Drug & supplement interaction

Korean Pine + Lacosamide

Lacosamide brand names: Vimpat, Motpoly XR.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Korean Pine and Lacosamide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Korean Pine and Lacosamide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Lacosamide and Korean Pine in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Korean Pine safety at a glance

Korean Pine overall Use caution The nuts and oil are generally safe as food, but concentrated supplements are less studied.
Pregnancy Use caution Pine nuts as food are fine, but concentrated extracts have not been well studied, so avoid these.
Breastfeeding Use caution Food amounts are likely fine, but safety of supplements is unknown, so use caution.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Lacosamide and Korean Pine? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Lacosamide

Interactions in our licensed database are recorded against drug classes, not just single drug names. Lacosamide is filed under 3 classifications — cytochrome p450 2c9 (cyp2c9) substrates, cytochrome p450 3a4 (cyp3a4) substrates, oral drugs. Korean Pine has documented interactions with 1 drug class — the most serious being antihypertensive drugs (moderate) — and none of Lacosamide’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Korean Pine Does Interact With Other Medications

Korean Pine has 172 moderate known drug interactions in our database — Lacosamide isn’t one of them. If you take anything else, check it against the full list below.

Moderate 172 No known interaction 2,658 (incl. Lacosamide)
Taking anything else?

Check Another of Your Medications Against Korean Pine

Covers the 2,830 medications we’ve checked against Korean Pine. Pick one to open its full report.

What to actually watch for

What Lacosamide’s Own FDA Label Lists

This is not an interaction — none of it involves Korean Pine. These are the most notable effects listed in the ADVERSE REACTIONS section of Lacosamide’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 5 of them are worth acting on rather than waiting out — marked below.

  • Seizures Worth acting on mentioned in 22.4% of FDA reports for Lacosamide
  • Unsteadiness Worth acting on
  • Fainting Worth acting on
  • A severe skin reaction Worth acting on
  • An allergic reaction Worth acting on
  • Blurred vision
  • Drowsiness mentioned in 4.0% of FDA reports for Lacosamide
  • Trouble sleeping
  • Dizziness mentioned in 4.5% of FDA reports for Lacosamide
  • Tiredness mentioned in 3.9% of FDA reports for Lacosamide

Showing the 10 most notable of 14 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Lacosamide. Read the label on DailyMed › Where a percentage is shown, it is the share of 36,995 voluntary FDA FAERS reports for Lacosamide that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Korean Pine’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Korean Pine side to compare — that is a limit of the record, not a statement that Korean Pine has no side effects.

Everything else you take

See Every Supplement That Interacts With Lacosamide

This page covers Korean Pine only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Lacosamide page lists 151 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 107 moderate · 41 minor.

From our pharmacist’s overview on the Lacosamide page

“If you take lacosamide (Vimpat, Motpoly XR) for seizures, start with the three major entries here: grapefruit, St. John's wort, and activated charcoal.”

Reviewed by 2 · Jul 18, 2026

Open the Lacosamide interaction page

One more smart check

Taking Korean Pine as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2 real supplement products containing Korean Pine, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Korean Pine. Even though Korean Pine itself has no known interaction with Lacosamide, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Korean Pine and Lacosamide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Korean Pine
Steady interest

#757 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Lacosamide
Steady interest

#2,180 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Korean Pine reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Korean Pine and Lacosamide records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Korean Pine

What is Korean Pine?

  • Appetite control and weight management
  • Heart and cholesterol health
  • General nutrition and energy
  • Skin and antioxidant support
  • Cough and respiratory comfort (traditional)

Korean Pine is best known as the source of edible pine nuts and pine nut oil, which are nutritious foods rich in healthy fats. While some early research looks at pine nut oil for appetite and cholesterol, strong human evidence for any specific health benefit is limited. Treat it mainly as a food, and check with your pharmacist or doctor before using concentrated extracts.

