Hawthorn + Atorvastatin
Atorvastatin brand name: Atorvaliq.
We found no known interaction between Hawthorn and Atorvastatin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Hawthorn and Atorvastatin
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Atorvastatin and Hawthorn in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Hawthorn safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Atorvastatin
Interactions in our licensed database are recorded against drug classes, not just single drug names. Atorvastatin is filed under 7 classifications — including hmg-coa reductase inhibitors ("statins"), organic anion-transporting polypeptide substrates (oatp), glucuronidated drugs. Hawthorn has documented interactions with 6 drug classes — the most serious being nitrates (major), phosphodiesterase-5 inhibitors (major) and anticoagulant/antiplatelet drugs (moderate) — and none of Atorvastatin’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Hawthorn Does Interact With Other Medications
Hawthorn has 14 major, 177 moderate known drug interactions in our database — Atorvastatin isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Hawthorn
We haven’t checked that one against Hawthorn yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Hawthorn. Pick one to open its full report.
What Atorvastatin Is Prescribed For, and What Hawthorn Has Been Studied For
These two come up together because they touch the same health topic — not because they do the same job. Atorvastatin is a prescription medicine with approved uses on its FDA label. Hawthorn is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.
Atorvastatin is prescribed for: Atorvastatin is used alongside a healthy diet to lower LDL ("bad") cholesterol, triglycerides (blood fats), and other harmful lipids, while raising HDL ("good") cholesterol. It treats primary hyperlipidemia (high cholesterol), mixed dyslipidemia (mixed abnormal blood fats), hypertriglyceridemia (high triglycerides), and inherited conditions such as heterozygous and homozygous familial hypercholesterolemia — including in children aged 10 and older. Beyond cholesterol control, atorvastatin is used to reduce the risk of heart attack, stroke, revascularization procedures, and angina (chest pain) in adults with coronary heart disease or multiple risk factors for it — including adults with type 2 diabetes who have risk factors for heart disease even without a confirmed heart disease diagnosis.
Hawthorn has been studied for:
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Hyperlipidemia studied, not established Hawthorn has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows
Hawthorn for hyperlipidemia
Although there has been interest in using oral hawthorn for hyperlipidemia, there is insufficient reliable information about the clinical effects of arrhythmia for this condition.
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Angina studied, not established Hawthorn has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows
Hawthorn for angina
It is unclear if oral hawthorn is beneficial in patients with angina.
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Atherosclerosis studied, not established Hawthorn has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows
Hawthorn for atherosclerosis
Although there has been interest in using oral hawthorn for atherosclerosis, there is insufficient reliable information about the clinical effects of arrhythmia for this condition.
Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Atorvastatin on your own; if you are taking Hawthorn for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.
Questions About Hawthorn or Atorvastatin
These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Hawthorn or Atorvastatin, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:
- Does Hawthorn Interact With Eliquis? ›
- Can I Take Ginkgo With Apixaban (Eliquis) and Atorvastatin? ›
- Can You Take Hawthorn Supplements With Azithromycin (Z-PACK)? ›
- Is It Safe to Eat Pomegranate Seeds With Pravastatin? ›
Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.
See Every Supplement That Interacts With Atorvastatin
This page covers Hawthorn only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Atorvastatin page lists 181 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Apple (major), Beer (major), Grapefruit (major) and Green Tea (major).
By severity: 9 major · 136 moderate · 36 minor.
From our pharmacist’s overview on the Atorvastatin page
“Grapefruit is the entry to understand first. Atorvastatin (Atorvaliq) is cleared by an enzyme called CYP3A4, and grapefruit blocks that enzyme, letting statin levels climb along with the risk of side effects like muscle pain.”
Reviewed by 2 · Jul 18, 2026
Taking Hawthorn as Part of a Dietary Supplement Product? Check It for Interactions
We hold 2,624 real supplement products containing Hawthorn, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Hawthorn. Even though Hawthorn itself has no known interaction with Atorvastatin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Hawthorn and Atorvastatin Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#114 of 1,452 supplements looked up here in the last 7 days
#23 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Hawthorn reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Hawthorn and Atorvastatin records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Hawthorn
What is Hawthorn?
