Drug & supplement interaction

Shilajit + Secnidazole

Secnidazole brand name: Solosec.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Shilajit and Secnidazole in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Shilajit and Secnidazole

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Secnidazole and Shilajit in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Shilajit safety at a glance

Shilajit overall Use caution Unpurified products may contain heavy metals or other contaminants, so only use purified, tested brands.
Pregnancy Avoid Not enough safety data and contamination risk, so it is best avoided during pregnancy.
Breastfeeding Avoid Safety is unknown while breastfeeding, so avoid it.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Secnidazole and Shilajit? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Secnidazole

Interactions in our licensed database are recorded against drug classes, not just single drug names. Secnidazole is filed under 3 classifications — including antibiotic drugs, oral drugs. Shilajit has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of Secnidazole’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Shilajit Does Interact With Other Medications

Shilajit has 86 moderate known drug interactions in our database — Secnidazole isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Shilajit

Covers the 2,830 medications we’ve checked against Shilajit. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Shilajit and Secnidazole May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Headache reported in 7.1% of FDA reports for Secnidazole Additional detail

    Shilajit

    “Orally, headache is reported rarely following shilajit intake in clinical research.”

    Shilajit · Natural Medicines adverse-effect record, reported in cluster headache.

    1 source cited
    1. 112616. Sadeghi SMH, Hosseini Khameneh SM, Khodadoost M, et al. Efficacy of momiai in tibia fracture repair: A randomized double-blinded placebo-controlled clinical trial. J Altern Complement Med 2020;26(6):521-528.

    Secnidazole

    Listed in the ADVERSE REACTIONS section of the FDA label for Secnidazole, and in voluntary FDA adverse-event reports. Read the label on DailyMed ›

Reported for Shilajit but not commonly for Secnidazole: raised blood pressure, low potassium, a severe allergic reaction and swelling.

Effects for Secnidazole come from the ADVERSE REACTIONS section of its FDA label; effects for Shilajit come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 280 voluntary FDA FAERS reports for Secnidazole that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

From our Q&A

Questions About Shilajit or Secnidazole

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Shilajit or Secnidazole, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Secnidazole

This page covers Shilajit only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Secnidazole page lists 46 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Bacillus Coagulans (moderate), Bacillus Subtilis (moderate), Beer (moderate) and Bifidobacterium Animalis Subsp. Lactis (moderate).

By severity: 1 major · 35 moderate · 10 minor.

From our pharmacist’s overview on the Secnidazole page

“Secnidazole (Solosec) usually comes as a single-dose packet for bacterial vaginosis, and that single dose raises the stakes for the one major interaction on this list: activated charcoal, which can soak up the drug in the gut and cut how much your body actually absorbs. Blunt that one dose and the infection may simply not clear, so tre…”

Reviewed by 2 · Jul 18, 2026

Open the Secnidazole interaction page

One more smart check

Taking Shilajit as Part of a Dietary Supplement Product? Check It for Interactions

We hold 525 real supplement products containing Shilajit, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Shilajit. Even though Shilajit itself has no known interaction with Secnidazole, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Shilajit and Secnidazole Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Shilajit
Top 25%

#303 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Secnidazole
Steady interest

#1,846 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Shilajit reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Shilajit and Secnidazole records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Shilajit

What is Shilajit?

  • Fatigue and low energy
  • Male fertility and testosterone support
  • General vitality and aging
  • Athletic performance
  • Cognitive support

Shilajit is a sticky, tar-like substance found in rocks of mountain ranges like the Himalayas, used in traditional Ayurvedic medicine for energy and vitality. Human evidence is limited and mostly small or early-stage, so its real benefits are uncertain. Quality and purity vary widely, and contamination with heavy metals is a real concern, so choose tested products and talk to your pharmacist before use.

Mineral exudate (resin) from rock layers · Resin, capsules, powder, tablets

An interaction check asks whether these two react with each other — it does not ask whether Shilajit is a good idea for someone in your situation. Here is what our Shilajit record says about it on its own.

