Hawthorn + Liraglutide Recombinant
Liraglutide Recombinant brand name: Saxenda.
We found no known interaction between Hawthorn and Liraglutide Recombinant in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.
Hawthorn and Liraglutide Recombinant
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Liraglutide Recombinant and Hawthorn in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Hawthorn safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Liraglutide Recombinant
Interactions in our licensed database are recorded against drug classes, not just single drug names. Liraglutide Recombinant is filed under a single classification — antidiabetes drugs. Hawthorn has documented interactions with 6 drug classes — the most serious being nitrates (major), phosphodiesterase-5 inhibitors (major) and anticoagulant/antiplatelet drugs (moderate) — and none of Liraglutide Recombinant’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Hawthorn Does Interact With Other Medications
Hawthorn has 14 major, 177 moderate known drug interactions in our database — Liraglutide Recombinant isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Hawthorn
We haven’t checked that one against Hawthorn yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Hawthorn. Pick one to open its full report.
What Liraglutide Recombinant Is Prescribed For, and What Hawthorn Has Been Studied For
These two come up together because they touch the same health topic — not because they do the same job. Liraglutide Recombinant is a prescription medicine with approved uses on its FDA label. Hawthorn is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.
Liraglutide Recombinant is prescribed for: Saxenda is used alongside a reduced-calorie diet and increased physical activity for chronic weight management. It is approved for adults with a BMI of 30 or higher, or a BMI of 27 or higher if they also have at least one weight-related condition such as high blood pressure, type 2 diabetes, or dyslipidemia (abnormal cholesterol or fat levels). It is also approved for adolescents aged 12 and older who weigh more than 60 kg and meet certain BMI thresholds for obesity. Saxenda should not be used together with other liraglutide-containing products or any other GLP-1 receptor agonist.
Read the rest of what Liraglutide Recombinant is prescribed for
Its safety and effectiveness in combination with other prescription or over-the-counter weight-loss products have not been established.
Hawthorn has been studied for:
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Obesity studied, not established Hawthorn has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows
Hawthorn for obesity
Oral hawthorn has only been evaluated in combination with other ingredients; its effect when used alone is unclear.
Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Liraglutide Recombinant on your own; if you are taking Hawthorn for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.
Questions About Hawthorn or Liraglutide Recombinant
These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Hawthorn or Liraglutide Recombinant, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:
- Does Hawthorn Interact With Eliquis? ›
- Can You Take Hawthorn Supplements With Azithromycin (Z-PACK)? ›
- Is Is Hawthorn Safe To Take With Aspirin? Safe To Take With Aspirin? ›
- Can Hawthorn And Labetalol Be Taken Together? ›
Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.
See Every Supplement That Interacts With Liraglutide Recombinant
This page covers Hawthorn only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Liraglutide Recombinant page lists 239 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Siberian Cocklebur (major), Acai (moderate), African Wild Potato (moderate), Agaricus Mushroom (moderate) and Agmatine (moderate).
By severity: 1 major · 208 moderate · 30 minor.
From our pharmacist’s overview on the Liraglutide Recombinant page
“If you take liraglutide (Saxenda), handle this page with real care, because all 239 ingredients on it act on the same thing the drug does, your blood sugar. The one major entry, Siberian cocklebur, has caused severe hypoglycemia, dangerously low blood sugar, in people and should never be combined with a glucose-lowering medicine.”
Reviewed by 2 · Jul 18, 2026
Taking Hawthorn as Part of a Dietary Supplement Product? Check It for Interactions
We hold 2,624 real supplement products containing Hawthorn, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Hawthorn. Even though Hawthorn itself has no known interaction with Liraglutide Recombinant, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Hawthorn and Liraglutide Recombinant Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#113 of 1,452 supplements looked up here in the last 7 days
#344 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Hawthorn reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Hawthorn and Liraglutide Recombinant records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Hawthorn
What is Hawthorn?