- Heart failure symptoms
- High blood pressure
- Chest pain (angina)
- Irregular heartbeat
- Digestive upset
- Anxiety
Hawthorn is a plant traditionally used for heart-related complaints, and some studies suggest it may modestly help symptoms of mild heart failure when added to standard care. However, the evidence is mixed and it should never replace prescribed heart medicines. Always talk to your pharmacist or doctor before using hawthorn, especially if you have a heart condition.
Crataegus monogyna · Rosaceae · Leaves, flowers, and berries (fruit) · Capsules, tablets, standardized extracts, liquid tinctures, teas
An interaction check asks whether these two react with each other — it does not ask whether Hawthorn is a good idea for someone in your situation. Here is what our Hawthorn record says about it on its own.
Hawthorn: dosing
There is no single standard dose of hawthorn that fits everyone. This is especially important if you take heart or blood pressure medicines or have any chronic health condition. Do not assume that more is better.
From our Hawthorn monograph — the full record covers uses, side effects and every documented interaction.
About Atorvastatin
What Is Atorvastatin Used For?
Brand name: Atorvaliq
Atorvastatin is used alongside a healthy diet to lower LDL ("bad") cholesterol, triglycerides (blood fats), and other harmful lipids, while raising HDL ("good") cholesterol. It treats primary hyperlipidemia (high cholesterol), mixed dyslipidemia (mixed abnormal blood fats), hypertriglyceridemia (high triglycerides), and inherited conditions such as heterozygous and homozygous familial hypercholesterolemia — including in children aged 10 and older.
Beyond cholesterol control, atorvastatin is used to reduce the risk of heart attack, stroke, revascularization procedures, and angina (chest pain) in adults with coronary heart disease or multiple risk factors for it — including adults with type 2 diabetes who have risk factors for heart disease even without a confirmed heart disease diagnosis.
Other Drugs & Hawthorn
Browse every other medication we’ve checked against Hawthorn — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
14 interactions
177 interactions
- Diclofenac Sodium ›
- Diltiazem ›
- Nifedipine ›
- Ibuprofen ›
- Aspirin ›
- Naproxen ›
- Minocycline ›
- Propranolol ›
- Verapamil ›
- Diclofenac Potassium ›
- Dipyridamole ›
- Ketoprofen ›
- Sotalol ›
- Bivalirudin ›
- Digoxin ›
- Nicardipine ›
- Timolol ›
- Warfarin Sodium ›
- Acebutolol ›
- Atenolol ›
- Betaxolol ›
- Bromfenac Sodium ›
- Carteolol ›
- Carvedilol ›
- Dabigatran ›
- Diclofenac Epolamine ›
- Felodipine ›
- Iloprost ›
- Labetalol ›
- Metoprolol ›
- Nadolol ›
- Nebivolol ›
- Pindolol ›
- Piroxicam ›
- Streptokinase ›
- Ticlopidine ›
- Treprostinil (oral) ›
- Abciximab ›
- Abrocitinib ›
- Acenocoumarol ›
- Acetylsalicylic Acid ›
- Amlodipine ›
- Amlodipine Benzoate ›
- Amlodipine Besilate ›
- Amlodipine Besylate ›
- Anacaulase-bcdb ›
- Anagrelide ›
- Anisindione ›
- Antithrombin Iii ›
- Apixaban ›
- Argatroban ›
- Bepridil ›
- Betrixaban ›
- Bisoprolol ›
- Cablivi ›
- Cangrelor ›
- Celiprolol ›
- Cilostazol ›
- Clopidogrel ›
- Dalteparin ›
Showing 60 of 177 moderate interactions — see all 177 on the Hawthorn page.
No interaction 2,638 drugs checked — show the list
We also checked Hawthorn against these medications and found no known interaction in our sources. Open any page to confirm.
