Drug & supplement interaction

Lactiplantibacillus Pentosus + Lomitapide

Lomitapide brand name: Juxtapid.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Lactiplantibacillus Pentosus and Lomitapide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Lactiplantibacillus Pentosus and Lomitapide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Lomitapide and Lactiplantibacillus Pentosus in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Lactiplantibacillus Pentosus safety at a glance

Lactiplantibacillu... overall Use caution Generally well tolerated in healthy people, but evidence is limited and some groups should be cautious.
Pregnancy Use caution Not enough safety data in pregnancy, so check with your doctor before using.
Breastfeeding Use caution Not enough safety data while breastfeeding, so check with your doctor before using.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Lomitapide and Lactiplantibacillus Pentosus? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Lomitapide

Interactions in our licensed database are recorded against drug classes, not just single drug names. Lomitapide is filed under 3 classifications — hepatotoxic drugs, cytochrome p450 3a4 (cyp3a4) substrates, oral drugs. Lactiplantibacillus Pentosus has documented interactions with 1 drug class — the most serious being antibiotic drugs (moderate) — and none of Lomitapide’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Lactiplantibacillus Pentosus Does Interact With Other Medications

Lactiplantibacillus Pentosus has 182 moderate known drug interactions in our database — Lomitapide isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Lactiplantibacillus Pentosus

Covers the 2,830 medications we’ve checked against Lactiplantibacillus Pentosus. Pick one to open its full report.

What to actually watch for

What Lactiplantibacillus Pentosus Itself Has Been Linked To

This is not an interaction — nothing below involves Lomitapide. It is the side-effect record for Lactiplantibacillus Pentosus on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Lactiplantibacillus Pentosus, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • A higher chance of infection Worth acting on Additional detail

    “Since Lactiplantibacillus pentosus preparations contain live and active microorganisms, there is some concern that they might cause pathogenic infection in some patients. Some lactobacilli species have been isolated in cases of bacteremia, sepsis, splenic abscess, endocarditis, necrotizing fasciitis, pancreatic necrosis, and meningoencephalitis.”

    Lactiplantibacillus Pentosus · Natural Medicines adverse-effect record, reported in sepsis.

    1 source cited
    1. 107543. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Lactiplantibacillus Pentosus — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Lomitapide’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Lomitapide column appears here.

Everything else you take

See Every Supplement That Interacts With Lomitapide

This page covers Lactiplantibacillus Pentosus only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Lomitapide page lists 168 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Grapefruit (major), Siberian Cocklebur (major) and St. John's Wort (major).

By severity: 6 major · 124 moderate · 38 minor.

From our pharmacist’s overview on the Lomitapide page

“If you take lomitapide (Juxtapid) for homozygous familial hypercholesterolemia, treat this page with real care. Lomitapide is cleared by one liver enzyme, CYP3A4, and 121 of the 168 supplements here can push its blood level up or down through that pathway; grapefruit and St.”

Reviewed by 2 · Jul 18, 2026

Open the Lomitapide interaction page

How much people look this up

Where Lactiplantibacillus Pentosus and Lomitapide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Lactiplantibacillus Pentosus
Steady interest

#1,220 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Lomitapide
Steady interest

#1,807 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Lactiplantibacillus Pentosus reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Lactiplantibacillus Pentosus and Lomitapide records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Lactiplantibacillus Pentosus

What is Lactiplantibacillus Pentosus?

  • Digestive and gut health
  • Immune support
  • Maintaining a healthy gut microbiome
  • Fermentation of foods (such as olives and vegetables)

Lactiplantibacillus pentosus is a 'friendly' probiotic bacterium found in many fermented foods and used in some supplements for gut and immune health. Research is still early, so it is not proven to treat any specific condition. It is generally considered safe for healthy adults, but people with weakened immune systems or serious illness should talk to a doctor first.

Lactiplantibacillus pentosus · Lactobacillaceae · Whole live bacterial cells (probiotic strain) · Capsules, powders, fermented foods, and some functional drinks

An interaction check asks whether these two react with each other — it does not ask whether Lactiplantibacillus Pentosus is a good idea for someone in your situation. Here is what our Lactiplantibacillus Pentosus record says about it on its own.

Lactiplantibacillus Pentosus: dosing

There is no established standard dose for Lactiplantibacillus pentosus. Probiotic products are usually measured in colony-forming units (CFU), and the amount can vary widely between products.The best approach is to follow the directions on the product label.

From our Lactiplantibacillus Pentosus monograph — the full record covers uses, side effects and every documented interaction.

Read the full Lactiplantibacillus Pentosus monograph & all interactions
Medication

About Lomitapide

What Is Lomitapide Used For?

Brand name: Juxtapid

Juxtapid (lomitapide) is used alongside a low-fat diet and other cholesterol-lowering treatments — including LDL apheresis (a procedure that filters LDL from the blood) where available — to lower LDL cholesterol, total cholesterol, apolipoprotein B, and non-HDL cholesterol in patients with homozygous familial hypercholesterolemia (HoFH). HoFH is a rare, inherited condition that causes extremely high LDL cholesterol levels from birth.

Juxtapid is approved for use in adults and in children aged 2 years and older with HoFH. It has not been proven safe or effective for other types of high cholesterol, including the more common heterozygous familial hypercholesterolemia (HeFH). Its effect on heart attacks, strokes, or other cardiovascular events has not been established.

See full Lomitapide drug information
Keep checking

Other Drugs & Lactiplantibacillus Pentosus

Browse every other medication we’ve checked against Lactiplantibacillus Pentosus — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
182Moderate
0Minor
2,647No known interaction
Moderate

182 interactions

Showing 60 of 182 moderate interactions — see all 182 on the Lactiplantibacillus Pentosus page.

No interaction 2,647 drugs checked — show the list
Evidence & sources

Lactiplantibacillus Pentosus References

The 2 references that drive our Lactiplantibacillus Pentosus monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Lactiplantibacillus Pentosus and Lomitapide Together: Common Questions

Is it safe to take Lactiplantibacillus Pentosus with Lomitapide?
We do not list a known interaction between Lactiplantibacillus Pentosus and Lomitapide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Lactiplantibacillus Pentosus and Lomitapide combination checked?
Interactions in our licensed database are recorded against drug classes. Lomitapide is filed under 3 classifications, and Lactiplantibacillus Pentosus has documented interactions with 1 drug class — none of Lomitapide's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Lactiplantibacillus Pentosus interact with any other medications?
Yes. Lactiplantibacillus Pentosus has 182 documented drug interactions in our database — Lomitapide is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Lomitapide interact with any supplements?
Yes. Lomitapide has documented interactions with 168 supplements in our database — Lactiplantibacillus Pentosus is not one of them. The Lomitapide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Lomitapide and Lactiplantibacillus Pentosus?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.