- Heart failure symptoms
- High blood pressure
- Chest pain (angina)
- Irregular heartbeat
- Digestive upset
- Anxiety
Hawthorn is a plant traditionally used for heart-related complaints, and some studies suggest it may modestly help symptoms of mild heart failure when added to standard care. However, the evidence is mixed and it should never replace prescribed heart medicines. Always talk to your pharmacist or doctor before using hawthorn, especially if you have a heart condition.
Crataegus monogyna · Rosaceae · Leaves, flowers, and berries (fruit) · Capsules, tablets, standardized extracts, liquid tinctures, teas
An interaction check asks whether these two react with each other — it does not ask whether Hawthorn is a good idea for someone in your situation. Here is what our Hawthorn record says about it on its own.
Hawthorn: dosing
There is no single standard dose of hawthorn that fits everyone. This is especially important if you take heart or blood pressure medicines or have any chronic health condition. Do not assume that more is better.
From our Hawthorn monograph — the full record covers uses, side effects and every documented interaction.
About Liraglutide Injection
What Is Liraglutide Injection Used For?
Brand name: Saxenda
Saxenda is used alongside a reduced-calorie diet and increased physical activity for chronic weight management. It is approved for adults with a BMI of 30 or higher, or a BMI of 27 or higher if they also have at least one weight-related condition such as high blood pressure, type 2 diabetes, or dyslipidemia (abnormal cholesterol or fat levels). It is also approved for adolescents aged 12 and older who weigh more than 60 kg and meet certain BMI thresholds for obesity.
Saxenda should not be used together with other liraglutide-containing products or any other GLP-1 receptor agonist. Its safety and effectiveness in combination with other prescription or over-the-counter weight-loss products have not been established.
Other Drugs & Hawthorn
Browse every other medication we’ve checked against Hawthorn — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
14 interactions
177 interactions
- Diclofenac Sodium ›
- Diltiazem ›
- Nifedipine ›
- Ibuprofen ›
- Aspirin ›
- Naproxen ›
- Minocycline ›
- Propranolol ›
- Verapamil ›
- Diclofenac Potassium ›
- Dipyridamole ›
- Ketoprofen ›
- Sotalol ›
- Bivalirudin ›
- Digoxin ›
- Nicardipine ›
- Timolol ›
- Warfarin Sodium ›
- Acebutolol ›
- Atenolol ›
- Betaxolol ›
- Bromfenac Sodium ›
- Carteolol ›
- Carvedilol ›
- Dabigatran ›
- Diclofenac Epolamine ›
- Felodipine ›
- Iloprost ›
- Labetalol ›
- Metoprolol ›
- Nadolol ›
- Nebivolol ›
- Pindolol ›
- Piroxicam ›
- Streptokinase ›
- Ticlopidine ›
- Treprostinil (oral) ›
- Abciximab ›
- Abrocitinib ›
- Acenocoumarol ›
- Acetylsalicylic Acid ›
- Amlodipine ›
- Amlodipine Benzoate ›
- Amlodipine Besilate ›
- Amlodipine Besylate ›
- Anacaulase-bcdb ›
- Anagrelide ›
- Anisindione ›
- Antithrombin Iii ›
- Apixaban ›
- Argatroban ›
- Bepridil ›
- Betrixaban ›
- Bisoprolol ›
- Cablivi ›
- Cangrelor ›
- Celiprolol ›
- Cilostazol ›
- Clopidogrel ›
- Dalteparin ›
Showing 60 of 177 moderate interactions — see all 177 on the Hawthorn page.
No interaction 2,638 drugs checked — show the list
We also checked Hawthorn against these medications and found no known interaction in our sources. Open any page to confirm.
