Medication interaction hub

What Supplements Interact with LetibotulinumtoxinA-wlbg?

LetibotulinumtoxinA-wlbg brand name: Letybo. Every interaction below applies to the brands too.

33 Interactions 3 Major 28 Moderate 2 Minor
Curated & coded by · Clinical Pharmacist · Updated September 19, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with LetibotulinumtoxinA-wlbg? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check LetibotulinumtoxinA-wlbg against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Letybo (letibotulinumtoxinA-wlbg) relaxes targeted muscles by blocking nerve signals, and a number of supplements push on that same system, so I would treat this list with real care rather than a quick skim. Three of the 33 ingredients carry a major rating (henbane, scopolia, and procaine), and those belong at the top of your reading. The dominant theme, covering 30 of the entries, is anticholinergic activity: herbs containing atropine-like compounds that can stack dry mouth, blurred vision, and confusion on top of the drug's own effects, or in some cases blunt them.

A smaller cluster works more directly on the muscles. Lithium and magnesium supplements may prolong neuromuscular blockade, meaning the muscle-weakening effect could run longer or stronger than intended. Because Letybo is usually a cosmetic injection for frown lines, it is easy to forget it counts as a real medication. Beyond the three majors, 28 entries rate moderate and only 2 minor, so tell your injector everything botanical you take before the appointment.

— , Clinical Pharmacist · July 18, 2026

Major 3 Moderate 28 Minor 2 No known interaction 1,419

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Top Ingredient Interactions

LetibotulinumtoxinA-wlbg: Top Interactions at a Glance

The most significant LetibotulinumtoxinA-wlbg supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 33 interacting ingredients — plus 1,419 more checked with no known interaction. See the complete ranked list.

Start here

The Major Interactions to Know About

The most clinically significant LetibotulinumtoxinA-wlbg + supplement combinations in our database, best-documented first. Open any card for the full report.

Major Likelihood Probable Henbane + LetibotulinumtoxinA-wlbgi

Concomitant use of henbane can have additive anticholinergic effects and adverse effects with amantadine, antihistamines, atropine, belladonna alkaloids, hyoscy...

Read the full interaction Major Likelihood Probable Procaine + LetibotulinumtoxinA-wlbgi

Intravenous use of procaine hydrochloride is contraindicated.

Read the full interaction Major Likelihood Probable Scopolia + LetibotulinumtoxinA-wlbgi

The alkaloid constituents of scopolia, including hyoscyamine, scopolamine, and atropine, could potentiate the effects and adverse effects of anticholinergic dru...

Read the full interaction
The complete list

Every Supplement Checked Against LetibotulinumtoxinA-wlbg

All 1,452 ingredients in our database, ranked by severity — 33 with a LetibotulinumtoxinA-wlbg interaction on file and 1,419 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With LetibotulinumtoxinA-wlbg?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Lithium with LetibotulinumtoxinA-wlbg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking lithium supplements with skeletal muscle relaxants might prolong neuromuscular blockade.

Full Lithium + LetibotulinumtoxinA-wlbg answer

Can you take Magnesium with LetibotulinumtoxinA-wlbg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect...

Full Magnesium + LetibotulinumtoxinA-wlbg answer

Can you take Angel's Trumpet with LetibotulinumtoxinA-wlbg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Concomitant use may increase anticholinergic effects and adverse effects.

Full Angel's Trumpet + LetibotulinumtoxinA-wlbg answer

Can you take Bacopa with LetibotulinumtoxinA-wlbg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use might decrease the effectiveness of both agents.

Full Bacopa + LetibotulinumtoxinA-wlbg answer

Can you take Boxwood with LetibotulinumtoxinA-wlbg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Evidence from in vitro research suggests that boxwood extract can inhibit acetylcholinesterase activity.

Full Boxwood + LetibotulinumtoxinA-wlbg answer

Can you take Calamus with LetibotulinumtoxinA-wlbg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use of anticholinergic drugs and calamus might decrease the effectiveness of the anticholinergic drug.

Full Calamus + LetibotulinumtoxinA-wlbg answer

Can you take Clubmoss with LetibotulinumtoxinA-wlbg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Evidence from in vitro research suggests that clubmoss extract can inhibit acetylcholinesterase activity.

Full Clubmoss + LetibotulinumtoxinA-wlbg answer

Can you take Corkwood Tree with LetibotulinumtoxinA-wlbg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, corkwood tree might increase the risk of adverse anticholinergic effects when taken with anticholinergic drugs.

Full Corkwood Tree + LetibotulinumtoxinA-wlbg answer

Can you take European Barberry with LetibotulinumtoxinA-wlbg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking European barberry with anticholinergic drugs might cause additive effects.

Full European Barberry + LetibotulinumtoxinA-wlbg answer

Can you take European Mandrake with LetibotulinumtoxinA-wlbg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Concurrent use may cause additive anticholinergic effects and adverse effects.

