Medication interaction hub

What Supplements Interact with Liraglutide Recombinant?

Liraglutide Recombinant brand name: Saxenda. Every interaction below applies to the brands too.

239 Interactions 1 Major 208 Moderate 30 Minor
Curated & coded by · Clinical Pharmacist · Updated October 5, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Liraglutide Recombinant? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Liraglutide Recombinant against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

If you take liraglutide (Saxenda), handle this page with real care, because all 239 ingredients on it act on the same thing the drug does, your blood sugar. The one major entry, Siberian cocklebur, has caused severe hypoglycemia, dangerously low blood sugar, in people and should never be combined with a glucose-lowering medicine. Most of the others, bitter melon for example, can drag your sugar lower than Saxenda alone would, while a smaller group, niacin included, pushes it up and blunts the drug's effect.

The rest are less alarming, 208 moderate and 30 minor, most resting on small studies rather than proven harm, but direction matters. Shakiness, sweating, or sudden hunger after starting a supplement points to low sugar; unexplained higher readings point the other way. Check your glucose more often for the first couple of weeks after adding anything from this list, and skip the cocklebur entirely.

— , Clinical Pharmacist · July 18, 2026

Major 1 Moderate 208 Minor 30 No known interaction 1,213

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Top Ingredient Interactions

Liraglutide Recombinant: Top Interactions at a Glance

The most significant Liraglutide Recombinant supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 239 interacting ingredients — plus 1,213 more checked with no known interaction. See the complete ranked list.

Start here

The Major Interactions to Know About

The most clinically significant Liraglutide Recombinant + supplement combinations in our database, best-documented first. Open any card for the full report.

Major Likelihood Likely Siberian Cocklebur + Liraglutide Recombinanti

Siberian cocklebur seedlings and seeds have caused severe hypoglycemia in humans.

Read the full interaction
The complete list

Every Supplement Checked Against Liraglutide Recombinant

All 1,452 ingredients in our database, ranked by severity — 239 with a Liraglutide Recombinant interaction on file and 1,213 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Liraglutide Recombinant?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Ashwagandha with Liraglutide Recombinant?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking ashwagandha with antidiabetes drugs might increase the risk of hypoglycemia.

Full Ashwagandha + Liraglutide Recombinant answer

Can you take Apple Cider Vinegar with Liraglutide Recombinant?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, taking apple cider vinegar with antidiabetes drugs might increase the risk of hypoglycemia.

Full Apple Cider Vinegar + Liraglutide Recombinant answer

Can you take Oregano with Liraglutide Recombinant?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.

Full Oregano + Liraglutide Recombinant answer

Can you take Glucosamine with Liraglutide Recombinant?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Despite initial concerns, it is unlikely that glucosamine will interfere with the effects of antidiabetes drugs.

Full Glucosamine + Liraglutide Recombinant answer

Can you take Green Coffee with Liraglutide Recombinant?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, taking green coffee and antidiabetes drugs might interfere with blood glucose control.

Full Green Coffee + Liraglutide Recombinant answer

Can you take Green Tea with Liraglutide Recombinant?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, taking green tea with antidiabetes drugs might interfere with blood glucose control.

Full Green Tea + Liraglutide Recombinant answer

Can you take Guarana with Liraglutide Recombinant?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, taking guarana with antidiabetes drugs might interfere with blood glucose control.

Full Guarana + Liraglutide Recombinant answer

Can you take Ilex Guayusa with Liraglutide Recombinant?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, taking Ilex guayusa with antidiabetes drugs might increase the risk of hypoglycemia.

Full Ilex Guayusa + Liraglutide Recombinant answer

Can you take Inulin with Liraglutide Recombinant?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.

Full Inulin + Liraglutide Recombinant answer

Can you take Kudzu with Liraglutide Recombinant?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, taking kudzu with antidiabetes drugs might increase the risk of hypoglycemia.

Full Kudzu + Liraglutide Recombinant answer

Can you take Mommy's Bliss Gripe Water with Liraglutide Recombinant?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Mommy's Bliss Gripe Water contains ginger.

