
Vemurafenib | Vemurafenib The serum concentration of Lenvatinib can be increased when it is combined with Vemurafenib. |
Vismodegib | Vismodegib Vismodegib may decrease the excretion rate of Lenvatinib which could result in a higher serum level. |
Ivacaftor | Ivacaftor The serum concentration of Lenvatinib can be increased when it is combined with Ivacaftor. |
Axitinib | Axitinib The metabolism of Axitinib can be increased when combined with Lenvatinib. |
Crizotinib | Crizotinib The metabolism of Lenvatinib can be increased when combined with Crizotinib. |
Cabergoline | Cabergoline The metabolism of Cabergoline can be increased when combined with Lenvatinib. |
Ambrisentan | Ambrisentan The serum concentration of Lenvatinib can be increased when it is combined with Ambrisentan. |
Carfilzomib Injection | Carfilzomib Injection The serum concentration of Lenvatinib can be increased when it is combined with Carfilzomib. |
Enzalutamide | Enzalutamide The serum concentration of Lenvatinib can be increased when it is combined with Enzalutamide. |
Mirabegron | Mirabegron The risk or severity of QTc prolongation can be increased when Mirabegron is combined with Lenvatinib. |
Regorafenib | Regorafenib The metabolism of Lenvatinib can be increased when combined with Regorafenib. |
Bosutinib | Bosutinib The metabolism of Bosutinib can be increased when combined with Lenvatinib. |
Teriflunomide | Teriflunomide Teriflunomide may decrease the excretion rate of Lenvatinib which could result in a higher serum level. |
Cabozantinib (thyroid cancer) | Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Lenvatinib. |
Bedaquiline | Bedaquiline The risk or severity of QTc prolongation can be increased when Bedaquiline is combined with Lenvatinib. |
Tofacitinib | Tofacitinib The metabolism of Tofacitinib can be decreased when combined with Lenvatinib. |
Alogliptin | Alogliptin The metabolism of Alogliptin can be decreased when combined with Lenvatinib. |
Ponatinib | Ponatinib The metabolism of Lenvatinib can be increased when combined with Ponatinib. |
Pomalidomide | Pomalidomide The metabolism of Pomalidomide can be increased when combined with Lenvatinib. |
Ado-trastuzumab Emtansine Injection | Ado-trastuzumab Emtansine Injection The metabolism of Lenvatinib can be increased when combined with Trastuzumab emtansine. |
Apixaban | Apixaban The metabolism of Apixaban can be decreased when combined with Lenvatinib. |
Canagliflozin | Canagliflozin The serum concentration of Lenvatinib can be increased when it is combined with Canagliflozin. |
Dabrafenib | Dabrafenib The metabolism of Lenvatinib can be increased when combined with Dabrafenib. |
Ospemifene | Ospemifene The metabolism of Ospemifene can be decreased when combined with Lenvatinib. |
Dolutegravir | Dolutegravir The serum concentration of Lenvatinib can be increased when it is combined with Dolutegravir. |
Afatinib | Afatinib The serum concentration of Lenvatinib can be increased when it is combined with Afatinib. |
Levomilnacipran | Levomilnacipran The metabolism of Levomilnacipran can be increased when combined with Lenvatinib. |
Vortioxetine | Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Lenvatinib. |
Perampanel | Perampanel The metabolism of Perampanel can be increased when combined with Lenvatinib. |
Ibrutinib | Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Lenvatinib. |
Lomitapide | Lomitapide The metabolism of Lomitapide can be decreased when combined with Lenvatinib. |
Ketorolac Injection | Ketorolac Injection The metabolism of Ketorolac can be decreased when combined with Lenvatinib. |
Simeprevir | Simeprevir The risk or severity of liver damage can be increased when Simeprevir is combined with Lenvatinib. |
Sofosbuvir | Sofosbuvir The serum concentration of Lenvatinib can be increased when it is combined with Sofosbuvir. |
Dapagliflozin | Dapagliflozin The metabolism of Dapagliflozin can be decreased when combined with Lenvatinib. |
Apremilast | Apremilast The metabolism of Lenvatinib can be decreased when combined with Apremilast. |
Ceritinib | Ceritinib The metabolism of Lenvatinib can be increased when combined with Ceritinib. |
Belinostat Injection | Belinostat Injection The serum concentration of Lenvatinib can be increased when it is combined with Belinostat. |
Idelalisib | Idelalisib The metabolism of Idelalisib can be increased when combined with Lenvatinib. |
Testosterone Injection | Testosterone Injection The metabolism of Testosterone can be decreased when combined with Lenvatinib. |
Vorapaxar | Vorapaxar The serum concentration of Lenvatinib can be increased when it is combined with Vorapaxar. |
Hydrocodone | Hydrocodone The metabolism of Hydrocodone can be decreased when combined with Lenvatinib. |
Suvorexant | Suvorexant The serum concentration of Lenvatinib can be increased when it is combined with Suvorexant. |
Edoxaban | Edoxaban The serum concentration of Lenvatinib can be increased when it is combined with Edoxaban. |
Olaparib | Olaparib The metabolism of Lenvatinib can be increased when combined with Olaparib. |
Caspofungin Injection | Caspofungin Injection The excretion of Caspofungin can be decreased when combined with Lenvatinib. |
Methamphetamine | Methamphetamine The metabolism of Metamfetamine can be decreased when combined with Lenvatinib. |
Tasimelteon | Tasimelteon The metabolism of Tasimelteon can be decreased when combined with Lenvatinib. |
Riociguat | Riociguat The metabolism of Riociguat can be decreased when combined with Lenvatinib. |
Pirfenidone | Pirfenidone The metabolism of Pirfenidone can be decreased when combined with Lenvatinib. |
Nintedanib | Nintedanib The serum concentration of Nintedanib can be increased when it is combined with Lenvatinib. |
Risperidone Injection | Risperidone Injection The metabolism of Risperidone can be decreased when combined with Lenvatinib. |