- Levothyroxine ›
- Methylphenidate ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Ivermectin ›
- Rosuvastatin ›
- Escitalopram ›
- Acetaminophen ›
- Docusate ›
- Valacyclovir ›
- Hydroxyurea ›
- Abemaciclib ›
- Methamphetamine ›
- Sumatriptan ›
- Semaglutide ›
- Tirzepatide ›
- Prednisone ›
- Bupropion ›
- Lisdexamfetamine ›
- Metformin ›
- Amoxicillin ›
- Acyclovir ›
- Lisinopril ›
- Bendamustine ›
- Amitriptyline ›
- Doxycycline ›
- Methotrexate ›
- Fluoxetine ›
- Lamotrigine ›
- Amphetamine ›
- Gabapentin ›
- Pregabalin ›
- Acetaminophen, Codeine ›
- Azithromycin ›
- Dextroamphetamine ›
- Isotretinoin ›
- Clonazepam ›
- Omeprazole ›
- Quetiapine ›
- Methylene Blue ›
- Duloxetine ›
- Letrozole ›
- Buspirone ›
- Citalopram ›
- Ciprofloxacin ›
- Levothyroxine, Liothyronine ›
- Acetaminophen, Oxycodone ›
- Dapsone ›
- Diazepam ›
- Cyclopentolate ›
- Candesartan Cilexetil ›
- Cephalexin ›
- Mannitol ›
- Roxithromycin ›
- Acetaminophen, Dextromethorphan, Doxylamine ›
- Atorvastatin Calcium ›
- Pegunigalsidase Alfa-iwxj ›
- Daptomycin ›
- Acetaminophen, Caffeine, Codeine ›
Showing the 60 most looked-up of 2,638 medications checked with no known interaction — see the full Hawthorn list.
Hawthorn References
The 25 references that drive our Hawthorn monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Tauchert M. Efficacy and safety of crataegus extract WS 1442 in comparison with placebo in patients with chronic stable New York Heart Association class-III heart failure. Am Heart J 2002;143:910-5. PubMed
- Pittler MH, Schmidt K, Ernst E. Hawthorn extract for treating chronic heart failure: meta-analysis of randomized trials. Am J Med 2003;114:665-74.. PubMed
- Chang Q, Zuo Z, Harrison F, Chow MS. Hawthorn. J Clin Pharmacol 2002;42:605-12.
- Holubarsch CJ, Colucci WS, Meinertz T, et al. The efficacy and safety of Crataegus extract WS 1442 in patients with heart failure: the SPICE trial. Eur J Heart Fail 2008;10:1255-63. PubMed
- Pittler MH, Guo R, and Ernst E. Hawthorn extract for treating chronic heart failure. Cochrane.Database.Syst Rev 2008:CD005312. PubMed
- Zick SM, Vautaw BM, Gillespie B, Aaronson KD. Hawthorn Extract Randomized Blinded Chronic Heart Failure (HERB CHF) trial. Eur J Heart Fail. 2009;11:990-99. PubMed
- Werner NS, Duschek S, and Schandry R. D-camphor-crataegus berry extract combination increases blood pressure and cognitive functioning in the elderly - a randomized, placebo controlled double blind study. Phytomedicine. 2009;16:1077-82. PubMed
- Dalli E, Colomer E, Tormos MC, et al. Crataegus laevigata decreases neutrophil elastase and has hypolipidemic effect: a randomized, double-blind, placebo-controlled trial. Phytomedicine. 6-15-2011;18:769-75. PubMed
- Maek-a-nantawat W, Phonrat B, Dhitavat J, et al. Safety and efficacy of CKBM-A01, a Chinese herbal medicine, among asymptomatic HIV patients. Southeast Asian J Trop.Med Public Health 2009;40:494-501.
- Asher GN, Viera AJ, Weaver MA, et al. Effect of hawthorn standardized extract on flow mediated dilation in prehypertensive and mildly hypertensive adults: a randomized, controlled cross-over trial. BMC.Complement Altern.Med 2012;12:26. PubMed
- Walker AF, Marakis G, Simpson E, et al. Hypotensive effects of hawthorn for patients with diabetes taking prescription drugs: a randomised controlled trial. Br J Gen.Pract 2006;56:437-43.
