Drug & supplement interaction

Java Tea + Nateglinide

Nateglinide brand name: Starlix.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Oct 4, 2026
The bottom line No known interaction

We found no known interaction between Java Tea and Nateglinide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Java Tea and Nateglinide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Nateglinide and Java Tea in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Java Tea safety at a glance

Java Tea overall Use caution Generally considered well tolerated short-term, but human safety data are limited.
Pregnancy Avoid Not enough safety data, so it is best avoided during pregnancy.
Breastfeeding Avoid Not enough safety data, so it is best avoided while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Nateglinide and Java Tea? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Nateglinide

Interactions in our licensed database are recorded against drug classes, not just single drug names. Nateglinide is filed under 3 classifications — antidiabetes drugs, cytochrome p450 2c9 (cyp2c9) substrates, oral drugs. Java Tea has documented interactions with 2 drug classes — the most serious being antihypertensive drugs (moderate) and lithium (moderate) — and none of Nateglinide’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Java Tea Does Interact With Other Medications

Java Tea has 173 moderate known drug interactions in our database — Nateglinide isn’t one of them. If you take anything else, check it against the full list below.

Moderate 173 No known interaction 2,657 (incl. Nateglinide)
Taking anything else?

Check Another of Your Medications Against Java Tea

Covers the 2,830 medications we’ve checked against Java Tea. Pick one to open its full report.

What to actually watch for

What Nateglinide’s Own FDA Label Lists

This is not an interaction — none of it involves Java Tea. These are the most notable effects listed in the ADVERSE REACTIONS section of Nateglinide’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 7 of them are worth acting on rather than waiting out — marked below.

  • Low blood sugar Worth acting on
  • Yellowing of the skin or eyes Worth acting on
  • High blood sugar Worth acting on
  • Hives Worth acting on
  • Liver problems Worth acting on
  • A higher chance of infection Worth acting on
  • An allergic reaction Worth acting on
  • Weight gain
  • Back pain
  • Cough

Showing the 10 most notable of 15 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Nateglinide. Read the label on DailyMed › Java Tea’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Java Tea side to compare — that is a limit of the record, not a statement that Java Tea has no side effects.

Overlapping uses

What Nateglinide Is Prescribed For, and What Java Tea Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Nateglinide is a prescription medicine with approved uses on its FDA label. Java Tea is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Nateglinide is prescribed for: Nateglinide is used along with diet and exercise to improve blood sugar (glycemic) control in adults with type 2 diabetes. The supplied tablet labels, including the plain, film-coated and coated tablets, all list this same use. It is not for people with type 1 diabetes or for treating diabetic ketoacidosis (a dangerous buildup of acids in the blood).

Java Tea has been studied for:

  • Diabetes studied, not established Java Tea has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Java Tea for diabetes

    Although there has been interest in using oral Java tea for diabetes, there is insufficient reliable information about the clinical effects of Java tea for this condition.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Nateglinide on your own; if you are taking Java Tea for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Nateglinide

This page covers Java Tea only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Nateglinide page lists 290 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Siberian Cocklebur (major), Acai (moderate), Adrafinil (moderate) and African Wild Potato (moderate).

By severity: 2 major · 241 moderate · 47 minor.

From our pharmacist’s overview on the Nateglinide page

“People who take nateglinide (Starlix) with meals for type 2 diabetes are often drawn to supplements marketed for blood sugar, and that overlap is why these 290 interactions warrant real caution. Some 239 of the ingredients affect blood sugar on their own, most pushing it lower, so stacking them on nateglinide raises the odds of hypogly…”

Reviewed by 2 · Jul 18, 2026

Open the Nateglinide interaction page

One more smart check

Taking Java Tea as Part of a Dietary Supplement Product? Check It for Interactions

We hold 64 real supplement products containing Java Tea, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Java Tea. Even though Java Tea itself has no known interaction with Nateglinide, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Java Tea and Nateglinide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Java Tea
Steady interest

#1,228 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Nateglinide
Steady interest

#2,178 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Java Tea reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Java Tea and Nateglinide records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Java Tea

What is Java Tea?

  • Urinary tract health
  • Mild fluid retention
  • Kidney and bladder support
  • Mild diuretic ('water pill') effect
  • Digestive complaints

Java Tea is a Southeast Asian herb traditionally used as a gentle diuretic and for urinary tract and kidney support. Some early lab, animal, and small human studies are encouraging, but high-quality evidence in people is limited, so it should not replace proven treatments. Talk to a pharmacist or doctor before using it, especially if you have kidney problems or take other medicines.

Orthosiphon stamineus · Lamiaceae · Leaves and stems (aerial parts) · Tea, dried herb, capsules, liquid extracts, tinctures

An interaction check asks whether these two react with each other — it does not ask whether Java Tea is a good idea for someone in your situation. Here is what our Java Tea record says about it on its own.

Java Tea: dosing

There is no well-established standardized dose for Java Tea. The right amount can vary depending on the form (tea, capsule, or extract) and the strength of the product.The safest approach is to follow the directions on the product label and not exceed the recommended amount. Because Java Tea has a diuretic effect, it is also wise to stay well hydrated.

From our Java Tea monograph — the full record covers uses, side effects and every documented interaction.

Read the full Java Tea monograph & all interactions
Medication

About Nateglinide

What Is Nateglinide Used For?

Brand name: Starlix

Nateglinide is used along with diet and exercise to improve blood sugar (glycemic) control in adults with type 2 diabetes. The supplied tablet labels, including the plain, film-coated and coated tablets, all list this same use.

It is not for people with type 1 diabetes or for treating diabetic ketoacidosis (a dangerous buildup of acids in the blood).

See full Nateglinide drug information
Keep checking

Other Drugs & Java Tea

Browse every other medication we’ve checked against Java Tea — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
173Moderate
0Minor
2,656No known interaction
173 Moderate 2,656 No interaction
Moderate

173 interactions

Showing 60 of 173 moderate interactions — see all 173 on the Java Tea page.

No interaction 2,656 drugs checked — show the list

We also checked Java Tea against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,656 medications checked with no known interaction — see the full Java Tea list.

See the full Java Tea interactions page
See every supplement checked against Nateglinide, ranked by severity
Evidence & sources

Java Tea References

The 1 references that drive our Java Tea monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Cicero AF, De Sando V, Izzo R, Vasta A, Trimarco A, Borghi C. Effect of a combined nutraceutical containing Orthosiphon stamineus effect on blood pressure and metabolic syndrome components in hypertensive dyslipidaemic patients: a randomized clinical tria

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Java Tea and Nateglinide Together: Common Questions

Is it safe to take Java Tea with Nateglinide?
We do not list a known interaction between Java Tea and Nateglinide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Java Tea and Nateglinide used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Java Tea in each. That is a conversation for your prescriber, especially if Nateglinide is being adjusted to a target.
How was the Java Tea and Nateglinide combination checked?
Interactions in our licensed database are recorded against drug classes. Nateglinide is filed under 3 classifications, and Java Tea has documented interactions with 2 drug classes — none of Nateglinide's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Java Tea interact with any other medications?
Yes. Java Tea has 173 documented drug interactions in our database — Nateglinide is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Nateglinide interact with any supplements?
Yes. Nateglinide has documented interactions with 290 supplements in our database — Java Tea is not one of them. The Nateglinide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Java Tea monograph Uses, safety profile, and every drug interaction in one place Nateglinide drug information The full plain-English guide to this medication Nateglinide supplement interactions Every supplement checked against Nateglinide, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Nateglinide and Java Tea?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.