Ketogenic Diet - Aspirin, Codeine Phosphate, Methocarbamol Interaction

Interaction Details

Aspirin, Codeine Phosphate, Methocarbamol is classified as belonging to the following category: Anticoagulant/Antiplatelet Drugs

Although there is some concern that the ketogenic diet might have additive effects when used with anticoagulant and antiplatelet drugs, most clinical research does not show this effect.
One small observational study found that the ketogenic diet was associated with prolonged bleeding times in 16 of 51 (31%) children with epilepsy who were also on chronic anticonvulsant therapy. However, a larger observational study of 162 children with epilepsy taking chronic anticonvulsants has found that following the ketogenic diet does not increase the risk of bleeding, even in the 25 children undergoing surgery. Research in adults also has not reported changes in bleeding time.

Interaction Rating

Likelihood of Occurrence

Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

References

• Melchior RW, Dreher M, Ramsey E, Savoca M, Rosenthal T. Cardiopulmonary bypass considerations for pediatric patients on the ketogenic diet. Perfusion. 2015;30(5):423-6.
• Dressler A, Chiara H, Benninger F, et al. Effects of the ketogenic diet on platelet counts and global coagulation tests in childhood epilepsy. Seizure. 2020;80:31-37.

Ketogenic Diet - More Interactions

Ketogenic Diet interacts with 256 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.