Drug & supplement interaction

Coenzyme Q10 + Aluminum Acetate

Aluminum Acetate brand name: Burow's Solution.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Coenzyme Q10 and Aluminum Acetate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Coenzyme Q10 and Aluminum Acetate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Aluminum Acetate and Coenzyme Q10 in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Coenzyme Q10 safety at a glance

Coenzyme Q10 overall Generally safe CoQ10 is generally well tolerated by most adults when used as directed.
Pregnancy Use caution There is not enough reliable safety data, so it is best to avoid unless your doctor advises otherwise.
Breastfeeding Use caution Safety while breastfeeding has not been well studied, so use caution and check with your doctor.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Pharmacist analysis

Although CoQ10 is considered relatively safe for most individuals, it does have some reported interactions that are important to be aware of.

This includes:

  • Antihypertensives: Clinical research has shown that CoQ10 can significantly lower blood pressure but conflicting results have been reported.
  • Warfarin: Research is conflicting but concomitant use of CoQ10 and warfarin might reduce the anticoagulant effects of warfarin.
  • Alkylating Agents: Antioxidants such as CoQ10 might also protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy.

Outside of the interactions I've listed above, CoQ10 is generally considered safe to supplement with in most situations.

In fact, some individuals taking certain medications (e.g., 'Statins') may be recommended to take it.

If you have any questions about CoQ10 supplements, be sure to speak to your healthcare professional. We are always happy to answer questions on the matter as well!

Still wondering about combining Aluminum Acetate and Coenzyme Q10? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Aluminum Acetate

Interactions in our licensed database are recorded against drug classes, not just single drug names. Aluminum Acetate is filed under a single classification — topical drugs. Coenzyme Q10 has documented interactions with 3 drug classes — the most serious being alkylating agents (moderate), warfarin (coumadin) (moderate) and antihypertensive drugs (minor) — and none of Aluminum Acetate’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Coenzyme Q10 Does Interact With Other Medications

Coenzyme Q10 has 26 moderate, 172 minor known drug interactions in our database — Aluminum Acetate isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Coenzyme Q10

Covers the 2,830 medications we’ve checked against Coenzyme Q10. Pick one to open its full report.

What to actually watch for

What Coenzyme Q10 Itself Has Been Linked To

This is not an interaction — nothing below involves Aluminum Acetate. It is the side-effect record for Coenzyme Q10 on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Coenzyme Q10, this list is the first place to look. 5 entries are worth acting on rather than waiting out — marked below.

  • Bleeding in the gut / Bleeding or bruising Worth acting on Additional detail

    “Gastrointestinal side effects of coenzyme Q10 have included nausea, vomiting, epigastric discomfort, constipation, diarrhea, stomach upset, loss of appetite, heartburn, and flatulence, although this occurs in less than 1% of patients. In one clinical study, gastrointestinal bleeding in association with angiodysplasia has been reported to be possibly related to coenzyme Q10 treatment.”

    Coenzyme Q10 · Natural Medicines adverse-effect record, reported in constipation.

    6 sources cited
    1. 3365. Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
    2. 6409. Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
    3. 8907. Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
    4. 10152. Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
    5. 43982. Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
    6. 44172. Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
  • A heart attack Worth acting on Additional detail

    “Palpitations have been reported as being possibly associated with coenzyme Q10 treatment. Death due to myocardial infarction occurred in one Parkinson disease patient taking coenzyme Q10; causality is unclear.”

    Coenzyme Q10 · Natural Medicines adverse-effect record, reported in myocardial infarction (mi).

    2 sources cited
    1. 89421. Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.
    2. 15395. Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
  • Heart failure Worth acting on Additional detail

    “Two of 143 participants in a case series reported skin itching after starting treatment with oral coenzyme Q10. Allergic rash has also been reported.

    An itching exanthema was seen in two heart failure patients treated with intravenous coenzyme Q10.”

    Coenzyme Q10 · Natural Medicines adverse-effect record, reported in congestive heart failure (chf).

