Drug & supplement interaction

Arrach + Minocycline

Minocycline brand names: Vectrin, Dynacin, Minocin, Minocin IV, Solodyn, and others.

Moderate Interaction
Medically reviewed by · Updated September 2026
The bottom line Moderate

Arrach has a moderate interaction with Minocycline. Theoretically, concomitant use of arrach can increase risk of adverse effects, as unspecified Chenopodium species are associated with photosensitivity.

Read the full interaction report
SeverityModerate
LikelihoodPossible
EvidenceD
What do Severity, Likelihood & Evidence mean?
Know someone taking this? Share
Facebook Post Reddit Email
On this page
Interaction report

Arrach and Minocycline

Here is the interaction we found between these two, with the evidence behind it.

Moderate

PHOTOSENSITIZING DRUGS

Why this applies to Minocycline

Minocycline falls under PHOTOSENSITIZING DRUGS — the group Arrach interacts with.

Theoretically, concomitant use of arrach can increase risk of adverse effects, as unspecified Chenopodium species are associated with photosensitivity.
Severity Moderate Likelihood Possible Evidence D

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the simple version: minocycline already makes your skin more sensitive to sunlight. That means you can sunburn faster than usual, and some people get rashes or a worse reaction on exposed skin. Some plants in the goosefoot family (which Arrach belongs to) have also been linked to sun sensitivity. So the worry is that pairing the two could stack that effect and make your skin react even more easily.

I want to be honest about how thin this evidence is. This is a theoretical concern based on the plant's family, not real-world reports with minocycline specifically. The bigger, well-proven sun risk here comes from the minocycline itself, so use sunscreen and cover up regardless. Before adding any Arrach product, please run it by your pharmacist or doctor.

Contact Dr. Brian directly if you have additional questions on this interaction
References
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Arrach Also Interacts With Other Medications

Arrach has 334 moderate known drug interactions in our database — the Minocycline one above is one of them. If you take anything else, check it against the full list below.

Moderate 334 No known interaction 2,496 (incl. Minocycline)
Taking anything else?

Check Another of Your Medications Against Arrach

Covers the 2,830 medications we’ve checked against Arrach. Pick one to open its full report.

From our Q&A

Questions About Arrach or Minocycline

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Arrach or Minocycline, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Minocycline

This page covers Arrach only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Minocycline page lists 331 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Asarabacca (major), Beer (major), Danshen (major) and Oleander (major).

By severity: 9 major · 290 moderate · 32 minor.

From our pharmacist’s overview on the Minocycline page

“This is one of the longer interaction lists I review, and with minocycline it earns real care rather than a shrug. Most entries pair this tetracycline antibiotic, taken for acne and other infections, with supplements that raise bleeding risk, and a second sizable group, beer and wine included, can add strain on the liver.”

Reviewed by 2 · Jul 18, 2026

Open the Minocycline interaction page

How much people look this up

Where Arrach and Minocycline Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Arrach
Top half

#495 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Minocycline
Top half

#862 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Arrach

What is Arrach?

Arrach
  • Painful menstruation
  • Nervous complaints
  • Digestive upset
  • Wound care
  • Insect repellent

Arrach (Chenopodium vulvaria) is a strong-smelling European herb that has been used in traditional folk medicine, mainly for menstrual and nervous complaints. There is very little modern scientific evidence to show that it works or is safe, so it is not recommended, especially during pregnancy or breastfeeding. Talk to your pharmacist or doctor before using any herbal product.

Read the full Arrach monograph & all interactions
Medication

About Minocycline

What Is Minocycline Used For?

Brand names: Vectrin, Dynacin, Minocin, Minocin IV, Solodyn, Acnamino MR, Minocin MR, Sebomin MR, Aknemin, Arestin Miscrosperes, Amzeeq, Zilxi

Oral and intravenous minocycline products treat many serious bacterial infections, including Rocky Mountain spotted fever, respiratory tract infections, sexually transmitted infections such as lymphogranuloma venereum and nongonococcal urethritis, plague, cholera, brucellosis, tularemia, and others caused by susceptible organisms. MINOCIN Intravenous is used when oral therapy is not adequate or tolerated.

Extended-release oral minocycline tablets are indicated specifically for inflammatory lesions of moderate to severe acne vulgaris in patients 12 years and older — not for treating infections. AMZEEQ (topical foam) treats inflammatory lesions of moderate to severe acne vulgaris in patients 9 years and older. ZILXI (topical foam) and EMROSI (oral capsule) are indicated for inflammatory lesions of rosacea in adults. ARESTIN (oral powder placed by a dental professional) is used alongside scaling and root planing to reduce pocket depth in adult periodontitis.

See full Minocycline drug information
Keep checking

Other Drugs & Arrach

Browse every other medication we’ve checked against Arrach — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
334Moderate
0Minor
2,495No known interaction
334 Moderate 2,495 No interaction
Moderate

334 interactions

Showing 60 of 334 moderate interactions — see all 334 on the Arrach page.

No interaction 2,495 drugs checked — show the list

We also checked Arrach against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,495 medications checked with no known interaction — see the full Arrach list.

See the full Arrach interactions page
See every supplement checked against Minocycline, ranked by severity
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Arrach monograph › Uses, safety, and every drug interaction in one place Minocycline supplement interactions › Every supplement checked against Minocycline, ranked by severity Minocycline drug information › The full plain-English guide to this medication Supplement interaction checker › Check any supplement or product against your medications Browse medications A–Z › Every drug we've checked against herbs & supplements Ask a pharmacist › Free, personal answer from our licensed team
Pharmacist Counseling Corner

Taking Arrach and Minocycline Together: Common Questions

Can you take Arrach with Minocycline?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Arrach and Minocycline interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Minocycline and Arrach?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.