- Levothyroxine ›
- Methylphenidate ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Ivermectin ›
- Rosuvastatin ›
- Escitalopram ›
- Acetaminophen ›
- Atorvastatin ›
- Docusate ›
- Valacyclovir ›
- Hydroxyurea ›
- Abemaciclib ›
- Methamphetamine ›
- Sumatriptan ›
- Semaglutide ›
- Tirzepatide ›
- Prednisone ›
- Lisdexamfetamine ›
- Bupropion ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Acyclovir ›
- Bendamustine ›
- Amitriptyline ›
- Doxycycline ›
- Methotrexate ›
- Fluoxetine ›
- Lamotrigine ›
- Acetaminophen, Codeine ›
- Amphetamine ›
- Gabapentin ›
- Pregabalin ›
- Dextroamphetamine ›
- Azithromycin ›
- Isotretinoin ›
- Clonazepam ›
- Omeprazole ›
- Methylene Blue ›
- Quetiapine ›
- Duloxetine ›
- Letrozole ›
- Buspirone ›
- Citalopram ›
- Ciprofloxacin ›
- Levothyroxine, Liothyronine ›
- Acetaminophen, Oxycodone ›
- Dapsone ›
- Diazepam ›
- Cyclopentolate ›
- Candesartan Cilexetil ›
- Mannitol ›
- Cephalexin ›
- Roxithromycin ›
- Acetaminophen, Dextromethorphan, Doxylamine ›
- Atorvastatin Calcium ›
- Pegunigalsidase Alfa-iwxj ›
- Acetaminophen, Caffeine, Codeine ›
Showing the 60 most looked-up of 2,638 medications checked with no known interaction — see the full Hawthorn list.
Hawthorn References
The 25 references that drive our Hawthorn monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Tauchert M. Efficacy and safety of crataegus extract WS 1442 in comparison with placebo in patients with chronic stable New York Heart Association class-III heart failure. Am Heart J 2002;143:910-5. PubMed
- Pittler MH, Schmidt K, Ernst E. Hawthorn extract for treating chronic heart failure: meta-analysis of randomized trials. Am J Med 2003;114:665-74.. PubMed
- Chang Q, Zuo Z, Harrison F, Chow MS. Hawthorn. J Clin Pharmacol 2002;42:605-12.
- Holubarsch CJ, Colucci WS, Meinertz T, et al. The efficacy and safety of Crataegus extract WS 1442 in patients with heart failure: the SPICE trial. Eur J Heart Fail 2008;10:1255-63. PubMed
- Pittler MH, Guo R, and Ernst E. Hawthorn extract for treating chronic heart failure. Cochrane.Database.Syst Rev 2008:CD005312. PubMed
- Zick SM, Vautaw BM, Gillespie B, Aaronson KD. Hawthorn Extract Randomized Blinded Chronic Heart Failure (HERB CHF) trial. Eur J Heart Fail. 2009;11:990-99. PubMed
- Werner NS, Duschek S, and Schandry R. D-camphor-crataegus berry extract combination increases blood pressure and cognitive functioning in the elderly - a randomized, placebo controlled double blind study. Phytomedicine. 2009;16:1077-82. PubMed
- Dalli E, Colomer E, Tormos MC, et al. Crataegus laevigata decreases neutrophil elastase and has hypolipidemic effect: a randomized, double-blind, placebo-controlled trial. Phytomedicine. 6-15-2011;18:769-75. PubMed
- Maek-a-nantawat W, Phonrat B, Dhitavat J, et al. Safety and efficacy of CKBM-A01, a Chinese herbal medicine, among asymptomatic HIV patients. Southeast Asian J Trop.Med Public Health 2009;40:494-501.
- Asher GN, Viera AJ, Weaver MA, et al. Effect of hawthorn standardized extract on flow mediated dilation in prehypertensive and mildly hypertensive adults: a randomized, controlled cross-over trial. BMC.Complement Altern.Med 2012;12:26. PubMed
- Walker AF, Marakis G, Simpson E, et al. Hypotensive effects of hawthorn for patients with diabetes taking prescription drugs: a randomised controlled trial. Br J Gen.Pract 2006;56:437-43.