Full European Mandrake + LetibotulinumtoxinA-wlbg answer

Can you take Huperzine A with LetibotulinumtoxinA-wlbg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, huperzine A might decrease the effects of anticholinergic drugs.

Full Huperzine A + LetibotulinumtoxinA-wlbg answer

Can you take Iboga with LetibotulinumtoxinA-wlbg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, iboga might decrease the effectiveness of anticholinergic drugs.

Full Iboga + LetibotulinumtoxinA-wlbg answer

Can you take Jimson Weed with LetibotulinumtoxinA-wlbg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, jimson weed may increase anticholinergic effects and adverse effects.

Full Jimson Weed + LetibotulinumtoxinA-wlbg answer

Can you take Marjoram with LetibotulinumtoxinA-wlbg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro research suggests that marjoram extract can inhibit acetylcholinesterase activity.

Full Marjoram + LetibotulinumtoxinA-wlbg answer

Can you take Methylene Blue with LetibotulinumtoxinA-wlbg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Concomitant use may increase anticholinergic effects and adverse effects.

Full Methylene Blue + LetibotulinumtoxinA-wlbg answer

Can you take Nutmeg with LetibotulinumtoxinA-wlbg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of nutmeg and anticholinergic drugs might decrease the effectiveness of either agent.

Full Nutmeg + LetibotulinumtoxinA-wlbg answer

Can you take Phosphatidylserine with LetibotulinumtoxinA-wlbg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.

Full Phosphatidylserine + LetibotulinumtoxinA-wlbg answer

Can you take Poria Mushroom with LetibotulinumtoxinA-wlbg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.

Full Poria Mushroom + LetibotulinumtoxinA-wlbg answer

Can you take Purple Nut Sedge with LetibotulinumtoxinA-wlbg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro, purple nut sedge dose-dependently inhibits acetylcholinesterase (AChE).

Full Purple Nut Sedge + LetibotulinumtoxinA-wlbg answer

Can you take Sage with LetibotulinumtoxinA-wlbg?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, sage might decrease the clinical effects of anticholinergic drugs.

Full Sage + LetibotulinumtoxinA-wlbg answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) LetibotulinumtoxinA-wlbg is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by LetibotulinumtoxinA-wlbg, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

LetibotulinumtoxinA-wlbg sits in 2 interaction categories. Open any one to see what the group means:

Anticholinergic Drugs 30 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

30 of the supplement ingredients on this page reach LetibotulinumtoxinA-wlbg through this category.

Skeletal Muscle Relaxants 3 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

3 of the supplement ingredients on this page reach LetibotulinumtoxinA-wlbg through this category.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against LetibotulinumtoxinA-wlbg

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against LetibotulinumtoxinA-wlbg.

Search a supplement product

Type a product name, brand, or UPC — smart search across our full catalog.

Grounded search over our product catalog — every verdict comes from our interaction database, never AI guesswork. How we use AI

Or scan the bottle

Photograph any Supplement Facts panel — we read the ingredients and check each one against your medications. Free, in seconds.

Open the label scanner

Prefer typing? The interaction checker looks up products by name too.

Pharmacist Counseling Corner

LetibotulinumtoxinA-wlbg & Supplements: Common Questions

What supplements interact with LetibotulinumtoxinA-wlbg?
Our database currently documents 33 ingredients with a known LetibotulinumtoxinA-wlbg interaction (3 major, 28 moderate, 2 minor). The practical move: scan the major group first, then look up the exact supplements you take rather than reading all 33. The highest-ranked right now: Henbane, Procaine, Scopolia.
Which LetibotulinumtoxinA-wlbg supplement interactions are the most serious?
Focus on the major group: Henbane, Procaine and Scopolia. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on LetibotulinumtoxinA-wlbg?
Plenty of supplements coexist fine with LetibotulinumtoxinA-wlbg; a shorter list does not. Rather than memorizing it, check the specific ingredients on your labels — the ranked list above covers every one we've checked, and multi-ingredient products can be checked label-by-label with our scanner. Try the label scanner or the interaction checker.
Do brands like Letybo have the same supplement interactions as LetibotulinumtoxinA-wlbg?
Yes — Letybo all contain LetibotulinumtoxinA-wlbg, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about LetibotulinumtoxinA-wlbg and my other medications?
This page covers LetibotulinumtoxinA-wlbg against supplements and herbal ingredients. Checking LetibotulinumtoxinA-wlbg against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

More Free Pharmacist Tools

Supplement interaction checker Check any supplement or product against your medications Supplement label scanner Photograph a Supplement Facts panel; we check every ingredient Browse medications A–Z Every drug we’ve checked against herbs & supplements Ingredient directory Every vitamin, herb & mineral we track, with interaction data Product directory Look up any bottle by name, brand, or barcode Ask a pharmacist Free, personal answer from our licensed team
Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 19, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.