Palbociclib | Palbociclib The metabolism of Lenvatinib can be increased when combined with Palbociclib. |
Panobinostat | Panobinostat The metabolism of Lenvatinib can be increased when combined with Panobinostat. |
Haloperidol Injection | Haloperidol Injection The risk or severity of QTc prolongation can be increased when Lenvatinib is combined with Haloperidol. |
Ivabradine | Ivabradine Ivabradine may increase the QTc-prolonging activities of Lenvatinib. |
Isavuconazonium Injection | Isavuconazonium Injection The serum concentration of Lenvatinib can be increased when it is combined with Isavuconazonium. |
Sonidegib | Sonidegib The metabolism of Sonidegib can be increased when combined with Lenvatinib. |
Flibanserin | Flibanserin The serum concentration of Lenvatinib can be increased when it is combined with Flibanserin. |
Rolapitant | Rolapitant The serum concentration of Lenvatinib can be increased when it is combined with Rolapitant. |
Daclatasvir | Daclatasvir The serum concentration of Lenvatinib can be increased when it is combined with Daclatasvir. |
Brexpiprazole | Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Lenvatinib. |
Ziprasidone Injection | Ziprasidone Injection The risk or severity of QTc prolongation can be increased when Lenvatinib is combined with Ziprasidone. |
Cariprazine | Cariprazine The metabolism of Cariprazine can be decreased when combined with Lenvatinib. |
Eluxadoline | Eluxadoline The serum concentration of Eluxadoline can be increased when it is combined with Lenvatinib. |
Cobimetinib | Cobimetinib The metabolism of Lenvatinib can be increased when combined with Cobimetinib. |
Trabectedin Injection | Trabectedin Injection The metabolism of Trabectedin can be increased when combined with Lenvatinib. |
Osimertinib | Osimertinib The metabolism of Osimertinib can be increased when combined with Lenvatinib. |
Alectinib | Alectinib The metabolism of Lenvatinib can be increased when combined with Alectinib. |
Ixazomib | Ixazomib The metabolism of Ixazomib can be increased when combined with Lenvatinib. |
Lesinurad | Lesinurad The metabolism of Lesinurad can be decreased when combined with Lenvatinib. |
Dexamethasone Injection | Dexamethasone Injection The excretion of Dexamethasone can be decreased when combined with Lenvatinib. |
Brivaracetam Injection | Brivaracetam Injection The metabolism of Brivaracetam can be decreased when combined with Lenvatinib. |
Venetoclax | Venetoclax The metabolism of Lenvatinib can be increased when combined with Venetoclax. |
Cobicistat | Cobicistat The serum concentration of Lenvatinib can be increased when it is combined with Cobicistat. |
Selexipag | Selexipag The metabolism of Selexipag can be decreased when combined with Lenvatinib. |
Obeticholic Acid | Obeticholic Acid The risk or severity of adverse effects can be increased when Lenvatinib is combined with Obeticholic acid. |
Diphenhydramine Injection | Diphenhydramine Injection The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Lenvatinib. |
Rucaparib | Rucaparib The serum concentration of Lenvatinib can be increased when it is combined with Rucaparib. |
Ribociclib | Ribociclib The risk or severity of QTc prolongation can be increased when Lenvatinib is combined with Ribociclib. |
Parathyroid Hormone Injection | Parathyroid Hormone Injection The therapeutic efficacy of Parathyroid hormone can be decreased when used in combination with Lenvatinib. |
Brigatinib | Brigatinib The metabolism of Lenvatinib can be increased when combined with Brigatinib. |
Doxepin (Insomnia) | Doxepin (Insomnia) The metabolism of Doxepin can be decreased when combined with Lenvatinib. |
Deutetrabenazine | Deutetrabenazine The risk or severity of QTc prolongation can be increased when Lenvatinib is combined with Deutetrabenazine. |
Valbenazine | Valbenazine The metabolism of Valbenazine can be decreased when combined with Lenvatinib. |
Safinamide | Safinamide Safinamide may decrease the excretion rate of Lenvatinib which could result in a higher serum level. |
Edaravone Injection | Edaravone Injection The excretion of Edaravone can be decreased when combined with Lenvatinib. |
Midostaurin | Midostaurin The metabolism of Midostaurin can be increased when combined with Lenvatinib. |
Neratinib | Neratinib The metabolism of Lenvatinib can be increased when combined with Neratinib. |
Abaloparatide Injection | Abaloparatide Injection The therapeutic efficacy of Abaloparatide can be decreased when used in combination with Lenvatinib. |
Enasidenib | Enasidenib The metabolism of Lenvatinib can be increased when combined with Enasidenib. |
Inotuzumab Ozogamicin Injection | Inotuzumab Ozogamicin Injection The serum concentration of Lenvatinib can be increased when it is combined with Inotuzumab ozogamicin. |
Aprepitant/Fosaprepitant Injection | Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be increased when combined with Lenvatinib. |
Copanlisib Injection | Copanlisib Injection The metabolism of Copanlisib can be increased when combined with Lenvatinib. |
Delafloxacin | Delafloxacin The risk or severity of QTc prolongation can be increased when Delafloxacin is combined with Lenvatinib. |
Abemaciclib | Abemaciclib The metabolism of Lenvatinib can be increased when combined with Abemaciclib. |
Betrixaban | Betrixaban The serum concentration of Betrixaban can be increased when it is combined with Lenvatinib. |
Acalabrutinib | Acalabrutinib The metabolism of Acalabrutinib can be increased when combined with Lenvatinib. |
Letermovir | Letermovir The risk or severity of liver damage can be increased when Lenvatinib is combined with Letermovir. |
Tetrabenazine | Tetrabenazine The risk or severity of QTc prolongation can be increased when Lenvatinib is combined with Tetrabenazine. |
