Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Alpha Energy Ingredients & Drug Interactions

by Chemical Free Body

Alpha Energy label
See full label image
Capsule Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Alpha Energy against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Alpha Energy is a dietary supplement by Chemical Free Body with 8 active ingredients. Its ingredients are commonly taken for stress and anxiety, sleep problems, fatigue and low energy.Based on those ingredients, 1,485 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Ashwagandha root extract, Sea Buckthorn extract, Tribulus terrestris fruit extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Alpha Energy by Chemical Free Body

Ask about any prescription or over-the-counter medication and we check it for interactions with Alpha Energy by Chemical Free Body — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Alpha Energy by Chemical Free Body

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 8 active ingredients.
  • “Proprietary Herbal Extract Blend” is a proprietary blend — the label gives one combined amount (1,710 mg) without saying how much of each component you get.

Alpha Energy contains eight ingredients, including a proprietary herbal extract blend plus seven individual herbal extracts. The active ingredients are ashwagandha root extract (traditionally used for stress and sleep), Mucuna pruriens (a plant containing the compound levodopa), maca root extract, tribulus terrestris fruit extract, avena sativa extract (oats), muira puama bark extract, catuaba bark extract, and sea buckthorn extract.

The capsules themselves are made from vegetable material.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: pre and post workout energy, strength and stamina.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Exercise-induced muscle soreness, Fatigue, Chronic fatigue syndrome (CFS), endurance — and 3 related terms.
  • The closest evidence on file: Tribulus is rated "Possibly Ineffective" for Athletic performance (Natural Medicines).
  • Also on file: Tribulus is rated "Insufficient Reliable Evidence To Rate" for Chronic fatigue syndrome (CFS), Exercise-induced muscle damage.
  • Also on file: Maca is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Chronic fatigue syndrome (CFS), Fatigue.

The evidence for this product is mixed and incomplete. Ashwagandha is possibly effective for insomnia, anxiety, stress, and generalized anxiety disorder based on available data, though evidence for bipolar disorder is insufficient.

Tribulus is possibly effective for sexual dysfunction but possibly ineffective for athletic performance; evidence for other uses is insufficient. Avena sativa (oats) is likely effective for lowering cholesterol and supporting heart health.

For the other ingredients — maca, muira puama, catuaba, and sea buckthorn — either the evidence is insufficient to rate their effectiveness or, in catuaba's case, no effectiveness data are on file. We hold no effectiveness data for the proprietary herbal extract blend itself.

The evidence, ingredient by ingredient Ashwagandha Maca Tribulus Oats Muira Puama Catuaba Sea Buckthorn Cowhage

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 8 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 8 of 8.
  • General safety write-ups exist for 8 of 8.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Ashwagandha is generally well tolerated short-term in healthy adults, though quality and long-term safety data are limited. The most common side effects are diarrhea, gastrointestinal upset, nausea, and vomiting — though these are uncommon at typical doses.

Rare but serious adverse effects include liver damage (hepatitis, liver failure) and a blood vessel condition called reversible cerebral vasoconstriction syndrome with bleeding. Mucuna pruriens is generally well tolerated but contains an active compound (levodopa) and should be used with professional guidance; oral side effects include diarrhea, flatulence, and mucosal irritation.

Insomnia was reported in about 3% of patients in one study. Tribulus is often well tolerated short-term, though quality and long-term data are limited; gastrointestinal effects and rare serious effects (liver and kidney injury, seizures) have been reported.

Avena sativa (oats) is well tolerated; the most common effects are bloating, flatulence, and abdominal distension from the fiber content, which usually subside with continued use. Sea buckthorn is generally well tolerated but may cause yellow skin staining at high doses.

Maca, muira puama, and catuaba have limited human safety data. Regarding pregnancy: ashwagandha, maca, tribulus, muira puama, and catuaba should be avoided during pregnancy due to insufficient safety data or hormone concerns.

Avena sativa as a food is likely safe in pregnancy, but concentrated supplements are less studied. Sea buckthorn food amounts are likely fine; supplement doses need caution and a doctor's input.

For breastfeeding: ashwagandha, maca, tribulus, muira puama, and catuaba lack adequate safety data and should be avoided. Mucuna pruriens should be avoided because levodopa can lower prolactin levels and reduce milk supply.

