Drug & supplement interaction

Galphimia Glauca + Palifermin

Palifermin brand name: Kepivance.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Galphimia Glauca and Palifermin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Galphimia Glauca and Palifermin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Palifermin and Galphimia Glauca in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Galphimia Glauca safety at a glance

Galphimia Glauca overall Use caution Short-term studies suggest it is generally well tolerated, but long-term safety data are limited.
Pregnancy Avoid There is not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid There is not enough safety information, so it is best avoided while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Palifermin and Galphimia Glauca? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Palifermin

Interactions in our licensed database are recorded against drug classes, not just single drug names. Palifermin is filed under a single classification — oral drugs. Galphimia Glauca has documented interactions with 1 drug class — the most serious being cns depressants (moderate) — and none of Palifermin’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Galphimia Glauca Does Interact With Other Medications

Galphimia Glauca has 248 moderate known drug interactions in our database — Palifermin isn’t one of them. If you take anything else, check it against the full list below.

Moderate 248 No known interaction 2,582 (incl. Palifermin)
Taking anything else?

Check Another of Your Medications Against Galphimia Glauca

Covers the 2,830 medications we’ve checked against Galphimia Glauca. Pick one to open its full report.

What to actually watch for

What Galphimia Glauca Itself Has Been Linked To

This is not an interaction — nothing below involves Palifermin. It is the side-effect record for Galphimia Glauca on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Galphimia Glauca, this list is the first place to look.

  • Drowsiness / Headache Additional detail

    “Orally, Galphimia glauca extract 7-14 mg daily has been associated with sedation and headache. Rarely, restlessness, nervousness, weakness, and other side effects have been reported; but it is unclear if Galphimia glauca was the causal factor.”

    Galphimia Glauca · Natural Medicines adverse-effect record, reported in cluster headache.

    1 source cited
    1. 99507. Herrera-Arellano A, Jiménez-Ferrer JE, Zamilpa A, García-Alonso G, Herrera-Alvarez S, Tortoriello J. Therapeutic effectiveness of Galphimia glauca vs. lorazepam in generalized anxiety disorder. A controlled 15-week clinical trial. Planta Med. 2012;78(14): PubMed
  • Anxiety or restlessness Additional detail

    Recorded for Galphimia Glauca in the same Natural Medicines adverse-effect record shown under Drowsiness / Headache above.

  • Nausea Additional detail

    “Orally, Galphimia glauca extract 7-14 mg daily has been associated with nausea and epigastric burning.”

    Galphimia Glauca · Natural Medicines adverse-effect record, reported in myasthenia gravis.

    1 source cited
    1. 99507. Herrera-Arellano A, Jiménez-Ferrer JE, Zamilpa A, García-Alonso G, Herrera-Alvarez S, Tortoriello J. Therapeutic effectiveness of Galphimia glauca vs. lorazepam in generalized anxiety disorder. A controlled 15-week clinical trial. Planta Med. 2012;78(14): PubMed

Everything above comes from the Natural Medicines adverse-effect record for Galphimia Glauca — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Palifermin’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Palifermin column appears here.

Everything else you take

See Every Supplement That Interacts With Palifermin

This page covers Galphimia Glauca only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Palifermin page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Palifermin page

“Palifermin (Kepivance) is given by IV to prevent the severe mouth sores that intensive chemotherapy can cause, most often in patients heading into a stem cell transplant, and I read its interaction list with genuine caution because of how fragile those patients already are. All 17 supplements on file act on absorption through the gut,…”

Reviewed by 2 · Jul 18, 2026

Open the Palifermin interaction page

How much people look this up

Where Galphimia Glauca and Palifermin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Galphimia Glauca
Steady interest

#1,362 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Palifermin
Steady interest

#2,024 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Galphimia Glauca reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Galphimia Glauca and Palifermin records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Galphimia Glauca

What is Galphimia Glauca?

Galphimia Glauca
  • Anxiety and stress
  • Insomnia
  • Allergic rhinitis and hay fever
  • Respiratory complaints
  • Traditionally used as an anticonvulsant

Galphimia glauca is a shrub from Mexico and Central America that has been studied mainly for anxiety, with some small clinical trials suggesting possible benefit. Overall the evidence is still limited and its long-term safety is not well established, so talk with your pharmacist or doctor before using it.