Ertugliflozin | Ertugliflozin The serum concentration of Ertugliflozin can be increased when it is combined with Lenvatinib. |
Buprenorphine Injection | Buprenorphine Injection Buprenorphine may decrease the excretion rate of Lenvatinib which could result in a higher serum level. |
Apalutamide | Apalutamide The serum concentration of Lenvatinib can be decreased when it is combined with Apalutamide. |
Penicillamine | Penicillamine The excretion of Penicillamine can be decreased when combined with Lenvatinib. |
Fostamatinib | Fostamatinib Fostamatinib may decrease the excretion rate of Lenvatinib which could result in a higher serum level. |
Avatrombopag | Avatrombopag Avatrombopag may decrease the excretion rate of Lenvatinib which could result in a higher serum level. |
Baricitinib | Baricitinib The metabolism of Lenvatinib can be increased when combined with Baricitinib. |
Lofexidine | Lofexidine The metabolism of Lofexidine can be decreased when combined with Lenvatinib. |
Eliglustat | Eliglustat The metabolism of Eliglustat can be decreased when combined with Lenvatinib. |
Encorafenib | Encorafenib The metabolism of Encorafenib can be decreased when combined with Lenvatinib. |
Binimetinib | Binimetinib The metabolism of Binimetinib can be decreased when combined with Lenvatinib. |
Ivosidenib | Ivosidenib The metabolism of Lenvatinib can be increased when combined with Ivosidenib. |
Lusutrombopag | Lusutrombopag The serum concentration of Lusutrombopag can be increased when it is combined with Lenvatinib. |
Elagolix | Elagolix The metabolism of Elagolix can be decreased when combined with Lenvatinib. |
Tafenoquine | Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Lenvatinib. |
Cannabidiol | Cannabidiol Cannabidiol may decrease the excretion rate of Lenvatinib which could result in a higher serum level. |
Dacomitinib | Dacomitinib The metabolism of Lenvatinib can be increased when combined with Dacomitinib. |
Duvelisib | Duvelisib The serum concentration of Duvelisib can be increased when it is combined with Lenvatinib. |
Omadacycline | Omadacycline The serum concentration of Omadacycline can be increased when it is combined with Lenvatinib. |
Sarecycline | Sarecycline The serum concentration of Lenvatinib can be increased when it is combined with Sarecycline. |
Stiripentol | Stiripentol The metabolism of Stiripentol can be decreased when combined with Lenvatinib. |
Talazoparib | Talazoparib The serum concentration of Talazoparib can be increased when it is combined with Lenvatinib. |
Gilteritinib | Gilteritinib Gilteritinib may decrease the excretion rate of Lenvatinib which could result in a higher serum level. |
Glasdegib | Glasdegib The risk or severity of QTc prolongation can be increased when Lenvatinib is combined with Glasdegib. |
Lorlatinib | Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Lenvatinib. |
Larotrectinib | Larotrectinib The serum concentration of Larotrectinib can be increased when it is combined with Lenvatinib. |
Methoxy Polyethylene Glycol-Epoetin Beta Injection | Methoxy Polyethylene Glycol-Epoetin Beta Injection The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Lenvatinib. |
Paclitaxel (with albumin) Injection | Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be increased when combined with Lenvatinib. |
Rifamycin | Rifamycin The serum concentration of Lenvatinib can be increased when it is combined with Rifamycin. |
Prucalopride | Prucalopride The metabolism of Prucalopride can be decreased when combined with Lenvatinib. |
Siponimod | Siponimod The metabolism of Siponimod can be increased when combined with Lenvatinib. |
Acyclovir Ophthalmic | Acyclovir Ophthalmic The metabolism of Acyclovir can be decreased when combined with Lenvatinib. |
Erdafitinib | Erdafitinib The serum concentration of Lenvatinib can be increased when it is combined with Erdafitinib. |
Esomeprazole Injection | Esomeprazole Injection The metabolism of Esomeprazole can be decreased when combined with Lenvatinib. |
Alpelisib | Alpelisib The metabolism of Alpelisib can be increased when combined with Lenvatinib. |
Solriamfetol | Solriamfetol The serum concentration of Solriamfetol can be increased when it is combined with Lenvatinib. |
Darolutamide | Darolutamide The serum concentration of Lenvatinib can be increased when it is combined with Darolutamide. |
Triclabendazole | Triclabendazole The risk or severity of QTc prolongation can be increased when Triclabendazole is combined with Lenvatinib. |
Entrectinib | Entrectinib The risk or severity of QTc prolongation can be increased when Lenvatinib is combined with Entrectinib. |
Pexidartinib | Pexidartinib The metabolism of Pexidartinib can be increased when combined with Lenvatinib. |
Istradefylline | Istradefylline The metabolism of Istradefylline can be decreased when combined with Lenvatinib. |
Pitolisant | Pitolisant The serum concentration of Lenvatinib can be decreased when it is combined with Pitolisant. |
Fedratinib | Fedratinib Fedratinib may decrease the excretion rate of Lenvatinib which could result in a higher serum level. |
Lefamulin | Lefamulin Lefamulin may increase the QTc-prolonging activities of Lenvatinib. |
Phenytoin Injection | Phenytoin Injection The metabolism of Phenytoin can be decreased when combined with Lenvatinib. |
Fosphenytoin Injection | Fosphenytoin Injection The metabolism of Fosphenytoin can be decreased when combined with Lenvatinib. |
Enfortumab vedotin-ejfv Injection | Enfortumab vedotin-ejfv Injection The serum concentration of Enfortumab vedotin can be increased when it is combined with Lenvatinib. |
Zanubrutinib | Zanubrutinib The metabolism of Zanubrutinib can be increased when combined with Lenvatinib. |
Voxelotor | Voxelotor The serum concentration of Voxelotor can be increased when it is combined with Lenvatinib. |
