Passion Flower - Liraglutide Recombinant Interaction

Interaction Details

Pharmacist Analysis

Passionflower is not known to have many clinically significant drug interactions.

Nevertheless, it has been shown to have sedative effects, which can be additive when used in conjunction with sedative medications (e.g., Benadryl, benzodiazepines, opioids, etc...).

Therefore, we do list interactions between Passionflower and CNS (central nervous system) depressants or other drugs with strong sedative effects.

Additionally, certain constituents of Passionflower (such as apigenin and vitexin) may inhibit certain drug transports, specifically OATP2B1 and OATP1A2.

These are responsible for the uptake of certain drugs and other compounds into the body.

As Passionflower can inhibit these transports, it is possible that it might reduce the bioavailability of drugs that are substrates for these transporters but studies are far from conclusive on the matter.

There is no known drug interaction between Passionflower and the drug in question here, however.

As always, be sure to speak with your doctor before making any changes to your medication regimen.

Liraglutide Recombinant Overview

• Liraglutide injection (Victoza) is used with a diet and exercise program to control blood sugar levels in adults and children 10 years of age and older with type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood) when other medications did not control levels well enough. Liraglutide injection (Victoza) is also used to reduce the risk of a heart attack, stroke, or death in adults with type 2 diabetes mellitus and heart and blood vessel disease. Liraglutide injection (Victoza) is not used to treat type 1 diabetes (condition in which the body does not produce insulin and therefore cannot control the amount of sugar in the blood) or diabetic ketoacidosis (a serious condition that may develop if high blood sugar is not treated) in adults. Liraglutide injection (Saxenda) is used along with a reduced calorie diet and exercise plan to help certain adults and children 12 years of age and older who weigh 132 pounds (60 kg) or more and who are obese or who are overweight and have weight-related medical problems to lose weight and to keep from gaining back that weight. Liraglutide injection (Saxenda) is not used to treat type 2 diabetes. Liraglutide injection is in a class of medications called incretin mimetics. It works by helping the pancreas to release the right amount of insulin when blood sugar levels are high. Insulin helps move sugar from the blood into other body tissues where it is used for energy. Liraglutide injection also slows the emptying of the stomach and may decrease appetite and cause weight loss.

• Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Using medication(s), making lifestyle changes (e.g., diet, exercise, quitting smoking), and regularly checking your blood sugar may help to manage your diabetes and improve your health. This therapy may also decrease your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage (numb, cold legs or feet; decreased sexual ability in men and women), eye problems, including changes or loss of vision, or gum disease. Your doctor and other healthcare providers will talk to you about the best way to manage your diabetes.

Passion Flower - More Interactions

Passion Flower interacts with 814 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.