Medication interaction hub

What Supplements Interact with Aspirin, Codeine Phosphate, Methocarbamol?

Aspirin, Codeine Phosphate, Methocarbamol brand name: Robaxisal C. Every interaction below applies to the brands too.

328 Interactions 12 Major 282 Moderate 34 Minor
Curated & coded by · Clinical Pharmacist · Updated October 1, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Aspirin, Codeine Phosphate, Methocarbamol? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Aspirin, Codeine Phosphate, Methocarbamol against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Alcohol is the single riskiest thing to combine with Robaxisal C (aspirin, codeine phosphate, and methocarbamol). Beer and wine both carry major ratings backed by solid human evidence, because codeine and methocarbamol already slow breathing and reflexes, and alcohol deepens that sedation. The full picture here calls for real vigilance. Of the 328 ingredients on file, 12 are rated major, and they cluster around two dangers, heavier sedation from 78 sedating supplements such as kava, and extra bleeding from more than 200 ingredients that amplify aspirin's blood-thinning effect.

The 282 moderate and 34 minor entries mostly extend those same themes. About 60 ingredients, goldenseal among them, can slow the liver enzyme that processes codeine, raising its level, and several fibers and charcoals can blunt absorption of oral doses, so space those well apart from your medication. A small kidney-toxicity group rounds it out. Read the major entries first.

— , Clinical Pharmacist · July 18, 2026

Major 12 Moderate 282 Minor 34 No known interaction 1,124

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Aspirin, Codeine Phosphate, Methocarbamol: Top Interactions at a Glance

The Aspirin, Codeine Phosphate, Methocarbamol supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 328 interacting ingredients — plus 1,124 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Aspirin, Codeine Phosphate, Methocarbamol Combinations Today

The Aspirin, Codeine Phosphate, Methocarbamol + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Moderate Likelihood Probable Willow Bark + Aspirin, Codeine Phosphate, Methocarbamoli

Theoretically, willow bark might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.

Read the full interaction Moderate Likelihood Possible Resveratrol + Aspirin, Codeine Phosphate, Methocarbamoli

Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Read the full interaction Moderate Likelihood Possible Nutmeg + Aspirin, Codeine Phosphate, Methocarbamoli

Theoretically, nutmeg might increase the risk of additive sedation when taken with CNS depressants.

Read the full interaction Moderate Likelihood Possible Horny Goat Weed + Aspirin, Codeine Phosphate, Methocarbamoli

Theoretically, horny goat weed might increase the risk of bleeding.

Read the full interaction Moderate Likelihood Possible Garlic + Aspirin, Codeine Phosphate, Methocarbamoli

Garlic may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Read the full interaction Moderate Likelihood Possible Nattokinase + Aspirin, Codeine Phosphate, Methocarbamoli

Nattokinase might increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.

Read the full interaction
The complete list

Every Supplement Checked Against Aspirin, Codeine Phosphate, Methocarbamol

All 1,452 ingredients in our database, ranked by severity — 328 with a Aspirin, Codeine Phosphate, Methocarbamol interaction on file and 1,124 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Aspirin, Codeine Phosphate, Methocarbamol?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Willow Bark with Aspirin, Codeine Phosphate, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, willow bark might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.

Full Willow Bark + Aspirin, Codeine Phosphate, Methocarbamol answer

Can you take Resveratrol with Aspirin, Codeine Phosphate, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Resveratrol + Aspirin, Codeine Phosphate, Methocarbamol answer

Can you take Nutmeg with Aspirin, Codeine Phosphate, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, nutmeg might increase the risk of additive sedation when taken with CNS depressants.

Full Nutmeg + Aspirin, Codeine Phosphate, Methocarbamol answer

Can you take Horny Goat Weed with Aspirin, Codeine Phosphate, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, horny goat weed might increase the risk of bleeding.

Full Horny Goat Weed + Aspirin, Codeine Phosphate, Methocarbamol answer

Can you take Garlic with Aspirin, Codeine Phosphate, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Garlic may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Garlic + Aspirin, Codeine Phosphate, Methocarbamol answer

Can you take Purple Nut Sedge with Aspirin, Codeine Phosphate, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro, purple nut sedge inhibits platelet aggregation.