Avapritinib | Avapritinib The metabolism of Avapritinib can be decreased when combined with Lenvatinib. |
Lumateperone | Lumateperone The serum concentration of Lumateperone can be decreased when it is combined with Lenvatinib. |
Lasmiditan | Lasmiditan The serum concentration of Lenvatinib can be increased when it is combined with Lasmiditan. |
Ubrogepant | Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Lenvatinib. |
Tazemetostat | Tazemetostat The serum concentration of Tazemetostat can be increased when it is combined with Lenvatinib. |
Cenobamate | Cenobamate The serum concentration of Cenobamate can be decreased when it is combined with Lenvatinib. |
Ozanimod | Ozanimod The metabolism of Ozanimod can be decreased when combined with Lenvatinib. |
Selumetinib | Selumetinib The metabolism of Selumetinib can be decreased when combined with Lenvatinib. |
Rimegepant | Rimegepant The metabolism of Rimegepant can be increased when combined with Lenvatinib. |
Tucatinib | Tucatinib Lenvatinib may decrease the excretion rate of Tucatinib which could result in a higher serum level. |
Remdesivir Injection | Remdesivir Injection The serum concentration of Remdesivir can be increased when it is combined with Lenvatinib. |
Ripretinib | Ripretinib Ripretinib may decrease the excretion rate of Lenvatinib which could result in a higher serum level. |
Selpercatinib | Selpercatinib The serum concentration of Selpercatinib can be decreased when it is combined with Lenvatinib. |
Capmatinib | Capmatinib The serum concentration of Capmatinib can be decreased when it is combined with Lenvatinib. |
Lemborexant | Lemborexant The serum concentration of Lemborexant can be decreased when it is combined with Lenvatinib. |
Fostemsavir | Fostemsavir The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Lenvatinib. |
Octreotide | Octreotide The risk or severity of QTc prolongation can be increased when Octreotide is combined with Lenvatinib. |
Belantamab Mafodotin-blmf Injection | Belantamab Mafodotin-blmf Injection Lenvatinib may decrease the excretion rate of Belantamab mafodotin which could result in a higher serum level. |
Pralsetinib | Pralsetinib Pralsetinib may decrease the excretion rate of Lenvatinib which could result in a higher serum level. |
Satralizumab-mwge Injection | Satralizumab-mwge Injection The serum concentration of Lenvatinib can be decreased when it is combined with Satralizumab. |
Relugolix | Relugolix The risk or severity of QTc prolongation can be increased when Relugolix is combined with Lenvatinib. |
Progestin-Only (drospirenone) Oral Contraceptives | Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Drospirenone can be increased when combined with Lenvatinib. |
Theophylline | Theophylline The metabolism of Theophylline can be increased when combined with Lenvatinib. |
Indomethacin | Indomethacin Lenvatinib may decrease the excretion rate of Indomethacin which could result in a higher serum level. |
Mefenamic Acid | Mefenamic Acid The metabolism of Mefenamic acid can be decreased when combined with Lenvatinib. |
Naproxen | Naproxen Lenvatinib may decrease the excretion rate of Naproxen which could result in a higher serum level. |
Trazodone | Trazodone The risk or severity of QTc prolongation can be increased when Trazodone is combined with Lenvatinib. |
Phenobarbital | Phenobarbital The metabolism of Phenobarbital can be decreased when combined with Lenvatinib. |
Methotrexate Injection | Methotrexate Injection The metabolism of Methotrexate can be increased when combined with Lenvatinib. |
Primidone | Primidone The metabolism of Primidone can be decreased when combined with Lenvatinib. |
Methsuximide | Methsuximide The risk or severity of QTc prolongation can be increased when Methsuximide is combined with Lenvatinib. |
Chlorpromazine | Chlorpromazine The risk or severity of liver damage can be increased when Chlorpromazine is combined with Lenvatinib. |
Diazepam | Diazepam The metabolism of Diazepam can be decreased when combined with Lenvatinib. |
Lorazepam | Lorazepam The metabolism of Lorazepam can be increased when combined with Lenvatinib. |
Carmustine | Carmustine The metabolism of Carmustine can be decreased when combined with Lenvatinib. |
Amantadine | Amantadine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Lenvatinib. |
Codeine | Codeine The metabolism of Codeine can be decreased when combined with Lenvatinib. |
Tetracycline | Tetracycline The excretion of Tetracycline can be decreased when combined with Lenvatinib. |
Prochlorperazine | Prochlorperazine The metabolism of Prochlorperazine can be decreased when combined with Lenvatinib. |
Thioridazine | Thioridazine The risk or severity of QTc prolongation can be increased when Lenvatinib is combined with Thioridazine. |
Trifluoperazine | Trifluoperazine The metabolism of Trifluoperazine can be decreased when combined with Lenvatinib. |
Dapsone | Dapsone The metabolism of Dapsone can be decreased when combined with Lenvatinib. |
Sulfadiazine | Sulfadiazine The metabolism of Sulfadiazine can be decreased when combined with Lenvatinib. |
Oxycodone | Oxycodone The metabolism of Oxycodone can be decreased when combined with Lenvatinib. |
Methadone | Methadone The metabolism of Methadone can be decreased when combined with Lenvatinib. |
Benztropine | Benztropine The risk or severity of QTc prolongation can be increased when Benzatropine is combined with Lenvatinib. |
Maprotiline | Maprotiline The risk or severity of QTc prolongation can be increased when Maprotiline is combined with Lenvatinib. |
Ibuprofen | Ibuprofen The metabolism of Ibuprofen can be decreased when combined with Lenvatinib. |
Orphenadrine | Orphenadrine The risk or severity of QTc prolongation can be increased when Orphenadrine is combined with Lenvatinib. |