Full Mommy's Bliss Gripe Water + Liraglutide Recombinant answer

Can you take Oolong Tea with Liraglutide Recombinant?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, taking oolong tea with antidiabetes drugs might interfere with blood glucose control.

Full Oolong Tea + Liraglutide Recombinant answer

Can you take Pu-erh Tea with Liraglutide Recombinant?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, taking pu-erh tea with antidiabetes drugs might interfere with blood glucose control.

Full Pu-erh Tea + Liraglutide Recombinant answer

Can you take Yerba Mate with Liraglutide Recombinant?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, taking yerba mate with antidiabetes drugs might interfere with blood glucose control.

Full Yerba Mate + Liraglutide Recombinant answer

Can you take Siberian Cocklebur with Liraglutide Recombinant?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Siberian cocklebur seedlings and seeds have caused severe hypoglycemia in humans.

Full Siberian Cocklebur + Liraglutide Recombinant answer

Can you take American Ginseng with Liraglutide Recombinant?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.

Full American Ginseng + Liraglutide Recombinant answer

Can you take Astragalus with Liraglutide Recombinant?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.

Full Astragalus + Liraglutide Recombinant answer

Can you take Banaba with Liraglutide Recombinant?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of banaba and hypoglycemic drugs might have additive effects.

Full Banaba + Liraglutide Recombinant answer

Can you take Beer with Liraglutide Recombinant?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Concomitant use may interfere with blood glucose control.

Full Beer + Liraglutide Recombinant answer

Can you take Bitter Melon with Liraglutide Recombinant?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Taking bitter melon with antidiabetes drugs might increase the risk of hypoglycemia.

Full Bitter Melon + Liraglutide Recombinant answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Liraglutide Recombinant is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Liraglutide Recombinant, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Liraglutide Recombinant sits in 1 interaction category. Open any one to see what the group means:

Antidiabetes Drugs 239 ingredients

Blood-sugar-lowering medications. Supplements that also lower glucose can push blood sugar too low when combined.

239 of the supplement ingredients on this page reach Liraglutide Recombinant through this category.

About Liraglutide Recombinant

Liraglutide injection is a once-daily GLP-1 receptor agonist; in the Saxenda product it is used with diet and exercise for chronic weight management in adults and in children 12 and older with obesity.

Generic name: Liraglutide Recombinant  ·  Brand name: Saxenda.

See the full Liraglutide Injection drug information

Related: does Liraglutide Recombinant deplete any nutrients?

Liraglutide Recombinant has 1 reported nutrient association in the research literature — see the Liraglutide Recombinant nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Liraglutide Recombinant

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Liraglutide Recombinant.

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Pharmacist Counseling Corner

Liraglutide Recombinant & Supplements: Common Questions

What supplements interact with Liraglutide Recombinant?
In our interaction database, 239 supplement and herbal ingredients have an interaction with Liraglutide Recombinant on file — 1 rated major, 208 moderate, and 30 minor. That number sounds scarier than it is: severity matters far more than the count, which is why the list on this page is ranked instead of alphabetical. Start at the top. The highest-ranked right now: Siberian Cocklebur, American Ginseng, Astragalus.
Which Liraglutide Recombinant supplement interactions are the most serious?
Focus on the major group: Siberian Cocklebur. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Liraglutide Recombinant?
That depends entirely on which supplement. The honest answer for Liraglutide Recombinant is in the ranked list above — and if what you take is a combination product with a dozen ingredients, don't check them one by one: photograph the label with our scanner and we'll check the whole thing at once. Try the label scanner or the interaction checker.
Do brands like Saxenda have the same supplement interactions as Liraglutide Recombinant?
Yes — Saxenda all contain Liraglutide Recombinant, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Liraglutide Recombinant deplete any vitamins or nutrients?
It might — Liraglutide Recombinant has 1 reported nutrient-depletion association in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Liraglutide Recombinant nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Liraglutide Recombinant and my other medications?
This page covers Liraglutide Recombinant against supplements and herbal ingredients. Checking Liraglutide Recombinant against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Liraglutide Injection drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of October 5, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.