Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor Ingredients & Drug Interactions

by Ee Essential elements

Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor label
See full label image
Gummy Or Jelly Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor is a dietary supplement by Ee Essential elements with 4 active ingredients. Its ingredients are commonly taken for treating or preventing b12 deficiency, pernicious anemia, low energy and fatigue.Based on those ingredients, 2,063 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Sodium, Apple Cider Vinegar. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor by Ee Essential elements

Ask about any prescription or over-the-counter medication and we check it for interactions with Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor by Ee Essential elements — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor by Ee Essential elements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product has three active ingredients. Vitamin B12 supports nerve and blood cell health and is used to treat B12 deficiency.

Apple cider vinegar is added for its traditional use, though the evidence for its effects is not yet established in our data. Sodium is included as a mineral component, though in supplement form it should be used with caution given dietary sodium intake.

The remaining ingredients are inactive — fillers, binders, and flavoring agents like tapioca fiber syrup, pectin, citric acid, malic acid, stevia, and beet powder that make the gummy form and taste.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Constipation — rated "Effective" (Black Psyllium) (Natural Medicines).
  • On file: Imerslund-Grasbeck disease — rated "Effective" (Vitamin B12) (Natural Medicines).
  • On file: Vitamin B12 deficiency — rated "Effective" (Vitamin B12) (Natural Medicines).
  • On file: Coronary heart disease (CHD) — rated "Likely Effective" (Black Psyllium) (Natural Medicines).
  • On file: Cyanide poisoning — rated "Likely Effective" (Vitamin B12) (Natural Medicines).

Vitamin B12 in this product is effective for treating B12 deficiency and possibly effective for canker sores and nerve pain (postherpetic neuralgia). For apple cider vinegar, the evidence isn't established in our data — claims about acne, athletic performance, cognitive function, dental plaque, mood, and skin conditions (eczema) lack reliable evidence.

Sodium's effectiveness is rated as likely effective for cystic fibrosis and possibly effective for kidney damage from amphotericin B, though those are specialized medical uses.

The evidence, ingredient by ingredient Vitamin B12 Black Psyllium Apple Cider Vinegar Sodium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin B12 is generally well tolerated orally with no established upper limit — excess is removed in urine. Allergic reactions like rash are rare.

B12 is safe in pregnancy and breastfeeding at recommended amounts. Apple cider vinegar in food amounts is generally well tolerated, but large doses or long-term use may cause harm, including low potassium, high renin levels, and bone loss.

There isn't much safety data on large supplement doses. Sodium is essential in small amounts but too much is linked to high blood pressure and heart strain; avoid sodium supplements or very high intake without your doctor's OK.

Side effects, ingredient by ingredient Vitamin B12 Black Psyllium Apple Cider Vinegar Sodium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Black Psyllium, Apple Cider Vinegar, Vitamin B12, Sodium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; heart-rhythm medications; lithium.
  • For scale: 2,064 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check before starting if you take blood pressure medicine (antihypertensive drugs), corticosteroids, lithium, heart medication (digoxin), insulin, antidiabetes drugs, or diuretics. These carry Moderate interaction risks.

Also mention if you're on metformin — B12 may be affected. Check the search tool on this page with your exact medication names.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

If you take metformin, any blood pressure medicine, heart medication, insulin, diuretic, corticosteroid, or lithium, check your exact drugs with the tool on this page before starting. The sodium and apple cider vinegar in this product carry real interaction risks with common medications.

Talk to your pharmacist before you begin — they can tell you if it's OK for your specific situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor, straight from the product label.

Brand Ee Essential elements
Barcode (UPC) X0036EWQC3S
Net contents 60 Gummy(ies)
Market status On market
Date entered into DSLD Jul 25, 2024
DSLD ID 310235
Product type Botanical With Nutrients
Supplement form Gummy Or Jelly
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor by Ee Essential elements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gummy(ies)
Maximum serving Sizes:
2 Gummy(ies)
Servings per container
30
UPC/BARCODE
X0036EWQC3S
IngredientAmount% DV
Calories10 Calorie(s)--
Total Carbohydrates5 Gram(s)2%
Vitamin B122.4 mcg100%
Dietary Fiber2 Gram(s)7%
Apple Cider Vinegar1000 mg--
Sodium15 mg1%

Other ingredients: organic Tapioca Fiber syrup, Allulose, Water, Pectin, Citric Acid, Natural Flavors, Malic Acid, Stevia, Beet, Powder, Sunflower Oil, Carnauba Wax

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Adults take two (2) gummies once (1x) daily, preferably with a meal, or as recommended by a healthcare professional.