Perphenazine | Perphenazine The metabolism of Perphenazine can be decreased when combined with Lenvatinib. |
Azathioprine | Azathioprine The metabolism of Azathioprine can be decreased when combined with Lenvatinib. |
Phentermine | Phentermine The metabolism of Phentermine can be increased when combined with Lenvatinib. |
Amoxapine | Amoxapine The metabolism of Lenvatinib can be decreased when combined with Amoxapine. |
Sulfasalazine | Sulfasalazine Sulfasalazine may decrease the excretion rate of Lenvatinib which could result in a higher serum level. |
Hydrocortisone | Hydrocortisone The excretion of Hydrocortisone can be decreased when combined with Lenvatinib. |
Doxorubicin | Doxorubicin The metabolism of Doxorubicin can be increased when combined with Lenvatinib. |
Dactinomycin | Dactinomycin The serum concentration of Lenvatinib can be increased when it is combined with Dactinomycin. |
Carbamazepine | Carbamazepine The metabolism of Carbamazepine can be increased when combined with Lenvatinib. |
Clonidine | Clonidine The metabolism of Clonidine can be increased when combined with Lenvatinib. |
Prazosin | Prazosin The serum concentration of Prazosin can be increased when it is combined with Lenvatinib. |
Cimetidine | Cimetidine The excretion of Cimetidine can be decreased when combined with Lenvatinib. |
Warfarin | Warfarin The metabolism of Warfarin can be increased when combined with Lenvatinib. |
Clonazepam | Clonazepam The metabolism of Clonazepam can be increased when combined with Lenvatinib. |
Loperamide | Loperamide The serum concentration of Lenvatinib can be increased when it is combined with Loperamide. |
Promethazine | Promethazine The metabolism of Promethazine can be decreased when combined with Lenvatinib. |
Daunorubicin | Daunorubicin Lenvatinib may decrease the excretion rate of Daunorubicin which could result in a higher serum level. |
Nitrofurantoin | Nitrofurantoin Lenvatinib may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level. |
Digoxin | Digoxin Lenvatinib may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Loxapine | Loxapine The serum concentration of Lenvatinib can be increased when it is combined with Loxapine. |
Chloroquine | Chloroquine The metabolism of Chloroquine can be decreased when combined with Lenvatinib. |
Quinine | Quinine The risk or severity of QTc prolongation can be increased when Lenvatinib is combined with Quinine. |
Ethosuximide | Ethosuximide The risk or severity of QTc prolongation can be increased when Ethosuximide is combined with Lenvatinib. |
Triamterene | Triamterene The metabolism of Triamterene can be decreased when combined with Lenvatinib. |
Sulfinpyrazone | Sulfinpyrazone Lenvatinib may decrease the excretion rate of Sulfinpyrazone which could result in a higher serum level. |
Isosorbide | Isosorbide The metabolism of Isosorbide can be increased when combined with Lenvatinib. |
Clindamycin Injection | Clindamycin Injection The metabolism of Clindamycin can be increased when combined with Lenvatinib. |
Desipramine | Desipramine The metabolism of Lenvatinib can be decreased when combined with Desipramine. |
Amitriptyline | Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Lenvatinib. |
Imipramine | Imipramine The metabolism of Imipramine can be decreased when combined with Lenvatinib. |
Quinidine | Quinidine The metabolism of Quinidine can be increased when combined with Lenvatinib. |
Procainamide | Procainamide The metabolism of Procainamide can be decreased when combined with Lenvatinib. |
Rifampin | Rifampin The risk or severity of liver damage can be increased when Rifampicin is combined with Lenvatinib. |
Disopyramide | Disopyramide The risk or severity of QTc prolongation can be increased when Lenvatinib is combined with Disopyramide. |
Valproic Acid | Valproic Acid The risk or severity of QTc prolongation can be increased when Lenvatinib is combined with Valproic acid. |
Tamoxifen | Tamoxifen The metabolism of Lenvatinib can be increased when combined with Tamoxifen. |
Levothyroxine | Levothyroxine The therapeutic efficacy of Levothyroxine can be decreased when used in combination with Lenvatinib. |
Liothyronine | Liothyronine The therapeutic efficacy of Liothyronine can be decreased when used in combination with Lenvatinib. |
Methimazole | Methimazole The therapeutic efficacy of Methimazole can be decreased when used in combination with Lenvatinib. |
Propylthiouracil | Propylthiouracil The therapeutic efficacy of Propylthiouracil can be decreased when used in combination with Lenvatinib. |
Chlorpropamide | Chlorpropamide The metabolism of Chlorpropamide can be decreased when combined with Lenvatinib. |
Tolbutamide | Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Lenvatinib. |
Tolazamide | Tolazamide The metabolism of Tolazamide can be decreased when combined with Lenvatinib. |
Dextromethorphan | Dextromethorphan The metabolism of Dextromethorphan can be decreased when combined with Lenvatinib. |
Dinoprostone | Dinoprostone The excretion of Dinoprostone can be decreased when combined with Lenvatinib. |
Cyclobenzaprine | Cyclobenzaprine The metabolism of Cyclobenzaprine can be decreased when combined with Lenvatinib. |
Doxylamine | Doxylamine The risk or severity of QTc prolongation can be increased when Doxylamine is combined with Lenvatinib. |
Cyproheptadine | Cyproheptadine The risk or severity of QTc prolongation can be increased when Cyproheptadine is combined with Lenvatinib. |
Clemastine | Clemastine The risk or severity of QTc prolongation can be increased when Lenvatinib is combined with Clemastine. |
Chlorpheniramine | Chlorpheniramine The risk or severity of QTc prolongation can be increased when Chlorpheniramine is combined with Lenvatinib. |
Brompheniramine | Brompheniramine The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Lenvatinib. |
