Drug & supplement interaction

Picrorhiza + Reslizumab

Reslizumab brand name: Cinqair.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Picrorhiza and Reslizumab in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Picrorhiza and Reslizumab

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Reslizumab and Picrorhiza in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Picrorhiza safety at a glance

Picrorhiza overall Use caution Generally used in traditional medicine, but human safety data are limited, so use with care.
Pregnancy Avoid Not enough safety information; avoid use during pregnancy.
Breastfeeding Avoid Not enough safety information; avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Reslizumab and Picrorhiza? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
Keep it in perspective

Picrorhiza Does Interact With Other Medications

Picrorhiza has 207 moderate known drug interactions in our database — Reslizumab isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Picrorhiza

Covers the 2,830 medications we’ve checked against Picrorhiza. Pick one to open its full report.

What to actually watch for

What Picrorhiza Itself Has Been Linked To

This is not an interaction — nothing below involves Reslizumab. It is the side-effect record for Picrorhiza on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Picrorhiza, this list is the first place to look.

  • Reduced appetite / Diarrhea / Vomiting Additional detail

    “Orally, picrorhiza may cause vomiting, rash, anorexia, diarrhea, itching, and giddiness.”

    Picrorhiza · Natural Medicines adverse-effect record, reported in anorexia.

    1 source cited
    1. 11858. Doshi VB, Shetye VM, Mahashur AA, Kamat SR. Picrorrhiza kurroa in bronchial asthma. J Postgrad Med 1983;29:89-95.

    “Orally, picrorhiza may cause vomiting, anorexia, and diarrhea.”

    Picrorhiza · Natural Medicines adverse-effect record, reported in anorexia.

    1 source cited
    1. 11858. Doshi VB, Shetye VM, Mahashur AA, Kamat SR. Picrorrhiza kurroa in bronchial asthma. J Postgrad Med 1983;29:89-95.
  • Itching / A skin rash Additional detail

    “Orally, picrorhiza may cause rash and itching.”

    Picrorhiza · Natural Medicines adverse-effect record, reported in pruritus.

    1 source cited
    1. 11858. Doshi VB, Shetye VM, Mahashur AA, Kamat SR. Picrorrhiza kurroa in bronchial asthma. J Postgrad Med 1983;29:89-95.

Everything above comes from the Natural Medicines adverse-effect record for Picrorhiza — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Reslizumab’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Reslizumab column appears here.

Overlapping uses

What Reslizumab Is Prescribed For, and What Picrorhiza Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Reslizumab is a prescription medicine with approved uses on its FDA label. Picrorhiza is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Reslizumab is prescribed for: Cinqair (reslizumab) injection is indicated for adults 18 years and older with severe asthma that is driven by high eosinophil levels (a type of white blood cell involved in allergic inflammation). It is used as an add-on treatment, meaning it works alongside other asthma medicines the patient is already taking. Cinqair is not meant to treat sudden asthma attacks or to relieve symptoms in the moment. It is also not approved for other conditions caused by high eosinophil levels, and it is not approved for anyone under 18.

Picrorhiza has been studied for:

  • Asthma studied, not established Picrorhiza has been studied for this. Natural Medicines rates the evidence: Possibly Ineffective Read what the research shows

    Picrorhiza for asthma

    Taking picrorhiza orally for up to 12 weeks does not seem to help asthma symptoms or improve measurements of lung function.

    1 source cited
    1. 11858. Doshi VB, Shetye VM, Mahashur AA, Kamat SR. Picrorrhiza kurroa in bronchial asthma. J Postgrad Med 1983;29:89-95.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Reslizumab on your own; if you are taking Picrorhiza for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

One more smart check

Taking Picrorhiza as Part of a Dietary Supplement Product? Check It for Interactions

We hold 177 real supplement products containing Picrorhiza, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Picrorhiza. Even though Picrorhiza itself has no known interaction with Reslizumab, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Picrorhiza and Reslizumab Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Picrorhiza
Top 25%

#300 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Reslizumab
Top 25%

#567 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Picrorhiza reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Picrorhiza and Reslizumab records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Picrorhiza

What is Picrorhiza?