Shilajit: dosing

There is no well-established standard dose for shilajit, and products vary a lot in strength and form. Choose products that have been independently tested for heavy metals and contaminants.

From our Shilajit monograph — the full record covers uses, side effects and every documented interaction.

Read the full Shilajit monograph & all interactions
Medication

About Secnidazole

What Is Secnidazole Used For?

Brand name: Solosec

Solosec (secnidazole) oral powder is used to treat two distinct infections. The first is bacterial vaginosis — an imbalance of bacteria in the vagina — in female patients aged 12 and older. The second is trichomoniasis, a sexually transmitted infection caused by the parasite Trichomonas vaginalis, in patients aged 12 and older.

Because trichomoniasis spreads between partners, sexual partners of infected patients should be treated at the same time to prevent reinfection. Solosec should only be used for infections that are proven or strongly suspected to be caused by susceptible bacteria or the relevant organism — using antibiotics unnecessarily can lead to drug resistance.

See full Secnidazole drug information
Keep checking

Other Drugs & Shilajit

Browse every other medication we’ve checked against Shilajit — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
86Moderate
0Minor
2,743No known interaction
Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Shilajit page.

No interaction 2,743 drugs checked — show the list
Evidence & sources

Shilajit References

The 8 references that drive our Shilajit monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Sadeghi SMH, Hosseini Khameneh SM, Khodadoost M, et al. Efficacy of momiai in tibia fracture repair: A randomized double-blinded placebo-controlled clinical trial. J Altern Complement Med 2020;26(6):521-528.
  2. Losa F, Deidda M, Firinu D, Martino MLD, Barca MP, Giacco SD. Exercise-induced anaphylaxis with an Ayurvedic drug as cofactor: A case report. World J Clin Cases 2019;7(5):623-627. PubMed
  3. Biswas TK, Pandit S, Mondal S, et al. Clinical evaluation of spermatogenic activity of processed Shilajit in oligospermia. Andrologia 2010;42(1):48-56. PubMed
  4. Stavropoulos K, Sotiriadis A, Patoulias D, et al. Pseudohyperaldosteronism due to mumijo consumption during pregnancy: a licorice-like syndrome. Gynecol Endocrinol 2018;34(12):1019-1021. PubMed
  5. Ghezelbash B, Shahrokhi N, Khaksari M, Ghaderi-Pakdel F, Asadikaram G. Hepatoprotective effects of shilajit on high fat-diet induced non-alcoholic fatty liver disease (NAFLD) in rats. Horm Mol Biol Clin Investig 2020;41(1):/j/hmbci. PubMed
  6. Ghezelbash B, Shahrokhi N, Khaksari M, Asadikaram G, Shahrokhi M, Shirazpour S. Protective roles of shilajit in modulating resistin, adiponectin, and cytokines in rats with non-alcoholic fatty liver disease. Chin J Integr Med 2022;28(6):531-537. PubMed
  7. Jafari M, Forootanfar H, Ameri A, et al. Antioxidant, cytotoxic and hyperalgesia-suppressing activity of a native Shilajit obtained from Bahr Aseman mountains. Pak J Pharm Sci 2019;32(5):2167-2173. DOI
  8. Trivedi NA, Mazumdar B, Bhatt JD, Hemavathi KG. Effect of shilajit on blood glucose and lipid profile in alloxan-induced diabetic rats. Ind. J. Pharmacol. 2004; 36(6):373-376.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Shilajit and Secnidazole Together: Common Questions

Is it safe to take Shilajit with Secnidazole?
We do not list a known interaction between Shilajit and Secnidazole. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Shilajit and Secnidazole have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Shilajit and Secnidazole combination checked?
Interactions in our licensed database are recorded against drug classes. Secnidazole is filed under 3 classifications, and Shilajit has documented interactions with 1 drug class — none of Secnidazole's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Shilajit interact with any other medications?
Yes. Shilajit has 86 documented drug interactions in our database — Secnidazole is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Secnidazole interact with any supplements?
Yes. Secnidazole has documented interactions with 46 supplements in our database — Shilajit is not one of them. The Secnidazole interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Secnidazole and Shilajit?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.