Avena sativa as a food is generally safe; concentrated supplements are less studied. Sea buckthorn supplement use while nursing requires caution and medical advice.

Side effects, ingredient by ingredient Ashwagandha Maca Tribulus Oats Muira Puama Catuaba Sea Buckthorn Cowhage

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 5 of the 8 matched ingredients can interact with medications — Tribulus, Sea Buckthorn, Oats, Ashwagandha, Cowhage.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; lithium; Parkinson's medications.
  • For scale: 1,486 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before using Alpha Energy if you take: methyldopa or non-selective MAOIs (Major risk from Mucuna pruriens), levodopa (Major risk), antihypertensive drugs or blood pressure medications (Moderate risk from ashwagandha, tribulus, and sea buckthorn), diabetes medications or insulin (Moderate risk from ashwagandha, tribulus, avena sativa, and mucuna pruriens), benzodiazepines like diazepam or clonazepam (Moderate risk from ashwagandha), antipsychotic drugs, tricyclic antidepressants, thyroid hormones, immunosuppressants, or blood thinners and antiplatelet drugs like aspirin (Moderate risk from various ingredients). Also ask about any drugs that are toxic to the liver or any anesthetics you may need.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

Alpha Energy is built on herbal ingredients with some research backing — ashwagandha for stress and sleep, tribulus for sexual function, and oats for cholesterol — but several of them interact with common medications, including some serious interactions with blood pressure drugs, diabetes drugs, and psychiatric medications. If you take any prescription medication, especially for blood pressure, diabetes, mood, or blood thinning, run your complete medication list through our checker before you start.

Talk to your pharmacist to make sure this product is right for your personal health situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 8 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Alpha Energy, straight from the product label.

Brand Chemical Free Body
Barcode (UPC) 860004002864
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2022
DSLD ID 271782
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Alpha Energy by Chemical Free Body, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
30
UPC/BARCODE
860004002864
IngredientAmount% DV
Proprietary Herbal Extract Blend1710 mg--
Ashwagandha root extract0 NP--
Mucuna pruriens675 mg--
Maca root extract0 NP--
Tribulus terrestris fruit extract0 NP--
Avena sativa extract0 NP--
Muira Puama Bark Extract0 NP--
Catuaba bark extract0 NP--
Sea Buckthorn extract0 NP--

Other ingredients: Vegetable Capsules

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Alpha energy combines the most powerful herbs on earth making it the ultimate pre & post workout booster. Feels like 18 again! Better pumps, less fatigue, increase strength and stamina while enhancing libido naturally and safely.

NOSG Naturally Occurring Standards Group Vegan

Non-GMO Gluten-free

Boost, burn & recover

No magnesium stearate, no silicon dioxide, no dicalcium phosphate

Seals/Symbols

NOSG Naturally Occurring Standards Group

Made in the USA

Suggested/Recommended/Usage/Directions

Suggested use: Adults take 3 capsules daily before, during or after meals.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Please recycle

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Alpha Energy by Chemical Free Body label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Alpha Energy label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Alpha Energy by Chemical Free Body

These are the 8 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Mucuna pruriens

Interacts with
193 drugs
675 mg per serving

Cowhage (Mucuna pruriens) is a tropical legume best known as a natural source of L-dopa, the compound the body turns into dopamine. It is most studied...

Mucuna pruriens monograph & interactions

Other (inactive) ingredients: Vegetable Capsules. These complete the product’s ingredient list but are not active constituents.

Interaction report

Alpha Energy by Chemical Free Body Drug Interactions

Want to check YOUR meds against Alpha Energy?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,485Drugs
17 Major 1,066 Moderate 402 Minor

Ingredients driving the most interactions

Ashwagandha root extract 1,372
Sea Buckthorn extract 289
Tribulus terrestris fruit extract 259
Mucuna pruriens 193
Avena sativa extract 86

Individual Drug Interactions

The ingredients in Alpha Energy interact with 1,485 drugs. Click any drug to see the details.