Store in a cool, dry place.

Precautions

Warning: Do not use if you are pregnant, attempting to become pregnant, or nursing. Consult a healthcare professional before using this or any other dietary supplement, especially if you have or suspect you may have any medical condition, or if you are taking anticoagulants, any other dietary supplement, prescription, or over-the-counter medications, as combining these products may cause side effects.

Discontinue use and immediately call a healthcare professional if you experience any adverse reactions. Do not exceed recommended serving. Read entire label prior to use. Do not use if safety seal is damaged or missing.

Keep out of reach of individuals under the age of 18.

Seals/Symbols

GMP Good Manufacturing Practice

Formulation

Preservative free

Zero-sugar

Manufactured in the USA with globally-sourced ingredients.

Non-GMO Zero-sugar Dairy-free Soy-free Gluten-free

General Statements

Questions? (888) 343-9888

Follow us: Facebook Instagram @EssentialElementsNutrition

Formula

Acv With pure ACV from "The Mother" 1000 mg of ACV per serving Fortified with vitamin B12

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor by Ee Essential elements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor by Ee Essential elements

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Gummy(ies) Dosage formGummy Or Jelly Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin B12

Interacts with
20 drugs
2.4 mcg per serving Form: Cyanocobalamin

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very h...

Vitamin B12 monograph & interactions

Dietary Fiber

Interacts with
2,025 drugs
2 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions

Apple Cider Vinegar

Interacts with
162 drugs
1000 mg per serving

Apple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of...

Apple Cider Vinegar monograph & interactions

Sodium

Interacts with
205 drugs
15 mg per serving Form: Sodium Citrate

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Other (inactive) ingredients: Organic Tapioca Fiber syrup, Allulose, Water, Pectin, Citric Acid, Natural Flavors, Malic Acid, Stevia, Beet, Powder, Sunflower Oil, Carnauba Wax. These complete the product’s ingredient list but are not active constituents.

Interaction report

Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor by Ee Essential elements Drug Interactions

Want to check YOUR meds against Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,063Drugs
248 Moderate 1,815 Minor

Ingredients driving the most interactions

Dietary Fiber 2,025
Sodium 205
Apple Cider Vinegar 162
Vitamin B12 20

Individual Drug Interactions

The ingredients in Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor interact with 2,063 drugs. Click any drug to see the details.

4 of the 4 ingredients in Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Sodium Apple Cider Vinegar Vitamin B12

Each ingredient & the kinds of drugs it affects

For each ingredient in Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B
Dietary Fiber full monograph & interactions

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium full monograph & interactions

Apple Cider Vinegar4 drug types · 162 drugs

Digoxin (Lanoxin)

Theoretically, concomitant use of apple cider vinegar with digoxin might increase the risk of cardiac toxicity.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar could decrease potassium levels, increasing the risk of toxicity with digoxin.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. There is some concern that people taking apple cider vinegar along with potassium depleting diuretics might have an increased risk for hypokalemia.

Likelihood Possible Evidence D
Insulin

Theoretically, concomitant use of apple cider vinegar with insulin might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar concomitantly with insulin might increase the risk of hypokalemia.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking apple cider vinegar with antidiabetes drugs might increase the risk of hypoglycemia.
Apple cider vinegar might reduce fasting and postprandial blood glucose levels and decrease gastric emptying in people with diabetes. However, not all research agrees. Theoretically, it might have additive effects on glucose levels when used with antidiabetes drugs.

Likelihood Possible Evidence B
Apple Cider Vinegar full monograph & interactions

Vitamin B121 drug type · 20 drugs

Metformin (Glucophage)

Metformin, a common medication used to manage type 2 diabetes, has been associated with lower vitamin B12 levels in some individuals. Prolonged use of metformin can interfere with the absorption of B12 in the digestive system, potentially leading to a deficiency in this essential vitamin.

Likelihood Possible Evidence A
Vitamin B12 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor, from the product label.

