Drug & supplement interaction

Pangamic Acid + Ciclesonide

Ciclesonide brand names: Omnaris, Alvesco, Zetonna.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Oct 4, 2026
The bottom line No known interaction

We found no known interaction between Pangamic Acid and Ciclesonide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

Know someone taking this? Share
Facebook Post Reddit Email
On this page
Interaction report

Pangamic Acid and Ciclesonide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Ciclesonide and Pangamic Acid in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Pangamic Acid at all — not against Ciclesonide, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Pangamic Acid safety at a glance

Pangamic Acid overall Avoid It has no proven benefit, no standard composition, and some forms have raised safety concerns.
Pregnancy Possibly Unsafe When used orally; avoid using because it is difficult to know what constituents are present. Dichloroacetate, present in some formulations, is mutagenic accordi... Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally; avoid using because it is difficult to know what constituents are present. Dichloroacetate, present in some formulations, is mutagenic accordi... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Ciclesonide and Pangamic Acid? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Ciclesonide’s Own FDA Label Lists

This is not an interaction — none of it involves Pangamic Acid. These are the most notable effects listed in the ADVERSE REACTIONS section of Ciclesonide’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 7 of them are worth acting on rather than waiting out — marked below.

  • Wheezing Worth acting on mentioned in 70.7% of FDA reports for Ciclesonide
  • Bone thinning Worth acting on
  • Chest pain Worth acting on
  • A severe allergic reaction Worth acting on
  • Hives Worth acting on
  • A higher chance of infection Worth acting on
  • An allergic reaction Worth acting on
  • Cough mentioned in 19.0% of FDA reports for Ciclesonide
  • Pain in an arm or leg
  • A stuffy or runny nose

Showing the 10 most notable of 18 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Ciclesonide. Read the label on DailyMed › Where a percentage is shown, it is the share of 13,541 voluntary FDA FAERS reports for Ciclesonide that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Pangamic Acid’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Pangamic Acid side to compare — that is a limit of the record, not a statement that Pangamic Acid has no side effects.

Special populations

Pangamic Acid in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally; avoid using because it is difficult to know what constituents are present. Dichloroacetate, present in some formulations, is mutagenic according to the Ames test.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Overlapping uses

What Ciclesonide Is Prescribed For, and What Pangamic Acid Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Ciclesonide is a prescription medicine with approved uses on its FDA label. Pangamic Acid is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Ciclesonide is prescribed for: Alvesco (ciclesonide oral inhalation) is used for maintenance treatment of asthma. It is a preventive medicine for adults and teens 12 years of age and older. It is not a rescue inhaler. It does not relieve sudden breathing trouble (acute bronchospasm) and is not indicated for children under 12.

Pangamic Acid has been studied for:

  • Asthma studied, not established Pangamic Acid has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Pangamic Acid for asthma

    Although there has been interest in using oral pangamic acid for asthma, there is insufficient reliable information about the clinical effects of pangamic acid for this purpose.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Ciclesonide on your own; if you are taking Pangamic Acid for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Ciclesonide

This page covers Pangamic Acid only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Ciclesonide page lists 166 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate), Active Hexose Correlated Compound (ahcc) (moderate) and Adrafinil (moderate).

By severity: 2 major · 134 moderate · 30 minor.

From our pharmacist’s overview on the Ciclesonide page

“Ciclesonide (Alvesco, Omnaris, Zetonna) is a corticosteroid for asthma and nasal allergies, and even though it is inhaled rather than swallowed, its supplement list warrants genuine care. The body clears it through the CYP3A4 enzyme, and 121 of the 166 ingredients on file nudge that pathway one way or the other.”

Reviewed by 2 · Jul 18, 2026

Open the Ciclesonide interaction page

One more smart check

Taking Pangamic Acid as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1 real supplement products containing Pangamic Acid, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Pangamic Acid. Even though Pangamic Acid itself has no known interaction with Ciclesonide, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Pangamic Acid and Ciclesonide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Pangamic Acid
Steady interest

#1,034 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Ciclesonide
Top 25%

#501 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Pangamic Acid reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Pangamic Acid and Ciclesonide records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Pangamic Acid

What is Pangamic Acid?

  • Claimed athletic performance and endurance
  • General fatigue and energy
  • Heart and circulation support
  • Detoxification claims
  • Antioxidant claims

Pangamic acid, often marketed as 'vitamin B15,' is not a true vitamin and has no established health benefit. Its chemical makeup has never been consistent across products, some versions have raised safety concerns, and it is not approved as a supplement in the United States. We do not recommend using it.

Not a plant part; a synthetic or apricot-kernel-derived chemical compound · Tablets, capsules (often labeled 'B15' or 'vitamin B15')

An interaction check asks whether these two react with each other — it does not ask whether Pangamic Acid is a good idea for someone in your situation. Here is what our Pangamic Acid record says about it on its own.

Pangamic Acid: dosing

There is no established or recommended dose for pangamic acid, and no health authority endorses its use. In most cases, the best advice is to choose a different, well-studied option instead.

From our Pangamic Acid monograph — the full record covers uses, side effects and every documented interaction.

Read the full Pangamic Acid monograph & all interactions
Medication

About Ciclesonide Oral Inhalation

What Is Ciclesonide Oral Inhalation Used For?

Brand names: Omnaris, Alvesco, Zetonna

Alvesco (ciclesonide oral inhalation) is used for maintenance treatment of asthma. It is a preventive medicine for adults and teens 12 years of age and older.

It is not a rescue inhaler. It does not relieve sudden breathing trouble (acute bronchospasm) and is not indicated for children under 12.

Most-Reported Side Effects for Ciclesonide

From FAERS, the FDA’s public side-effect reporting system (13,541 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Asthma 5,858 reports
Dyspnea 4,621 reports
Wheezing 3,710 reports
Therapeutic product effect incomplete 2,598 reports
Cough 2,578 reports
See full Ciclesonide Oral Inhalation drug information Ciclesonide NDC codes and packages
Keep checking

Other Drugs & Pangamic Acid

Browse every other medication we’ve checked against Pangamic Acid — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Pangamic Acid against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Pangamic Acid list.

See the full Pangamic Acid interactions page
See every supplement checked against Ciclesonide, ranked by severity
Evidence & sources

Pangamic Acid References

The 1 references that drive our Pangamic Acid monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Pangamic Acid and Ciclesonide Together: Common Questions

Is it safe to take Pangamic Acid with Ciclesonide?
We do not list a known interaction between Pangamic Acid and Ciclesonide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Pangamic Acid and Ciclesonide used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Pangamic Acid in each. That is a conversation for your prescriber, especially if Ciclesonide is being adjusted to a target.
Does Ciclesonide interact with any supplements?
Yes. Ciclesonide has documented interactions with 166 supplements in our database — Pangamic Acid is not one of them. The Ciclesonide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Pangamic Acid monograph Uses, safety profile, and every drug interaction in one place Ciclesonide Oral Inhalation drug information The full plain-English guide to this medication Ciclesonide supplement interactions Every supplement checked against Ciclesonide, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Ciclesonide and Pangamic Acid?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.