5 of the 8 ingredients in Alpha Energy interact with drugs. Each result below shows which ingredient is responsible. Ashwagandha root extract Sea Buckthorn extract Tribulus terrestris fruit extract Mucuna pruriens Avena sativa extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Alpha Energy with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Ashwagandha root extract10 drug types · 1,372 drugs

Antidiabetes Drugs

Theoretically, taking ashwagandha with antidiabetes drugs might increase the risk of hypoglycemia.
There is preliminary clinical evidence suggesting that ashwagandha might lower blood glucose levels. Theoretically, ashwagandha might have additive effects when used with antidiabetes drugs and increase the risk of hypoglycemia.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Animal research suggests that ashwagandha might lower systolic and diastolic blood pressure. Theoretically, ashwagandha might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.

Likelihood Possible Evidence D
Benzodiazepines

Theoretically, taking ashwagandha might increase the sedative effects of benzodiazepines.
There is preliminary evidence that ashwagandha might have an additive effect with diazepam (Valium) and clonazepam (Klonopin). This may also occur with other benzodiazepines.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Ashwagandha seems to have sedative effects. Theoretically, this may potentiate the effects of barbiturates, other sedatives, and anxiolytics.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Ashwagandha has been linked to cases of acute hepatitis, liver failure, hepatic encephalopathy, autoimmune hepatitis, the need for liver transplantation, and death due to liver failure.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, taking ashwagandha might decrease the effects of immunosuppressants.
Ashwagandha has demonstrated immunostimulant effects in humans. Animal research has shown that ashwagandha can attenuate the immunosuppression caused by cyclophosphamide.

Likelihood Possible Evidence D
Thyroid Hormone

Ashwagandha might increase the effects and adverse effects of thyroid hormone.
Concomitant use of ashwagandha with thyroid hormones may cause additive therapeutic and adverse effects. Preliminary clinical research and animal studies suggest that ashwagandha boosts thyroid hormone synthesis and secretion. In one clinical study, ashwagandha increased triiodothyronine (T3) and thyroxine (T4) levels by 41.5% and 19.6%, respectively, and reduced serum TSH levels by 17.4% from baseline in adults with subclinical hypothyroidism.

Likelihood Probable Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, ashwagandha might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that ashwagandha extract induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that ashwagandha extract induces CYP3A4 enzymes.

Likelihood Possible Evidence D
Serotonergic Drugs

Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors. However, there is no evidence to suggest that ashwagandha increases the risk of serotonin-related effects, and there have been no published case reports of serotonin syndrome when combined with other serotonergic drugs. Nevertheless, due to the lack of extensive studies on the matter and the fact that ashwagandha appears to affect serotonergic pathways, it would be prudent to exercise caution when combining it with drugs that affect serotonin. [References: - Effects of Withania somnifera (Ashwaga ndha) on Stress and the Stress-Related Neuropsychiatric Disorders Anxiety, Depression, and Insomnia. Curr Neuropharmacol. 2021 Sep 14; 19: 1468–1495. - A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573577/]

Likelihood Possible Evidence C
Ashwagandha root extract full monograph & interactions

Sea Buckthorn extract2 drug types · 289 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, sea buckthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Clinical research suggests that sea buckthorn fruit extracts can inhibit platelet aggregation and adhesion to collagen and fibrinogen.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, taking sea buckthorn with antihypertensive drugs might increase the risk of hypotension.
Taking sea buckthorn appears to reduce blood pressure in some patients.

Likelihood Possible Evidence D
Sea Buckthorn extract full monograph & interactions

Tribulus terrestris fruit extract3 drug types · 259 drugs

Antidiabetes Drugs

Taking tribulus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that Tribulus can lower blood glucose levels in adults with type 2 diabetes who are taking antidiabetes medications.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, taking tribulus with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that tribulus can lower blood pressure by inhibiting angiotensin-converting enzyme (ACE). Tribulus has also demonstrated hypotensive effects in pre-hypertensive adults.

Likelihood Possible Evidence D
Lithium

Theoretically, tribulus might increase the levels and clinical effects of lithium.
Tribulus is thought to have diuretic properties. Due to these potential diuretic effects, tribulus might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Tribulus terrestris fruit extract full monograph & interactions

Mucuna pruriens8 drug types · 193 drugs

Levodopa

Concomitant use can increase the risk of levodopa-related adverse effects.
Cowhage contains levodopa. Some cowhage products have been standardized to contain 75-400 mg of levodopa per dose.