Ee Essential elements

See all Ee Essential elements products
Name
Essential Elements
City
Lindon
State
UT
ZipCode
84042
Phone Number
(888) 343-9888
Web Address
www.Ee.fit
Pharmacist Counseling Corner

Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor by Ee Essential elements: Common Questions

Does Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor by Ee Essential elements interact with any medications?
Yes. Based on its ingredients, Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor has a known interaction with 2,063 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take if I'm on metformin?
Metformin can lower B12 levels over time by interfering with how your body absorbs it. This product contains B12, so there's a Minor interaction to watch. Your doctor or pharmacist can advise whether the B12 here would help or if you need a different approach — don't skip this conversation.
Can I take this if I'm on a blood pressure medicine?
The sodium in this product may reduce how well your blood pressure medicine works. Check your exact medication on this page's search tool before starting, and mention it to your pharmacist or doctor.
What does the B12 in this do?
B12 is used to treat B12 deficiency and is effective for that. It's also possibly effective for canker sores and nerve pain. Your body needs it for nerve and blood cell health, and it's safe at recommended amounts in pregnancy and breastfeeding.
Is apple cider vinegar actually proven to work?
The evidence for apple cider vinegar's effects on acne, skin, brain function, dental health, and mood isn't established in our data yet. The main component here is apple cider vinegar at 1000 mg, but we don't have strong evidence to support those common claims.
Are there any common side effects?
B12 is generally well tolerated when taken by mouth. Apple cider vinegar in food amounts is well tolerated, but in larger doses or long-term use it can cause low potassium and other issues. Allergic reactions to B12 are rare.
Is this OK if I'm pregnant or breastfeeding?
B12 is safe in pregnancy and breastfeeding at recommended amounts. There's not enough safety data on file for apple cider vinegar at supplement doses in pregnancy or lactation — talk with your doctor or midwife for personalized advice.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor label
Go deeper

The Full Monographs Behind Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin B12

Interacts with 20 drugs

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very helpful for people who are deficient — su...

Read the full Vitamin B12 monograph → Herb & supplement monograph

Black Psyllium

Interacts with 2,025 drugs

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...

Read the full Black Psyllium monograph → Herb & supplement monograph

Apple Cider Vinegar

Interacts with 162 drugs

Apple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of these uses is limited and mixed, and the...

Read the full Apple Cider Vinegar monograph → Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph →
Sources

Sources & How We Checked

Apple Cider Vinegar Gummies 1000 mg Zero-Sugar Red Apple Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 97 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin B12 30 references
  1. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  2. Hartman TJ, Woodson K, Stolzenberg-Solomon R, et al. Association of the B-vitamins pyridoxal 5'-phosphate (B6), B12, and folate with lung cancer risk in older men. Am J Epidemiol 2001;153:688-94.. DOI
  3. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  4. Lange H, Suryapranata H, De Luca G, et al. Folate therapy and in-stent restenosis after coronary stenting. N Engl J Med 2004;350:2673-81. PubMed
  5. Collin, S. M., Metcalfe, C., Refsum, H., Lewis, S. J., Zuccolo, L., Smith, G. D., Chen, L., Harris, R., Davis, M., Marsden, G., Johnston, C., Lane, J. A., Ebbing, M., Bonaa, K. H., Nygard, O., Ueland, P. M., Grau, M. V., Baron, J. A., Donovan, J. L., Nea
  6. Geissbuhler, P., Mermillod, B., and Rapin, C. H. Elevated serum vitamin B12 levels associated with CRP as a predictive factor of mortality in palliative care cancer patients: a prospective study over five years. J.Pain Symptom.Manage. 2000;20(2):93-103. PubMed
  7. Salles, N., Herrmann, F., Sakbani, K., Rapin, C. H., and Sieber, C. High vitamin B12 level: a strong predictor of mortality in elderly inpatients. J Am Geriatr.Soc 2005;53(5):917-918.
  8. Looker, H. C., Fagot-Campagna, A., Gunter, E. W., Pfeiffer, C. M., Sievers, M. L., Bennett, P. H., Nelson, R. G., Hanson, R. L., and Knowler, W. C. Homocysteine and vitamin B(12) concentrations and mortality rates in type 2 diabetes. Diabetes Metab Res R
  9. Uhl, W., Nolting, A., Golor, G., Rost, K. L., and Kovar, A. Safety of hydroxocobalamin in healthy volunteers in a randomized, placebo-controlled study. Clin Toxicol (Phila) 2006;44 Suppl 1:17-28. PubMed
  10. Borron, S. W., Baud, F. J., Barriot, P., Imbert, M., and Bismuth, C. Prospective study of hydroxocobalamin for acute cyanide poisoning in smoke inhalation. Ann Emerg.Med 2007;49(6):794-801, 801. PubMed
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Black Psyllium 18 references
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Apple Cider Vinegar 11 references
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See these in context on the Apple Cider Vinegar monograph →

Sodium 38 references
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See these in context on the Sodium monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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