Meclizine | Meclizine The metabolism of Meclizine can be decreased when combined with Lenvatinib. |
Hydrochlorothiazide | Hydrochlorothiazide The risk or severity of QTc prolongation can be increased when Hydrochlorothiazide is combined with Lenvatinib. |
Chlorzoxazone | Chlorzoxazone The metabolism of Chlorzoxazone can be decreased when combined with Lenvatinib. |
Carisoprodol | Carisoprodol The metabolism of Carisoprodol can be decreased when combined with Lenvatinib. |
Disulfiram | Disulfiram Lenvatinib may decrease the excretion rate of Disulfiram which could result in a higher serum level. |
Propranolol (Cardiovascular) | Propranolol (Cardiovascular) The serum concentration of Propranolol can be increased when it is combined with Lenvatinib. |
Nortriptyline | Nortriptyline The metabolism of Lenvatinib can be increased when combined with Nortriptyline. |
Spironolactone | Spironolactone Lenvatinib may decrease the excretion rate of Spironolactone which could result in a higher serum level. |
Mercaptopurine | Mercaptopurine The excretion of Mercaptopurine can be decreased when combined with Lenvatinib. |
Nadolol | Nadolol The metabolism of Nadolol can be decreased when combined with Lenvatinib. |
Allopurinol | Allopurinol The excretion of Allopurinol can be decreased when combined with Lenvatinib. |
Oxytocin Injection | Oxytocin Injection The risk or severity of QTc prolongation can be increased when Oxytocin is combined with Lenvatinib. |
Clomiphene | Clomiphene The serum concentration of Lenvatinib can be increased when it is combined with Clomifene. |
Papaverine | Papaverine The risk or severity of QTc prolongation can be increased when Papaverine is combined with Lenvatinib. |
Fluorouracil Injection | Fluorouracil Injection The metabolism of Fluorouracil can be decreased when combined with Lenvatinib. |
Colchicine | Colchicine The metabolism of Colchicine can be decreased when combined with Lenvatinib. |
Cefaclor | Cefaclor Lenvatinib may decrease the excretion rate of Cefaclor which could result in a higher serum level. |
Cefazolin Injection | Cefazolin Injection The excretion of Cefazolin can be decreased when combined with Lenvatinib. |
Cephalexin | Cephalexin The excretion of Cephalexin can be decreased when combined with Lenvatinib. |
Dacarbazine | Dacarbazine The metabolism of Dacarbazine can be decreased when combined with Lenvatinib. |
Calcitonin Salmon Injection | Calcitonin Salmon Injection The therapeutic efficacy of Salmon calcitonin can be decreased when used in combination with Lenvatinib. |
Ketoconazole | Ketoconazole The serum concentration of Lenvatinib can be increased when it is combined with Ketoconazole. |
Thiotepa Injection | Thiotepa Injection The metabolism of Thiotepa can be increased when combined with Lenvatinib. |
Vincristine Injection | Vincristine Injection The metabolism of Vincristine can be increased when combined with Lenvatinib. |
Captopril | Captopril The excretion of Captopril can be decreased when combined with Lenvatinib. |
Dipyridamole | Dipyridamole Lenvatinib may decrease the excretion rate of Dipyridamole which could result in a higher serum level. |
Vinblastine | Vinblastine The metabolism of Lenvatinib can be increased when combined with Vinblastine. |
Metoprolol | Metoprolol The metabolism of Metoprolol can be decreased when combined with Lenvatinib. |
Hydroxyzine | Hydroxyzine The risk or severity of QTc prolongation can be increased when Hydroxyzine is combined with Lenvatinib. |
Thiothixene | Thiothixene The risk or severity of QTc prolongation can be increased when Thiothixene is combined with Lenvatinib. |
Aspirin | Aspirin The metabolism of Acetylsalicylic acid can be decreased when combined with Lenvatinib. |
Alprazolam | Alprazolam The metabolism of Alprazolam can be decreased when combined with Lenvatinib. |
Hyoscyamine | Hyoscyamine The risk or severity of QTc prolongation can be increased when Hyoscyamine is combined with Lenvatinib. |
Trimethoprim | Trimethoprim The metabolism of Trimethoprim can be decreased when combined with Lenvatinib. |
Diltiazem | Diltiazem The metabolism of Diltiazem can be decreased when combined with Lenvatinib. |
Nifedipine | Nifedipine Lenvatinib may decrease the excretion rate of Nifedipine which could result in a higher serum level. |
Timolol | Timolol The metabolism of Timolol can be decreased when combined with Lenvatinib. |
Verapamil | Verapamil The metabolism of Verapamil can be decreased when combined with Lenvatinib. |
Atenolol | Atenolol Lenvatinib may decrease the excretion rate of Atenolol which could result in a higher serum level. |
Pindolol | Pindolol The metabolism of Pindolol can be decreased when combined with Lenvatinib. |
Cisplatin Injection | Cisplatin Injection The serum concentration of Cisplatin can be increased when it is combined with Lenvatinib. |
Piroxicam | Piroxicam The metabolism of Piroxicam can be decreased when combined with Lenvatinib. |
Bumetanide | Bumetanide The excretion of Bumetanide can be decreased when combined with Lenvatinib. |
Etoposide | Etoposide The metabolism of Lenvatinib can be increased when combined with Etoposide. |
Glyburide | Glyburide The risk or severity of liver damage can be increased when Glyburide is combined with Lenvatinib. |
Glipizide | Glipizide Lenvatinib may decrease the excretion rate of Glipizide which could result in a higher serum level. |
Indapamide | Indapamide The risk or severity of QTc prolongation can be increased when Indapamide is combined with Lenvatinib. |
Pentoxifylline | Pentoxifylline The metabolism of Pentoxifylline can be decreased when combined with Lenvatinib. |
Pentamidine Injection | Pentamidine Injection The metabolism of Pentamidine can be decreased when combined with Lenvatinib. |