  • Liver support
  • Digestive complaints
  • Asthma and breathing problems
  • Skin conditions
  • Fever
  • Immune support

Picrorhiza (Picrorhiza kurroa) is a bitter Himalayan herb used in Ayurvedic medicine, mainly for liver and digestive complaints. Early lab and small human studies suggest possible liver-protective and anti-inflammatory effects, but high-quality evidence is limited. Talk with your pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Picrorhiza kurroa · Plantaginaceae · Roots and rhizomes · Capsules, tablets, powder (churna), liquid extracts, and traditional herbal formulas

An interaction check asks whether these two react with each other — it does not ask whether Picrorhiza is a good idea for someone in your situation. Here is what our Picrorhiza record says about it on its own.

Picrorhiza: dosing

There is no well-established standard dose of Picrorhiza. The amount used can vary widely depending on the form (powder, capsule, or extract) and how concentrated the product is.The safest approach is to follow the dosing directions on the product label and not to exceed them.

From our Picrorhiza monograph — the full record covers uses, side effects and every documented interaction.

Read the full Picrorhiza monograph & all interactions
Medication

About Reslizumab Injection

What Is Reslizumab Injection Used For?

Brand name: Cinqair

Cinqair (reslizumab) injection is indicated for adults 18 years and older with severe asthma that is driven by high eosinophil levels (a type of white blood cell involved in allergic inflammation). It is used as an add-on treatment, meaning it works alongside other asthma medicines the patient is already taking.

Cinqair is not meant to treat sudden asthma attacks or to relieve symptoms in the moment. It is also not approved for other conditions caused by high eosinophil levels, and it is not approved for anyone under 18.

See full Reslizumab Injection drug information
Keep checking

Other Drugs & Picrorhiza

Browse every other medication we’ve checked against Picrorhiza — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
207Moderate
0Minor
2,622No known interaction
Moderate

207 interactions

Showing 60 of 207 moderate interactions — see all 207 on the Picrorhiza page.

No interaction 2,622 drugs checked — show the list
Evidence & sources

Picrorhiza References

The 7 references that drive our Picrorhiza monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Sharma ML, Rao CS, Duda PL. Immunostimulatory activity of Picrorhiza kurroa leaf extract. J Ethnopharmacol 1994;41:185-92. PubMed
  2. Bedi KL, Zutshi U, Chopra CL, Amla V. Picrorhiza kurroa, an ayurvedic herb, may potentiate photochemotherapy in vitiligo. J Ethnopharmacol 1989;27:347-52. PubMed
  3. Vaidya AB, Antarkar DS, Doshi JC, et al. Picrorhiza kurroa (Kutaki) Royle ex Benth as a hepatoprotective agent--experimental & clinical studies. J Postgrad Med 1996;42:105-8.
  4. Baruah CC, Gupta PP, Nath A, et al. Anti-allergic and anti-anaphylactic activity of picroliv--a standardised iridoid glycoside fraction of Picrorhiza kurroa. Pharmacol Res 1998;38:487-92.
  5. Doshi VB, Shetye VM, Mahashur AA, Kamat SR. Picrorrhiza kurroa in bronchial asthma. J Postgrad Med 1983;29:89-95.
  6. Joy, K. L. and Kuttan, R. Anti-diabetic activity of Picrorrhiza kurroa extract. J Ethnopharmacol 11-1-1999;67(2):143-148. PubMed
  7. Brockwell C, Ampikaipakan S, Sexton DW, Price D, Freeman D, Thomas M, Ali M, Wilson AM. Adjunctive treatment with oral AKL1, a botanical nutraceutical, in chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis 2014;9:715-21. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Picrorhiza and Reslizumab Together: Common Questions

Is it safe to take Picrorhiza with Reslizumab?
We do not list a known interaction between Picrorhiza and Reslizumab. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Picrorhiza and Reslizumab used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Picrorhiza in each. That is a conversation for your prescriber, especially if Reslizumab is being adjusted to a target.
Does Picrorhiza interact with any other medications?
Yes. Picrorhiza has 207 documented drug interactions in our database — Reslizumab is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Reslizumab and Picrorhiza?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.