- Daniele C, Mazzanti G, Pittler MH, et al. Adverse-event profile of Crataegus spp.: a systematic review. Drug Saf 2006;29:523-35. PubMed
- Tankanow R, Tamer HR, Streetman DS, et al. Interaction study between digoxin and a preparation of hawthorn (Crataegus oxyacantha). J.Clin.Pharmacol. 2003;43:637-42. DOI
- Tauchert, M., Gildor, A., and Lipinski, J. [High-dose Crataegus extract WS 1442 in the treatment of NYHA stage II heart failure]. Herz 1999;24(6):465-474.
- Horoz, M., Gok, E., Genctoy, G., Ozcan, T., Olmaz, R., Akca, M., Kiykim, A., and Gurses, I. Crataegus orientalis associated multiorgan hypersensitivity reaction and acute renal failure. Intern.Med 2008;47(23):2039-2042. PubMed
- Dalli, E., Valles, J., Cosin-Sales, J., Santos, M. T., Moscardo, A., Milara, J., and Sotillo, J. F. Effects of hawthorn (Crataegus laevigata) on platelet aggregation in healthy volunteers. Thromb.Res 2011;128(4):398-400. PubMed
- Rogov VD. [Toxiderma due to the fruits of the hawthorn]. Vestn Dermatol Venerol 1984;7(7):46-47.
- Loew D, Albrecht M, and Podzuweit H. Efficacy and tolerability of a Hawthorn preparation in patients with heart failure Stage I and II according to NYHA - a surveillance study. Phytomedicine 1996;3(Suppl 1):92.
- Rababa'h AM, Altarabsheh SE, Haddad O, Deo SV, Obeidat Y, Al-Azzam S. Hawthorn Herb Increases the Risk of Bleeding after Cardiac Surgery: An Evidence-Based Approach. Heart Surg Forum 2016;19(4):E175-9. PubMed
- Shatoor AS, Soliman H, Al-Hashem F, Gamal BE, Othman A, El-Menshaw N. Effect of hawthorn (Crataegus aronia syn. Azarolus (L)) on platelet function in albino wistar rats. Thromb Res 2012;130(1):75-80. PubMed
- Vibes J, Lasserre B, Gleye J, Declume C. Inhibition of thromboxane A2 biosynthesis in vitro by the main components of Crataegus oxyacantha (hawthorn) flower heads. Prostaglandins Leukot Essent Fatty Acids 1994;50(4):173-5. PubMed
- Rogers KL, Grice ID, Griffiths LR. Inhibition of platelet aggregation and 5-HT release by extracts of Australian plants used traditionally as headache treatments. Eur J Pharm Sci 2000;9(4):355-63. PubMed
- Zhou CC, Huang XX, Gao PY, et al. Two new compounds from Crataegus pinnatifida and their antithrombotic activities. J Asian Nat Prod Res 2014;16(2):169-74.
- Palmer KG, Lebin JA, Cronin MT, Mazor SS, Burns RA. Crataegus mexicana (Tejocote) Exposure Associated with Cardiotoxicity and a Falsely Elevated Digoxin Level. J Med Toxicol. 2019;15(4):295-298. PubMed
- Espinosa J, Bassett R, Lucerna A, Finn D. Hawthorne root (Crataegus mexicana) toxicity. Am J Emerg Med. 2024;78:242.e5-242.e6. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Liraglutide Recombinant Is Linked to Lower Levels of One Nutrient
Natural Medicines records Liraglutide Recombinant as a medicine that can lower these. This is not an interaction with Hawthorn — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Liraglutide Recombinant nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Hawthorn and Liraglutide Recombinant Together: Common Questions
Is it safe to take Hawthorn with Liraglutide Recombinant?
Do Hawthorn and Liraglutide Recombinant have any of the same side effects?
Are Hawthorn and Liraglutide Recombinant used for the same thing?
How was the Hawthorn and Liraglutide Recombinant combination checked?
Does Hawthorn interact with any other medications?
Does Liraglutide Recombinant interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Still Have a Question About Liraglutide Recombinant and Hawthorn?
Our pharmacists answer your medication & supplement questions — free.
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.