Pinus koraiensis · Pinaceae · Seeds (pine nuts), seed oil, nuts, bark, and needles · Pine nuts (food), pine nut oil (capsules or liquid), needle tea, extracts

An interaction check asks whether these two react with each other — it does not ask whether Korean Pine is a good idea for someone in your situation. Here is what our Korean Pine record says about it on its own.

Korean Pine: dosing

There is no established standard medicinal dose for Korean Pine or pine nut oil. As a food, pine nuts are simply eaten in normal amounts as part of meals.For pine nut oil capsules or extracts, follow the directions on the product label, since strength varies between products.

From our Korean Pine monograph — the full record covers uses, side effects and every documented interaction.

Read the full Korean Pine monograph & all interactions
Medication

About Lacosamide

What Is Lacosamide Used For?

Brand names: Vimpat, Motpoly XR

Lacosamide is used to treat partial-onset seizures (seizures that start in one part of the brain) in adults and children. The age at which it is approved depends on the specific product: Vimpat tablets, oral solution, and injection are approved for partial-onset seizures in patients as young as 1 month old; most other formulations are approved from age 4 and up; and Motpoly XR is approved for patients weighing at least 50 kg.

Lacosamide is also used as adjunctive (add-on) therapy for primary generalized tonic-clonic seizures (grand mal seizures involving the whole brain) in adults and children 4 years of age and older, including Motpoly XR for patients weighing at least 50 kg.

Most-Reported Side Effects for Lacosamide

From FAERS, the FDA’s public side-effect reporting system (36,995 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Seizure 6,858 reports
Dizziness 1,669 reports
Somnolence 1,497 reports
Fatigue 1,446 reports
Epilepsy 1,418 reports
See full Lacosamide drug information
Keep checking

Other Drugs & Korean Pine

Browse every other medication we’ve checked against Korean Pine — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
172Moderate
0Minor
2,657No known interaction
172 Moderate 2,657 No interaction
Moderate

172 interactions

Showing 60 of 172 moderate interactions — see all 172 on the Korean Pine page.

No interaction 2,657 drugs checked — show the list

We also checked Korean Pine against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,657 medications checked with no known interaction — see the full Korean Pine list.

See the full Korean Pine interactions page
See every supplement checked against Lacosamide, ranked by severity
Evidence & sources

Korean Pine References

The 2 references that drive our Korean Pine monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Sugano M, Ikeda I, Wakamatsu K, Oka T. Influence of Korean pine (Pinus koraiensis)-seed oil containing cis-5,cis-9,cis-12-octadecatrienoic acid on polyunsaturated fatty acid metabolism, eicosanoid production and blood pressure of rats. Br J Nutr 1994;72(5
  2. Lee H, Kim H, Choue R, Lim H. Evaluation of the Effects of Pinus koraiensis Needle Extracts on Serum Lipid and Oxidative Stress in Adults with Borderline Dyslipidemia: A Randomized, Double-Blind, and Placebo-Controlled Clinical Trial. Evid Based Complemen

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Korean Pine and Lacosamide Together: Common Questions

Is it safe to take Korean Pine with Lacosamide?
We do not list a known interaction between Korean Pine and Lacosamide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Korean Pine and Lacosamide combination checked?
Interactions in our licensed database are recorded against drug classes. Lacosamide is filed under 3 classifications, and Korean Pine has documented interactions with 1 drug class — none of Lacosamide's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Korean Pine interact with any other medications?
Yes. Korean Pine has 172 documented drug interactions in our database — Lacosamide is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Lacosamide interact with any supplements?
Yes. Lacosamide has documented interactions with 151 supplements in our database — Korean Pine is not one of them. The Lacosamide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Korean Pine monograph Uses, safety profile, and every drug interaction in one place Lacosamide drug information The full plain-English guide to this medication Lacosamide supplement interactions Every supplement checked against Lacosamide, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Lacosamide and Korean Pine?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.