Drug & supplement interaction

Black Raspberry + Lisinopril

Lisinopril brand names: Zestril, Prinivil, Qbrelis.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Black Raspberry and Lisinopril in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Black Raspberry and Lisinopril

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Lisinopril and Black Raspberry in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Black Raspberry at all — not against Lisinopril, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Black Raspberry safety at a glance

Black Raspberry overall Generally safe Generally safe when eaten as a food; concentrated supplements are less well studied.
Pregnancy Likely Safe When used orally in amounts commonly found in foods. There is insufficient reliable information available about the safety of black raspberry in medicinal amoun... Read the full pregnancy detail
Breastfeeding Likely Safe When used orally in amounts commonly found in foods. There is insufficient reliable information available about the safety of black raspberry in medicinal amoun... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Lisinopril and Black Raspberry? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Lisinopril’s Own FDA Label Lists

This is not an interaction — none of it involves Black Raspberry. These are the most notable effects listed in the ADVERSE REACTIONS section of Lisinopril’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • A stroke or mini-stroke Worth acting on
  • Pain or burning when passing urine Worth acting on
  • Memory problems Worth acting on
  • Dehydration Worth acting on
  • High potassium Worth acting on
  • Low sodium Worth acting on
  • Unsteadiness Worth acting on
  • Low blood sugar Worth acting on
  • A slow heartbeat Worth acting on
  • A heart attack Worth acting on

Showing the 10 most notable of 79 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Lisinopril. Read the label on DailyMed › Where a percentage is shown, it is the share of 313,746 voluntary FDA FAERS reports for Lisinopril that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Black Raspberry’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Black Raspberry side to compare — that is a limit of the record, not a statement that Black Raspberry has no side effects.

Special populations

Black Raspberry in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Safe

When used orally in amounts commonly found in foods. There is insufficient reliable information available about the safety of black raspberry in medicinal amounts during pregnancy or breast-feeding; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Overlapping uses

What Lisinopril Is Prescribed For, and What Black Raspberry Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Lisinopril is a prescription medicine with approved uses on its FDA label. Black Raspberry is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Lisinopril is prescribed for: Lisinopril treats high blood pressure (hypertension) in adults and children 6 years and older, and can be used alone or alongside other blood pressure medicines. Lowering blood pressure reduces the risk of strokes and heart attacks. The tablet combination product containing lisinopril and hydrochlorothiazide is specifically indicated for high blood pressure. Lisinopril is also used as an add-on therapy to reduce signs and symptoms of systolic heart failure, and to reduce the risk of death in people who are hemodynamically stable (have reasonably stable circulation) within 24 hours of an acute heart attack (acute myocardial infarction).

Black Raspberry has been studied for:

  • Hypertension studied, not established Black Raspberry has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Black Raspberry for hypertension

    Preliminary clinical research shows that taking black raspberry extract 1500 mg or 2500 mg orally daily for 8 weeks reduces 24-hour systolic blood pressure by 1-7 mmHg and nighttime systolic blood pressure by 2-5 mmHg compared to baseline in patients with prehypertension. Compared to the placebo group, these changes were significant.

    1 source cited
    1. 96303. Jeong HS, Hong SJ, Cho JY, et al. Effects of Rubus occidentalis extract on blood pressure in patients with prehypertension: Randomized, double-blinded, placebo-controlled clinical trial. Nutrition. 2016;32(4):461-7. PubMed

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Lisinopril on your own; if you are taking Black Raspberry for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Black Raspberry or Lisinopril

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Black Raspberry or Lisinopril, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Lisinopril

This page covers Black Raspberry only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Lisinopril page lists 167 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Asarabacca (major) and Siberian Cocklebur (major).

By severity: 6 major · 137 moderate · 24 minor.

From our pharmacist’s overview on the Lisinopril page

“Lisinopril is an ACE inhibitor that lowers blood pressure and protects the heart and kidneys, so the 167 supplements and herbs on this page warrant genuine care. Six carry a major rating, and those deserve your attention first.”

Reviewed by 2 · Jul 18, 2026

Open the Lisinopril interaction page

One more smart check

Taking Black Raspberry as Part of a Dietary Supplement Product? Check It for Interactions

We hold 183 real supplement products containing Black Raspberry, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Black Raspberry. Even though Black Raspberry itself has no known interaction with Lisinopril, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Black Raspberry and Lisinopril Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Black Raspberry
Top half

#445 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Lisinopril
Top 1%

#25 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Black Raspberry reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Black Raspberry and Lisinopril records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Black Raspberry

What is Black Raspberry?