Likelihood Likely Evidence D
Methyldopa (Aldomet)

Theoretically, concomitant use of cowhage and methyldopa might increase the risk of hypotension.
Cowhage contains levodopa. Use of levodopa with methyldopa might cause additive hypotension. In addition, methyldopa may inhibit peripheral decarboxylation of levodopa and increase levodopa levels in the central nervous system; avoid using.

Likelihood Probable Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Cowhage contains levodopa. Use of levodopa with non-selective MAOIs might cause hypertensive crisis. However, this interaction has not been reported with MAO-B selective inhibitors such as selegiline.

Likelihood Probable Evidence D
Anesthesia

Theoretically, concomitant use of cowhage and anesthesia might increase the risk of arrhythmias.
Cowhage contains levodopa. Use of levodopa with cyclopropane or halogenated hydrocarbon anesthesia has led to arrhythmias. Other anesthetics have not been implicated. Use other anesthetics in patients taking cowhage or tell patients to stop taking cowhage at least 2 weeks before surgery.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of cowhage and antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that cowhage might have hypoglycemic effects.

Likelihood Possible Evidence D
Antipsychotic Drugs

Theoretically, use of cowhage might decrease the clinical effects of antipsychotic drugs.
Cowhage contains levodopa. Use of levodopa might counteract the antidopaminergic effects of antipsychotic medications.

Likelihood Possible Evidence D
Guanethidine (Ismelin)

Theoretically, concomitant use of cowhage and guanethidine might increase the risk of hypotension.
Cowhage contains levodopa. Use of levodopa with guanethidine might cause additive hypotension; avoid using.

Likelihood Probable Evidence D
Tricyclic Antidepressants (Tcas)

Theoretically, use of TCAs might reduce the levels and clinical effects of cowhage.
Cowhage contains levodopa. Use of TCAs might reduce the absorption of levodopa. Some case reports describe patients that developed hypertension and dyskinesia when taking both levodopa and TCAs.

Likelihood Possible Evidence D
Mucuna pruriens full monograph & interactions

Avena sativa extract2 drug types · 86 drugs

Antidiabetes Drugs

Theoretically, oats may have additive effects with antidiabetic agents and might increase the risk of hypoglycemia.
Consuming oats can decrease blood glucose in patients with diabetes. In those who require insulin, taking oats 100 grams daily for 2 days reduces the insulin dose required to achieve metabolic control.

Likelihood Possible Evidence D
Insulin

Concomitant use of oats and insulin might increase the risk of hypoglycemia.
In patients with insulin-dependent type 2 diabetes, taking oats 100 grams daily for 2 days reduces the insulin dose required to achieve metabolic control.

Likelihood Possible Evidence B
Avena sativa extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Alpha Energy, from the product label.

Chemical Free Body

See all Chemical Free Body products
Name
Chemical Free Body LLC.
Street Address
16869 SW 65th Ave. #158
City
Lake Oswego
State
OR
ZipCode
97035
Phone Number
1 888-368-9898
Web Address
www.chemicalfreebody.com
Pharmacist Counseling Corner

Alpha Energy by Chemical Free Body: Common Questions

Does Alpha Energy by Chemical Free Body interact with any medications?
Yes. Based on its ingredients, Alpha Energy has a known interaction with 1,485 medications, including 17 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Alpha Energy contains 8 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is ashwagandha in this product supposed to do?
Ashwagandha is included for stress, anxiety, and sleep — the evidence shows it's possibly effective for insomnia, generalized anxiety disorder, and stress management. Long-term safety data are limited, though, and it's generally well tolerated short-term in healthy adults.
Does this product work for energy?
The product name is Alpha Energy, but the ingredients aren't specifically rated for energy or fatigue in our data. Ashwagandha may help with stress and sleep, and oats support heart health, but we don't have effectiveness data for an energy claim.
Can I take this if I'm pregnant?
No — several of the active ingredients (ashwagandha, maca, tribulus, muira puama, and catuaba) should be avoided during pregnancy because safety data are insufficient or there are concerns about hormone effects. If you're planning to become pregnant or are already pregnant, talk with your doctor before using this product.
Can I take this while breastfeeding?
Most of the active ingredients lack adequate safety data for nursing and should be avoided — this includes ashwagandha, maca, tribulus, muira puama, and catuaba. Mucuna pruriens should also be avoided because it can lower prolactin and reduce milk supply. If you're breastfeeding, ask your pharmacist or doctor first.
What are the most common side effects?
Ashwagandha may cause diarrhea, gastrointestinal upset, nausea, and vomiting, though these are uncommon at typical doses. Oats can cause bloating, flatulence, and abdominal distension from the fiber, which usually improve with continued use. Mucuna pruriens may cause diarrhea, flatulence, and mucosal irritation.
Is this product safe for long-term use?
Quality and long-term safety data are limited for most of the ingredients — ashwagandha, tribulus, and sea buckthorn all carry notes that long-term safety is not well established. Stick with short-term use unless your doctor or pharmacist advises otherwise and monitors you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Alpha Energy label
Go deeper