Galphimia glauca · Malpighiaceae · Leaves and aerial parts · Capsules, standardized extracts, tinctures, homeopathic preparations, tea

An interaction check asks whether these two react with each other — it does not ask whether Galphimia Glauca is a good idea for someone in your situation. Here is what our Galphimia Glauca record says about it on its own.

Galphimia Glauca: dosing

There is no well-established standard dose of Galphimia glauca. Clinical studies have used standardized extracts, but products on the market vary widely in their strength and how they are made.Because of this, follow the directions on the product label and do not exceed the recommended amount.

From our Galphimia Glauca monograph — the full record covers uses, side effects and every documented interaction.

Read the full Galphimia Glauca monograph & all interactions
Medication

About Palifermin

What Is Palifermin Used For?

Brand name: Kepivance

Kepivance (palifermin) is used to decrease how often and how long severe oral mucositis — painful sores in the mouth and throat — occurs in patients with hematologic malignancies (blood cancers such as lymphoma, leukemia, or multiple myeloma) who are receiving high-dose, cell-damaging (myelotoxic) therapy before an autologous hematopoietic stem cell transplant (a transplant using the patient's own stem cells).

Kepivance is specifically indicated when the preparative chemotherapy or radiation regimen is expected to cause severe mucositis in most patients. It is not recommended for use with a high-dose melphalan conditioning regimen, and it was not found to be effective in the setting of allogeneic stem cell transplant (using a donor's cells). Its safety and effectiveness have not been established for patients with non-blood cancers (non-hematologic malignancies).

Most-Reported Side Effects for Palifermin

From FAERS, the FDA’s public side-effect reporting system (388 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Mucosal inflammation 56 reports
Febrile neutropenia 39 reports
Rash 39 reports
Stomatitis 34 reports
Erythema 28 reports
See full Palifermin drug information
Keep checking

Other Drugs & Galphimia Glauca

Browse every other medication we’ve checked against Galphimia Glauca — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
248Moderate
0Minor
2,581No known interaction
248 Moderate 2,581 No interaction
Moderate

248 interactions

Showing 60 of 248 moderate interactions — see all 248 on the Galphimia Glauca page.

No interaction 2,581 drugs checked — show the list

We also checked Galphimia Glauca against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,581 medications checked with no known interaction — see the full Galphimia Glauca list.

See the full Galphimia Glauca interactions page
See every supplement checked against Palifermin, ranked by severity
Evidence & sources

Galphimia Glauca References

The 2 references that drive our Galphimia Glauca monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Herrera-Arellano, A., Jimenez-Ferrer, E., Zamilpa, A., et al. Efficacy and tolerability of a standardized herbal product from Galphimia glauca on generalized anxiety disorder. A randomized, double-blind clinical trial controlled with lorazepam. Planta Med
  2. Herrera-Arellano A, Jiménez-Ferrer JE, Zamilpa A, García-Alonso G, Herrera-Alvarez S, Tortoriello J. Therapeutic effectiveness of Galphimia glauca vs. lorazepam in generalized anxiety disorder. A controlled 15-week clinical trial. Planta Med. 2012;78(14): PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Galphimia Glauca and Palifermin Together: Common Questions

Is it safe to take Galphimia Glauca with Palifermin?
We do not list a known interaction between Galphimia Glauca and Palifermin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Galphimia Glauca and Palifermin combination checked?
Interactions in our licensed database are recorded against drug classes. Palifermin is filed under 1 classification, and Galphimia Glauca has documented interactions with 1 drug class — none of Palifermin's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Galphimia Glauca interact with any other medications?
Yes. Galphimia Glauca has 248 documented drug interactions in our database — Palifermin is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Palifermin interact with any supplements?
Yes. Palifermin has documented interactions with 17 supplements in our database — Galphimia Glauca is not one of them. The Palifermin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Galphimia Glauca monograph Uses, safety profile, and every drug interaction in one place Palifermin drug information The full plain-English guide to this medication Palifermin supplement interactions Every supplement checked against Palifermin, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Palifermin and Galphimia Glauca?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.