Black Raspberry
  • Antioxidant support
  • Heart health
  • Oral and gum health
  • Cancer prevention (under study)
  • Inflammation

Black raspberry is a nutrient-rich fruit packed with antioxidants like anthocyanins and ellagic acid, and as a food it is generally safe and healthy. Some early research explores it for cancer prevention, oral health, and heart health, but the evidence is preliminary and far from proven. Enjoy it as part of a balanced diet, and talk to your pharmacist or doctor before using concentrated supplements.

Rubus occidentalis · Rosaceae · Fruit (berries); sometimes leaves and seeds · Fresh or frozen berries, juice, powder, capsules, extracts, lozenges, gels

An interaction check asks whether these two react with each other — it does not ask whether Black Raspberry is a good idea for someone in your situation. Here is what our Black Raspberry record says about it on its own.

Black Raspberry: dosing

There is no official or standardized dose of black raspberry for any health condition. As a food, you can simply enjoy the fresh or frozen berries.For supplements, juices, and powders, the amount varies widely between products. The best approach is to follow the directions on the product label and not exceed the recommended amount.

From our Black Raspberry monograph — the full record covers uses, side effects and every documented interaction.

Read the full Black Raspberry monograph & all interactions
Medication

About Lisinopril

What Is Lisinopril Used For?

Brand names: Zestril, Prinivil, Qbrelis

Lisinopril treats high blood pressure (hypertension) in adults and children 6 years and older, and can be used alone or alongside other blood pressure medicines. Lowering blood pressure reduces the risk of strokes and heart attacks. The tablet combination product containing lisinopril and hydrochlorothiazide is specifically indicated for high blood pressure.

Lisinopril is also used as an add-on therapy to reduce signs and symptoms of systolic heart failure, and to reduce the risk of death in people who are hemodynamically stable (have reasonably stable circulation) within 24 hours of an acute heart attack (acute myocardial infarction).

Most-Reported Side Effects for Lisinopril

From FAERS, the FDA’s public side-effect reporting system (313,746 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fatigue 20,515 reports
Nausea 19,130 reports
Diarrhea 17,858 reports
Dyspnea 14,363 reports
Dizziness 13,969 reports
See full Lisinopril drug information
Keep checking

Other Drugs & Black Raspberry

Browse every other medication we’ve checked against Black Raspberry — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Black Raspberry against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Black Raspberry list.

See the full Black Raspberry interactions page
See every supplement checked against Lisinopril, ranked by severity
Evidence & sources

Black Raspberry References

The 4 references that drive our Black Raspberry monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. An JH, Kim DL, Lee TB, et al. Effect of Rubus Occidentalis Extract on Metabolic Parameters in Subjects with Prediabetes: A Proof-of-concept, Randomized, Double-blind, Placebo-controlled Clinical Trial. Phytother Res. 2016;30(10):1634-40.
  2. Jeong HS, Hong SJ, Cho JY, et al. Effects of Rubus occidentalis extract on blood pressure in patients with prehypertension: Randomized, double-blinded, placebo-controlled clinical trial. Nutrition. 2016;32(4):461-7. PubMed
  3. Mallery SR, Tong M, Shumway BS, et al. Topical application of a mucoadhesive freeze-dried black raspberry gel induces clinical and histologic regression and reduces loss of heterozygosity events in premalignant oral intraepithelial lesions: results from a
  4. Jeong HS, Kim S, Hong SJ, et al. Black Raspberry Extract Increased Circulating Endothelial Progenitor Cells and Improved Arterial Stiffness in Patients with Metabolic Syndrome: A Randomized Controlled Trial. J Med Food. 2016;19(4):346-52. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Black Raspberry and Lisinopril Together: Common Questions

Is it safe to take Black Raspberry with Lisinopril?
We do not list a known interaction between Black Raspberry and Lisinopril. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Black Raspberry and Lisinopril used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Black Raspberry in each. That is a conversation for your prescriber, especially if Lisinopril is being adjusted to a target.
Does Lisinopril interact with any supplements?
Yes. Lisinopril has documented interactions with 167 supplements in our database — Black Raspberry is not one of them. The Lisinopril interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Black Raspberry monograph Uses, safety profile, and every drug interaction in one place Lisinopril drug information The full plain-English guide to this medication Lisinopril supplement interactions Every supplement checked against Lisinopril, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 4 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Lisinopril and Black Raspberry?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.