Full Purple Nut Sedge + Aspirin, Codeine Phosphate, Methocarbamol answer

Can you take Quercetin with Aspirin, Codeine Phosphate, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase the effects and adverse effects of OAT3 substrates.

Full Quercetin + Aspirin, Codeine Phosphate, Methocarbamol answer

Can you take Rauvolfia Vomitoria with Aspirin, Codeine Phosphate, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking Rauvolfia vomitoria might cause additive sedative effects.

Full Rauvolfia Vomitoria + Aspirin, Codeine Phosphate, Methocarbamol answer

Can you take Rauwolscine with Aspirin, Codeine Phosphate, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking rauwolscine with seizure threshold lowering drugs might increase the risk of adverse convulsant effects.

Full Rauwolscine + Aspirin, Codeine Phosphate, Methocarbamol answer

Can you take Red Raspberry with Aspirin, Codeine Phosphate, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking red raspberry leaf with anticoagulant/antiplatelet drugs might increase the risk of bleeding.

Full Red Raspberry + Aspirin, Codeine Phosphate, Methocarbamol answer

Can you take Reishi Mushroom with Aspirin, Codeine Phosphate, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, high doses of reishi mushroom might increase the risk of bleeding.

Full Reishi Mushroom + Aspirin, Codeine Phosphate, Methocarbamol answer

Can you take Rhubarb with Aspirin, Codeine Phosphate, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, long-term use of anthraquinones from rhubarb might increase the risk of nephrotoxicity when used with nephrotoxic drugs.

Full Rhubarb + Aspirin, Codeine Phosphate, Methocarbamol answer

Can you take Rooibos with Aspirin, Codeine Phosphate, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.

Full Rooibos + Aspirin, Codeine Phosphate, Methocarbamol answer

Can you take Rose Hip with Aspirin, Codeine Phosphate, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, rose hip might reduce the effectiveness of anticoagulant or antiplatelet drugs.

Full Rose Hip + Aspirin, Codeine Phosphate, Methocarbamol answer

Can you take Rosemary with Aspirin, Codeine Phosphate, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.

Full Rosemary + Aspirin, Codeine Phosphate, Methocarbamol answer

Can you take Safflower with Aspirin, Codeine Phosphate, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.

Full Safflower + Aspirin, Codeine Phosphate, Methocarbamol answer

Can you take Saffron with Aspirin, Codeine Phosphate, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.

Full Saffron + Aspirin, Codeine Phosphate, Methocarbamol answer

Can you take Sage with Aspirin, Codeine Phosphate, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking sage might increase the sedative and adverse effects of CNS depressants.

Full Sage + Aspirin, Codeine Phosphate, Methocarbamol answer

Can you take Sassafras with Aspirin, Codeine Phosphate, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of sassafras with drugs with sedative properties may cause additive sedative effects.

Full Sassafras + Aspirin, Codeine Phosphate, Methocarbamol answer

Can you take Saw Palmetto with Aspirin, Codeine Phosphate, Methocarbamol?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.

Full Saw Palmetto + Aspirin, Codeine Phosphate, Methocarbamol answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Aspirin, Codeine Phosphate, Methocarbamol is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Aspirin, Codeine Phosphate, Methocarbamol, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Aspirin, Codeine Phosphate, Methocarbamol sits in 13 interaction categories. Open any one to see what the group means:

Anticoagulant/Antiplatelet Drugs 202 ingredients

Blood-thinning medications. Supplements with their own effects on clotting or platelets can add up with these drugs and raise bleeding risk.

202 of the supplement ingredients on this page reach Aspirin, Codeine Phosphate, Methocarbamol through this category.

Cns Depressants 78 ingredients

Central-nervous-system depressants. Sedating supplements can intensify drowsiness and slowed reactions when combined.

78 of the supplement ingredients on this page reach Aspirin, Codeine Phosphate, Methocarbamol through this category.

Cytochrome P450 2D6 (Cyp2D6) Substrates 60 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

60 of the supplement ingredients on this page reach Aspirin, Codeine Phosphate, Methocarbamol through this category.

