Acepromazine

17 interactions 2 explained in plain English
Also sold as: PROMACE
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Acepromazine Acetaminophen And Codeine Capital® & Codeine Explained An increased risk of respiratory and CNS depression Details Acepromazine Buprenorphine Belbuca Explained An increased risk of respiratory depression and CNS depression Details Acepromazine Butorphanol Injection Butorphic Increased risk of respiratory and CNS depression Details Acepromazine Butorphanol Nasal Spray Stadol® NS Increased risk of respiratory and CNS depression Details Acepromazine Cetirizine Injection Aller-Tec Increased risk of CNS depression Details Acepromazine Cetirizine Ophthalmic Zerviate Increased risk of CNS depression Details Acepromazine Diazepam Nasal Spray Valtoco Increased risk of CNS depression Details Acepromazine Diazepam Rectal Diastat Increased risk of CNS depression Details Acepromazine Esketamine Nasal Spray Spravato Increased risk of sedation Details Acepromazine Fentanyl Transdermal Patch Duragesic® Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Acepromazine Hydromorphone Injection Dilaudid Increased risk of respiratory and CNS depression Details Acepromazine Hydromorphone Rectal available generically Increased risk of respiratory and CNS depression Details Acepromazine Lacosamide Injection Motpoly An increased risk of CNS depression Details Acepromazine Metoclopramide Injection Gimoti Increased risk of CNS depression Details Acepromazine Metoclopramide Nasal Spray Gimoti Increased risk of CNS depression Details Acepromazine Morphine Injection Astramorph® PF Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Acepromazine Nalbuphine Injection Nubain® Increased risk of respiratory and CNS depression Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.