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Dietary supplement

Agaricus Mushroom 450 mg 5:1 Extract Ingredients & Drug Interactions

by TerraVita Premium Collection

Agaricus Mushroom 450 mg 5:1 Extract label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Agaricus Mushroom 450 mg 5:1 Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Agaricus Mushroom 450 mg 5:1 Extract is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for immune support, general wellness and antioxidant, adjunct interest during cancer care.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Agaricus Mushroom Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Agaricus Mushroom 450 mg 5:1 Extract by TerraVita Premium Collection

Ask about any prescription or over-the-counter medication and we check it for interactions with Agaricus Mushroom 450 mg 5:1 Extract by TerraVita Premium Collection — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Agaricus Mushroom 450 mg 5:1 Extract by TerraVita Premium Collection

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: agaricus mushroom extract at 450 mg in a 5:1 concentrated form, which means the extract is made from five parts of raw mushroom material. The capsule also contains gelatin and water as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Agaricus Mushroom product and its label doesn't state a use — see Agaricus Mushroom's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for agaricus mushroom is not established in our data. We hold insufficient reliable evidence to rate it for hay fever, osteoporosis, cancer, heart disease, chemotherapy side effects, or Crohn disease.

If you're considering this product for a specific condition, talk with your pharmacist about what the broader research shows.

The evidence, ingredient by ingredient Agaricus Mushroom

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Agaricus mushroom is generally well tolerated when taken by mouth. The most common side effects are abdominal discomfort, diarrhea, and nausea.

Rare but serious adverse effects including allergic reactions, liver damage, and interstitial lung disease (a type of lung injury) have been reported. Three cases of severe liver damage occurred in women with ovarian or breast cancer who were undergoing chemotherapy and taking agaricus mushroom at the same time.

During pregnancy, there isn't enough safety data, so the evidence advises against supplement doses. The same applies to breastfeeding — avoid supplement doses while nursing.

Talk with your doctor or pharmacist if you are pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Agaricus Mushroom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Agaricus Mushroom.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, check whether you're on any antidiabetes medications — insulin, metformin, sulfonylureas, or others. The documented interaction is moderate severity.

If you take diabetes drugs, ask your pharmacist to run your specific medications through the checker on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you take diabetes medication, check with your pharmacist before starting — there's a moderate risk of low blood sugar. The supplement is generally well tolerated at typical doses, but serious liver injury and lung damage have been reported rarely.

Long-term safety data are limited. Have a conversation with your pharmacist or doctor about whether this product is right for you, especially if you have a history of liver disease or are on other medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Agaricus Mushroom 450 mg 5:1 Extract, straight from the product label.

Brand TerraVita Premium Collection
Barcode (UPC) 064435208721
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Mar 22, 2023
DSLD ID 289335
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Agaricus Mushroom 450 mg 5:1 Extract by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
100
UPC/BARCODE
064435208721
IngredientAmount% DV
Agaricus Mushroom Extract450 mg--

Other ingredients: Gelatin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

Copyright 2017 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Suggested/Recommended/Usage/Directions

Directions Take 1 capsule, 3 times daily, with meals.

General Statements

TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.

Please recycle!

FDA Disclaimer Statement

Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Agaricus Mushroom 450 mg 5:1 Extract by TerraVita Premium Collection label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Agaricus Mushroom 450 mg 5:1 Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Agaricus Mushroom 450 mg 5:1 Extract by TerraVita Premium Collection

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Agaricus Mushroom Extract

Interacts with
86 drugs
450 mg per serving

Agaricus mushroom (often Agaricus blazei/subrufescens) is a culinary and medicinal mushroom studied mostly for possible immune and antioxidant effects...

Agaricus Mushroom Extract monograph & interactions

Other (inactive) ingredients: Gelatin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Agaricus Mushroom 450 mg 5:1 Extract by TerraVita Premium Collection Drug Interactions

Want to check YOUR meds against Agaricus Mushroom 450 mg 5:1 Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Agaricus Mushroom Extract 86

Individual Drug Interactions

The ingredients in Agaricus Mushroom 450 mg 5:1 Extract interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Agaricus Mushroom 450 mg 5:1 Extract interact with drugs. Each result below shows which ingredient is responsible. Agaricus Mushroom Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Agaricus Mushroom 450 mg 5:1 Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Agaricus Mushroom Extract1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking agaricus mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
In one clinical study in patients with type 2 diabetes who are stabilized on conventional oral hypoglycemic agents, 3 of 29 patients taking an agaricus mushroom extract 500 mg three times daily for 12 weeks reported hypoglycemia, compared to one of 29 patients in the placebo group.