    4 sources cited
    1. 6047. Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
    2. 6409. Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
    3. 11872. Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
    4. 44284. Ishiyama, T., Morita, Y., Toyama, S., Yamagami, T., and Tsukamoto, N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn.Heart J 1976;17(1):32-42. PubMed
  • Low mood Worth acting on Additional detail

    “Headache and dizziness have been reported in human research. Insomnia has been reported as being possibly associated with coenzyme Q10 treatment. Cognitive decline, depression, and sudden falls were reported rarely in a clinical trial of patients with Huntington disease. Increased lethargy was reported for one patient treated with oral coenzyme Q10.”

    Coenzyme Q10 · Natural Medicines adverse-effect record, reported in cluster headache.

    6 sources cited
    1. 3365. Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
    2. 11872. Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
    3. 43982. Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
    4. 44330. Singh, R. B., Wander, G. S., Rastogi, A., Shukla, P. K., Mittal, A., Sharma, J. P., Mehrotra, S. K., Kapoor, R., and Chopra, R. K. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc. PubMed
    5. 109392. Hansen KS, Mogensen TH, Agergaard J, et al. High-dose coenzyme Q10 therapy versus placebo in patients with post COVID-19 condition: A randomized, phase 2, crossover trial. Lancet Reg Health Eur 2022. PubMed
    6. 89421. Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.

    “Worsening depression has been reported as being possibly associated with oral coenzyme Q10 treatment.”

    Coenzyme Q10 · Natural Medicines adverse-effect record, reported in depression.

    1 source cited
    1. 89421. Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.
  • A low platelet count / A higher chance of infection Worth acting on Additional detail

    “Thrombocytopenia was noted in one patient treated with oral coenzyme Q10; however, other factors (viral infection, other medications) may have been responsible for this adverse effect.”

    Coenzyme Q10 · Natural Medicines adverse-effect record, reported in thrombocytopenia.

    1 source cited
    1. 44296. Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A., Karpati, G., Andermann, F., and Arnold, D. L. Coenzyme Q10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease. Neurology 1993;43(5
  • Heartburn Additional detail

    “Orally, coenzyme Q10 is generally well tolerated. In clinical studies, no serious adverse effects have been reported.

    Most Common Adverse Effects:

    Orally: Gastrointestinal side effects such as appetite suppression, diarrhea, epigastric discomfort, heartburn, nausea, and vomiting. These generally occur in less than 1% of patients. Some of these adverse effects can be minimized if daily doses above 100 mg are divided.”

    Coenzyme Q10 · Natural Medicines adverse-effect record, reported in diarrhea.

  • Tremor or shakiness Additional detail

    Recorded for Coenzyme Q10 in the same Natural Medicines adverse-effect record shown under Low mood above.

  • Bloating or gas Additional detail

    Recorded for Coenzyme Q10 in the same Natural Medicines adverse-effect record shown under Bleeding in the gut / Bleeding or bruising above.

Showing the 10 most notable of 24 recorded effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

Everything above comes from the Natural Medicines adverse-effect record for Coenzyme Q10 — expand a row for the licensed statement it rests on. We haven’t matched Aluminum Acetate to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Aluminum Acetate.

Everything else you take

See Every Supplement That Interacts With Aluminum Acetate

This page covers Coenzyme Q10 only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Aluminum Acetate page lists 3 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Dimethylsulfoxide (dmso) (moderate), Turpentine Oil (moderate) and Alchemilla (minor).

By severity: 2 moderate · 1 minor.

From our pharmacist’s overview on the Aluminum Acetate page

“Aluminum acetate (Burow's Solution) is the soak or compress people reach for with weepy rashes, athlete's foot, or swimmer's ear, and its three supplement interactions on file all come down to what else touches that same patch of skin. None is rated major, and this is a list most people can handle with a little attention rather than al…”

Reviewed by 2 · Jul 18, 2026

Open the Aluminum Acetate interaction page

One more smart check

Taking Coenzyme Q10 as Part of a Dietary Supplement Product? Check It for Interactions

We hold 6,926 real supplement products containing Coenzyme Q10, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Coenzyme Q10. Even though Coenzyme Q10 itself has no known interaction with Aluminum Acetate, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Coenzyme Q10 and Aluminum Acetate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Coenzyme Q10
Top 5%

#36 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Aluminum Acetate
Steady interest

#2,156 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Coenzyme Q10 reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Coenzyme Q10 and Aluminum Acetate records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Coenzyme Q10

What is Coenzyme Q10?