Labetalol | Labetalol The metabolism of Labetalol can be decreased when combined with Lenvatinib. |
Leuprolide Injection | Leuprolide Injection The risk or severity of QTc prolongation can be increased when Leuprolide is combined with Lenvatinib. |
Guanabenz | Guanabenz The metabolism of Guanabenz can be decreased when combined with Lenvatinib. |
Dipivefrin Ophthalmic | Dipivefrin Ophthalmic The excretion of Adefovir dipivoxil can be decreased when combined with Lenvatinib. |
Pimozide | Pimozide The metabolism of Pimozide can be increased when combined with Lenvatinib. |
Enalapril | Enalapril The excretion of Enalapril can be decreased when combined with Lenvatinib. |
Flurbiprofen | Flurbiprofen The metabolism of Flurbiprofen can be decreased when combined with Lenvatinib. |
Amiodarone | Amiodarone The metabolism of Lenvatinib can be increased when combined with Amiodarone. |
Buspirone | Buspirone The metabolism of Buspirone can be decreased when combined with Lenvatinib. |
Lovastatin | Lovastatin The metabolism of Lovastatin can be decreased when combined with Lenvatinib. |
Ciprofloxacin | Ciprofloxacin The risk or severity of QTc prolongation can be increased when Ciprofloxacin is combined with Lenvatinib. |
Diclofenac | Diclofenac Lenvatinib may decrease the excretion rate of Diclofenac which could result in a higher serum level. |
Fluoxetine | Fluoxetine The risk or severity of QTc prolongation can be increased when Lenvatinib is combined with Fluoxetine. |
Nimodipine | Nimodipine The risk or severity of QTc prolongation can be increased when Nimodipine is combined with Lenvatinib. |
Clozapine | Clozapine The risk or severity of QTc prolongation can be increased when Clozapine is combined with Lenvatinib. |
Idarubicin | Idarubicin The metabolism of Idarubicin can be decreased when combined with Lenvatinib. |
Ofloxacin | Ofloxacin Lenvatinib may decrease the excretion rate of Ofloxacin which could result in a higher serum level. |
Didanosine | Didanosine The excretion of Didanosine can be decreased when combined with Lenvatinib. |
Clarithromycin | Clarithromycin The serum concentration of Lenvatinib can be increased when it is combined with Clarithromycin. |
Etodolac | Etodolac The metabolism of Etodolac can be decreased when combined with Lenvatinib. |
Felodipine | Felodipine Lenvatinib may decrease the excretion rate of Felodipine which could result in a higher serum level. |
Nabumetone | Nabumetone The metabolism of Nabumetone can be decreased when combined with Lenvatinib. |
Pravastatin | Pravastatin Lenvatinib may decrease the excretion rate of Pravastatin which could result in a higher serum level. |
Quinapril | Quinapril The excretion of Quinapril can be decreased when combined with Lenvatinib. |
Simvastatin | Simvastatin The serum concentration of Lenvatinib can be increased when it is combined with Simvastatin. |
Epoetin Alfa, Injection | Epoetin Alfa, Injection The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Lenvatinib. |
Teniposide Injection | Teniposide Injection The metabolism of Teniposide can be increased when combined with Lenvatinib. |
Itraconazole | Itraconazole The serum concentration of Lenvatinib can be increased when it is combined with Itraconazole. |
Sotalol | Sotalol The metabolism of Sotalol can be decreased when combined with Lenvatinib. |
Bisoprolol | Bisoprolol The serum concentration of Lenvatinib can be increased when it is combined with Bisoprolol. |
Zolpidem | Zolpidem The metabolism of Zolpidem can be decreased when combined with Lenvatinib. |
Doxazosin | Doxazosin The metabolism of Doxazosin can be increased when combined with Lenvatinib. |
Isradipine | Isradipine Lenvatinib may decrease the excretion rate of Isradipine which could result in a higher serum level. |
Omeprazole | Omeprazole Omeprazole may decrease the excretion rate of Lenvatinib which could result in a higher serum level. |
Cisapride | Cisapride The risk or severity of QTc prolongation can be increased when Lenvatinib is combined with Cisapride. |
Fluvastatin | Fluvastatin The metabolism of Fluvastatin can be decreased when combined with Lenvatinib. |
Venlafaxine | Venlafaxine The metabolism of Lenvatinib can be decreased when combined with Venlafaxine. |
Stavudine | Stavudine The excretion of Stavudine can be decreased when combined with Lenvatinib. |
Famciclovir | Famciclovir The metabolism of Famciclovir can be increased when combined with Lenvatinib. |
Fluvoxamine | Fluvoxamine Lenvatinib may decrease the excretion rate of Fluvoxamine which could result in a higher serum level. |
Nefazodone | Nefazodone The metabolism of Nefazodone can be decreased when combined with Lenvatinib. |
Lamotrigine | Lamotrigine The risk or severity of QTc prolongation can be increased when Lamotrigine is combined with Lenvatinib. |
Losartan | Losartan Lenvatinib may decrease the excretion rate of Losartan which could result in a higher serum level. |
Valacyclovir | Valacyclovir The excretion of Valaciclovir can be decreased when combined with Lenvatinib. |
Tramadol | Tramadol The metabolism of Tramadol can be decreased when combined with Lenvatinib. |
Vinorelbine Injection | Vinorelbine Injection The metabolism of Vinorelbine can be increased when combined with Lenvatinib. |
Moexipril | Moexipril The risk or severity of QTc prolongation can be increased when Moexipril is combined with Lenvatinib. |
Lansoprazole | Lansoprazole Lansoprazole may decrease the excretion rate of Lenvatinib which could result in a higher serum level. |
Alprostadil Urogenital | Alprostadil Urogenital The excretion of Alprostadil can be decreased when combined with Lenvatinib. |
Ifosfamide Injection | Ifosfamide Injection The metabolism of Ifosfamide can be increased when combined with Lenvatinib. |
Nicardipine | Nicardipine Lenvatinib may decrease the excretion rate of Nicardipine which could result in a higher serum level. |
