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Dietary supplement

Agaricus 500 mg Ingredients & Drug Interactions

by Ron Teeguarden's Dragon Herbs

Agaricus 500 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Agaricus 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Agaricus 500 mg is a dietary supplement by Ron Teeguarden's Dragon Herbs with 1 active ingredient. Its ingredients are commonly taken for immune support, general wellness and antioxidant, adjunct interest during cancer care.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Agaricus Mushroom Fruiting Body Extract, Dried Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Agaricus 500 mg by Ron Teeguarden's Dragon Herbs

Ask about any prescription or over-the-counter medication and we check it for interactions with Agaricus 500 mg by Ron Teeguarden's Dragon Herbs — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Agaricus 500 mg by Ron Teeguarden's Dragon Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Oct 1, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains a single active ingredient: agaricus mushroom fruiting body extract in dried powder form, 500 mg per capsule. The inactive ingredients are pullulan polysaccharide (a capsule binder), rice powder, bamboo extract powder, and rice extract blend — standard fillers and flow agents.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Agaricus Mushroom's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: immune-modulating polysaccharides support.
  • We looked for evidence on: Cancer, Chemotherapy-induced adverse effects, Hepatitis B, immune function, infection resistance.
  • The closest evidence on file: Agaricus Mushroom is rated "Insufficient Reliable Evidence To Rate" for Cancer (Natural Medicines).
  • Also on file: Agaricus Mushroom is rated "Insufficient Reliable Evidence To Rate" for Chemotherapy-induced adverse effects, Hepatitis B.

The evidence for agaricus mushroom is not yet established in the data we hold. The supplement has been studied or proposed for allergic rhinitis (hay fever), osteoporosis, cancer, cardiovascular disease, chemotherapy side effects, and Crohn disease, but the research is rated as insufficient to confirm whether it works for any of these uses.

The evidence, ingredient by ingredient Agaricus Mushroom

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Agaricus mushroom is generally well tolerated when taken by mouth, and it's been used as food in some cultures. The most common side effects reported are abdominal discomfort, diarrhea, and nausea.

Rare but serious adverse effects have been reported — including allergic reactions, liver damage, and a lung condition called interstitial lung disease (ILD). Three cases of severe liver damage, including two fatal cases, were reported in women with cancer who were also on chemotherapy and taking agaricus mushroom; one patient also carried hepatitis B virus.

Allergic rashes have also been reported with certain agaricus products. There is not enough safety data to know whether this supplement is safe during pregnancy — the data advises against using it.

The same applies to breastfeeding: there isn't enough information either way, so talk with your doctor or pharmacist for personalized advice before taking it while nursing.

Side effects, ingredient by ingredient Agaricus Mushroom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Agaricus Mushroom.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check with your doctor or pharmacist if you're on any antidiabetes drugs — the supplement may raise your risk of low blood sugar. No other medication interactions are documented in our data for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Agaricus mushroom extract may be of interest if you're exploring traditional supplements, but the evidence for its effectiveness is not yet clear. The main concern is a Moderate risk of low blood sugar if you take diabetes medication — you'll want to clear this with your doctor or pharmacist first.

Avoid it in pregnancy, and talk it over with your healthcare provider before starting if you're breastfeeding or have liver disease.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Agaricus 500 mg, straight from the product label.

Brand Ron Teeguarden's Dragon Herbs
Barcode (UPC) 679372005014
Net contents 100 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jul 25, 2024
DSLD ID 316657
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Agaricus 500 mg by Ron Teeguarden's Dragon Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
33
UPC/BARCODE
679372005014
IngredientAmount% DV
Agaricus Mushroom Fruiting Body Extract, Dried Powder1500 mg--

Other ingredients: Pullulan Polysaccharide, Rice, Powder, Bamboo Extract, Powder, Rice extract Blend

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Agaricus blazei murill, (Most commonly known as Agaricus), is one of the most exciting new herbs on the market today. It contains potent immune-modulating polysaccharides and is extremely safe and effective.

Agaricus 500 mg Each

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Take 3 capsules, 2 times per day or as directed by a healthcare professional.

Precautions

Keep out of the reach of children.

Brand IP Statement(s)

Ron Teeguarden's Dragon Herbs Health Deserves Cultivation

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Agaricus 500 mg by Ron Teeguarden's Dragon Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Agaricus 500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Agaricus 500 mg by Ron Teeguarden's Dragon Herbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container33 Amounts shown are per serving.

Agaricus Mushroom Fruiting Body Extract, Dried Powder

Interacts with
86 drugs
1500 mg per serving Form: Agaricus blazei Mushroom Fruiting Body Extract, Dried, Powder

Agaricus mushroom (often Agaricus blazei/subrufescens) is a culinary and medicinal mushroom studied mostly for possible immune and antioxidant effects...