- Daniele C, Mazzanti G, Pittler MH, et al. Adverse-event profile of Crataegus spp.: a systematic review. Drug Saf 2006;29:523-35. PubMed
- Tankanow R, Tamer HR, Streetman DS, et al. Interaction study between digoxin and a preparation of hawthorn (Crataegus oxyacantha). J.Clin.Pharmacol. 2003;43:637-42. DOI
- Tauchert, M., Gildor, A., and Lipinski, J. [High-dose Crataegus extract WS 1442 in the treatment of NYHA stage II heart failure]. Herz 1999;24(6):465-474.
- Horoz, M., Gok, E., Genctoy, G., Ozcan, T., Olmaz, R., Akca, M., Kiykim, A., and Gurses, I. Crataegus orientalis associated multiorgan hypersensitivity reaction and acute renal failure. Intern.Med 2008;47(23):2039-2042. PubMed
- Dalli, E., Valles, J., Cosin-Sales, J., Santos, M. T., Moscardo, A., Milara, J., and Sotillo, J. F. Effects of hawthorn (Crataegus laevigata) on platelet aggregation in healthy volunteers. Thromb.Res 2011;128(4):398-400. PubMed
- Rogov VD. [Toxiderma due to the fruits of the hawthorn]. Vestn Dermatol Venerol 1984;7(7):46-47.
- Loew D, Albrecht M, and Podzuweit H. Efficacy and tolerability of a Hawthorn preparation in patients with heart failure Stage I and II according to NYHA - a surveillance study. Phytomedicine 1996;3(Suppl 1):92.
- Rababa'h AM, Altarabsheh SE, Haddad O, Deo SV, Obeidat Y, Al-Azzam S. Hawthorn Herb Increases the Risk of Bleeding after Cardiac Surgery: An Evidence-Based Approach. Heart Surg Forum 2016;19(4):E175-9. PubMed
- Shatoor AS, Soliman H, Al-Hashem F, Gamal BE, Othman A, El-Menshaw N. Effect of hawthorn (Crataegus aronia syn. Azarolus (L)) on platelet function in albino wistar rats. Thromb Res 2012;130(1):75-80. PubMed
- Vibes J, Lasserre B, Gleye J, Declume C. Inhibition of thromboxane A2 biosynthesis in vitro by the main components of Crataegus oxyacantha (hawthorn) flower heads. Prostaglandins Leukot Essent Fatty Acids 1994;50(4):173-5. PubMed
- Rogers KL, Grice ID, Griffiths LR. Inhibition of platelet aggregation and 5-HT release by extracts of Australian plants used traditionally as headache treatments. Eur J Pharm Sci 2000;9(4):355-63. PubMed
- Zhou CC, Huang XX, Gao PY, et al. Two new compounds from Crataegus pinnatifida and their antithrombotic activities. J Asian Nat Prod Res 2014;16(2):169-74.
- Palmer KG, Lebin JA, Cronin MT, Mazor SS, Burns RA. Crataegus mexicana (Tejocote) Exposure Associated with Cardiotoxicity and a Falsely Elevated Digoxin Level. J Med Toxicol. 2019;15(4):295-298. PubMed
- Espinosa J, Bassett R, Lucerna A, Finn D. Hawthorne root (Crataegus mexicana) toxicity. Am J Emerg Med. 2024;78:242.e5-242.e6. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Atorvastatin Is Linked to Lower Levels of 2 Nutrients
Natural Medicines records Atorvastatin as a medicine that can lower these. This is not an interaction with Hawthorn — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Atorvastatin nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Hawthorn and Atorvastatin Together: Common Questions
Is it safe to take Hawthorn with Atorvastatin?
Are Hawthorn and Atorvastatin used for the same thing?
How was the Hawthorn and Atorvastatin combination checked?
Does Hawthorn interact with any other medications?
Does Atorvastatin interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Still Have a Question About Atorvastatin and Hawthorn?
Our pharmacists answer your medication & supplement questions — free.
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.