Bupropion | Bupropion The serum concentration of Bupropion can be increased when it is combined with Lenvatinib. |
Ticlopidine | Ticlopidine The metabolism of Ticlopidine can be decreased when combined with Lenvatinib. |
Saquinavir | Saquinavir Saquinavir may decrease the excretion rate of Lenvatinib which could result in a higher serum level. |
Metformin | Metformin The serum concentration of Metformin can be increased when it is combined with Lenvatinib. |
Lamivudine | Lamivudine The serum concentration of Lamivudine can be increased when it is combined with Lenvatinib. |
Riluzole | Riluzole The metabolism of Riluzole can be decreased when combined with Lenvatinib. |
Glimepiride | Glimepiride Lenvatinib may decrease the excretion rate of Glimepiride which could result in a higher serum level. |
Anastrozole | Anastrozole The metabolism of Anastrozole can be decreased when combined with Lenvatinib. |
Gemcitabine Injection | Gemcitabine Injection The serum concentration of Gemcitabine can be increased when it is combined with Lenvatinib. |
Indinavir | Indinavir Lenvatinib may decrease the excretion rate of Indinavir which could result in a higher serum level. |
Ritonavir | Ritonavir The serum concentration of Lenvatinib can be increased when it is combined with Ritonavir. |
Docetaxel Injection | Docetaxel Injection The metabolism of Docetaxel can be increased when combined with Lenvatinib. |
Cidofovir Injection | Cidofovir Injection The excretion of Cidofovir can be decreased when combined with Lenvatinib. |
Clomipramine | Clomipramine The metabolism of Clomipramine can be increased when combined with Lenvatinib. |
Zafirlukast | Zafirlukast The metabolism of Zafirlukast can be decreased when combined with Lenvatinib. |
Mirtazapine | Mirtazapine The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Lenvatinib. |
Zileuton | Zileuton The metabolism of Zileuton can be decreased when combined with Lenvatinib. |
Valsartan | Valsartan The metabolism of Valsartan can be decreased when combined with Lenvatinib. |
Pramipexole | Pramipexole The serum concentration of Pramipexole can be increased when it is combined with Lenvatinib. |
Donepezil | Donepezil The metabolism of Donepezil can be decreased when combined with Lenvatinib. |
Nelfinavir | Nelfinavir Nelfinavir may decrease the excretion rate of Lenvatinib which could result in a higher serum level. |
Fexofenadine | Fexofenadine The serum concentration of Lenvatinib can be increased when it is combined with Fexofenadine. |
Azithromycin | Azithromycin The metabolism of Azithromycin can be increased when combined with Lenvatinib. |
Loratadine | Loratadine Lenvatinib may decrease the excretion rate of Loratadine which could result in a higher serum level. |
Carvedilol | Carvedilol The serum concentration of Lenvatinib can be increased when it is combined with Carvedilol. |
Flutamide | Flutamide The metabolism of Flutamide can be decreased when combined with Lenvatinib. |
Selegiline | Selegiline The metabolism of Selegiline can be decreased when combined with Lenvatinib. |
Bicalutamide | Bicalutamide The metabolism of Bicalutamide can be increased when combined with Lenvatinib. |
Sertraline | Sertraline The metabolism of Sertraline can be decreased when combined with Lenvatinib. |
Propafenone | Propafenone The serum concentration of Lenvatinib can be increased when it is combined with Propafenone. |
Raloxifene | Raloxifene The excretion of Raloxifene can be decreased when combined with Lenvatinib. |
Irbesartan | Irbesartan The metabolism of Irbesartan can be decreased when combined with Lenvatinib. |
Tamsulosin | Tamsulosin The metabolism of Tamsulosin can be decreased when combined with Lenvatinib. |
Ropinirole | Ropinirole The risk or severity of adverse effects can be increased when Lenvatinib is combined with Ropinirole. |
Quetiapine | Quetiapine The metabolism of Quetiapine can be decreased when combined with Lenvatinib. |
Cetirizine | Cetirizine The risk or severity of QTc prolongation can be increased when Cetirizine is combined with Lenvatinib. |
Paroxetine | Paroxetine The metabolism of Paroxetine can be decreased when combined with Lenvatinib. |
Citalopram | Citalopram Lenvatinib may increase the QTc-prolonging activities of Citalopram. |
Capecitabine | Capecitabine The metabolism of Capecitabine can be decreased when combined with Lenvatinib. |
Efavirenz | Efavirenz The metabolism of Efavirenz can be decreased when combined with Lenvatinib. |
Sildenafil | Sildenafil The serum concentration of Lenvatinib can be increased when it is combined with Sildenafil. |
Pioglitazone | Pioglitazone The metabolism of Pioglitazone can be decreased when combined with Lenvatinib. |
Celecoxib | Celecoxib The risk or severity of liver damage can be increased when Lenvatinib is combined with Celecoxib. |
Rosiglitazone | Rosiglitazone Lenvatinib may decrease the excretion rate of Rosiglitazone which could result in a higher serum level. |
Tolterodine | Tolterodine The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Lenvatinib. |
Thalidomide | Thalidomide The metabolism of Thalidomide can be decreased when combined with Lenvatinib. |
Oseltamivir | Oseltamivir The excretion of Oseltamivir can be decreased when combined with Lenvatinib. |
Nateglinide | Nateglinide The metabolism of Nateglinide can be decreased when combined with Lenvatinib. |
Galantamine | Galantamine The risk or severity of QTc prolongation can be increased when Galantamine is combined with Lenvatinib. |
Rabeprazole | Rabeprazole Rabeprazole may decrease the excretion rate of Lenvatinib which could result in a higher serum level. |
Terbinafine | Terbinafine The metabolism of Terbinafine can be decreased when combined with Lenvatinib. |
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