Agaricus Mushroom Fruiting Body Extract, Dried Powder monograph & interactions

Other (inactive) ingredients: Pullulan Polysaccharide, Rice, Powder, Bamboo Extract, Powder, Rice extract Blend. These complete the product’s ingredient list but are not active constituents.

Interaction report

Agaricus 500 mg by Ron Teeguarden's Dragon Herbs Drug Interactions

Want to check YOUR meds against Agaricus 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Agaricus Mushroom Fruiting Body Extract, Dried Powder 86

Individual Drug Interactions

The ingredients in Agaricus 500 mg interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Agaricus 500 mg interact with drugs. Each result below shows which ingredient is responsible. Agaricus Mushroom Fruiting Body Extract, Dried Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Agaricus 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Agaricus Mushroom Fruiting Body Extract, Dried Powder1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking agaricus mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
In one clinical study in patients with type 2 diabetes who are stabilized on conventional oral hypoglycemic agents, 3 of 29 patients taking an agaricus mushroom extract 500 mg three times daily for 12 weeks reported hypoglycemia, compared to one of 29 patients in the placebo group.

Likelihood Possible Evidence D
Agaricus Mushroom Fruiting Body Extract, Dried Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Agaricus 500 mg, from the product label.

Ron Teeguarden's Dragon Herbs

See all Ron Teeguarden's Dragon Herbs products
Name
Ron Teeguarden's Dragon Herbs
Phone Number
(888) 558-6642
Web Address
www.dragonherbs.com
Pharmacist Counseling Corner

Agaricus 500 mg by Ron Teeguarden's Dragon Herbs: Common Questions

Does Agaricus 500 mg by Ron Teeguarden's Dragon Herbs interact with any medications?
Yes. Based on its ingredients, Agaricus 500 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Agaricus 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What are the most common side effects?
Agaricus mushroom is generally well tolerated, but some people report abdominal discomfort, diarrhea, and nausea. These are the most commonly reported mild effects.
Has agaricus been proven to work for cancer?
The evidence for agaricus in cancer is rated insufficient in the data we hold — there isn't enough reliable research to confirm whether it works. Additionally, three serious cases of liver damage occurred in cancer patients taking chemotherapy and agaricus mushroom together, so this combination needs careful medical oversight.
Can I take this while I'm breastfeeding?
There isn't enough safety data to know either way. Talk with your doctor or pharmacist before using this supplement while breastfeeding — they can help you decide whether it's right for your situation.
Is it safe during pregnancy?
No — there isn't enough safety data, so it's best to avoid supplement doses of agaricus mushroom during pregnancy. Check with your doctor or pharmacist if you're planning to become pregnant or are already pregnant.
What does agaricus mushroom do?
It's been studied for allergic rhinitis (hay fever), osteoporosis, cancer, heart disease, chemotherapy side effects, and Crohn disease. However, the evidence isn't established yet for any of these uses in the data we hold.
Are there any serious side effects I should watch for?
Serious adverse effects are rare but have been reported — including allergic reactions, liver damage, and a lung inflammation called interstitial lung disease (ILD). Three cases of severe liver damage occurred in women with cancer on chemotherapy who also took agaricus mushroom, including two fatal cases. Stop the supplement and contact your doctor right away if you develop unusual fatigue, dark urine, or yellowing of the skin or eyes.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Agaricus 500 mg label
Go deeper

The Full Monographs Behind Agaricus 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Agaricus Mushroom

Interacts with 86 drugs

Agaricus mushroom (often Agaricus blazei/subrufescens) is a culinary and medicinal mushroom studied mostly for possible immune and antioxidant effects. The human evidence is limited and not...

Read the full Agaricus Mushroom monograph →
Sources

Sources & How We Checked

Agaricus 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Agaricus Mushroom 5 references
  1. Hsu CH, Liao YL, Lin SC, et al. The mushroom Agaricus Blazei Murill in combination with metformin and gliclazide improves insulin resistance in type 2 diabetes: a randomized, double-blinded, and placebo-controlled clinical trial. J Altern Complement Med 2
  2. Mukai H, Watanabe T, Ando M, Katsumata N. An alternative medicine, Agaricus blazei, may have induced severe hepatic dysfunction in cancer patients. Jpn J Clin Oncol 2006;36:808-10. PubMed
  3. Ohno S, Sumiyoshi Y, Hashine K, et al. Phase I clinical study of the dietary supplement, Agaricus blazei Murill, in cancer patients in remission. Evid Based Complement Alternat Med 2011, doi 10.1155/2011/192381.
  4. Suehiro M, Katoh N, Kishimoto S. Chelitis due to Agaricus blazei Murill mushroom extract. Contact Dermatitis 2007;56(5):293-4.
  5. Iwai N, Okuda T, Sawada R, et al. Interstitial lung disease associated with Agaricus blazei Murill in a patient with pancreatic ductal adenocarcinoma receiving gemcitabine-based therapy. Case Rep Gastroenterol 2022;16(1):229-234.

See these in context on the Agaricus Mushroom monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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