Aspirin 22 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

22 of the supplement ingredients on this page reach Aspirin, Codeine Phosphate, Methocarbamol through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Aspirin, Codeine Phosphate, Methocarbamol through this category.

Nephrotoxic Drugs 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Aspirin, Codeine Phosphate, Methocarbamol through this category.

Seizure Threshold Lowering Drugs 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Aspirin, Codeine Phosphate, Methocarbamol through this category.

Narcotic Drugs 5 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

5 of the supplement ingredients on this page reach Aspirin, Codeine Phosphate, Methocarbamol through this category.

Nonsteroidal Anti-Inflammatory Drugs (Nsaids) 5 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

5 of the supplement ingredients on this page reach Aspirin, Codeine Phosphate, Methocarbamol through this category.

Organic Anion Transporter 1 (Oat1) Substrates 4 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

4 of the supplement ingredients on this page reach Aspirin, Codeine Phosphate, Methocarbamol through this category.

Organic Anion Transporter 3 (Oat3) Substrates 4 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

4 of the supplement ingredients on this page reach Aspirin, Codeine Phosphate, Methocarbamol through this category.

Skeletal Muscle Relaxants 3 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

3 of the supplement ingredients on this page reach Aspirin, Codeine Phosphate, Methocarbamol through this category.

Codeine 1 ingredient

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

1 of the supplement ingredient on this page reaches Aspirin, Codeine Phosphate, Methocarbamol through this category.

Related: does Aspirin, Codeine Phosphate, Methocarbamol deplete any nutrients?

Aspirin, Codeine Phosphate, Methocarbamol has 4 reported nutrient associations in the research literature — see the Aspirin, Codeine Phosphate, Methocarbamol nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Aspirin, Codeine Phosphate, Methocarbamol

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Aspirin, Codeine Phosphate, Methocarbamol.

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Products that contain Aspirin, Codeine Phosphate, Methocarbamol-interacting ingredients

Real supplements from the NIH label database that contain the top interacting ingredients on this page — each one is worth a full label check before combining with Aspirin, Codeine Phosphate, Methocarbamol.

Zi Sheng Teapills by Plum Flower contains Siberian Cocklebur Cold Away by Health Concerns contains Siberian Cocklebur Sugar Coated Bi Yan Pian by Plum Flower contains Siberian Cocklebur Pe Min Kan Wan by Plum Flower contains Siberian Cocklebur
Pharmacist Counseling Corner

Aspirin, Codeine Phosphate, Methocarbamol & Supplements: Common Questions

What supplements interact with Aspirin, Codeine Phosphate, Methocarbamol?
Our database currently documents 328 ingredients with a known Aspirin, Codeine Phosphate, Methocarbamol interaction (12 major, 282 moderate, 34 minor). The practical move: scan the major group first, then look up the exact supplements you take rather than reading all 328. The highest-ranked right now: Beer, Siberian Cocklebur, Wine.
Which Aspirin, Codeine Phosphate, Methocarbamol supplement interactions are the most serious?
The 12 major-rated combinations — led by Beer, Siberian Cocklebur, Wine, 1,4-butanediol and Activated Charcoal — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Aspirin, Codeine Phosphate, Methocarbamol?
Plenty of supplements coexist fine with Aspirin, Codeine Phosphate, Methocarbamol; a shorter list does not. Rather than memorizing it, check the specific ingredients on your labels — the ranked list above covers every one we've checked, and multi-ingredient products can be checked label-by-label with our scanner. Try the label scanner or the interaction checker.
Do brands like Robaxisal C have the same supplement interactions as Aspirin, Codeine Phosphate, Methocarbamol?
Yes — Robaxisal C all contain Aspirin, Codeine Phosphate, Methocarbamol, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Aspirin, Codeine Phosphate, Methocarbamol deplete any vitamins or nutrients?
It might — Aspirin, Codeine Phosphate, Methocarbamol has 4 reported nutrient-depletion associations in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Aspirin, Codeine Phosphate, Methocarbamol nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Aspirin, Codeine Phosphate, Methocarbamol and my other medications?
This page covers Aspirin, Codeine Phosphate, Methocarbamol against supplements and herbal ingredients. Checking Aspirin, Codeine Phosphate, Methocarbamol against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of October 1, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.