Likelihood Possible Evidence D
Agaricus Mushroom Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Agaricus Mushroom 450 mg 5:1 Extract, from the product label.

TerraVita Premium Collection

See all TerraVita Premium Collection products
Name
TerraVita Fine Whole Herbs
City
Brampton
State
Ontario
Pharmacist Counseling Corner

Agaricus Mushroom 450 mg 5:1 Extract by TerraVita Premium Collection: Common Questions

Does Agaricus Mushroom 450 mg 5:1 Extract by TerraVita Premium Collection interact with any medications?
Yes. Based on its ingredients, Agaricus Mushroom 450 mg 5:1 Extract has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Agaricus Mushroom 450 mg 5:1 Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What side effects might I notice if I take this?
Most people who take agaricus mushroom orally experience mild side effects like stomach discomfort, diarrhea, or nausea. Serious reactions — allergic rash, liver damage, or lung injury — are rare but have been reported in the medical literature. Stop and contact your doctor if you develop unusual symptoms.
Can I take this if I'm pregnant?
There isn't enough safety data during pregnancy, so the evidence advises against it. Talk with your doctor before taking any supplement while pregnant.
Can I take this while breastfeeding?
No — there isn't enough safety data while breastfeeding, so it's best to avoid supplement doses. Speak with your pharmacist or doctor about timing if you're nursing.
Does agaricus mushroom actually work for any of these conditions?
We don't have reliable evidence to say whether it works for hay fever, osteoporosis, cancer, heart disease, chemotherapy side effects, or Crohn disease. If you're interested in this supplement for a specific health concern, ask your pharmacist what the research currently shows.
What is a 5:1 extract?
A 5:1 extract means the product was made by concentrating five pounds of raw mushroom material down to one pound of extract. It's a more concentrated form than whole dried mushroom.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Agaricus Mushroom 450 mg 5:1 Extract is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Agaricus Mushroom 450 mg 5:1 Extract label
Go deeper

The Full Monographs Behind Agaricus Mushroom 450 mg 5:1 Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Agaricus Mushroom

Interacts with 86 drugs

Agaricus mushroom (often Agaricus blazei/subrufescens) is a culinary and medicinal mushroom studied mostly for possible immune and antioxidant effects. The human evidence is limited and not...

Read the full Agaricus Mushroom monograph →
Sources

Sources & How We Checked

Agaricus Mushroom 450 mg 5:1 Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Agaricus Mushroom 5 references
  1. Hsu CH, Liao YL, Lin SC, et al. The mushroom Agaricus Blazei Murill in combination with metformin and gliclazide improves insulin resistance in type 2 diabetes: a randomized, double-blinded, and placebo-controlled clinical trial. J Altern Complement Med 2
  2. Mukai H, Watanabe T, Ando M, Katsumata N. An alternative medicine, Agaricus blazei, may have induced severe hepatic dysfunction in cancer patients. Jpn J Clin Oncol 2006;36:808-10. PubMed
  3. Ohno S, Sumiyoshi Y, Hashine K, et al. Phase I clinical study of the dietary supplement, Agaricus blazei Murill, in cancer patients in remission. Evid Based Complement Alternat Med 2011, doi 10.1155/2011/192381.
  4. Suehiro M, Katoh N, Kishimoto S. Chelitis due to Agaricus blazei Murill mushroom extract. Contact Dermatitis 2007;56(5):293-4.
  5. Iwai N, Okuda T, Sawada R, et al. Interstitial lung disease associated with Agaricus blazei Murill in a patient with pancreatic ductal adenocarcinoma receiving gemcitabine-based therapy. Case Rep Gastroenterol 2022;16(1):229-234.

See these in context on the Agaricus Mushroom monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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