The Full Monographs Behind Alpha Energy’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Ashwagandha

Interacts with 1,372 drugs

Ashwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, though the evidence is still limited. It is generally w...

Read the full Ashwagandha monograph → Herb & supplement monograph

Maca

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire and some menopause symptoms, but the evide...

Read the full Maca monograph → Herb & supplement monograph

Tribulus

Interacts with 259 drugs

Tribulus is a plant supplement most often marketed to boost libido, testosterone, and athletic performance, but the human evidence behind these claims is weak and inconsistent. It is general...

Read the full Tribulus monograph → Herb & supplement monograph

Oats

Interacts with 86 drugs

Oats are a well-studied whole grain whose soluble fiber (beta-glucan) can help lower cholesterol and support heart health when eaten regularly. As a food, oats are safe for most people, and...

Read the full Oats monograph → Herb & supplement monograph

Muira Puama

Muira puama is a Brazilian plant traditionally used as an aphrodisiac and general tonic, often nicknamed 'potency wood.' Human research is very limited, so its benefits are not well proven,...

Read the full Muira Puama monograph → Herb & supplement monograph

Catuaba

Catuaba is a Brazilian herbal bark long used as a traditional aphrodisiac and energy tonic, but there is very little reliable human research to show it works for any health condition. Qualit...

Read the full Catuaba monograph → Herb & supplement monograph

Sea Buckthorn

Interacts with 289 drugs

Sea buckthorn is a berry-bearing shrub rich in vitamins, carotenoids, and fatty acids that people use for skin, eye, digestive, and heart health. Early research is promising for a few uses l...

Read the full Sea Buckthorn monograph → Herb & supplement monograph

Cowhage

Interacts with 193 drugs

Cowhage (Mucuna pruriens) is a tropical legume best known as a natural source of L-dopa, the compound the body turns into dopamine. It is most studied for Parkinson's disease symptoms and ma...

Read the full Cowhage monograph →
Sources

Sources & How We Checked

Alpha Energy's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 77 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ashwagandha 32 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Upton R, ed. Ashwagandha Root (Withania somnifera): Analytical, quality control, and therapuetic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia 2000:1-25.
  3. Davis L, Kuttan G. Effect of Withania somnifera on cyclophosphamide-induced urotoxicity. Cancer Lett 2000;148:9-17. PubMed
  4. Davis L, Kuttan G. Suppressive effect of cyclophosphamide-induced toxicity by Withania somnifera extract in mice. J Ethnopharmacol 1998;62:209-14. PubMed
  5. Mishra LC, Singh BB, Dagenais S. Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review. Altern Med Rev 2000;5:334-46. DOI
  6. Andallu B, Radhika B. Hypoglycemic, diuretic and hypocholesterolemic effect of winter cherry (Withania somnifera, Dunal) root. Indian J Exp Biol 2000;38:607-9.
  7. Kulkarni RR, Patki PS, Jog VP, et al. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol 1991;33:91-5. PubMed
  8. Ahumada F, Aspee F, Wikman G, Hancke J. Withania somnifera exract. Its effects on arterial blood pressure in anaesthetized dogs. Phytother Res 1991;5:111-14.
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Cowhage 12 references
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Maca 1 reference
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Tribulus 10 references
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Oats 13 references
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Sea Buckthorn 7 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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