  • Heart health
  • Statin-related muscle aches
  • Migraine prevention
  • Energy and fatigue
  • Aging and antioxidant support

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated and is most studied for heart conditions, statin-related muscle symptoms, and migraine prevention, though the strength of the evidence varies. Talk with your pharmacist or doctor before starting it, especially if you take heart or blood pressure medicines.

Not applicable (naturally made in the body; supplements are produced by fermentation or synthesis) · Capsules, softgels, tablets, chewables, liquid, topical creams

An interaction check asks whether these two react with each other — it does not ask whether Coenzyme Q10 is a good idea for someone in your situation. Here is what our Coenzyme Q10 record says about it on its own.

Coenzyme Q10: dosing

There is no single official or standardized dose of CoQ10, and the amount studied has varied widely depending on the condition. Products also differ in their form (ubiquinone versus ubiquinol) and how well they are absorbed.Because CoQ10 is fat-soluble, it is generally absorbed better when taken with a meal that contains some fat. They can help you choose a reasonable dose and a quality product.

From our Coenzyme Q10 monograph — the full record covers uses, side effects and every documented interaction.

Read the full Coenzyme Q10 monograph & all interactions
Medication

About Aluminum Acetate

What Is Aluminum Acetate Used For?

Brand name: Burow's Solution

Aluminum acetate is applied to the skin to temporarily ease the itch, irritation, and discomfort of a range of common skin conditions. Most products — including Tricalm Hydrogel, TriCalm, and Dermeleve cream — are used for poison ivy, poison oak, poison sumac, insect bites, athlete's foot, and rashes caused by soaps, detergents, cosmetics, or jewelry.

Dermeleve cream also lists minor burns among its uses. Dermeleve Anti Itch Scalp Serum is specifically formulated for scalp itch and rashes from soaps, detergents, or cosmetics applied to the scalp. The ZO Skin Health powder products target rashes from soaps, detergents, cosmetics, or jewelry.

Most-Reported Side Effects for Aluminum Acetate

From FAERS, the FDA’s public side-effect reporting system (40 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Headache 19 reports
Hypersensitivity 16 reports
Nausea 16 reports
Therapeutic product effect decreased 16 reports
Contraindicated product administered 6 reports
See full Aluminum Acetate drug information
Keep checking

Other Drugs & Coenzyme Q10

Browse every other medication we’ve checked against Coenzyme Q10 — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
26Moderate
172Minor
2,631No known interaction
Moderate

26 interactions

Minor

172 interactions

Showing 60 of 172 minor interactions — see all 172 on the Coenzyme Q10 page.

No interaction 2,631 drugs checked — show the list
Evidence & sources

Coenzyme Q10 References

The 40 references that drive our Coenzyme Q10 monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
  2. Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
  3. Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
  4. Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
  5. Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
  6. Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
  7. Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
  8. Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
  9. Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
  10. Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
  11. Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
  12. The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
  13. Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
  14. Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
  15. Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Coenzyme Q10 and Aluminum Acetate Together: Common Questions

Is it safe to take Coenzyme Q10 with Aluminum Acetate?
We do not list a known interaction between Coenzyme Q10 and Aluminum Acetate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Coenzyme Q10 and Aluminum Acetate combination checked?
Interactions in our licensed database are recorded against drug classes. Aluminum Acetate is filed under 1 classification, and Coenzyme Q10 has documented interactions with 3 drug classes — none of Aluminum Acetate's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Coenzyme Q10 interact with any other medications?
Yes. Coenzyme Q10 has 198 documented drug interactions in our database — Aluminum Acetate is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Aluminum Acetate interact with any supplements?
Yes. Aluminum Acetate has documented interactions with 3 supplements in our database — Coenzyme Q10 is not one of them. The Aluminum Acetate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Aluminum Acetate and Coenzyme Q10?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.